The network for 'negative regulation of gliogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of gliogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.

Homo sapiens
Name Description Probability Func Analog Organism
BTRC beta-transducin repeat containing 1.000
SMAD7 SMAD family member 7 0.999
SMAD4 SMAD family member 4 0.997
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.992
POU3F2 POU class 3 homeobox 2 0.990
PAX3 paired box 3 0.987
YAP1 Yes-associated protein 1 0.982
SMAD3 SMAD family member 3 0.981
SCHIP1 schwannomin interacting protein 1 0.934
CUL1 cullin 1 0.920
FBXW11 F-box and WD repeat domain containing 11 0.904
JAG1 jagged 1 0.880
ZFYVE9 zinc finger, FYVE domain containing 9 0.818
AMOTL1 angiomotin like 1 0.814
BMP7 bone morphogenetic protein 7 0.797
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.775
CDC14B CDC14 cell division cycle 14 homolog B (S. cerevisiae) 0.727
SKIL SKI-like oncogene 0.712
CXXC5 CXXC finger protein 5 0.702
POU5F1 POU class 5 homeobox 1 0.665
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.649
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.633
FGF1 fibroblast growth factor 1 (acidic) 0.622
NOTCH3 notch 3 0.617
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.543
ALB albumin 0.521
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.516
TNRC6A trinucleotide repeat containing 6A 0.505
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.467
SMAD1 SMAD family member 1 0.449
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.445
MEOX2 mesenchyme homeobox 2 0.421
AMOTL2 angiomotin like 2 0.418
MAX MYC associated factor X 0.413
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.390
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.384
FOXD3 forkhead box D3 0.368
SNAI1 snail homolog 1 (Drosophila) 0.332
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.326
SKP1 S-phase kinase-associated protein 1 0.314
MARCKSL1 MARCKS-like 1 0.299
TCF4 transcription factor 4 0.267
CDC34 cell division cycle 34 homolog (S. cerevisiae) 0.255
OLIG2 oligodendrocyte lineage transcription factor 2 0.249
FGFR2 fibroblast growth factor receptor 2 0.246
MAML1 mastermind-like 1 (Drosophila) 0.234
GLIS2 GLIS family zinc finger 2 0.234
XIAP X-linked inhibitor of apoptosis 0.230
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.227
LATS1 LATS, large tumor suppressor, homolog 1 (Drosophila) 0.208
SALL2 sal-like 2 (Drosophila) 0.204
SMAD5 SMAD family member 5 0.203
AMOT angiomotin 0.203
HIST1H3B histone cluster 1, H3b 0.197
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.186
STK38L serine/threonine kinase 38 like 0.185
EIF2C2 eukaryotic translation initiation factor 2C, 2 0.178
AXIN1 axin 1 0.173
HEY1 hairy/enhancer-of-split related with YRPW motif 1 0.166
BMP2 bone morphogenetic protein 2 0.164
SOX9 SRY (sex determining region Y)-box 9 0.157
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.148
PSEN1 presenilin 1 0.148
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.146
WEE1 WEE1 homolog (S. pombe) 0.144
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.139
NCOR1 nuclear receptor corepressor 1 0.139
F3 coagulation factor III (thromboplastin, tissue factor) 0.136
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.135
TAL1 T-cell acute lymphocytic leukemia 1 0.132
MYOD1 myogenic differentiation 1 0.132
FBLN1 fibulin 1 0.131
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.123
FOXG1 forkhead box G1 0.121
MSX1 msh homeobox 1 0.115
CDH5 cadherin 5, type 2 (vascular endothelium) 0.111
SKI v-ski sarcoma viral oncogene homolog (avian) 0.110
FGA fibrinogen alpha chain 0.110
FBXW7 F-box and WD repeat domain containing 7 0.109
PLG plasminogen 0.109
SOX11 SRY (sex determining region Y)-box 11 0.109
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.108
SLC9A3R2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.106
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.101
EEF2K eukaryotic elongation factor-2 kinase 0.100
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.099
EIF2C1 eukaryotic translation initiation factor 2C, 1 0.098
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.094
GFAP glial fibrillary acidic protein 0.092
HIST1H4F histone cluster 1, H4f 0.092
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.087
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.087
APC adenomatous polyposis coli 0.086
DLL1 delta-like 1 (Drosophila) 0.085
SALL3 sal-like 3 (Drosophila) 0.082
TRIM9 tripartite motif containing 9 0.080
FERMT2 fermitin family member 2 0.079
ASCL1 achaete-scute complex homolog 1 (Drosophila) 0.079
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.078
INHBB inhibin, beta B 0.078
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
her4.2 hairy-related 4.2 0.956
ascl1a achaete-scute complex-like 1a (Drosophila) 0.799
dld deltaD 0.798
notch3 notch homolog 3 0.724
her12 hairy-related 12 0.718
dla deltaA 0.618
pcdh17 protocadherin 17 0.502
olig2 oligodendrocyte lineage transcription factor 2 0.448
lhx1a LIM homeobox 1a 0.418
ascl1b achaete-scute complex-like 1b (Drosophila) 0.405
foxp2 forkhead box P2 0.403
dmrta2 doublesex and mab-3 related transcription factor like family A2 0.394
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.391
dlb deltaB 0.376
dlx1a distal-less homeobox gene 1a 0.364
otx1b orthodenticle homolog 1b 0.360
otpb orthopedia homolog b 0.336
lfng lunatic fringe homolog 0.333
sox3 SRY-box containing gene 3 0.324
rspo3 R-spondin 3 homolog (Xenopus laevis) 0.309
barhl2 BarH-like 2 0.304
dbx1a developing brain homeobox 1a 0.283
efnb2a ephrin B2a 0.258
insm1b insulinoma-associated 1b 0.257
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.233
zic4 zic family member 4 0.221
dlc deltaC 0.220
osr1 odd-skipped related 1 (Drosophila) 0.219
insm1a insulinoma-associated 1a 0.192
olig4 oligodendrocyte transcription factor 4 0.187
pitx3 paired-like homeodomain transcription factor 3 0.180
sfrp5 secreted frizzled-related protein 5 0.159
her15.1 hairy and enhancer of split-related 15.1 0.159
tpbgl trophoblast glycoprotein-like 0.158
epha4a eph receptor A4a 0.157
fzd7a frizzled homolog 7a 0.151
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.139
cd99l2 CD99 antigen-like 2 0.137
pou5f1 POU domain, class 5, transcription factor 1 0.133
pax6a paired box gene 6a 0.130
sox21b SRY-box containing gene 21 b 0.127
sox2 SRY-box containing gene 2 0.117
emx2 empty spiracles homeobox 2 0.113
nog2 noggin 2 0.110
pvrl1b poliovirus receptor-related 1b 0.106
pax6b paired box gene 6b 0.106
vsx2 visual system homeobox 2 0.098
meis2.2 myeloid ecotropic viral integration site 2.2 0.098
fezf2 FEZ family zinc finger 2 0.097
nova2 neuro-oncological ventral antigen 2 0.097
gli3 GLI-Kruppel family member GLI3 0.095
neurod4 neurogenic differentiation 4 0.095
nf1b neurofibromin 1b 0.093
cnr1 cannabinoid receptor 1 0.093
arx aristaless related homeobox 0.093
bon bonnie and clyde 0.092
nadl1.2 neural adhesion molecule L1.2 0.091
olig3 oligodendrocyte transcription factor 3 0.089
pou3f1 POU class 3 homeobox 1 0.088
reln reelin 0.087
nf1a neurofibromin 1a 0.087
aplnrb apelin receptor b 0.086
zgc:110298 zgc:110298 0.084
msi1 musashi homolog 1 (Drosophila) 0.083
egr1 early growth response 1 0.082
cdkn1c cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.081
jag1a jagged 1a 0.080
dnmt8 DNA (cytosine-5-)-methyltransferase 8 0.080
cdh2 cadherin 2, neuronal 0.077
dact2 dapper homolog 2, antagonist of beta-catenin (xenopus) 0.077
nr4a3 nuclear receptor subfamily 4, group A, member 3 0.076
antxr1 anthrax toxin receptor 1 0.076
hnf1bb HNF1 homeobox Bb 0.076
jag2 jagged 2 0.076
dlx2b distal-less homeobox gene 2b 0.074
gbx1 gastrulation brain homeobox 1 0.071
zgc:113312 zgc:113312 0.071
lrrn1 leucine rich repeat neuronal 1 0.071
foxb1.2 forkhead box B1.2 0.070
sim1a single-minded homolog 1a (Drosophila) 0.069
rasl11b RAS-like, family 11, member B 0.068
sox19a SRY-box containing gene 19a 0.067
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.066
cnot6 CCR4-NOT transcription complex, subunit 6 0.066
sox17 SRY-box containing gene 17 0.065
cdx4 caudal type homeo box transcription factor 4 0.065
clstn1 calsyntenin 1 0.065
LOC100007758 novel protein similar to vertebrate SLIT and NTRK-like family, member 3 (SLITRK3) 0.064
nr2f2 nuclear receptor subfamily 2, group F, member 2 0.064
msxc muscle segment homeobox C 0.063
nr4a2b nuclear receptor subfamily 4, group A, member 2b 0.063
glra4a glycine receptor, alpha 4a 0.060
ptrfb polymerase I and transcript release factor b 0.060
siah1 seven in absentia homolog 1 (Drosophila) 0.058
otx2 orthodenticle homolog 2 0.057
mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.057
wisp1b WNT1 inducible signaling pathway protein 1b 0.057
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.055
celf1 cugbp, Elav-like family member 1 0.054
si:dkeyp-63d11.7 si:dkeyp-63d11.7 0.053
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Drosophila melanogaster
Name Description Probability Func Analog Organism
HLHm7 E(spl) region transcript m7 0.935
E(spl) Enhancer of split 0.906
HLHmgamma E(spl) region transcript mgamma 0.892
HLHmdelta E(spl) region transcript mdelta 0.397
HLHmbeta E(spl) region transcript mbeta 0.285
HLHm5 E(spl) region transcript m5 0.146
HLHm3 E(spl) region transcript m3 0.133
yki yorkie 0.133
ac achaete 0.126
sc scute 0.125
bnl branchless 0.093
malpha E(spl) region transcript malpha 0.064
klu klumpfuss 0.064
tkv thickveins 0.055
m2 E(spl) region transcript m2 0.045
dm diminutive 0.039
Mad Mothers against dpp 0.032
ato atonal 0.031
Moe Moesin 0.030
N Notch 0.027
ci cubitus interruptus 0.026
m4 E(spl) region transcript m4 0.022
kay kayak 0.017
fz2 frizzled 2 0.017
pasha partner of drosha 0.017
Akt1 CG4006 gene product from transcript CG4006-RA 0.016
nej nejire 0.016
CG5794 CG5794 gene product from transcript CG5794-RB 0.014
H Hairless 0.014
salm spalt major 0.013
wg wingless 0.013
ase asense 0.012
ft fat 0.011
Tollo CG6890 gene product from transcript CG6890-RA 0.011
Tsc1 CG6147 gene product from transcript CG6147-RA 0.011
ed echinoid 0.011
aop anterior open 0.010
drpr draper 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 0.998
Emx1 empty spiracles homolog 1 (Drosophila) 0.997
Sox9 SRY-box containing gene 9 0.994
Ctnnb1 catenin (cadherin associated protein), beta 1 0.992
Pax3 paired box gene 3 0.986
Shh sonic hedgehog 0.981
Isl1 ISL1 transcription factor, LIM/homeodomain 0.979
Fgfr1 fibroblast growth factor receptor 1 0.946
Bmp4 bone morphogenetic protein 4 0.924
Hes1 hairy and enhancer of split 1 (Drosophila) 0.910
Gli3 GLI-Kruppel family member GLI3 0.896
Otx2 orthodenticle homolog 2 (Drosophila) 0.885
Hand2 heart and neural crest derivatives expressed transcript 2 0.875
Prrx1 paired related homeobox 1 0.850
Tcfap2a transcription factor AP-2, alpha 0.847
Nf1 neurofibromatosis 1 0.845
Dlx1 distal-less homeobox 1 0.842
Foxc1 forkhead box C1 0.828
Pax6 paired box gene 6 0.822
Hand1 heart and neural crest derivatives expressed transcript 1 0.815
Eya1 eyes absent 1 homolog (Drosophila) 0.807
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.796
Msx1 homeobox, msh-like 1 0.785
Trp53 transformation related protein 53 0.774
Sox2 SRY-box containing gene 2 0.757
Id3 inhibitor of DNA binding 3 0.753
Fgf8 fibroblast growth factor 8 0.737
Ret ret proto-oncogene 0.735
Emx2 empty spiracles homolog 2 (Drosophila) 0.732
Apc adenomatosis polyposis coli 0.727
Id1 inhibitor of DNA binding 1 0.614
Meox2 mesenchyme homeobox 2 0.610
Dlx2 distal-less homeobox 2 0.560
Alx4 aristaless-like homeobox 4 0.523
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.504
Pitx2 paired-like homeodomain transcription factor 2 0.484
Ptch1 patched homolog 1 0.394
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.364
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.351
Pbx1 pre B-cell leukemia transcription factor 1 0.321
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.317
Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) 0.313
Acvr1 activin A receptor, type 1 0.312
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.302
Dcx doublecortin 0.294
Gsc goosecoid homeobox 0.292
Notch1 Notch gene homolog 1 (Drosophila) 0.289
Smo smoothened homolog (Drosophila) 0.281
Msx2 homeobox, msh-like 2 0.277
Dlx5 distal-less homeobox 5 0.277
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.272
Sox10 SRY-box containing gene 10 0.267
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.244
Smad6 MAD homolog 6 (Drosophila) 0.241
Sox4 SRY-box containing gene 4 0.240
Rb1 retinoblastoma 1 0.239
Bmpr1a bone morphogenetic protein receptor, type 1A 0.239
Sall3 sal-like 3 (Drosophila) 0.231
Tgfb2 transforming growth factor, beta 2 0.220
Lef1 lymphoid enhancer binding factor 1 0.216
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.213
Insm1 insulinoma-associated 1 0.198
Efnb2 ephrin B2 0.184
Tsc2 tuberous sclerosis 2 0.174
Dlx6 distal-less homeobox 6 0.169
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.168
Prrx2 paired related homeobox 2 0.156
Gli2 GLI-Kruppel family member GLI2 0.154
Dll1 delta-like 1 (Drosophila) 0.141
Lhx3 LIM homeobox protein 3 0.135
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.133
Pten phosphatase and tensin homolog 0.133
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.130
Col2a1 collagen, type II, alpha 1 0.129
Rara retinoic acid receptor, alpha 0.128
Hoxa2 homeobox A2 0.128
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.126
Sox1 SRY-box containing gene 1 0.125
Sox11 SRY-box containing gene 11 0.123
Gata4 GATA binding protein 4 0.121
Olig2 oligodendrocyte transcription factor 2 0.118
Chd7 chromodomain helicase DNA binding protein 7 0.115
Cckbr cholecystokinin B receptor 0.114
Trp63 transformation related protein 63 0.108
Tbx1 T-box 1 0.107
Emid2 EMI domain containing 2 0.101
Psen1 presenilin 1 0.101
Bmp7 bone morphogenetic protein 7 0.101
Nog noggin 0.095
Tbx3 T-box 3 0.095
Lmx1b LIM homeobox transcription factor 1 beta 0.093
Pou3f3 POU domain, class 3, transcription factor 3 0.092
Rxra retinoid X receptor alpha 0.088
She src homology 2 domain-containing transforming protein E 0.086
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.086
Foxg1 forkhead box G1 0.086
Rarb retinoic acid receptor, beta 0.084
Foxc2 forkhead box C2 0.082
Msi1 Musashi homolog 1(Drosophila) 0.080
Gbx2 gastrulation brain homeobox 2 0.078
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism