IMP

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Danio rerio

13 genes annotated in zebrafish

non canonical wnt signaling pathway

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "non canonical wnt signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "non canonical wnt signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
wnt4a	wingless-type MMTV integration site family, member 4a	0.688	Zebrafish Mouse
wnt11	wingless-type MMTV integration site family, member 11	0.614
sfrp1a	secreted frizzled-related protein 1a	0.383	Human Mouse
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.260
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.254
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.244	Zebrafish
fzd7a	frizzled homolog 7a	0.241
wnt8b	wingless-type MMTV integration site family, member 8b	0.233	Zebrafish
fzd10	frizzled homolog 10	0.195	Human Zebrafish
wnt9a	wingless-type MMTV integration site family, member 9A	0.173	Zebrafish Fly
dkk1b	dickkopf 1b	0.172
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.172
bon	bonnie and clyde	0.153
wnt5b	wingless-type MMTV integration site family, member 5b	0.153
ephb4b	eph receptor B4b	0.151
wnt10a	wingless-type MMTV integration site family, member 10a	0.150	Zebrafish
fzd7b	frizzled homolog 7b	0.149	Human Zebrafish Mouse
wnt9b	wingless-type MMTV integration site family, member 9B	0.144	Zebrafish Mouse Fly
rest	RE1-silencing transcription factor	0.144
nog1	noggin 1	0.134
wnt3	wingless-type MMTV integration site family, member 3	0.116	Zebrafish
wnt2	wingless-type MMTV integration site family member 2	0.112	Zebrafish
notch3	notch homolog 3	0.111
osr2	odd-skipped related 2 (Drosophila)	0.102
sb:cb81	sb:cb81	0.098
grem1a	gremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis)	0.095
wnt1	wingless-type MMTV integration site family, member 1	0.083	Zebrafish Fly
lft2	lefty2	0.080
spry2	sprouty homolog 2	0.079
tbx1	T-box 1	0.075
sulf1	sulfatase 1	0.072
brd4	bromodomain containing 4	0.071
fgf17	fibroblast growth factor 17	0.070
gli3	GLI-Kruppel family member GLI3	0.070
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.065
spns2	spinster homolog 2 (Drosophila)	0.065
ism1	isthmin 1	0.061
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.061
lrp2	low density lipoprotein-related protein 2	0.058
notum3	notum 3	0.057
admp	anti-dorsalizing morphogenic protein	0.056
celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.056
lhx1b	LIM homeobox 1b	0.054
ppp1r3ca	protein phosphatase 1, regulatory (inhibitor) subunit 3Ca	0.053
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.053
aplnra	apelin receptor a	0.053
zbtb4	zinc finger and BTB domain containing 4	0.052
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.052
gpc4	glypican 4	0.051
mga	MAX gene associated	0.050
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.048
map3k4	mitogen activated protein kinase kinase kinase 4	0.047
flot2a	flotillin 2a	0.046
tmpoa	thymopoietin a	0.046
dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.046
map2k4b	mitogen-activated protein kinase kinase 4b	0.045
itgav	integrin, alpha V	0.045
lft1	lefty1	0.044
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.044	Zebrafish Mouse
dlc	deltaC	0.043
arl13b	ADP-ribosylation factor-like 13b	0.042
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.042
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.042
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.040
wnt3a	wingless-type MMTV integration site family, member 3A	0.040	Zebrafish
bmpr1ab	bone morphogenetic protein receptor, type 1ab	0.039
fstl1a	follistatin-like 1a	0.038
wnt16	wingless-type MMTV integration site family, member 16	0.038
foxa2	forkhead box A2	0.037
fgfr1b	fibroblast growth factor receptor 1b	0.036
fgf3	fibroblast growth factor 3	0.034
ror2	receptor tyrosine kinase-like orphan receptor 2	0.034
prdm14	PR domain containing 14	0.033
frzb	frizzled-related protein	0.032	Zebrafish Worm
znf503	zinc finger protein 503	0.032
fbln1	fibulin 1	0.032
her3	hairy-related 3	0.031
hnf1ba	HNF1 homeobox Ba	0.031
her5	hairy-related 5	0.031
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.030
axin1	axin 1	0.030
waca	WW domain containing adaptor with coiled-coil a	0.030
lrmp	lymphoid-restricted membrane protein	0.029
znf703	zinc finger protein 703	0.028
id1	inhibitor of DNA binding 1	0.028
six2a	sine oculis-related homeobox 2a	0.027
col11a2	collagen type XI alpha-2	0.027
gle1	GLE1 RNA export mediator homolog (yeast)	0.027
sec24d	SEC24 family, member D (S. cerevisiae)	0.027
si:dkey-273o13.1	si:dkey-273o13.1	0.027
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.026
wnt8a	wingless-type MMTV integration site family, member 8a	0.026	Zebrafish
ppp4cb	protein phosphatase 4 (formerly X), catalytic subunit b	0.026
zgc:171495	zgc:171495	0.026
ntn1b	netrin 1b	0.026
wu:fj62d01	wu:fj62d01	0.026
rbm22	RNA binding motif protein 22	0.025
rnd1l	Rho family GTPase 1 like	0.025
otx1b	orthodenticle homolog 1b	0.024
mesp2	mesoderm posterior 2 homolog (mouse)	0.024
gro2	groucho 2	0.024
ext1a	exostoses (multiple) 1a	0.024
pkd2	polycystic kidney disease 2	0.024
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.023
otx1a	orthodenticle homolog 1a	0.023
sfrp1b	secreted frizzled-related protein 1b	0.023	Human Mouse
pea3	ETS-domain transcription factor pea3	0.023
ptgs1	prostaglandin-endoperoxide synthase 1	0.023
nkd1	naked cuticle homolog 1 (Drosophila)	0.023	Mouse
gli1	GLI-Kruppel family member 1	0.023
wif1	wnt inhibitory factor 1	0.023
csnk1g2a	casein kinase 1, gamma 2a	0.022
lhx2b	LIM homeobox 2b	0.022
hoxd4a	homeo box D4a	0.022
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.022
map2k7	mitogen-activated protein kinase kinase 7	0.022
atp6v1g1	ATPase, H+ transporting, V1 subunit G isoform 1	0.021
hbbe3	hemoglobin beta embryonic-3	0.021
bhlhe41	basic helix-loop-helix family, member e41	0.021
smad3b	MAD, mothers against decapentaplegic homolog 3b (Drosophila)	0.021
zgc:66100	zgc:66100	0.021
scrib	scribbled homolog (Drosophila)	0.021
sp5l	Sp5 transcription factor-like	0.021
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.020	Human Mouse Worm
fgf10a	fibroblast growth factor 10a	0.020
lamb1a	laminin, beta 1a	0.020
snapc4	small nuclear RNA activating complex, polypeptide 4	0.020
sema3h	semaphorin 3h	0.019
map2k4a	mitogen-activated protein kinase kinase 4a	0.019
bactin2	bactin2	0.019
wnt5a	wingless-type MMTV integration site family, member 5a	0.019	Zebrafish
flh	floating head	0.018
ift46	intraflagellar transport protein 46	0.018
ihha	Indian hedgehog homolog a	0.018
col2a1a	collagen type II, alpha-1a	0.018
thbs1	thrombospondin 1	0.018
ndr2	nodal-related 2	0.018
zgc:158603	zgc:158603	0.018
ints6	integrator complex subunit 6	0.017
frem3	Fras1 related extracellular matrix 3	0.017
lect1	leukocyte cell derived chemotaxin 1	0.017
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.017
nrarpa	notch-regulated ankyrin repeat protein a	0.017
boc	brother of CDO	0.017
LOC797832	similar to signal peptide, CUB domain, EGF-like 1	0.017
nanos3	nanos homolog 3	0.017
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.017
prkar1aa	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a	0.017
si:dkeyp-68f6.1	si:dkeyp-68f6.1	0.016
mapk1	mitogen-activated protein kinase 1	0.016
col4a5	collagen, type IV, alpha 5 (Alport syndrome)	0.016
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.016
scube2	signal peptide, CUB domain, EGF-like 2	0.016
bmp1a	bone morphogenetic protein 1a	0.016
LOC100359374	BCL-WAV	0.016
ap2a1	adaptor-related protein complex 2, alpha 1 subunit	0.016
atp6v1d	ATPase, H+ transporting, V1 subunit D and ATPase, H+ transporting, V1 subunit D	0.016
unc5db	unc-5 homolog Db (C. elegans)	0.016
mapk6	mitogen-activated protein kinase 6	0.016
ldb2b	LIM-domain binding factor 2b	0.016
f2r	coagulation factor II (thrombin) receptor	0.016
eve1	even-skipped-like1	0.016
znf711	zinc finger protein 711	0.016
nhsl1b	NHS-like 1b	0.016
efnb2a	ephrin B2a	0.015
cfl2l	cofilin 2, like	0.015
epb4.1l4	erythrocyte protein band 4.1-like 4	0.015
arl4ab	ADP-ribosylation factor-like 4ab	0.015
foxd3	forkhead box D3	0.015
rargb	retinoic acid receptor, gamma b	0.015
cdh17	cadherin 17, LI cadherin (liver-intestine)	0.015
zfyve26	zinc finger, FYVE domain containing 26	0.015
csnk1da	casein kinase 1, delta a	0.015
hoxb1a	homeo box B1a	0.015
esrra	estrogen-related receptor alpha	0.015
bmp7a	bone morphogenetic protein 7a	0.015
igfbp3	insulin-like growth factor binding protein 3	0.015
fbn2b	fibrillin 2b	0.015
egfl6	EGF-like-domain, multiple 6	0.015
oprm1	opioid receptor, mu 1	0.015
ext2	exostoses (multiple) 2	0.014
zgc:101598	zgc:101598	0.014
dharma	dharma	0.014
stk36	serine/threonine kinase 36 (fused homolog, Drosophila)	0.014
mcoln1	mucolipin 1	0.014
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.014
ndr1	nodal-related 1	0.014
wnt10b	wingless-type MMTV integration site family, member 10b	0.014	Zebrafish
gnl2	guanine nucleotide binding protein-like 2 (nucleolar)	0.014
vasa	vasa homolog	0.014
mapk7	mitogen-activated protein kinase 7	0.014
notch2	notch homolog 2	0.014
grhl2b	grainyhead-like 2b (Drosophila)	0.014
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.014
ephb4a	eph receptor B4a	0.014
dusp6	dual specificity phosphatase 6	0.013
marcksl1	MARCKS-like 1	0.013
igf2a	insulin-like growth factor 2a	0.013
celsr1b	cadherin EGF LAG seven-pass G-type receptor 1b	0.013	Mouse
ntn2	netrin 2	0.013
npnt	nephronectin	0.013
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.013	Mouse
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.013
gli2b	GLI-Kruppel family member GLI2b	0.013
gbx1	gastrulation brain homeobox 1	0.013
im:7162646	im:7162646	0.013
pgr	progesterone receptor	0.013
foxb1.1	forkhead box B1.1	0.013
kif7	kinesin family member 7	0.013
cpsf6	cleavage and polyadenylation specific factor 6	0.013
cobl	cordon-bleu homolog (mouse)	0.013
araf	v-raf murine sarcoma 3611 viral oncogene homolog	0.013
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.013
sox17	SRY-box containing gene 17	0.013
hoxb1b	homeo box B1b	0.013
ovol1	ovo-like 1 (Drosophila)	0.012
nrarpb	notch-regulated ankyrin repeat protein b	0.012
flr	fleer	0.012
alcamb	activated leukocyte cell adhesion molecule b	0.012
tbx15	T-box 15	0.012
nog3	noggin 3	0.012
extl3	exostoses (multiple)-like 3	0.012
hoxa13b	homeo box A13b	0.012
snf8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.012
pglyrp6	peptidoglycan recognition protein 6	0.012
pcdh18b	protocadherin 18b	0.012
angptl2	angiopoietin-like 2	0.012
si:ch1073-351m12.1	si:ch1073-351m12.1	0.012
LOC567452	G protein-coupled receptor kinase 5-like	0.012
hspg2	heparan sulfate proteoglycan 2	0.012
axin2	axin 2 (conductin, axil)	0.011
tph1b	tryptophan hydroxylase 1b	0.011
appl1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.011
ift52	intraflagellar transport protein 52	0.011
ryk	receptor-like tyrosine kinase	0.011
cxcl12a	chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)	0.011
htra1a	HtrA serine peptidase 1a	0.011
irx1b	iroquois homeobox protein 1, b	0.011
gyltl1b	glycosyltransferase-like 1b	0.011
crtap	cartilage associated protein	0.011
kdrl	kinase insert domain receptor like	0.011
fbxl14b	F-box and leucine-rich repeat protein 14b	0.011
pdlim3b	PDZ and LIM domain 3b	0.011
ptk2.1	protein tyrosine kinase 2a	0.011
dag1	dystroglycan 1	0.011
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.011
tpbgl	trophoblast glycoprotein-like	0.011
metrn	meteorin, glial cell differentiation regulator	0.011
bmp2a	bone morphogenetic protein 2a	0.011
pcdh8	protocadherin 8	0.011
tob1a	transducer of ERBB2, 1a	0.011
sept6	septin 6	0.011
ier2	immediate early response 2	0.010
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.010
yaf2	YY1 associated factor 2	0.010
upf1	upf1 regulator of nonsense transcripts homolog (yeast)	0.010
clstn2	calsyntenin 2	0.010
nkx3.2	NK3 homeobox 2	0.010
fgfr4	fibroblast growth factor receptor 4	0.010
chst11	carbohydrate (chondroitin 4) sulfotransferase 11	0.010
jag1b	jagged 1b	0.010
tuba8l3	tubulin, alpha 8 like 3	0.010
ndst2a	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2a	0.010
ggnbp2	gametogenetin binding protein 2	0.010
lfng	lunatic fringe homolog	0.010
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.010
fzd6	frizzled homolog 6 (Drosophila)	0.010
crabp2b	cellular retinoic acid binding protein 2, b	0.010
celsr1a	cadherin EGF LAG seven-pass G-type receptor 1a	0.010	Mouse
has2	hyaluronan synthase 2	0.010