IMP
Process View
The network for 'epithelial tube branching involved in lung morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
epithelial tube branching involved in lung morphogenesis
The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 1.000 | |
| FGF1 | fibroblast growth factor 1 (acidic) | 1.000 | |
| FGF10 | fibroblast growth factor 10 | 1.000 | |
| TBX5 | T-box 5 | 0.999 | |
| FGFR1 | fibroblast growth factor receptor 1 | 0.999 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.997 | |
| FGF7 | fibroblast growth factor 7 | 0.988 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.979 | |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.956 | |
| POU5F1 | POU class 5 homeobox 1 | 0.938 | |
| DMD | dystrophin | 0.935 | |
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.889 | |
| UTRN | utrophin | 0.884 | |
| PAX8 | paired box 8 | 0.832 | |
| AR | androgen receptor | 0.816 | |
| FGFR3 | fibroblast growth factor receptor 3 | 0.773 | |
| FOXD3 | forkhead box D3 | 0.682 | |
| PFN1 | profilin 1 | 0.634 | |
| DTNA | dystrobrevin, alpha | 0.546 | |
| GATA4 | GATA binding protein 4 | 0.530 | |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.526 | |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.491 | |
| HOXA10 | homeobox A10 | 0.487 | |
| DDX47 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 | 0.440 | |
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.437 | |
| FGF3 | fibroblast growth factor 3 | 0.434 | |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.432 | |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.426 | |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.390 | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.370 | |
| BTRC | beta-transducin repeat containing | 0.335 | |
| CTGF | connective tissue growth factor | 0.323 | |
| PKP4 | plakophilin 4 | 0.281 | |
| IGSF21 | immunoglobin superfamily, member 21 | 0.275 | |
| FSTL1 | follistatin-like 1 | 0.270 | |
| SALL2 | sal-like 2 (Drosophila) | 0.239 | |
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.232 | |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.226 | |
| CD14 | CD14 molecule | 0.225 | |
| GLIS2 | GLIS family zinc finger 2 | 0.219 | |
| FGF4 | fibroblast growth factor 4 | 0.208 | |
| RTKN | rhotekin | 0.205 | |
| FGF2 | fibroblast growth factor 2 (basic) | 0.203 | |
| ONECUT1 | one cut homeobox 1 | 0.202 | |
| FOXA2 | forkhead box A2 | 0.195 | |
| HOXB5 | homeobox B5 | 0.193 | |
| WNT1 | wingless-type MMTV integration site family, member 1 | 0.182 | |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.178 | |
| BTBD10 | BTB (POZ) domain containing 10 | 0.176 | |
| FOXF2 | forkhead box F2 | 0.159 | |
| TGFB2 | transforming growth factor, beta 2 | 0.152 | |
| TCF4 | transcription factor 4 | 0.151 | |
| NOG | noggin | 0.150 | |
| JUP | junction plakoglobin | 0.150 | |
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.149 | |
| APC | adenomatous polyposis coli | 0.141 | |
| GSC | goosecoid homeobox | 0.116 | |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.114 | |
| HOXD1 | homeobox D1 | 0.107 | |
| FERMT2 | fermitin family member 2 | 0.106 | |
| PAX7 | paired box 7 | 0.095 | |
| HOXA1 | homeobox A1 | 0.094 | |
| HOXA7 | homeobox A7 | 0.093 | |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.092 | |
| EEA1 | early endosome antigen 1 | 0.085 | |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.085 | |
| ERBB2IP | erbb2 interacting protein | 0.084 | |
| DTNB | dystrobrevin, beta | 0.081 | |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.080 | |
| SOX1 | SRY (sex determining region Y)-box 1 | 0.080 | |
| FOXA1 | forkhead box A1 | 0.078 | |
| ALX4 | ALX homeobox 4 | 0.078 | |
| HNF1A | HNF1 homeobox A | 0.078 | |
| COL2A1 | collagen, type II, alpha 1 | 0.078 | |
| EMD | emerin | 0.075 | |
| SIX2 | SIX homeobox 2 | 0.075 | |
| TBX1 | T-box 1 | 0.074 | |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.073 | |
| C9orf25 | chromosome 9 open reading frame 25 | 0.073 | |
| GSK3B | glycogen synthase kinase 3 beta | 0.071 | |
| SALL1 | sal-like 1 (Drosophila) | 0.071 | |
| FOXL1 | forkhead box L1 | 0.071 | |
| VCL | vinculin | 0.070 | |
| FGF19 | fibroblast growth factor 19 | 0.070 | |
| UTF1 | undifferentiated embryonic cell transcription factor 1 | 0.070 | |
| BAG1 | BCL2-associated athanogene | 0.070 | |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | 0.069 | |
| HOXB13 | homeobox B13 | 0.069 | |
| PEBP4 | phosphatidylethanolamine-binding protein 4 | 0.067 | |
| MAP2 | microtubule-associated protein 2 | 0.067 | |
| FOXE1 | forkhead box E1 (thyroid transcription factor 2) | 0.066 | |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.065 | |
| SIM2 | single-minded homolog 2 (Drosophila) | 0.063 | |
| MNX1 | motor neuron and pancreas homeobox 1 | 0.062 | |
| WNT3 | wingless-type MMTV integration site family, member 3 | 0.061 | |
| EGLN1 | egl nine homolog 1 (C. elegans) | 0.061 | |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.060 | |
| PTF1A | pancreas specific transcription factor, 1a | 0.059 | |
| NKX2-1 | NK2 homeobox 1 | 0.057 | |
| SIX6 | SIX homeobox 6 | 0.056 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Foxc1 | forkhead box C1 | 1.000 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
| Shh | sonic hedgehog | 0.999 | |
| Pax2 | paired box gene 2 | 0.998 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.991 | |
| Bmp4 | bone morphogenetic protein 4 | 0.982 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.973 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.971 | |
| Fgf8 | fibroblast growth factor 8 | 0.956 | |
| Fgf10 | fibroblast growth factor 10 | 0.953 | |
| Pax8 | paired box gene 8 | 0.953 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.936 | |
| Tcf21 | transcription factor 21 | 0.921 | |
| Meox2 | mesenchyme homeobox 2 | 0.916 | |
| Pax3 | paired box gene 3 | 0.901 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.895 | |
| Chrd | chordin | 0.888 | |
| Sox2 | SRY-box containing gene 2 | 0.871 | |
| Sox9 | SRY-box containing gene 9 | 0.861 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.852 | |
| Foxc2 | forkhead box C2 | 0.803 | |
| Msx1 | homeobox, msh-like 1 | 0.800 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.782 | |
| Jag1 | jagged 1 | 0.772 | |
| Nkx2-1 | NK2 homeobox 1 | 0.727 | |
| Hoxa9 | homeobox A9 | 0.710 | |
| Hoxb6 | homeobox B6 | 0.683 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.678 | |
| Hoxa1 | homeobox A1 | 0.673 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.672 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.657 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.657 | |
| Hoxa11 | homeobox A11 | 0.645 | |
| Rarb | retinoic acid receptor, beta | 0.639 | |
| Hoxa5 | homeobox A5 | 0.633 | |
| Lhx1 | LIM homeobox protein 1 | 0.629 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.627 | |
| Efnb2 | ephrin B2 | 0.606 | |
| Hoxd11 | homeobox D11 | 0.601 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.588 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.586 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.584 | |
| Tbx1 | T-box 1 | 0.570 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.569 | |
| Nodal | nodal | 0.559 | |
| Tbx3 | T-box 3 | 0.539 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.529 | |
| Ret | ret proto-oncogene | 0.514 | |
| Hoxd9 | homeobox D9 | 0.498 | |
| Alx4 | aristaless-like homeobox 4 | 0.497 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.496 | |
| Ptch1 | patched homolog 1 | 0.496 | |
| Tbx2 | T-box 2 | 0.479 | |
| Fgf3 | fibroblast growth factor 3 | 0.471 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.470 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.462 | |
| Hoxc6 | homeobox C6 | 0.462 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.460 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.442 | |
| Prrx1 | paired related homeobox 1 | 0.411 | |
| Bmp7 | bone morphogenetic protein 7 | 0.404 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.391 | |
| Nog | noggin | 0.370 | |
| Hoxa10 | homeobox A10 | 0.356 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.353 | |
| Hoxd3 | homeobox D3 | 0.333 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.325 | |
| Hoxb5 | homeobox B5 | 0.317 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.312 | |
| Rarg | retinoic acid receptor, gamma | 0.311 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.307 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.305 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.297 | |
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.293 | |
| Hoxb3 | homeobox B3 | 0.292 | |
| Hoxa2 | homeobox A2 | 0.287 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.242 | |
| Ptk7 | PTK7 protein tyrosine kinase 7 | 0.241 | |
| Prrx2 | paired related homeobox 2 | 0.240 | |
| Gata4 | GATA binding protein 4 | 0.228 | |
| Gli1 | GLI-Kruppel family member GLI1 | 0.217 | |
| Hoxb9 | homeobox B9 | 0.208 | |
| Hoxd4 | homeobox D4 | 0.201 | |
| Hoxd8 | homeobox D8 | 0.200 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.199 | |
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.198 | |
| Sox7 | SRY-box containing gene 7 | 0.198 | |
| Gata6 | GATA binding protein 6 | 0.198 | |
| Dlx5 | distal-less homeobox 5 | 0.195 | |
| Hoxb2 | homeobox B2 | 0.186 | |
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.184 | |
| Wt1 | Wilms tumor 1 homolog | 0.184 | |
| Smo | smoothened homolog (Drosophila) | 0.182 | |
| T | brachyury | 0.181 | |
| Nf1 | neurofibromatosis 1 | 0.180 | |
| Pax6 | paired box gene 6 | 0.174 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.168 | |
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.166 | |
| Hoxa3 | homeobox A3 | 0.158 | |
| Sall4 | sal-like 4 (Drosophila) | 0.157 |