The network for 'chromosome organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

chromosome organization

A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.

Drosophila melanogaster
Name Description Probability Func Analog Organism
polo CG12306 gene product from transcript CG12306-RA 1.000
asp abnormal spindle 1.000
Dref DNA replication-related element factor 1.000
Mcm10 Sensitized chromosome inheritance modifier 19 0.999
mod(mdg4) modifier of mdg4 0.999
brm brahma 0.999
egg eggless 0.998
Sir2 CG5216 gene product from transcript CG5216-RA 0.998
Fs(2)Ket Female sterile (2) Ketel 0.998
RfC4 Replication factor C subunit 4 0.997
Rpd3 CG7471 gene product from transcript CG7471-RA 0.997
E(z) Enhancer of zeste 0.995
Iswi Imitation SWI 0.995
p53 CG33336 gene product from transcript CG33336-RB 0.994
Scm Sex comb on midleg 0.994
mus209 mutagen-sensitive 209 0.993
Su(var)2-HP2 CG12864 gene product from transcript CG12864-RB 0.993
BubR1 Bub1-related kinase 0.992
Cp190 Centrosomal protein 190kD 0.992
Rca1 Regulator of cyclin A1 0.991
Su(var)2-10 Suppressor of variegation 2-10 0.990
gwl greatwall 0.990
dik diskette 0.987
nbs CG6754 gene product from transcript CG6754-RC 0.984
CycA Cyclin A 0.983
Cenp-C CG31258 gene product from transcript CG31258-RA 0.981
cav caravaggio 0.981
Su(var)205 Suppressor of variegation 205 0.980
Orc2 Origin recognition complex subunit 2 0.979
pr-set7 CG3307 gene product from transcript CG3307-RC 0.977
CTCF CG8591 gene product from transcript CG8591-RA 0.975
woc without children 0.971
SMC2 CG10212 gene product from transcript CG10212-RA 0.969
SMC1 CG6057 gene product from transcript CG6057-RA 0.969
spn-E spindle E 0.966
Snr1 Snf5-related 1 0.963
Dhc64C Dynein heavy chain 64C 0.959
pav pavarotti 0.959
Hsp83 Heat shock protein 83 0.958
CG3363 CG3363 gene product from transcript CG3363-RB 0.958
smt3 CG4494 gene product from transcript CG4494-RA 0.958
pie pineapple eye 0.956
CSN4 COP9 complex homolog subunit 4 0.956
lwr lesswright 0.953
Pc Polycomb 0.952
CG9772 CG9772 gene product from transcript CG9772-RB 0.950
mrn marionette 0.950
ball ballchen 0.950
Rbf Retinoblastoma-family protein 0.949
Ino80 CG31212 gene product from transcript CG31212-RA 0.947
Ndc80 CG9938 gene product from transcript CG9938-RA 0.945
cmet CENP-meta 0.944
Incenp Inner centromere protein 0.940
Chrac-14 CG13399 gene product from transcript CG13399-RA 0.938
Src64B Src oncogene at 64B 0.935
rin rasputin 0.933
XNP CG4548 gene product from transcript CG4548-RA 0.933
tum tumbleweed 0.933
vih vihar 0.930
sti sticky 0.926
Klp61F Kinesin-like protein at 61F 0.924
Rheb CG1081 gene product from transcript CG1081-RA 0.924
Akt1 CG4006 gene product from transcript CG4006-RA 0.911
not non-stop 0.910
tefu telomere fusion 0.908
Rga Regena 0.901
slmb supernumerary limbs 0.897
Spc25 CG7242 gene product from transcript CG7242-RA 0.896
CycB Cyclin B 0.894
ida imaginal discs arrested 0.889
spn-B spindle B 0.889
jumu jumeau 0.888
l(1)dd4 lethal (1) discs degenerate 4 0.885
Caf1-180 CG12109 gene product from transcript CG12109-RB 0.883
cg combgap 0.877
Cap-G CG34438 gene product from transcript CG34438-RF 0.876
Rae1 CG9862 gene product from transcript CG9862-RA 0.874
mars CG17064 gene product from transcript CG17064-RB 0.873
Hsf Heat shock factor 0.867
dup double parked 0.867
Nipped-A CG33554 gene product from transcript CG33554-RE 0.867
Klp10A CG1453 gene product from transcript CG1453-RA 0.865
pim pimples 0.856
Top2 Topoisomerase 2 0.853
rad50 CG6339 gene product from transcript CG6339-RD 0.851
mei-41 meiotic 41 0.851
dap dacapo 0.849
fzy fizzy 0.844
AGO2 Argonaute 2 0.840
pygo pygopus 0.836
SuUR Suppressor of Under-Replication 0.835
ci cubitus interruptus 0.834
Hsp68 Heat shock protein 68 0.834
Hsp70Aa Heat-shock-protein-70Aa 0.832
Su(var)3-3 Suppressor of variegation 3-3 0.818
dpa disc proliferation abnormal 0.817
CycE Cyclin E 0.817
esc extra sexcombs 0.817
rpr reaper 0.815
BRWD3 CG31132 gene product from transcript CG31132-RA 0.813
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
zyg-9 Protein ZYG-9 0.855
bub-1 Protein BUB-1 0.824
cul-2 Protein CUL-2 0.724
ima-2 Protein IMA-2 0.679
npp-19 Protein NPP-19 0.670
his-5 Protein HIS-5 0.652
air-2 Protein AIR-2 0.642
F33E11.3 Protein F33E11.3 0.630
his-16 Protein HIS-16 0.622
dcr-1 Protein DCR-1 0.603
syx-4 Protein SYX-4 0.583
ndc-80 Protein NDC-80 0.558
rfc-4 Protein RFC-4 0.557
CELE_F19F10.9 Protein F19F10.9 0.553
C01H6.9 Protein C01H6.9 0.550
hda-1 Protein HDA-1 0.545
mcm-7 Protein MCM-7 0.530
his-31 Protein HIS-31 0.518
lex-1 Protein LEX-1 0.500
sdc-1 Protein SDC-1 0.485
his-1 Protein HIS-1 0.480
rnr-1 Protein RNR-1 0.480
F33H2.3 Protein F33H2.3 0.479
bmk-1 Protein BMK-1 0.478
hcp-3 Protein HCP-3 0.467
klp-18 Protein KLP-18 0.453
sas-5 Protein SAS-5 0.449
mcm-3 Protein MCM-3 0.448
ZK328.4 Protein ZK328.4 0.444
B0336.3 Protein B0336.3 0.441
iff-1 Protein IFF-1 0.440
bar-1 Protein BAR-1 0.426
htz-1 Protein HTZ-1 0.411
crn-1 Protein CRN-1 0.407
D1081.8 Protein D1081.8 0.405
vrk-1 Protein VRK-1 0.398
wrm-1 Protein WRM-1 0.397
trr-1 Protein TRR-1 0.396
ucr-2.3 Protein UCR-2.3 0.395
rpa-1 Protein RPA-1 0.379
D2096.11 Protein D2096.11 0.378
lin-53 Protein LIN-53 0.374
ttm-4 Protein TTM-4 0.373
B0035.1 Protein B0035.1 0.357
rpn-1 Protein RPN-1 0.355
F25H5.5 Protein F25H5.5 0.354
ung-1 Protein UNG-1 0.352
mac-1 Protein MAC-1 0.351
smc-3 Protein SMC-3 0.350
baf-1 Protein BAF-1 0.346
mix-1 Protein MIX-1 0.338
F33H1.4 Protein F33H1.4 0.336
mcm-5 Protein MCM-5 0.336
pha-4 Protein PHA-4 0.334
nasp-1 Protein NASP-1 0.333
acs-4 Protein ACS-4 0.333
sas-4 Protein SAS-4 0.332
srgp-1 Protein SRGP-1 0.332
kle-2 Protein KLE-2 0.324
brc-1 Protein BRC-1 0.324
mcm-2 Protein MCM-2 0.321
csc-1 Protein CSC-1 0.318
rod-1 Protein ROD-1 0.314
rha-1 Protein RHA-1 0.306
ama-1 Protein AMA-1 0.306
his-42 Protein HIS-42 0.306
lin-61 Protein LIN-61 0.304
szy-20 Protein SZY-20 0.302
efl-1 Protein EFL-1 0.300
hil-3 Protein HIL-3 0.300
his-4 Protein HIS-4 0.297
R11A8.7 Protein R11A8.7 0.291
his-29 Protein HIS-29 0.290
hcp-2 Protein HCP-2 0.283
lin-35 Protein LIN-35 0.281
CELE_B0238.11 Protein B0238.11 0.281
knl-1 Protein KNL-1 0.277
CELE_C56A3.8 Protein C56A3.8 0.275
tra-4 Protein TRA-4 0.274
usp-46 Protein USP-46 0.273
aipl-1 Protein AIPL-1 0.268
dpl-1 Protein DPL-1 0.268
rde-2 Protein RDE-2 0.267
rba-1 Protein RBA-1 0.267
B0412.3 Protein B0412.3 0.264
kbp-5 Protein KBP-5 0.261
rnr-2 Protein RNR-2 0.259
his-9 Protein HIS-9 0.258
isw-1 Protein ISW-1 0.253
tag-135 Protein TAG-135 0.247
CELE_K08F4.1 Protein K08F4.1 0.242
C05D11.7 Protein C05D11.7 0.240
mig-32 Protein MIG-32 0.237
sas-6 Protein SAS-6 0.237
aspm-1 Protein ASPM-1 0.237
unc-85 Protein UNC-85 0.234
lin-5 Protein LIN-5 0.233
T02G5.12 Protein T02G5.12 0.233
his-64 Protein HIS-64 0.231
brf-1 Protein BRF-1 0.226
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Danio rerio
Name Description Probability Func Analog Organism
pcna proliferating cell nuclear antigen 0.997
suv39h1b suppressor of variegation 3-9 homolog 1b 0.841
nasp nuclear autoantigenic sperm protein (histone-binding) 0.838
nanos3 nanos homolog 3 0.836
spry4 sprouty (Drosophila) homolog 4 0.616
ncapd2 non-SMC condensin I complex, subunit D2 0.532
gro2 groucho 2 0.528
smc3 structural maintenance of chromosomes 3 0.495
hp1bp3 heterochromatin protein 1, binding protein 3 0.472
ncor1 nuclear receptor co-repressor 1 0.459
smc4 structural maintenance of chromosomes 4 0.455
her6 hairy-related 6 0.453
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.448
ccnb1 cyclin B1 0.432
kdm5c lysine (K)-specific demethylase 5C 0.431
fen1 flap structure-specific endonuclease 1 0.407
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.406
ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.395
brca2 breast cancer 2, early onset 0.362
ezh2 enhancer of zeste homolog 2 (Drosophila) 0.342
hoxa11b homeo box A11b 0.319
setdb1a SET domain, bifurcated 1a 0.301
osr1 odd-skipped related 1 (Drosophila) 0.286
ep300b E1A binding protein p300 b 0.278
ywhaba tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a 0.256
pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.253
smyd2a SET and MYND domain containing 2a 0.250
supt5h suppressor of Ty 5 homolog (S. cerevisiae) 0.245
mos v-mos Moloney murine sarcoma viral oncogene homolog 0.241
anp32a acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.223
setdb1b SET domain, bifurcated 1b 0.222
suv39h1a suppressor of variegation 3-9 homolog 1a 0.220
ube2i ubiquitin-conjugating enzyme E2I 0.205
rbb4l retinoblastoma binding protein 4, like 0.204
tipin timeless interacting protein 0.203
ube2i2 ubiquitin-conjugating enzyme E2I2 0.201
brd3a bromodomain containing 3a 0.196
slc2a10 solute carrier family 2 (facilitated glucose transporter), member 10 0.185
rpa1 replication protein A1 0.181
sass6 spindle assembly 6 homolog (C. elegans) 0.179
atad5a ATPase family, AAA domain containing 5a 0.178
rcc2 regulator of chromosome condensation 2 0.177
pbrm1l polybromo 1, like 0.177
ccna2 cyclin A2 0.176
ncaph non-SMC condensin I complex, subunit H 0.171
fancl Fanconi anemia, complementation group L 0.159
znf703 zinc finger protein 703 0.159
ssrp1a structure specific recognition protein 1a 0.159
setd8b SET domain containing (lysine methyltransferase) 8b 0.158
hoxd4a homeo box D4a 0.157
rbb4 retinoblastoma binding protein 4 0.157
pknox1.2 pbx/knotted 1 homeobox 1.2 0.152
smarcd1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0.148
mlh1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) 0.146
prps1b phosphoribosyl pyrophosphate synthetase 1B 0.145
nap1l1 nucleosome assembly protein 1, like 1 0.145
ehmt2 euchromatic histone-lysine N-methyltransferase 2 0.145
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.144
sirt2 sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) 0.142
fbl fibrillarin 0.139
rrm1 ribonucleotide reductase M1 polypeptide 0.138
ptena phosphatase and tensin homolog A 0.136
xpc xeroderma pigmentosum, complementation group C 0.134
gins2 GINS complex subunit 2 0.132
zff9 zinc finger protein 9 0.130
hat1 histone acetyltransferase 1 0.130
ctbp1 C-terminal binding protein 1 0.129
mycl1a v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) a 0.129
smc2 structural maintenance of chromosomes 2 0.128
mll4b myeloid/lymphoid or mixed-lineage leukemia 4b 0.126
melk maternal embryonic leucine zipper kinase 0.126
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.124
slc7a6os solute carrier family 7, member 6 opposite strand 0.123
ehmt1a euchromatic histone-lysine N-methyltransferase 1a 0.122
morf4l1 mortality factor 4 like 1 0.122
hoxc9a homeo box C9a 0.122
twist1a twist1a 0.121
setd2 SET domain containing 2 0.121
org oogenesis-related gene 0.120
prdm2b PR domain containing 2, with ZNF domain b 0.120
gle1 GLE1 RNA export mediator homolog (yeast) 0.118
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.117
chtf18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 0.117
hoxa9a homeo box A9a 0.114
wu:fi04f09 wu:fi04f09 0.113
ccnd1 cyclin D1 0.113
zgc:103670 zgc:103670 0.112
wdr76 WD repeat domain 76 0.111
cbx5 chromobox homolog 5 (HP1 alpha homolog, Drosophila) 0.110
zgc:174506 zgc:174506 0.109
msh6 mutS homolog 6 (E. coli) 0.108
zgc:101661 zgc:101661 0.107
prkrir protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 0.103
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.102
mcrs1 microspherule protein 1 0.101
tal1 T-cell acute lymphocytic leukemia 1 0.101
prmt5 protein arginine methyltransferase 5 0.100
pak2b p21 (CDKN1A)-activated kinase 2b 0.100
zgc:110113 zgc:110113 0.100
im:7136185 im:7136185 0.099
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Actb actin, beta 0.233
Phf12 PHD finger protein 12 0.226
Mcm7 minichromosome maintenance complex component 7 0.223
Top2a topoisomerase (DNA) II alpha 0.187
Ube2i ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.163
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.142
Timeless timeless homolog (Drosophila) 0.140
Parp1 poly (ADP-ribose) polymerase 1 0.112
Casp2 caspase 2 0.110
Stip1 stress-induced phosphoprotein 1 0.097
Bat1 HLA-B associated transcript 1 0.094
Zfp91 zinc finger protein 91 0.094
Dcaf15 DDB1 and CUL4 associated factor 15 0.092
Dhx30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.086
Falz fetal Alzheimer antigen 0.085
Mcm5 minichromosome maintenance complex component 5 0.082
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.081
Lbr lamin B receptor 0.079
Srrm2 serine/arginine repetitive matrix 2 0.077
Klf9 Kruppel-like factor 9 0.077
Foxm1 forkhead box M1 0.076
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.075
Mybl2 myeloblastosis oncogene-like 2 0.074
Traf4af1 TRAF4 associated factor 1 0.070
Hspa8 heat shock protein 8 0.070
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.070
Sf3b3 splicing factor 3b, subunit 3 0.067
Trim28 tripartite motif-containing 28 0.060
Ehmt2 euchromatic histone lysine N-methyltransferase 2 0.059
Kif18b kinesin family member 18B 0.057
Med1 mediator complex subunit 1 0.057
Map2k7 mitogen activated protein kinase kinase 7 0.057
Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 0.055
Iqgap1 IQ motif containing GTPase activating protein 1 0.053
Ccnb1 cyclin B1 0.053
Kif22 kinesin family member 22 0.052
Tpm3 tropomyosin 3, gamma 0.050
Eif4a1 eukaryotic translation initiation factor 4A, isoform 1 0.048
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.048
Numa1 nuclear mitotic apparatus protein 1 0.046
Prc1 protein regulator of cytokinesis 1 0.044
Arih2 ariadne homolog 2 (Drosophila) 0.043
Pttg1 pituitary tumor-transforming 1 0.043
Lsm14a LSM14A, SCD6 homolog A (S. cerevisiae) 0.043
Itgb1 integrin, beta 1 0.042
Ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.042
Cggbp1 CGG triplet repeat binding protein 1 0.041
Troap trophinin associated protein 0.040
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.039
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.039
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.039
Usp7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.038
Cstf1 cleavage stimulation factor, 3' pre-RNA, subunit 1 0.037
Racgap1 Rac GTPase-activating protein 1 0.036
Tubb5 tubulin, beta 5 0.036
Acin1 apoptotic chromatin condensation inducer 1 0.035
Ppp2r2a protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform 0.035
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.035
Set SET nuclear oncogene 0.034
Cenpt centromere protein T 0.034
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.034
Rbbp7 retinoblastoma binding protein 7 0.033
Cdc42 cell division cycle 42 (GTP binding protein) 0.033
Uba1 ubiquitin-like modifier activating enzyme 1 0.033
Arid4a AT rich interactive domain 4A (Rbp1 like) 0.032
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.032
Bud13 BUD13 homolog (S. cerevisiae) 0.032
Ube2c ubiquitin-conjugating enzyme E2C 0.032
Supt16h suppressor of Ty 16 homolog (S. cerevisiae) 0.032
Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform 0.031
Eef2 eukaryotic translation elongation factor 2 0.031
Slc23a3 solute carrier family 23 (nucleobase transporters), member 3 0.031
Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.031
Axin1 axin 1 0.031
Socs5 suppressor of cytokine signaling 5 0.030
Rbm10 RNA binding motif protein 10 0.030
Ufd1l ubiquitin fusion degradation 1 like (yeast) 0.030
Nup205 nucleoporin 205 0.030
Daxx death-domain associated protein 0.030
Klhl7 kelch-like 7 (Drosophila) 0.030
Fkbp4 FK506 binding protein 4 0.030
Pou2f2 POU class 2 homeobox 2 0.030
Cd82 Cd82 molecule 0.030
Bbx bobby sox homolog (Drosophila) 0.030
Hspd1 heat shock protein 1 (chaperonin) 0.030
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.030
Mettl9 methyltransferase like 9 0.029
Setd6 SET domain containing 6 0.029
Wdr26 WD repeat domain 26 0.029
Mcrs1 microspherule protein 1 0.029
Hsph1 heat shock 105/110 protein 1 0.028
Hnrnpr heterogeneous nuclear ribonucleoprotein R 0.028
Hspb1 heat shock protein 1 0.028
Tnrc6b trinucleotide repeat containing 6B 0.028
Cdk1 cyclin-dependent kinase 1 0.028
Kif4 kinesin family member 4 0.028
Sf3b2 splicing factor 3b, subunit 2 0.028
Nsfl1c NSFL1 (p97) cofactor (p47) 0.027
Asna1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 0.027
Eif1ay eukaryotic translation initiation factor 1A, Y-linked 0.027
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism