The network for 'positive regulation of amine transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of amine transport

Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Homo sapiens
Name Description Probability Func Analog Organism
DRD2 dopamine receptor D2 0.845
ARHGAP1 Rho GTPase activating protein 1 0.797
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.781
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.726
ADORA2A adenosine A2a receptor 0.574
HDAC6 histone deacetylase 6 0.523
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.518
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.516
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.479
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.311
FBXO7 F-box protein 7 0.130
RHOA ras homolog gene family, member A 0.127
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.106
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.085
RARA retinoic acid receptor, alpha 0.080
PARK2 parkinson protein 2, E3 ubiquitin protein ligase (parkin) 0.079
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.064
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.063
RHOC ras homolog gene family, member C 0.060
NECAB2 N-terminal EF-hand calcium binding protein 2 0.055
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.050
NCOA1 nuclear receptor coactivator 1 0.048
ADORA1 adenosine A1 receptor 0.043
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.043
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.042
NAMPT nicotinamide phosphoribosyltransferase 0.039
NBR1 neighbor of BRCA1 gene 1 0.036
PRKCA protein kinase C, alpha 0.035
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.029
MAST1 microtubule associated serine/threonine kinase 1 0.029
KCNJ5 potassium inwardly-rectifying channel, subfamily J, member 5 0.028
EZR ezrin 0.024
RIMS1 regulating synaptic membrane exocytosis 1 0.024
VAMP3 vesicle-associated membrane protein 3 (cellubrevin) 0.024
CYLD cylindromatosis (turban tumor syndrome) 0.024
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.024
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.022
NSF N-ethylmaleimide-sensitive factor 0.022
CYTH2 cytohesin 2 0.021
NCOA2 nuclear receptor coactivator 2 0.020
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.019
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.019
RPH3A rabphilin 3A homolog (mouse) 0.019
RIMS2 regulating synaptic membrane exocytosis 2 0.019
JUP junction plakoglobin 0.018
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.018
SIRT2 sirtuin 2 0.018
PICK1 protein interacting with PRKCA 1 0.017
PPP1R12C protein phosphatase 1, regulatory (inhibitor) subunit 12C 0.017
TMF1 TATA element modulatory factor 1 0.017
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.016
CALCOCO1 calcium binding and coiled-coil domain 1 0.016
KLF5 Kruppel-like factor 5 (intestinal) 0.016
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 0.016
SLC5A5 solute carrier family 5 (sodium iodide symporter), member 5 0.015
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.015
NCS1 neuronal calcium sensor 1 0.015
BGLAP bone gamma-carboxyglutamate (gla) protein 0.014
PPT1 palmitoyl-protein thioesterase 1 0.014
CNR1 cannabinoid receptor 1 (brain) 0.014
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.014
FAM190B family with sequence similarity 190, member B 0.014
TWF2 twinfilin, actin-binding protein, homolog 2 (Drosophila) 0.013
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.013
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 0.013
STX1A syntaxin 1A (brain) 0.013
DLG4 discs, large homolog 4 (Drosophila) 0.013
DIAPH1 diaphanous homolog 1 (Drosophila) 0.013
AVPR1B arginine vasopressin receptor 1B 0.013
KAT2B K(lysine) acetyltransferase 2B 0.012
KANK2 KN motif and ankyrin repeat domains 2 0.012
POLH polymerase (DNA directed), eta 0.012
PLEKHO1 pleckstrin homology domain containing, family O member 1 0.012
COL20A1 collagen, type XX, alpha 1 0.012
ZFAND5 zinc finger, AN1-type domain 5 0.012
CREBBP CREB binding protein 0.012
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.012
WDTC1 WD and tetratricopeptide repeats 1 0.011
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.011
SEZ6L seizure related 6 homolog (mouse)-like 0.011
ADD1 adducin 1 (alpha) 0.011
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.011
CD4 CD4 molecule 0.011
BBS10 Bardet-Biedl syndrome 10 0.011
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.011
IGF1R insulin-like growth factor 1 receptor 0.011
TBXA2R thromboxane A2 receptor 0.011
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.011
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.011
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.011
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.010
GNAS GNAS complex locus 0.010
SLC22A14 solute carrier family 22, member 14 0.010
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.010
TAGLN2 transgelin 2 0.010
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.010
TOLLIP toll interacting protein 0.010
GRIA4 glutamate receptor, ionotrophic, AMPA 4 0.010
DIO3 deiodinase, iodothyronine, type III 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
itr-1 Protein ITR-1 0.062
unc-10 Protein UNC-10 0.045
egl-15 Protein EGL-15 0.027
apg-1 Protein APG-1 0.019
pkg-1 Protein PKG-1 0.019
goa-1 Protein GOA-1 0.017
gar-3 Protein GAR-3 0.014
stim-1 Protein STIM-1 0.013
CELE_Y53F4B.5 Protein Y53F4B.5 0.013
CELE_K08E7.8 Protein K08E7.8 0.013
egl-36 Protein EGL-36 0.013
grk-2 Protein GRK-2 0.013
let-23 Protein LET-23 0.012
gpb-1 Protein GPB-1 0.012
unc-38 Protein UNC-38 0.012
slo-2 Protein SLO-2 0.011
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.999
Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 0.905
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 0.821
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.486
Drd2 dopamine receptor D2 0.381
Gabbr2 gamma-aminobutyric acid (GABA) B receptor, 2 0.269
Unc79 unc-79 homolog (C. elegans) 0.252
Rac1 RAS-related C3 botulinum substrate 1 0.194
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.182
Dlg4 discs, large homolog 4 (Drosophila) 0.168
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.160
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.157
Nos1 nitric oxide synthase 1, neuronal 0.109
Grik3 glutamate receptor, ionotropic, kainate 3 0.092
Chrna9 cholinergic receptor, nicotinic, alpha polypeptide 9 0.076
P2rx3 purinergic receptor P2X, ligand-gated ion channel, 3 0.058
Gjc2 gap junction protein, gamma 2 0.054
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.048
Ache acetylcholinesterase 0.044
Ypel3 yippee-like 3 (Drosophila) 0.043
Nxnl2 nucleoredoxin-like 2 0.041
Thra thyroid hormone receptor alpha 0.041
Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) 0.038
Dcx doublecortin 0.038
Has1 hyaluronan synthase1 0.037
Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 0.035
Chrna10 cholinergic receptor, nicotinic, alpha polypeptide 10 0.035
Epas1 endothelial PAS domain protein 1 0.034
Smyd1 SET and MYND domain containing 1 0.032
Drd1a dopamine receptor D1A 0.030
Opn1sw opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) 0.030
Grm1 glutamate receptor, metabotropic 1 0.029
Tpo thyroid peroxidase 0.028
Htr3a 5-hydroxytryptamine (serotonin) receptor 3A 0.027
Spp2 secreted phosphoprotein 2 0.026
P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.025
Plcb1 phospholipase C, beta 1 0.024
Nat8 N-acetyltransferase 8 (GCN5-related, putative) 0.022
Trpm5 transient receptor potential cation channel, subfamily M, member 5 0.022
Rapsn receptor-associated protein of the synapse 0.020
Map3k2 mitogen-activated protein kinase kinase kinase 2 0.020
Kcns2 K+ voltage-gated channel, subfamily S, 2 0.019
Myog myogenin 0.019
Lcn8 lipocalin 8 0.017
Ncam2 neural cell adhesion molecule 2 0.017
Smtn smoothelin 0.017
Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit 0.017
Ccl17 chemokine (C-C motif) ligand 17 0.017
Musk muscle, skeletal, receptor tyrosine kinase 0.017
Tcf7l2 transcription factor 7-like 2, T-cell specific, HMG-box 0.017
Chrnb3 cholinergic receptor, nicotinic, beta polypeptide 3 0.017
Itpr1 inositol 1,4,5-trisphosphate receptor 1 0.017
Grpr gastrin releasing peptide receptor 0.016
Gckr glucokinase regulatory protein 0.016
Plxna1 plexin A1 0.016
Ccr8 chemokine (C-C motif) receptor 8 0.016
Gjc3 gap junction protein, gamma 3 0.016
Prkch protein kinase C, eta 0.015
Wnt6 wingless-related MMTV integration site 6 0.015
Apln apelin 0.015
Gal galanin 0.015
Stk32b serine/threonine kinase 32B 0.015
Kcnk4 potassium channel, subfamily K, member 4 0.015
Pde1b phosphodiesterase 1B, Ca2+-calmodulin dependent 0.014
Phf1 PHD finger protein 1 0.014
St6galnac3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.014
Spry4 sprouty homolog 4 (Drosophila) 0.014
Slc22a13 solute carrier family 22 (organic cation transporter), member 13 0.014
Ptgir prostaglandin I receptor (IP) 0.014
Dpysl2 dihydropyrimidinase-like 2 0.014
Gfpt2 glutamine fructose-6-phosphate transaminase 2 0.014
Sphk1 sphingosine kinase 1 0.014
Mip major intrinsic protein of eye lens fiber 0.014
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.013
Tmed8 transmembrane emp24 domain containing 8 0.013
Dbh dopamine beta hydroxylase 0.013
Mybph myosin binding protein H 0.013
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.013
Cbl Casitas B-lineage lymphoma 0.013
Htr5a 5-hydroxytryptamine (serotonin) receptor 5A 0.013
St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.013
Slc22a8 solute carrier family 22 (organic anion transporter), member 8 0.013
P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 0.012
Tinagl1 tubulointerstitial nephritis antigen-like 1 0.012
Acot4 acyl-CoA thioesterase 4 0.012
Oprm1 opioid receptor, mu 1 0.012
Cntn2 contactin 2 0.012
Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 0.012
Il2rb interleukin 2 receptor, beta chain 0.012
Ror1 receptor tyrosine kinase-like orphan receptor 1 0.012
Kif17 kinesin family member 17 0.012
Gnrh1 gonadotropin releasing hormone 1 0.012
Per3 period homolog 3 (Drosophila) 0.012
Gcgr glucagon receptor 0.011
Chrna5 cholinergic receptor, nicotinic, alpha polypeptide 5 0.011
Snn stannin 0.011
Vdr vitamin D receptor 0.011
A4galt alpha 1,4-galactosyltransferase 0.011
Crhr1 corticotropin releasing hormone receptor 1 0.011
Tcta T-cell leukemia translocation altered gene 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
Avpr1b arginine vasopressin receptor 1B 0.805
Krt4 keratin 4 0.326
Th tyrosine hydroxylase 0.270
Chrna1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.250
Ptafr platelet-activating factor receptor 0.204
Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 0.197
Pitx3 paired-like homeodomain 3 0.196
Htr3a 5-hydroxytryptamine (serotonin) receptor 3a 0.195
Strn striatin, calmodulin binding protein 0.170
Adora1 adenosine A1 receptor 0.169
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.167
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.167
Tff1 trefoil factor 1 0.158
St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.151
Espn espin 0.127
Muc3a mucin 3A, cell surface associated 0.120
Olr1361 olfactory receptor 1361 0.118
Uncx UNC homeobox 0.115
Fev FEV (ETS oncogene family) 0.104
Grik1 glutamate receptor, ionotropic, kainate 1 0.102
Itgb7 integrin, beta 7 0.096
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.095
Chrnb1 cholinergic receptor, nicotinic, beta 1 (muscle) 0.094
Prl prolactin 0.090
Myh3 myosin, heavy chain 3, skeletal muscle, embryonic 0.088
Ppp2r2c protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform 0.085
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.080
Padi2 peptidyl arginine deiminase, type II 0.078
Grp gastrin releasing peptide 0.077
Mag myelin-associated glycoprotein 0.077
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.075
Cacng1 calcium channel, voltage-dependent, gamma subunit 1 0.074
Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 0.073
Grid1 glutamate receptor, ionotropic, delta 1 0.073
Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 0.072
Ptprd protein tyrosine phosphatase, receptor type, D 0.070
Kcnn1 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 0.069
Avpr2 arginine vasopressin receptor 2 0.068
Epha3 Eph receptor A3 0.068
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.068
Khk ketohexokinase 0.067
Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.066
Il13 interleukin 13 0.064
Aif1l allograft inflammatory factor 1-like 0.064
Caly calcyon neuron-specific vesicular protein 0.064
Myo16 myosin XVI 0.064
Clstn3 calsyntenin 3 0.063
Calca calcitonin-related polypeptide alpha 0.062
Oprl1 opiate receptor-like 1 0.061
Chrne cholinergic receptor, nicotinic, epsilon 0.059
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.058
Smad3 SMAD family member 3 0.058
Adrbk2 adrenergic, beta, receptor kinase 2 0.056
Pde1b phosphodiesterase 1B, calmodulin-dependent 0.055
LOC100360919 Immunoglobulin lambda-like polypeptide 1-like 0.055
Hrh4 histamine receptor H4 0.054
Gabbr1 gamma-aminobutyric acid (GABA) B receptor 1 0.054
Adcy2 adenylate cyclase 2 (brain) 0.052
Git1 G protein-coupled receptor kinase interacting ArfGAP 1 0.052
Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 0.051
Galr2 galanin receptor 2 0.051
Cntn2 contactin 2 (axonal) 0.050
Aven apoptosis, caspase activation inhibitor 0.049
Cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.049
Slc32a1 solute carrier family 32 (GABA vesicular transporter), member 1 0.049
Rgs9 regulator of G-protein signaling 9 0.048
Gabre gamma-aminobutyric acid (GABA) A receptor, epsilon 0.047
Macf1 microtubule-actin crosslinking factor 1 0.047
Vom2r53 vomeronasal 2 receptor, 53 0.046
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.044
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.044
Drd1a dopamine receptor D1A 0.044
Pla2g2c phospholipase A2, group IIC 0.044
Cel carboxyl ester lipase 0.042
Tbr1 T-box, brain, 1 0.041
Mylk2 myosin light chain kinase 2 0.041
Catsper2 cation channel, sperm associated 2 0.041
Slc7a3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 0.040
Chrnb4 cholinergic receptor, nicotinic, beta 4 0.040
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.039
Chat choline acetyltransferase 0.039
Pou3f4 POU class 3 homeobox 4 0.039
Cacng5 calcium channel, voltage-dependent, gamma subunit 5 0.038
Acr acrosin 0.038
Chrm3 cholinergic receptor, muscarinic 3 0.038
Grm4 glutamate receptor, metabotropic 4 0.038
Oprm1 opioid receptor, mu 1 0.038
Atxn1 ataxin 1 0.038
Opn1mw opsin 1 (cone pigments), medium-wave-sensitive 0.037
Pcsk4 proprotein convertase subtilisin/kexin type 4 0.036
Mpp2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.036
Impg2 interphotoreceptor matrix proteoglycan 2 0.036
Sncb synuclein, beta 0.036
Lim2 lens intrinsic membrane protein 2 0.035
Rin1 Ras and Rab interactor 1 0.035
Slc22a25 solute carrier family 22, member 25 0.034
Mmp7 matrix metallopeptidase 7 0.034
Apba1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.034
Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 0.034
Calcrl calcitonin receptor-like 0.034
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism