IMP

Process View

Danio rerio

3 genes annotated in zebrafish

pyrimidine containing compound metabolic process

The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "pyrimidine containing compound metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "pyrimidine containing compound metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
dhfr	dihydrofolate reductase	0.314
mthfd1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent)	0.126
mki67ip	mki67 (FHA domain) interacting nucleolar phosphoprotein (human)	0.123
mtr	5-methyltetrahydrofolate-homocysteine methyltransferase	0.105
ddx56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56	0.094
tyms	thymidylate synthase	0.093
pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.089
si:dkey-91i17.1	si:dkey-91i17.1	0.084
zgc:110847	zgc:110847	0.077
si:dkey-1h6.1	si:dkey-1h6.1	0.075
dnmt1	DNA (cytosine-5-)-methyltransferase 1	0.074
mapk3	mitogen-activated protein kinase 3	0.071
mthfd2l	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like	0.068
slc25a32a	solute carrier family 25, member 32a	0.066
rfc4	replication factor C (activator 1) 4	0.066
surf6	surfeit 6	0.065
pola2	polymerase (DNA directed), alpha 2	0.064
prim1	primase polypeptide 1	0.062
im:7148292	im:7148292	0.060
mthfd2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	0.058
nop58	NOP58 ribonucleoprotein homolog (yeast)	0.052
fbl	fibrillarin	0.048
rrs1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	0.045
wdr75	WD repeat domain 75	0.045
zff9	zinc finger protein 9	0.044
nup43	nucleoporin 43	0.044
hspd1	heat shock 60kD protein 1 (chaperonin)	0.041
hells	helicase, lymphoid-specific	0.039
rfc3	replication factor C (activator 1) 3	0.038
kpna2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.038
aldh4a1	aldehyde dehydrogenase 4 family, member A1	0.036
ddx18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	0.033
trmt2a	trm2 tRNA methyltransferase 2 homolog A (S. cerevisiae)	0.033
im:6898523	im:6898523	0.032
mcm5	MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)	0.032
pgm3	phosphoglucomutase 3	0.031
zgc:56683	zgc:56683	0.030
pprc1	peroxisome proliferator-activated receptor gamma, coactivator-related 1	0.030
aldh7a1	aldehyde dehydrogenase 7 family, member A1	0.029
slc25a32b	solute carrier family 25, member 32b	0.029
wdr12	WD repeat domain 12	0.027
rpl7l1	ribosomal protein L7-like 1	0.026
pdss1	prenyl (decaprenyl) diphosphate synthase, subunit 1	0.026
celsr1b	cadherin EGF LAG seven-pass G-type receptor 1b	0.025
etf1	eukaryotic translation termination factor 1	0.025
bysl	bystin-like	0.025
noc4l	nucleolar complex associated 4 homolog (S. cerevisiae)	0.024
mapk12	mitogen-activated protein kinase 12	0.024
mre11a	meiotic recombination 11 homolog A (S. cerevisiae)	0.023
impdh2	IMP (inosine monophosphate) dehydrogenase 2	0.023
zgc:112986	zgc:112986	0.022
mak16	MAK16 homolog (S. cerevisiae)	0.022
nol10	nucleolar protein 10	0.021
prdx2	peroxiredoxin 2	0.021
zgc:152830	zgc:152830	0.021
ncapg2	non-SMC condensin II complex, subunit G2	0.021
gins1	GINS complex subunit 1 (Psf1 homolog)	0.020
imp4	IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)	0.020
noc3l	nucleolar complex associated 3 homolog (S. cerevisiae)	0.020
mat1a	methionine adenosyltransferase I, alpha	0.019
dpyd	dihydropyrimidine dehydrogenase	0.019
msh6	mutS homolog 6 (E. coli)	0.019
pole2	polymerase (DNA directed), epsilon 2	0.019
polr1a	polymerase (RNA) I polypeptide A	0.019
tomm40l	translocase of outer mitochondrial membrane 40 homolog, like	0.018
dap3	death associated protein 3	0.018
ints6	integrator complex subunit 6	0.018
si:ch211-93f2.1	si:ch211-93f2.1	0.018
ahctf1	AT hook containing transcription factor 1	0.018
smc4	structural maintenance of chromosomes 4	0.017
LOC567547	5,10-methylenetetrahydrofolate reductase (NADPH)-like	0.017
smc2	structural maintenance of chromosomes 2	0.017
hist1h4l	histone 1, H4, like	0.017
zgc:56429	zgc:56429	0.017
lap3	leucine aminopeptidase 3	0.017
snf8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.017
grwd1	glutamate-rich WD repeat containing 1	0.017
fen1	flap structure-specific endonuclease 1	0.017
si:dkey-25e12.5	si:dkey-25e12.5	0.017
nr1h5	nuclear receptor subfamily 1, group H, member 5	0.017
bicc2	bicaudal C homolog 2	0.017
slc10a2	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	0.016
nfe2l1	nuclear factor, erythroid derived 2,-like 1	0.016
gart	phosphoribosylglycinamide formyltransferase	0.016
pola1	polymerase (DNA directed), alpha 1	0.016
nasp	nuclear autoantigenic sperm protein (histone-binding)	0.016
cyp4t8	cytochrome P450, family 4, subfamily T, polypeptide 8	0.016
cyfip2	cytoplasmic FMR1 interacting protein 2	0.016
mtx1b	metaxin 1b	0.016
mapk6	mitogen-activated protein kinase 6	0.015
sypl2a	synaptophysin-like 2a	0.015
pdia2	protein disulfide isomerase family A, member 2	0.015
si:ch211-89f7.4	si:ch211-89f7.4	0.015
srpr	signal recognition particle receptor (docking protein)	0.015
sult1st3	sulfotransferase family 1, cytosolic sulfotransferase 3	0.015
acy3.2	aspartoacylase (aminocyclase) 3.2	0.015
rrm1	ribonucleotide reductase M1 polypeptide	0.015
slc9a3r1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.015
mapk7	mitogen-activated protein kinase 7	0.015
ftcd	formiminotransferase cyclodeaminase	0.015
clybl	citrate lyase beta-like	0.015
akt2l	v-akt murine thymoma viral oncogene homolog 2, like	0.015
agxt2l1	alanine-glyoxylate aminotransferase 2-like 1	0.015
prps1a	phosphoribosyl pyrophosphate synthetase 1A	0.014
ctps	CTP synthase	0.014	Human
si:dkey-235k4.1	si:dkey-235k4.1	0.014
eif4bb	eukaryotic translation initiation factor 4Bb	0.014
cyp2aa1	cytochrome P450, family 2, subfamily AA, polypeptide 1	0.014
gyg1	glycogenin 1	0.014
zgc:171663	zgc:171663	0.014
wdr3	WD repeat domain 3	0.014
msh2	mutS homolog 2 (E. coli)	0.014
polr1c	polymerase (RNA) I polypeptide C	0.014
nin	ninein (GSK3B interacting protein)	0.014
qars	glutaminyl-tRNA synthetase	0.014
clstn2	calsyntenin 2	0.014
exosc6	exosome component 6	0.014
rars	arginyl-tRNA synthetase	0.014
ccbl1	cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)	0.013
gins2	GINS complex subunit 2	0.013
tbl3	transducin (beta)-like 3	0.013
cdk2	cyclin-dependent kinase 2	0.013
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.013
zgc:110113	zgc:110113	0.013
slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.013
agxta	alanine-glyoxylate aminotransferase a	0.013
aldh9a1a	aldehyde dehydrogenase 9 family, member A1a	0.013
wdhd1	WD repeat and HMG-box DNA binding protein 1	0.013
gpt2l	glutamic pyruvate transaminase (alanine aminotransferase) 2, like	0.013
dhtkd1	dehydrogenase E1 and transketolase domain containing 1	0.013
timm50	translocase of inner mitochondrial membrane 50 homolog (yeast)	0.013
rcc1	regulator of chromosome condensation 1	0.013
pa2g4a	proliferation-associated 2G4, a	0.013
nola1	nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs)	0.013
abcc4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	0.013
apom	apolipoprotein M	0.013
hectd3	HECT domain containing 3	0.013
dhcr7	7-dehydrocholesterol reductase	0.013
tln1	talin 1	0.013
prkcd	protein kinase C, delta	0.012
gnl3	guanine nucleotide binding protein-like 3 (nucleolar)	0.012	Fly
aurkb	aurora kinase B	0.012
im:7150454	im:7150454	0.012
sesn3	sestrin 3	0.012
ppat	phosphoribosyl pyrophosphate amidotransferase	0.012
zgc:66484	zgc:66484	0.012
msi2b	musashi homolog 2b (Drosophila)	0.012
acss1	acyl-CoA synthetase short-chain family member 1	0.012
nle1	notchless homolog 1 (Drosophila)	0.012
zgc:73273	zgc:73273	0.012
tsku	tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)	0.012
zgc:77439	zgc:77439	0.012
rps6ka1	ribosomal protein S6 kinase a, polypeptide 1	0.012
pcdh1a4	protocadherin 1 alpha 4	0.012
abat	4-aminobutyrate aminotransferase	0.012
pes	pescadillo	0.011
clic4	chloride intracellular channel 4	0.011
ak4	adenylate kinase 4	0.011
dut	dUTP pyrophosphatase	0.011
mpdu1a	mannose-P-dolichol utilization defect 1a	0.011
ldhba	lactate dehydrogenase Ba	0.011
trit1	tRNA isopentenyltransferase 1	0.011
ogt.1	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 1	0.011
slc12a7b	solute carrier family 12, member 7b	0.011
pmpca	peptidase (mitochondrial processing) alpha	0.011
pcdh1a6	protocadherin 1 alpha 6	0.011
atp2a2b	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2b	0.011
ppan	peter pan homolog (Drosophila)	0.011
itga7	integrin, alpha 7	0.011
ptprma	protein tyrosine phosphatase, receptor type, M, a	0.011
fam136a	family with sequence similarity 136, member A	0.011
pls1	plastin 1 (I isoform)	0.011
sec13	SEC13 homolog (S. cerevisiae)	0.011
slc37a4a	solute carrier family 37 (glucose-6-phosphate transporter), member 4a	0.011
trmt61a	tRNA methyltransferase 61 homolog A (S. cerevisiae)	0.011
zgc:55420	zgc:55420	0.011
zgc:92432	zgc:92432	0.011
utp15	utp15, U3 small nucleolar ribonucleoprotein, homolog	0.011
acat1	acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)	0.011
selenbp1	selenium binding protein 1	0.011
zgc:110540	zgc:110540	0.011
zgc:136871	zgc:136871	0.011
nip7	nuclear import 7 homolog (S. cerevisiae)	0.011
si:ch211-215l11.5	si:ch211-215l11.5	0.011
si:ch211-14a17.3	si:ch211-14a17.3	0.010
pck2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	0.010
ncapd2	non-SMC condensin I complex, subunit D2	0.010
abcf1	ATP-binding cassette, sub-family F (GCN20), member 1	0.010
nhp2l1	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	0.010
polr3e	polymerase (RNA) III (DNA directed) polypeptide E	0.010
wnt5a	wingless-type MMTV integration site family, member 5a	0.010
fcho2	FCH domain only 2	0.010
slc35b4	solute carrier family 35, member B4	0.010
zgc:92027	zgc:92027	0.010
ahcy	S-adenosylhomocysteine hydrolase	0.010
cd151l	CD151 antigen, like	0.010
si:dkey-177e13.4	si:dkey-177e13.4	0.010
hnmt	histamine N-methyltransferase	0.010
cabin1	calcineurin binding protein 1	0.010
rhd	Rh blood group, D antigen	0.010
nup93	nucleoporin 93	0.010
acox3	acyl-Coenzyme A oxidase 3, pristanoyl	0.010
alad	aminolevulinate dehydratase	0.010