The network for 'cyclic nucleotide metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cyclic nucleotide metabolic process

The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.

Homo sapiens
Name Description Probability Func Analog Organism
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.000
IL8 interleukin 8 1.000
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.999
PDZD3 PDZ domain containing 3 0.999
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.998
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.997
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.994
VEGFA vascular endothelial growth factor A 0.994
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.994
GUCY2C guanylate cyclase 2C (heat stable enterotoxin receptor) 0.993
DRD2 dopamine receptor D2 0.993
CXCL2 chemokine (C-X-C motif) ligand 2 0.993
CCR5 chemokine (C-C motif) receptor 5 0.990
ADORA2A adenosine A2a receptor 0.982
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.979
CRHR1 corticotropin releasing hormone receptor 1 0.976
NRP1 neuropilin 1 0.967
CCL5 chemokine (C-C motif) ligand 5 0.965
FHL1 four and a half LIM domains 1 0.964
IL1B interleukin 1, beta 0.954
CXCL3 chemokine (C-X-C motif) ligand 3 0.951
CAV1 caveolin 1, caveolae protein, 22kDa 0.951
KIAA1683 KIAA1683 0.947
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.919
CXCL10 chemokine (C-X-C motif) ligand 10 0.916
DPP4 dipeptidyl-peptidase 4 0.909
CCL20 chemokine (C-C motif) ligand 20 0.908
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.905
IFNG interferon, gamma 0.900
CXCL11 chemokine (C-X-C motif) ligand 11 0.886
IL6 interleukin 6 (interferon, beta 2) 0.883
NOSTRIN nitric oxide synthase trafficker 0.881
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.878
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.876
CXCL5 chemokine (C-X-C motif) ligand 5 0.871
CXCR5 chemokine (C-X-C motif) receptor 5 0.863
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.860
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.858
CALCRL calcitonin receptor-like 0.842
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.833
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.830
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.827
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.819
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.810
HP haptoglobin 0.792
PTEN phosphatase and tensin homolog 0.761
CRH corticotropin releasing hormone 0.753
MT1A metallothionein 1A 0.735
CCL2 chemokine (C-C motif) ligand 2 0.731
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.725
CCL22 chemokine (C-C motif) ligand 22 0.697
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.689
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.668
NAMPT nicotinamide phosphoribosyltransferase 0.667
ARRB1 arrestin, beta 1 0.666
BBS10 Bardet-Biedl syndrome 10 0.661
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.633
MAPT microtubule-associated protein tau 0.613
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.612
PLAUR plasminogen activator, urokinase receptor 0.602
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.578
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.577
MPDZ multiple PDZ domain protein 0.550
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.545
CXCL9 chemokine (C-X-C motif) ligand 9 0.544
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.534
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.527
RGS20 regulator of G-protein signaling 20 0.497
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.496
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.480
CCL7 chemokine (C-C motif) ligand 7 0.453
MEOX2 mesenchyme homeobox 2 0.449
CCL11 chemokine (C-C motif) ligand 11 0.443
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like 0.433
PDGFC platelet derived growth factor C 0.428
CCR4 chemokine (C-C motif) receptor 4 0.414
CBX1 chromobox homolog 1 0.412
FKBP8 FK506 binding protein 8, 38kDa 0.410
EPAS1 endothelial PAS domain protein 1 0.398
SOD2 superoxide dismutase 2, mitochondrial 0.394
GHRHR growth hormone releasing hormone receptor 0.388
CCR2 chemokine (C-C motif) receptor 2 0.387
GPR6 G protein-coupled receptor 6 0.369
CD34 CD34 molecule 0.360
APOC1 apolipoprotein C-I 0.358
CXCL13 chemokine (C-X-C motif) ligand 13 0.356
STC1 stanniocalcin 1 0.353
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.335
IL2RB interleukin 2 receptor, beta 0.335
KCNH1 potassium voltage-gated channel, subfamily H (eag-related), member 1 0.333
CXCR3 chemokine (C-X-C motif) receptor 3 0.328
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.327
FZD1 frizzled homolog 1 (Drosophila) 0.324
CCL4 chemokine (C-C motif) ligand 4 0.315
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.314
IL10 interleukin 10 0.310
CALCA calcitonin-related polypeptide alpha 0.309
CXCL12 chemokine (C-X-C motif) ligand 12 0.303
RALGDS ral guanine nucleotide dissociation stimulator 0.303
MATK megakaryocyte-associated tyrosine kinase 0.303
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
daf-11 Protein DAF-11 0.094
pkg-1 Protein PKG-1 0.085
tax-4 Protein TAX-4 0.071
tax-2 Protein TAX-2 0.070
osm-3 Protein OSM-3 0.041
odr-1 Protein ODR-1 0.036
che-1 Protein CHE-1 0.035
odr-3 Protein ODR-3 0.035
gcy-22 Protein GCY-22 0.034
lite-1 Protein LITE-1 0.031
sol-1 Protein SOL-1 0.028
tax-6 Protein TAX-6 0.028
C25E10.12 Protein C25E10.12 0.028
unc-43 Protein UNC-43 0.026
plc-1 Protein PLC-1 0.025
mig-15 Protein MIG-15 0.024
daf-4 Protein DAF-4 0.024
F28E10.1 Protein F28E10.1 0.023
oig-1 Protein OIG-1 0.023
F46C5.2 Protein F46C5.2 0.023
che-3 Protein CHE-3 0.022
daf-7 Protein DAF-7 0.022
nep-21 Protein NEP-21 0.020
dbl-1 Protein DBL-1 0.020
hot-6 Protein HOT-6 0.018
fln-1 Protein FLN-1 0.018
pry-1 Protein PRY-1 0.018
unc-17 Protein UNC-17 0.018
ist-1 Protein IST-1 0.018
T01G1.2 Protein T01G1.2 0.018
gcy-6 Protein GCY-6 0.018
frm-1 Protein FRM-1 0.017
daf-5 Protein DAF-5 0.017
pde-4 Protein PDE-4 0.017
F32B5.7 Protein F32B5.7 0.017
inx-19 Protein INX-19 0.017
T24B8.4 Protein T24B8.4 0.017
F53F10.2 Protein F53F10.2 0.016
ttr-35 Protein TTR-35 0.016
kvs-2 Protein KVS-2 0.016
gon-2 Protein GON-2 0.016
ida-1 Protein IDA-1 0.016
casy-1 Protein CASY-1 0.016
ncr-1 Protein NCR-1 0.016
H18N23.2 Protein H18N23.2 0.016
C01H6.3 Protein C01H6.3 0.015
CELE_T28B8.3 Protein T28B8.3 0.015
unc-25 Protein UNC-25 0.015
E02A10.3 Protein E02A10.3 0.015
crm-1 Protein CRM-1 0.015
madd-4 Protein MADD-4 0.015
C27B7.7 Protein C27B7.7 0.015
unc-7 Protein UNC-7 0.015
best-18 Protein BEST-18 0.015
F46G11.4 Protein F46G11.4 0.015
F07C3.2 Protein F07C3.2 0.015
F57B7.2 Protein F57B7.2 0.014
che-2 Protein CHE-2 0.014
unc-80 Protein UNC-80 0.014
F16B4.5 Protein F16B4.5 0.014
F32A5.4 Protein F32A5.4 0.014
col-105 Protein COL-105 0.014
cwp-1 Protein CWP-1 0.014
rgef-1 Protein RGEF-1 0.014
T19D2.3 Protein T19D2.3 0.014
sek-1 Protein SEK-1 0.014
sng-1 Protein SNG-1 0.013
cpn-3 Protein CPN-3 0.013
C18A3.4 Protein C18A3.4 0.013
ser-3 Protein SER-3 0.013
M02B1.2 Protein M02B1.2 0.013
R90.1 Protein R90.1 0.013
str-8 Protein STR-8 0.013
CELE_R10E8.1 Protein R10E8.1 0.013
D2092.6 Protein D2092.6 0.013
fkh-6 Protein FKH-6 0.013
cwp-2 Protein CWP-2 0.013
glr-5 Protein GLR-5 0.013
cho-1 Protein CHO-1 0.013
lov-1 Protein LOV-1 0.013
CELE_F43G6.4 Protein F43G6.4 0.013
ser-7 Protein SER-7 0.013
grk-2 Protein GRK-2 0.013
Y71H2AM.13 Protein Y71H2AM.13 0.013
prl-1 Protein PRL-1 0.013
axl-1 Protein AXL-1 0.013
ncx-2 Protein NCX-2 0.013
T20F7.5 Protein T20F7.5 0.013
tag-278 Protein TAG-278 0.013
F13B9.1 Protein F13B9.1 0.012
col-56 Protein COL-56 0.012
F46C5.4 Protein F46C5.4 0.012
rps-6 Protein RPS-6 0.012
nas-11 Protein NAS-11 0.012
F26E4.2 Protein F26E4.2 0.012
nac-3 Protein NAC-3 0.012
pll-1 Protein PLL-1 0.012
sri-11 Protein SRI-11 0.012
F40E10.6 Protein F40E10.6 0.012
W05B5.1 Protein W05B5.1 0.012
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
uts1 urotensin 1 0.977
mc4r melanocortin 4 receptor 0.910
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.665
adra2db adrenergic, alpha-2D-, receptor b 0.624
gucy2f guanylate cyclase 2F, retinal 0.581
nf1a neurofibromin 1a 0.543
adrb2a adrenergic receptor, beta 2a 0.526
vipr2 vasoactive intestinal peptide receptor 2 0.490
cyp11b2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.476
calm1a calmodulin 1a 0.469
mc2r melanocortin 2 receptor 0.400
drd2b dopamine receptor D2b 0.391
wu:fv91b12 wu:fv91b12 0.304
osr1 odd-skipped related 1 (Drosophila) 0.261
atp6v0cb ATPase, H+ transporting, lysosomal, V0 subunit c, b 0.255
adra2c adrenergic, alpha-2C-, receptor 0.248
mchr1a melanin-concentrating hormone receptor 1a 0.247
otpa orthopedia homolog a 0.240
LOC559201 similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3) 0.240
cacnb4a calcium channel, voltage-dependent, beta 4a subunit 0.239
mc1r melanocortin 1 receptor 0.239
avpl arginine vasopressin-like 0.233
crhbp corticotropin releasing hormone binding protein 0.221
dbh dopamine beta hydroxylase 0.220
guca1c guanylate cyclase activator 1C 0.218
hmgb1a high-mobility group box 1a 0.217
rerea arginine-glutamic acid dipeptide (RE) repeats a 0.203
adra2b adrenergic, alpha-2B-, receptor 0.176
inka1a induced in neural crest by AP2, 1a 0.176
alx4a aristaless-like homeobox 4a 0.175
ar androgen receptor 0.159
palm paralemmin 0.151
flj13639 flj13639 0.142
calm2a calmodulin 2a (phosphorylase kinase, delta) 0.139
xpo4 exportin 4 0.139
pak1 p21/Cdc42/Rac1-activated kinase 1 0.137
nf1b neurofibromin 1b 0.134
drd3 dopamine receptor D3 0.131
slc25a3a solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a 0.131
atp1b2a ATPase, Na+/K+ transporting, beta 2a polypeptide 0.128
adra2a adrenergic, alpha-2A-, receptor 0.126
cx27.5 connexin 27.5 0.123
mstnb myostatin b 0.117
gnrh2 gonadotropin-releasing hormone 2 0.113
adcyap1a adenylate cyclase activating polypeptide 1a 0.110
fshr follicle stimulating hormone receptor 0.095
th2 tyrosine hydroxylase 2 0.092
adra2da adrenergic, alpha-2D-, receptor a 0.092
ros1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) 0.092
mc5rb melanocortin 5b receptor 0.091
zgc:110179 zgc:110179 0.091
LOC100332193 growth hormone secretagogue receptor type 1-like 0.088
sox4b SRY-box containing gene 4b 0.085
nrl neural retina leucine zipper 0.082
bsk146 brain specific kinase 146 0.080
igf1 insulin-like growth factor 1 0.076
mchr1b melanin-concentrating hormone receptor 1b 0.074
pp pyrophosphatase (inorganic) 0.074
paqr8 progestin and adipoQ receptor family member VIII 0.071
adora2b adenosine A2b receptor 0.069
sst1.1 somatostatin 1, tandem duplicate 1 0.067
gdnf glial cell derived neurotrophic factor 0.067
opn1lw1 opsin 1 (cone pigments), long-wave-sensitive, 1 0.067
gc2 guanylyl cyclase 2 0.066
fes feline sarcoma oncogene 0.066
rag1 recombination activating gene 1 0.065
calcrla calcitonin receptor-like a 0.064
dharma dharma 0.063
kif5c kinesin family member 5C 0.063
atp2b1a ATPase, Ca++ transporting, plasma membrane 1a 0.062
adcyap1r1a adenylate cyclase activating polypeptide 1 receptor 1a 0.061
gsdf gonadal somatic cell derived factor 0.060
opn4l opsin 4, like 0.055
adipoql adiponectin, C1Q and collagen domain containing, like 0.054
cldn2 claudin 2 0.053
zgc:77123 zgc:77123 0.052
pde6c phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.052
tert telomerase reverse transcriptase 0.051
furinb furin (paired basic amino acid cleaving enzyme) b 0.050
npy8br neuropeptide Y receptor Y8b 0.050
rargb retinoic acid receptor, gamma b 0.049
rtn1a reticulon 1a 0.049
vegfab vascular endothelial growth factor Ab 0.049
si:ch211-209p5.2 si:ch211-209p5.2 0.049
chrm2a cholinergic receptor, muscarinic 2a 0.048
gja3 gap junction protein, alpha 3 0.048
cps1 carbamoyl-phosphate synthase 1, mitochondrial 0.047
crabp1a cellular retinoic acid binding protein 1a 0.046
pcdh17 protocadherin 17 0.046
ptpra protein tyrosine phosphatase, receptor type, A 0.044
mpp5b membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5b) 0.044
oxtl oxytocin-like 0.043
slc8a4b solute carrier family 8 (sodium/calcium exchanger), member 4b 0.042
rs1 retinoschisis (X-linked, juvenile) 1 0.042
clstn1 calsyntenin 1 0.042
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.042
plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 0.042
tspan7b tetraspanin 7b 0.041
flot2a flotillin 2a 0.041
si:dkey-228g21.4 si:dkey-228g21.4 0.040
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
dnc dunce 0.920
Nmdar1 NMDA receptor 1 0.838
Tbh Tyramine beta hydroxylase 0.712
Atf-2 Activating transcription factor-2 0.692
Gyc-89Db Guanylyl cyclase at 89Db 0.641
CG13253 CG13253 gene product from transcript CG13253-RB 0.625
Gyc-89Da Guanylyl cyclase at 89Da 0.624
per period 0.613
CG42629 CG42629 gene product from transcript CG42629-RB 0.566
Octbeta2R CG33976 gene product from transcript CG33976-RA 0.520
5-HT1A Serotonin receptor 1A 0.486
InR Insulin-like receptor 0.442
cry cryptochrome 0.376
Shaw Shaker cognate w 0.363
Mst57Db Male-specific RNA 57Db 0.330
Vmat Vesicular monoamine transporter 0.288
Pde8 Phosphodiesterase 8 0.286
fd85E forkhead domain 85E 0.274
tim timeless 0.265
CG34400 CG34400 gene product from transcript CG34400-RD 0.255
CG14686 CG14686 gene product from transcript CG14686-RA 0.234
mtt mangetout 0.229
Rheb CG1081 gene product from transcript CG1081-RA 0.191
CG32813 CG32813 gene product from transcript CG32813-RE 0.187
Gr64e Gustatory receptor 64e 0.170
tau CG31057 gene product from transcript CG31057-RA 0.159
CaMKII Calcium/calmodulin-dependent protein kinase II 0.157
Ilp3 Insulin-like peptide 3 0.150
CG4239 CG4239 gene product from transcript CG4239-RA 0.149
Cng Cyclic-nucleotide-gated ion channel protein 0.144
wun wunen 0.144
AdoR Adenosine receptor 0.132
jeb jelly belly 0.132
Ilp2 Insulin-like peptide 2 0.119
5-HT1B Serotonin receptor 1B 0.116
king-tubby king tubby 0.112
Ank2 Ankyrin 2 0.108
Dh Diuretic hormone 0.105
wit wishful thinking 0.099
CanA1 Calcineurin A1 0.099
oa2 octopamine receptor 2 0.098
Tre Trehalose-sensitivity 0.098
Actbeta Activin-beta 0.091
Spn31A Serpin 31A 0.089
dnr1 defense repressor 1 0.088
Plc21C Phospholipase C at 21C 0.085
CRMP Collapsin Response Mediator Protein 0.073
Dyb Dystrobrevin-like 0.072
Fad2 CG7923 gene product from transcript CG7923-RA 0.071
Ric Ras which interacts with Calmodulin 0.069
Ih I[[h]] channel 0.067
5-HT7 Serotonin receptor 7 0.060
Gr43a Gustatory receptor 43a 0.059
CG16778 CG16778 gene product from transcript CG16778-RA 0.058
rut rutabaga 0.056
KCNQ KCNQ potassium channel 0.055
pain painless 0.055
dm diminutive 0.054
unc79 CG5237 gene product from transcript CG5237-RB 0.053
CG11317 CG11317 gene product from transcript CG11317-RA 0.052
Rdl Resistant to dieldrin 0.052
Gr32a Gustatory receptor 32a 0.051
Traf-like TNF-receptor-associated factor-like 0.050
uzip unzipped 0.050
htl heartless 0.050
Eaat2 Excitatory amino acid transporter 2 0.049
mAcR-60C muscarinic Acetylcholine Receptor 60C 0.049
nord CG30418 gene product from transcript CG30418-RA 0.048
CG1358 CG1358 gene product from transcript CG1358-RD 0.047
smi35A smell impaired 35A 0.047
p130CAS CG1212 gene product from transcript CG1212-RA 0.047
RanBPM Ran-binding protein M 0.046
G-salpha60A G protein salpha 60A 0.046
Ac3 CG1506 gene product from transcript CG1506-RA 0.046
amon amontillado 0.044
CG8481 CG8481 gene product from transcript CG8481-RB 0.044
Ef1alpha48D Elongation factor 1alpha48D 0.044
tomosyn CG17762 gene product from transcript CG17762-RB 0.044
dpr defective proboscis extension response 0.043
PIP5K59B CG3682 gene product from transcript CG3682-RE 0.042
Pdp1 PAR-domain protein 1 0.041
Gyc88E Guanylyl cyclase at 88E 0.040
Ac76E Adenylyl cyclase 76E 0.040
CG33203 CG33203 gene product from transcript CG33203-RB 0.038
klg klingon 0.038
Nrx-1 Neurexin 1 0.037
slo slowpoke 0.037
DopR Dopamine receptor 0.037
dpr9 CG33485 gene product from transcript CG33485-RA 0.037
beta4GalNAcTA CG8536 gene product from transcript CG8536-RA 0.037
GABA-B-R2 metabotropic GABA-B receptor subtype 2 0.036
Eip63F-1 Ecdysone-induced protein 63F 1 0.036
Frq2 Frequenin 2 0.036
GluRIIB Glutamate receptor IIB 0.036
2mit CG42573 gene product from transcript CG42573-RA 0.035
unc-13 CG2999 gene product from transcript CG2999-RA 0.035
Alk CG8250 gene product from transcript CG8250-RA 0.034
CG17826 CG17826 gene product from transcript CG17826-RA 0.034
moody CG4322 gene product from transcript CG4322-RD 0.034
CG14864 CG14864 gene product from transcript CG14864-RB 0.033
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Esr1 estrogen receptor 1 (alpha) 0.854
Drd2 dopamine receptor D2 0.833
Adrb1 adrenergic receptor, beta 1 0.787
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.766
Kl klotho 0.732
Cckbr cholecystokinin B receptor 0.640
Hif1a hypoxia inducible factor 1, alpha subunit 0.603
Vegfa vascular endothelial growth factor A 0.562
Nos1 nitric oxide synthase 1, neuronal 0.544
Pomc pro-opiomelanocortin-alpha 0.510
Ednra endothelin receptor type A 0.479
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.461
Oprm1 opioid receptor, mu 1 0.434
Ctnnb1 catenin (cadherin associated protein), beta 1 0.410
Thrb thyroid hormone receptor beta 0.410
Pten phosphatase and tensin homolog 0.389
Adra2a adrenergic receptor, alpha 2a 0.373
Foxo3 forkhead box O3 0.352
Kiss1 KiSS-1 metastasis-suppressor 0.351
Nos3 nitric oxide synthase 3, endothelial cell 0.321
Syn2 synapsin II 0.320
Acr acrosin prepropeptide 0.282
Shc3 src homology 2 domain-containing transforming protein C3 0.280
Oprk1 opioid receptor, kappa 1 0.278
Ghr growth hormone receptor 0.272
Pnpla2 patatin-like phospholipase domain containing 2 0.270
Acvr1 activin A receptor, type 1 0.267
Sstr4 somatostatin receptor 4 0.265
Kit kit oncogene 0.263
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.253
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.248
Pdgfb platelet derived growth factor, B polypeptide 0.238
Notch2 Notch gene homolog 2 (Drosophila) 0.230
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.218
Thra thyroid hormone receptor alpha 0.215
Prkar1b protein kinase, cAMP dependent regulatory, type I beta 0.212
Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.212
Ar androgen receptor 0.211
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.211
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.207
Kcnh1 potassium voltage-gated channel, subfamily H (eag-related), member 1 0.206
Slc16a8 solute carrier family 16 (monocarboxylic acid transporters), member 8 0.200
Npc1 Niemann Pick type C1 0.199
Atp4a ATPase, H+/K+ exchanging, gastric, alpha polypeptide 0.193
Tac2 tachykinin 2 0.186
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.186
Plxnd1 plexin D1 0.185
Npy1r neuropeptide Y receptor Y1 0.185
Crhr1 corticotropin releasing hormone receptor 1 0.182
Aatk apoptosis-associated tyrosine kinase 0.177
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.176
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.168
Oxt oxytocin 0.168
Ednrb endothelin receptor type B 0.165
Vip vasoactive intestinal polypeptide 0.163
Gabbr2 gamma-aminobutyric acid (GABA) B receptor, 2 0.160
Grid1 glutamate receptor, ionotropic, delta 1 0.160
Mdm2 transformed mouse 3T3 cell double minute 2 0.158
Rgs9 regulator of G-protein signaling 9 0.157
Pgr progesterone receptor 0.155
Gnrh1 gonadotropin releasing hormone 1 0.153
Nodal nodal 0.149
Pkd1 polycystic kidney disease 1 homolog 0.148
Kcnk4 potassium channel, subfamily K, member 4 0.145
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.145
Cplx1 complexin 1 0.142
Smad2 MAD homolog 2 (Drosophila) 0.141
Sstr1 somatostatin receptor 1 0.140
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.139
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.138
Ppyr1 pancreatic polypeptide receptor 1 0.135
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.135
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D 0.134
Sntb1 syntrophin, basic 1 0.133
Mapk3 mitogen-activated protein kinase 3 0.132
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.130
Ccl8 chemokine (C-C motif) ligand 8 0.130
Grm1 glutamate receptor, metabotropic 1 0.129
Rgr retinal G protein coupled receptor 0.129
Zp1 zona pellucida glycoprotein 1 0.126
Tshr thyroid stimulating hormone receptor 0.125
Gsx1 GS homeobox 1 0.124
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.123
Trpm1 transient receptor potential cation channel, subfamily M, member 1 0.122
Lep leptin 0.122
Prkaca protein kinase, cAMP dependent, catalytic, alpha 0.121
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.118
Prph2 peripherin 2 0.118
Slc12a5 solute carrier family 12, member 5 0.118
Npy2r neuropeptide Y receptor Y2 0.118
Gucy1a3 guanylate cyclase 1, soluble, alpha 3 0.117
Fzd4 frizzled homolog 4 (Drosophila) 0.115
Arhgef25 Rho guanine nucleotide exchange factor (GEF) 25 0.114
BC089491 cDNA sequence BC089491 0.113
Clcnka chloride channel Ka 0.113
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.113
Htr5b 5-hydroxytryptamine (serotonin) receptor 5B 0.112
Nrp1 neuropilin 1 0.111
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.110
Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 0.109
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Rattus norvegicus
Name Description Probability Func Analog Organism
Crhr1 corticotropin releasing hormone receptor 1 0.517
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.409
Olr416 olfactory receptor 416 0.373
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.330
Testin testin gene 0.325
Gucy1a3 guanylate cyclase 1, soluble, alpha 3 0.319
Hrh3 histamine receptor H3 0.306
Gpr6 G protein-coupled receptor 6 0.276
Calcr calcitonin receptor 0.275
Fgf14 fibroblast growth factor 14 0.270
Hpca hippocalcin 0.247
Kcnb2 potassium voltage gated channel, Shab-related subfamily, member 2 0.207
Aqp2 aquaporin 2 (collecting duct) 0.191
Drd2 dopamine receptor D2 0.187
Cxcl10 chemokine (C-X-C motif) ligand 10 0.187
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.185
Uhmk1 U2AF homology motif (UHM) kinase 1 0.183
Crhbp corticotropin releasing hormone binding protein 0.169
Olr1078 olfactory receptor 1078 0.168
Dlg4 discs, large homolog 4 (Drosophila) 0.164
Egr4 early growth response 4 0.163
Shox2 short stature homeobox 2 0.162
Scn10a sodium channel, voltage-gated, type X, alpha subunit 0.160
Opn1mw opsin 1 (cone pigments), medium-wave-sensitive 0.157
Olr1356 olfactory receptor 1356 0.157
Bcan brevican 0.141
Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 0.139
Gpr1 G protein-coupled receptor 1 0.136
Olr1082 olfactory receptor 1082 0.136
Prlhr prolactin releasing hormone receptor 0.135
Fcer2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.134
Slc7a12 solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 0.132
Csf1 colony stimulating factor 1 (macrophage) 0.127
Accn3 amiloride-sensitive cation channel 3 0.127
Cdh22 cadherin 22 0.127
Svs1 seminal vesicle secretory protein 1 0.124
Hpcal4 hippocalcin-like 4 0.123
Olr287 olfactory receptor 287 0.122
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.119
Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) 0.119
Syt7 synaptotagmin VII 0.119
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.118
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.116
Odf4 outer dense fiber of sperm tails 4 0.116
Clstn3 calsyntenin 3 0.115
Pax6 paired box 6 0.114
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.114
Oxtr oxytocin receptor 0.112
Ncan neurocan 0.112
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.111
Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 0.110
Col10a1 collagen, type X, alpha 1 0.108
Acrv1 acrosomal vesicle protein 1 0.107
Hcrt hypocretin 0.105
Mc5r melanocortin 5 receptor 0.105
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.105
Chat choline acetyltransferase 0.104
Cgm4 carcinoembryonic antigen gene family 4 0.104
Notch3 Notch homolog 3 (Drosophila) 0.104
Slc23a2 solute carrier family 23 (nucleobase transporters), member 2 0.104
Rho rhodopsin 0.103
Slco6b1 solute carrier organic anion transporter family, member 6b1 0.101
Foxd3 forkhead box D3 0.101
Glra1 glycine receptor, alpha 1 0.101
Gabbr1 gamma-aminobutyric acid (GABA) B receptor 1 0.099
Calm1 calmodulin 1 0.098
Adora1 adenosine A1 receptor 0.097
Hipk3 homeodomain interacting protein kinase 3 0.095
Ctsj cathepsin J 0.095
Gmeb2 glucocorticoid modulatory element binding protein 2 0.095
Gad1 glutamate decarboxylase 1 0.094
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.094
Kctd13 potassium channel tetramerisation domain containing 13 0.093
Vipr2 vasoactive intestinal peptide receptor 2 0.092
Ptp4a2 protein tyrosine phosphatase 4a2 0.092
Thra thyroid hormone receptor alpha 0.091
Map6 microtubule-associated protein 6 0.091
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.091
Impg2 interphotoreceptor matrix proteoglycan 2 0.091
Foxa3 forkhead box A3 0.090
Adra2c adrenergic, alpha-2C-, receptor 0.089
Olr1500 olfactory receptor 1500 0.088
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.086
Sstr1 somatostatin receptor 1 0.085
Syt6 synaptotagmin VI 0.085
Map3k3 mitogen activated protein kinase kinase kinase 3 0.085
RGD1308165 similar to hypothetical protein MGC17337 0.085
Drd1a dopamine receptor D1A 0.085
Flt1 FMS-related tyrosine kinase 1 0.085
Sgp158 proline-rich glycoprotein (sgp158) 0.084
Grip2 glutamate receptor interacting protein 2 0.084
Ddn dendrin 0.084
Rgs4 regulator of G-protein signaling 4 0.083
Syt8 synaptotagmin VIII 0.083
P2ry1 purinergic receptor P2Y, G-protein coupled, 1 0.083
Trhr thyrotropin releasing hormone receptor 0.082
Gcm1 glial cells missing homolog 1 (Drosophila) 0.081
Epn2 epsin 2 0.081
Gal galanin prepropeptide 0.081
Onecut1 one cut homeobox 1 0.080
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CYR1 Cyr1p 0.030
IRA1 Ira1p 0.015
GPB2 Gpb2p 0.014
MDS3 Mds3p 0.012