IMP

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Danio rerio

2 genes annotated in zebrafish

Multi-species View

negative regulation of tor signaling

GO:0032007

Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of tor signaling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of tor signaling" (in gray)

Name	Description	Probability	Func Analog Organism
ocrl	oculocerebrorenal syndrome of Lowe	0.435
prickle2	prickle-like 2 (Drosophila)	0.288
tm9sf2	transmembrane 9 superfamily member 2	0.198
cry2b	cryptochrome 2b	0.176
cdc14aa	CDC14 cell division cycle 14 homolog A, a	0.144
nf1a	neurofibromin 1a	0.142
trpc4apa	transient receptor potential cation channel, subfamily C, member 4 associated protein a	0.132
arntl1a	aryl hydrocarbon receptor nuclear translocator-like 1a	0.129	Mouse
homez	homeodomain leucine zipper gene	0.125
im:7163520	im:7163520	0.106
acvr1b	activin A receptor, type IB	0.102
lpp	LIM domain containing preferred translocation partner in lipoma	0.100
zgc:64114	zgc:64114	0.096	Human Mouse
zfyve28	zinc finger, FYVE domain containing 28	0.087
rnf40	ring finger protein 40	0.086
mark3	MAP/microtubule affinity-regulating kinase 3	0.082
tfe3b	transcription factor binding to IGHM enhancer 3b	0.080
sc:d411	sc:d411	0.079
clock3	clock homolog 3 (mouse)	0.078
vcana	versican a	0.077
faslg	Fas ligand (TNF superfamily, member 6)	0.076
sbf1	SET binding factor 1	0.076
casc3	cancer susceptibility candidate 3	0.075
itga3b	integrin, alpha 3b	0.066
c11orf2	c11orf2 homolog (H. sapiens)	0.062
si:ch73-60e21.1	si:ch73-60e21.1	0.061
brd2a	bromodomain-containing 2a	0.061
mstna	myostatin a	0.060
sec24c	SEC24 family, member C (S. cerevisiae)	0.058
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.058
atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.056
mical2b	microtubule associated monoxygenase, calponin and LIM domain containing 2b	0.053
si:dkey-24l11.7	si:dkey-24l11.7	0.051
per3	period homolog 3 (Drosophila)	0.050
zdhhc8b	zinc finger, DHHC-type containing 8b	0.049
si:dkey-175m17.8	si:dkey-175m17.8	0.049
shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.049
sart3	squamous cell carcinoma antigen recognised by T cells 3	0.049
pou2f1a	POU class 2 homeobox 1a	0.047
pld1a	phospholipase D1a	0.047
trim13	tripartite motif-containing 13	0.046
si:ch211-239j15.4	si:ch211-239j15.4	0.046
insra	insulin receptor a	0.045
arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.044
etfa	electron-transfer-flavoprotein, alpha polypeptide	0.043
klhl11	kelch-like 11 (Drosophila)	0.042
slu7	SLU7 splicing factor homolog (S. cerevisiae)	0.042
midn	midnolin	0.040
gon4l	gon-4-like (C.elegans)	0.040
cry4	cryptochrome 4	0.039
zgc:172136	zgc:172136	0.038
clasp2	cytoplasmic linker associated protein 2	0.038
arntl2	aryl hydrocarbon receptor nuclear translocator-like 2	0.036
im:7164961	im:7164961	0.035
gyltl1b	glycosyltransferase-like 1b	0.035
zmynd19	zinc finger, MYND domain containing 19	0.033
insrb	insulin receptor b	0.033
tfe3a	transcription factor binding to IGHM enhancer 3a	0.033
rmnd5b	required for meiotic nuclear division 5 homolog B (S. cerevisiae)	0.032
si:ch211-272f3.4	si:ch211-272f3.4	0.031
she	Src homology 2 domain containing E	0.031
aldh2b	aldehyde dehydrogenase 2b	0.031
agbl5	ATP/GTP binding protein-like 5	0.031
si:dkey-12o15.1	si:dkey-12o15.1	0.030
fut10	fucosyltransferase 10	0.029
igf2b	insulin-like growth factor 2b	0.029
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.029
sec23ip	SEC23 interacting protein	0.029
znf148	zinc finger protein 148	0.029
cdc16	cell division cycle 16 homolog (S. cerevisiae)	0.028
sox9b	SRY-box containing gene 9b	0.028
zgc:55936	zgc:55936	0.027
sirt1	sirtuin (silent mating type information regulation 2 homolog) 1	0.027
stat3	signal transduction and activation of transcription 3	0.027
tmem170a	transmembrane protein 170A	0.026
zgc:55634	zgc:55634	0.026
arfgap2	ADP-ribosylation factor GTPase activating protein 2	0.026
usp25	ubiquitin specific protease 25	0.026
ero1l	ERO1-like (S. cerevisiae)	0.025
ggnbp2	gametogenetin binding protein 2	0.025
hcst	hematopoietic cell signal transducer	0.025
hic1l	hypermethylated in cancer 1 like	0.025
klhl18	kelch-like 18 (Drosophila)	0.025
rxrba	retinoid x receptor, beta a	0.025
znf711	zinc finger protein 711	0.024
ankrd13c	ankyrin repeat domain 13C	0.024
npepps	aminopeptidase puromycin sensitive	0.024
fcho2	FCH domain only 2	0.024
dixdc1b	DIX domain containing 1b	0.024
ccnt2a	cyclin T2a	0.024
LOC559090	PWWP domain-containing protein 2A-like	0.024
esama	endothelial cell adhesion molecule a	0.024
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.024
ptprk	protein tyrosine phosphatase, receptor type, K	0.024
brap	BRCA1 associated protein	0.023
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.023
dusp4	dual specificity phosphatase 4	0.023
snai2	snail homolog 2 (Drosophila)	0.023
cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.023
zgc:123180	zgc:123180	0.023
zgc:158564	zgc:158564	0.022
rspry1	ring finger and SPRY domain containing 1	0.022
kdsr	3-ketodihydrosphingosine reductase	0.022
tmem57a	transmembrane protein 57a	0.022
wwp1	WW domain containing E3 ubiquitin protein ligase 1	0.022
si:dkeyp-34c12.2	si:dkeyp-34c12.2	0.022
waca	WW domain containing adaptor with coiled-coil a	0.022
si:dkeyp-51f11.8	si:dkeyp-51f11.8	0.022
LOC564872	monocarboxylate transporter 7-like	0.022
atxn7l2b	ataxin 7-like 2b	0.021
ptpra	protein tyrosine phosphatase, receptor type, A	0.021
zgc:101679	zgc:101679	0.021
rps6kal	ribosomal protein S6 kinase, like	0.021
als2b	amyotrophic lateral sclerosis 2b (juvenile)	0.021
zgc:55558	zgc:55558	0.021
celf1	cugbp, Elav-like family member 1	0.021
serinc5	serine incorporator 5	0.021
pomt1	protein-O-mannosyltransferase 1	0.021
ggps1	geranylgeranyl diphosphate synthase 1	0.021
stk40	serine/threonine kinase 40	0.021
rictor	RPTOR independent companion of MTOR, complex 2	0.021
arih2	ariadne homolog 2 (Drosophila)	0.021
slc2a8	solute carrier family 2 (facilitated glucose transporter), member 8	0.020
cdk5	cyclin-dependent protein kinase 5	0.020
rab22a	RAB22A, member RAS oncogene family	0.020
uvrag	UV radiation resistance associated gene	0.020
fbxo32	F-box protein 32	0.020
kdm5c	lysine (K)-specific demethylase 5C	0.020
rgp1	RGP1 retrograde golgi transport homolog (S. cerevisiae)	0.020
wu:fc31g04	wu:fc31g04	0.020
sars	seryl-tRNA synthetase	0.020
cecr1a	cat eye syndrome chromosome region, candidate 1a	0.019
igf1rb	insulin-like growth factor 1b receptor	0.019
zgc:193699	zgc:193699	0.019
zgc:77655	zgc:77655	0.019
bad	BCL2-antagonist of cell death	0.019
ahcyl2	S-adenosylhomocysteine hydrolase-like 2	0.019
ewsr1b	Ewing sarcoma breakpoint region 1b	0.019
foxe3	forkhead box E3	0.019
or111-11	odorant receptor, family D, subfamily 111, member 11	0.019
slka	STE20-like kinase a	0.019
mapk3	mitogen-activated protein kinase 3	0.019
apaf1	apoptotic protease activating factor 1	0.019
vps39	vacuolar protein sorting 39 homolog (S. cerevisiae)	0.019
zgc:56538	zgc:56538	0.018
mtmr8	myotubularin related protein 8	0.018
zgc:73328	zgc:73328	0.018
kbtbd8	kelch repeat and BTB (POZ) domain containing 8	0.018
arfgef1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.018
bactin1	bactin1	0.018
bnc1	basonuclin 1	0.018
fbxw2	F-box and WD repeat domain containing 2	0.018
elf2b	E74-like factor 2b (ets domain transcription factor)	0.018
atxn7l3	ataxin 7-like 3	0.017
myo6b	myosin VIb	0.017
kctd10	potassium channel tetramerisation domain containing 10	0.017
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.017
b4galt6	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6	0.017
si:rp71-39b20.7	si:rp71-39b20.7	0.017
igf3	insulin-like growth factor 3	0.017
ssrp1b	structure specific recognition protein 1b	0.016
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.016
zgc:194800	zgc:194800	0.016
zgc:63569	zgc:63569	0.016
alg1	asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase)	0.016
LOC562487	e3 ubiquitin-protein ligase RNF12-A-like	0.016
tmf1	TATA element modulatory factor 1	0.016
si:ch211-114c12.2	si:ch211-114c12.2	0.016
nf1b	neurofibromin 1b	0.016
zgc:101761	zgc:101761	0.016
tmbim1	transmembrane BAX inhibitor motif containing 1	0.016
cnot1	CCR4-NOT transcription complex, subunit 1	0.016
ck2a2a	casein kinase 2 alpha 2a	0.016
cnot10	CCR4-NOT transcription complex, subunit 10	0.016
ecd	ecdysoneless homolog (Drosophila)	0.016
stk35l	serine/threonine kinase 35, like	0.016
mpp6b	membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)	0.015
tbc1d23	TBC1 domain family, member 23	0.015
pofut2	protein O-fucosyltransferase 2	0.015
vps26bl	vacuolar protein sorting 26 homolog B, like	0.015
ptpn13	protein tyrosine phosphatase, non-receptor type 13	0.015
ef1a	elongation factor 1-alpha	0.015
sec63	SEC63-like (S. cerevisiae)	0.015
ppp2r5ea	protein phosphatase 2, regulatory subunit B', epsilon isoform a	0.015
dda1	DET1 and DDB1 associated 1	0.015
si:dkey-42i9.10	si:dkey-42i9.10	0.015
vps52	vacuolar protein sorting 52 (yeast)	0.015
htt	huntingtin	0.015
alg3	asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)	0.015
rasgef1ba	RasGEF domain family, member 1Ba	0.014
eya4	eyes absent homolog 4 (Drosophila)	0.014
zgc:56556	zgc:56556	0.014
hsf2	heat shock factor 2	0.014
prdm9	PR domain containing 9	0.014
si:ch211-261f7.2	si:ch211-261f7.2	0.014
tada3l	transcriptional adaptor 3 (NGG1 homolog, yeast)-like	0.014
azin1a	antizyme inhibitor 1a	0.014
rrm2b	ribonucleotide reductase M2 b	0.014
pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.014
siah2l	seven in absentia homolog 2 (Drosophila)-like	0.014
cry2a	cryptochrome 2a	0.014
tfg	trk-fused gene	0.014
notch3	notch homolog 3	0.014
acsl3b	acyl-CoA synthetase long-chain family member 3b	0.014
mtmr6	myotubularin related protein 6	0.014
letm1	leucine zipper-EF-hand containing transmembrane protein 1	0.014
elmo1	engulfment and cell motility 1 (ced-12 homolog, C. elegans)	0.014
snx27	sorting nexin family member 27	0.014
mxi1	max interacting protein	0.014
atg12	ATG12 autophagy related 12 homolog (S. cerevisiae)	0.013
slc26a5	solute carrier family 26, member 5	0.013
mfn2	mitofusin 2	0.013
ubin	ataxin-1 ubiquitin-like interacting protein	0.013
sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.013
sept6	septin 6	0.013
entpd4	ectonucleoside triphosphate diphosphohydrolase 4	0.013
irgq1	immunity-related GTPase family, q1	0.013
pex5	peroxisomal biogenesis factor 5	0.013
arntl1b	aryl hydrocarbon receptor nuclear translocator-like 1b	0.013	Mouse
mapk14a	mitogen-activated protein kinase 14a	0.013
gsk3a	glycogen synthase kinase 3 alpha	0.013
tmem115	transmembrane protein 115	0.013
abca5	ATP-binding cassette, sub-family A (ABC1), member 5	0.013
LOC100535549	cytoplasmic polyadenylation element-binding protein 4-like	0.013
epas1b	endothelial PAS domain protein 1b	0.013
grhl2a	grainyhead-like 2a (Drosophila)	0.013
pias4b	protein inhibitor of activated STAT, 4b	0.013
pdia5	protein disulfide isomerase family A, member 5	0.013
sult3st1	sulfotransferase family 3, cytosolic sulfotransferase 1	0.013
ell	elongation factor RNA polymerase II	0.013
ubap1	ubiquitin associated protein 1	0.013
zgc:55448	zgc:55448	0.013
abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.013
ryk	receptor-like tyrosine kinase	0.013
mcrs1	microspherule protein 1	0.013
sps2	selenophosphate synthetase 2	0.012
fbxo42	F-box protein 42	0.012
si:ch211-160j6.2	si:ch211-160j6.2	0.012
march6	membrane-associated ring finger (C3HC4) 6	0.012
pomt2	protein-O-mannosyltransferase 2	0.012
zbtb4	zinc finger and BTB domain containing 4	0.012
igf2a	insulin-like growth factor 2a	0.012
fbxw11b	F-box and WD-40 domain protein 11b	0.012	Fly
arih1l	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like	0.012
vegfab	vascular endothelial growth factor Ab	0.012
ctage5	CTAGE family, member 5	0.012
ftsjd1	FtsJ methyltransferase domain containing 1	0.012
hspb6	heat shock protein, alpha-crystallin-related, b6	0.012
mmd2	progestin and adipoQ receptor 10	0.012
casp9	caspase 9, apoptosis-related cysteine protease	0.012
chic2	cysteine-rich hydrophobic domain 2	0.012
znf143	zinc finger protein 143	0.012
dirc2	disrupted in renal carcinoma 2	0.012
si:ch211-255l12.1	si:ch211-255l12.1	0.012
btg1	B-cell translocation gene 1	0.012
ctnnd2a	catenin (cadherin-associated protein), delta 2a	0.012
thraa	thyroid hormone receptor alpha a	0.012
exoc3	exocyst complex component 3	0.012
nudt22	nudix (nucleoside diphosphate linked moiety X)-type motif 22	0.012
si:ch211-198a12.6	si:ch211-198a12.6	0.012
hnrpdl	heterogeneous nuclear ribonucleoprotein D-like	0.012
cutl1	cut-like 1 (Drosophila)	0.012
zfr	zinc finger RNA binding protein	0.012
wu:fi25h02	wu:fi25h02	0.012
exoc7	exocyst complex component 7	0.012
zgc:152984	zgc:152984	0.012
kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.012
cmtm4	CKLF-like MARVEL transmembrane domain containing 4	0.012
tjp2a	tight junction protein 2a (zona occludens 2)	0.012
slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	0.011
pid1	phosphotyrosine interaction domain containing 1	0.011
fam125ba	family with sequence similarity 125, member B, duplicate a	0.011
dnajc24	DnaJ (Hsp40) homolog, subfamily C, member 24	0.011
cpeb4	cytoplasmic polyadenylation element binding protein 4	0.011
kcmf1	potassium channel modulatory factor 1	0.011
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.011
kiss1	KiSS-1 metastasis-suppressor	0.011
zgc:162945	zgc:162945	0.011
cbsb	cystathionine-beta-synthase b	0.011
LOC100148748	CDK5 and ABL1 enzyme substrate 2-like	0.011
hectd1	HECT domain containing 1	0.011
sb:cb911	sb:cb911	0.011
smad2	MAD homolog 2 (Drosophila)	0.011
tmem110	transmembrane protein 110	0.011
zgc:101785	zgc:101785	0.011
lrrc6	leucine rich repeat containing 6	0.011
pthlh	parathyroid hormone-like hormone	0.011
plk2a	polo-like kinase 2a (Drosophila)	0.011
dennd5b	DENN/MADD domain containing 5B	0.011
im:7138016	im:7138016	0.011
si:ch211-260p9.1	si:ch211-260p9.1	0.011
scaf11	SR-related CTD-associated factor 11	0.011
wdfy1	WD repeat and FYVE domain containing 1	0.011
bbc3	BCL2 binding component 3	0.011
flii	flightless I homolog (Drosophila)	0.011
jhdm1da	jumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae)	0.011
igfbp2b	insulin-like growth factor binding protein 2b	0.011
ptgs1	prostaglandin-endoperoxide synthase 1	0.011
bbs7	Bardet-Biedl syndrome 7	0.011
zgc:112084	zgc:112084	0.011
fam63a	family with sequence similarity 63, member A	0.011
ubxn6	UBX domain protein 6	0.011
fmr1	fragile X mental retardation 1	0.011
LOC555163	myelin protein zero-like protein 1-like	0.011
sec14l1	SEC14-like 1 (S. cerevisiae)	0.011
calub	calumenin b	0.011
zbed4	zinc finger, BED domain containing 4	0.011
zgc:153454	zgc:153454	0.011
max	myc-associated factor X	0.011
si:ch211-284e13.2	si:ch211-284e13.2	0.010
mbtps1	membrane-bound transcription factor protease, site 1	0.010
shisa2	shisa homolog 2 (Xenopus laevis)	0.010
sppl3	signal peptide peptidase 3	0.010
LOC100332039	ectonucleotide pyrophosphatase/phosphodiesterase family member 2-like	0.010
wu:fi37d12	wu:fi37d12	0.010
si:dkey-175c11.1	si:dkey-175c11.1	0.010
lass2	LAG1 homolog, ceramide synthase 2 (S. cerevisiae)	0.010
cwc25	CWC25 spliceosome-associated protein homolog (S. cerevisiae)	0.010
actr8	ARP8 actin-related protein 8 homolog (yeast)	0.010
zgc:111944	zgc:111944	0.010
slc16a9b	solute carrier family 16 (monocarboxylic acid transporters), member 9b	0.010
brd9	bromodomain containing 9	0.010
clybl	citrate lyase beta-like	0.010
stk24b	serine/threonine kinase 24b (STE20 homolog, yeast)	0.010
dachd	dachshund d	0.010
ica	islet cell autoantigen	0.010
prkaa1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.010	Mouse
ntm	neurotrimin	0.010
sgpp1	sphingosine-1-phosphate phosphatase 1	0.010
ikzf5	IKAROS family zinc finger 5	0.010
fign	fidgetin	0.010
ubiad1	UbiA prenyltransferase domain containing 1	0.010