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Danio rerio

8 genes annotated in zebrafish

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negative regulation of cell proliferation

GO:0008285

Any process that stops, prevents or reduces the rate or extent of cell proliferation.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cell proliferation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of cell proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
tbx2b	T-box 2b	0.312
bmp2b	bone morphogenetic protein 2b	0.290	Human Mouse
osr1	odd-skipped related 1 (Drosophila)	0.276
wt1a	wilms tumor 1a	0.212	Human Mouse
tbx1	T-box 1	0.194
fgf3	fibroblast growth factor 3	0.173
gata3	GATA-binding protein 3	0.162	Human Mouse
tp53	tumor protein p53	0.150	Human Mouse
shha	sonic hedgehog a	0.120
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.113	Rat
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.110
mab21l2	mab-21-like 2	0.091
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.080
bmp2a	bone morphogenetic protein 2a	0.079	Human Mouse
pitx3	paired-like homeodomain transcription factor 3	0.076
twist1b	twist1b	0.075
ift88	intraflagellar transport 88 homolog	0.073	Mouse
robo3	roundabout homolog 3	0.067
spry4	sprouty (Drosophila) homolog 4	0.066
tagln2	transgelin 2	0.058
esr1	estrogen receptor 1	0.055	Rat
igf1rb	insulin-like growth factor 1b receptor	0.054
zgc:172136	zgc:172136	0.048
igf1	insulin-like growth factor 1	0.047
fgfr4	fibroblast growth factor receptor 4	0.046
ndr2	nodal-related 2	0.046
mstnb	myostatin b	0.046
fzd5	frizzled homolog 5	0.043	Mouse
sox17	SRY-box containing gene 17	0.042	Fly
gata6	GATA-binding protein 6	0.042
tgfb1a	transforming growth factor, beta 1a	0.042	Human Mouse Rat
foxi1	forkhead box I1	0.041
zeb2a	zinc finger E-box binding homeobox 2a	0.039
myod1	myogenic differentiation 1	0.038	Mouse
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.037
cdh1	cadherin 1, epithelial	0.037	Mouse
evx1	even-skipped homeobox 1	0.035
lhx1a	LIM homeobox 1a	0.035
pitx2	paired-like homeodomain transcription factor 2	0.034
mych	myelocytomatosis oncogene homolog	0.034
matn4	matrilin 4	0.033
flh	floating head	0.033
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.032
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.032
myca	myelocytomatosis oncogene a	0.032
pkd2	polycystic kidney disease 2	0.031
fabp11a	fatty acid binding protein 11a	0.031
chd	chordin	0.030
foxa3	forkhead box A3	0.030	Rat
btg1	B-cell translocation gene 1	0.029	Human
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.029
tgfbi	transforming growth factor, beta-induced	0.029
zdhhc8b	zinc finger, DHHC-type containing 8b	0.028
fstl1a	follistatin-like 1a	0.028
gata5	GATA-binding protein 5	0.028
acvr1l	activin A receptor, type I like	0.027
arhgef7b	Rho guanine nucleotide exchange factor (GEF) 7b	0.027
irf6	interferon regulatory factor 6	0.026	Mouse
bcl2	B-cell leukemia/lymphoma 2	0.026	Mouse
dzip1	DAZ interacting protein 1	0.026
csrp1a	cysteine and glycine-rich protein 1a	0.025
unc45a	unc-45 homolog A (C. elegans)	0.025
sox2	SRY-box containing gene 2	0.025	Human
irx5a	iroquois homeobox protein 5a	0.025
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.024
LOC100003330	melanocortin-2 receptor accessory protein 2-like	0.024
tpm4	tropomyosin 4	0.024
hoxd4a	homeo box D4a	0.024
mib	mind bomb	0.023
slc4a2a	solute carrier family 4, anion exchanger, member 2a	0.023
th	tyrosine hydroxylase	0.023
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.023
gpia	glucose phosphate isomerase a	0.023
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.023
gata2a	GATA-binding protein 2a	0.023	Human Mouse
neurog1	neurogenin 1	0.022
gdf11	growth differentiation factor 11	0.021	Mouse
fgf24	fibroblast growth factor 24	0.021
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.021
cd63	Cd63 antigen	0.021
sox32	SRY-box containing gene 32	0.021	Fly
efnb3b	ephrin B3b	0.019
ctgf	connective tissue growth factor	0.019
lft1	lefty1	0.018	Mouse
tal1	T-cell acute lymphocytic leukemia 1	0.018
irx1a	iroquois homeobox protein 1, a	0.018
junb	jun B proto-oncogene	0.018
tp63	tumor protein p63	0.018
pdlim1	PDZ and LIM domain 1 (elfin)	0.018
sox4b	SRY-box containing gene 4b	0.018
inhbaa	inhibin, beta Aa	0.018	Human
foxo3b	forkhead box O3b	0.018	Fly
ilk	integrin linked kinase	0.018	Mouse Rat
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.017
tcf12	transcription factor 12	0.017
dusp6	dual specificity phosphatase 6	0.017
efna3b	ephrin A3b	0.017
ywhai	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide	0.016
six4.3	sine oculis homeobox homolog 4.3	0.016	Mouse
fzd7a	frizzled homolog 7a	0.016
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.016
midn	midnolin	0.015
ripk2	receptor-interacting serine-threonine kinase 2	0.015
mafl	v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L	0.015
prox1	prospero-related homeobox gene 1	0.015	Mouse Fly
xirp1	xin actin-binding repeat containing 1	0.015	Mouse
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.015	Human Mouse
ptena	phosphatase and tensin homolog A	0.015	Human Mouse
wnt10a	wingless-type MMTV integration site family, member 10a	0.015
fgf4	fibroblast growth factor 4	0.015
fgf8a	fibroblast growth factor 8 a	0.015
fgf10a	fibroblast growth factor 10a	0.015	Mouse
edn1	endothelin 1	0.014
met	met proto-oncogene (hepatocyte growth factor receptor)	0.014
sox1a	SRY-box containing gene 1a	0.014
bmp4	bone morphogenetic protein 4	0.014	Human Mouse
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.014
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.014
nog1	noggin 1	0.014	Mouse
hdac4	histone deacetylase 4	0.014	Mouse
alcama	activated leukocyte cell adhesion molecule a	0.013
znf703	zinc finger protein 703	0.013
nkx2.2b	NK2 transcription factor related 2b	0.013
her12	hairy-related 12	0.013
mtp	microsomal triglyceride transfer protein	0.013
six3b	sine oculis homeobox homolog 3b	0.013
itgb1a	integrin, beta 1a	0.013
sid4	secreted immunoglobulin domain 4	0.013
vax2	ventral anterior homeobox 2	0.013
jak1	Janus kinase 1	0.013
igf2b	insulin-like growth factor 2b	0.013
chst11	carbohydrate (chondroitin 4) sulfotransferase 11	0.013
dkk1b	dickkopf 1b	0.013
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.012
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.012
efna5a	ephrin A5a	0.012
fgf17	fibroblast growth factor 17	0.012
sh3gl1b	SH3-domain GRB2-like 1b	0.012
jup	junction plakoglobin	0.012
alas2	aminolevulinate, delta-, synthetase 2	0.012
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.012	Zebrafish
dynlrb1	dynein, light chain, roadblock-type 1	0.011
egr1	early growth response 1	0.011
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.011
maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)	0.011
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.011
pak2a	p21 (CDKN1A)-activated kinase 2a	0.011
slit2	slit (Drosophila) homolog 2	0.011	Mouse
zgc:77051	zgc:77051	0.011
zgc:123180	zgc:123180	0.011
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.011
loxl2b	lysyl oxidase-like 2b	0.011
mapk1	mitogen-activated protein kinase 1	0.011
apoeb	apolipoprotein Eb	0.011	Human
jun	jun proto-oncogene	0.011	Mouse
tgfb3	transforming growth factor, beta 3	0.011	Mouse Rat
zgc:86598	zgc:86598	0.011
eya1	eyes absent homolog 1	0.011
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.010
bmp3	bone morphogenetic protein 3	0.010
ctsk	cathepsin K	0.010
gpx1a	glutathione peroxidase 1a	0.010
klf4a	Kruppel-like transcription factor 4a	0.010
irx3a	iroquois homeobox protein 3a	0.010
agtr2	angiotensin II receptor, type 2	0.010
pax6a	paired box gene 6a	0.010	Mouse
pdx1	pancreatic and duodenal homeobox 1	0.010	Mouse
anxa11b	annexin A11b	0.010
krt4	keratin 4	0.010	Mouse
wnt1	wingless-type MMTV integration site family, member 1	0.010
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.010
pde10a	phosphodiesterase 10A	0.010
vent	ventral expressed homeobox	0.010
stc1l	stanniocalcin 1, like	0.010
wnt5b	wingless-type MMTV integration site family, member 5b	0.010	Human Mouse