IMP
Process View
The network for 'auditory receptor cell fate specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
auditory receptor cell fate specification
The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 1.000 | |
| Msx1 | homeobox, msh-like 1 | 1.000 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 1.000 | |
| Pax6 | paired box gene 6 | 1.000 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.997 | |
| Pax3 | paired box gene 3 | 0.997 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.994 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.994 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.986 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.983 | |
| Fgf8 | fibroblast growth factor 8 | 0.982 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.978 | |
| Foxc2 | forkhead box C2 | 0.976 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.959 | |
| Foxc1 | forkhead box C1 | 0.937 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.915 | |
| Gsc | goosecoid homeobox | 0.914 | |
| Neurod1 | neurogenic differentiation 1 | 0.903 | |
| Lhx3 | LIM homeobox protein 3 | 0.894 | |
| Hoxd13 | homeobox D13 | 0.893 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.892 | |
| Lhx5 | LIM homeobox protein 5 | 0.876 | |
| En1 | engrailed 1 | 0.867 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.851 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.850 | |
| Gpr50 | G-protein-coupled receptor 50 | 0.850 | |
| Sox11 | SRY-box containing gene 11 | 0.844 | |
| Hoxa1 | homeobox A1 | 0.841 | |
| Onecut1 | one cut domain, family member 1 | 0.840 | |
| Gata4 | GATA binding protein 4 | 0.828 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.827 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.798 | |
| Pax2 | paired box gene 2 | 0.792 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.790 | |
| Six3 | sine oculis-related homeobox 3 homolog (Drosophila) | 0.785 | |
| Foxg1 | forkhead box G1 | 0.702 | |
| Neurog3 | neurogenin 3 | 0.691 | |
| Nkx3-2 | NK3 homeobox 2 | 0.682 | |
| Nhlh1 | nescient helix loop helix 1 | 0.677 | |
| Pou4f3 | POU domain, class 4, transcription factor 3 | 0.676 | |
| Sox2 | SRY-box containing gene 2 | 0.672 | |
| Msx2 | homeobox, msh-like 2 | 0.663 | |
| Insm1 | insulinoma-associated 1 | 0.660 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.659 | |
| Tlx3 | T-cell leukemia, homeobox 3 | 0.644 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.640 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.626 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.617 | |
| Hoxd3 | homeobox D3 | 0.606 | |
| Bmp4 | bone morphogenetic protein 4 | 0.599 | |
| Neurog1 | neurogenin 1 | 0.580 | |
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.572 | |
| Lhx9 | LIM homeobox protein 9 | 0.567 | |
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.564 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.558 | |
| Hoxd11 | homeobox D11 | 0.534 | |
| Tbx1 | T-box 1 | 0.532 | |
| T | brachyury | 0.529 | |
| Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.523 | |
| Foxd2 | forkhead box D2 | 0.520 | |
| Myog | myogenin | 0.517 | |
| Efna2 | ephrin A2 | 0.500 | |
| Hmx1 | H6 homeobox 1 | 0.487 | |
| Col22a1 | collagen, type XXII, alpha 1 | 0.485 | |
| Alx3 | aristaless-like homeobox 3 | 0.464 | |
| Gata1 | GATA binding protein 1 | 0.463 | |
| Nog | noggin | 0.462 | |
| Uncx | UNC homeobox | 0.459 | |
| Hoxb1 | homeobox B1 | 0.444 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.443 | |
| Wnt6 | wingless-related MMTV integration site 6 | 0.433 | |
| Dlx5 | distal-less homeobox 5 | 0.411 | |
| Gdf11 | growth differentiation factor 11 | 0.403 | |
| Ntf3 | neurotrophin 3 | 0.376 | |
| Sall3 | sal-like 3 (Drosophila) | 0.376 | |
| Hoxa13 | homeobox A13 | 0.372 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.370 | |
| Pou3f2 | POU domain, class 3, transcription factor 2 | 0.366 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.361 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.360 | |
| Hoxd1 | homeobox D1 | 0.353 | |
| Lhx1 | LIM homeobox protein 1 | 0.342 | |
| Prrx2 | paired related homeobox 2 | 0.336 | |
| Mecom | MDS1 and EVI1 complex locus | 0.335 | |
| Sox9 | SRY-box containing gene 9 | 0.322 | |
| Ebf3 | early B-cell factor 3 | 0.321 | |
| Fgf17 | fibroblast growth factor 17 | 0.320 | |
| Mesp1 | mesoderm posterior 1 | 0.311 | |
| Hmx3 | H6 homeobox 3 | 0.311 | |
| Sim2 | single-minded homolog 2 (Drosophila) | 0.302 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.297 | |
| Col2a1 | collagen, type II, alpha 1 | 0.290 | |
| Fgf15 | fibroblast growth factor 15 | 0.290 | |
| Srrm4 | serine/arginine repetitive matrix 4 | 0.269 | |
| Chrd | chordin | 0.267 | |
| Nkx1-2 | NK1 transcription factor related, locus 2 (Drosophila) | 0.265 | |
| Foxe3 | forkhead box E3 | 0.265 | |
| Zic1 | zinc finger protein of the cerebellum 1 | 0.264 | |
| Foxb1 | forkhead box B1 | 0.260 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.252 |
Loading network...
Danio rerio
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| dlx5a | distal-less homeobox gene 5a | 0.997 | |
| dlx2a | distal-less homeobox gene 2a | 0.975 | |
| dlx6a | distal-less homeobox gene 6a | 0.955 | |
| dlx4a | distal-less homeobox gene 4a | 0.954 | |
| dlx1a | distal-less homeobox gene 1a | 0.930 | |
| dlx4b | distal-less homeobox gene 4b | 0.905 | |
| dlx2b | distal-less homeobox gene 2b | 0.699 | |
| dlx3b | distal-less homeobox gene 3b | 0.460 | |
| nkx3.2 | NK3 homeobox 2 | 0.354 | |
| hoxa3a | homeo box A3a | 0.246 | |
| emx3 | empty spiracles homeobox 3 | 0.215 | |
| fgf10a | fibroblast growth factor 10a | 0.132 | |
| hoxa2b | homeo box A2b | 0.119 | |
| lhx6 | LIM homeobox 6 | 0.089 | |
| nkx2.3 | NK2 transcription factor related 3 | 0.075 | |
| msxd | muscle segment homeobox D | 0.072 | |
| pitx3 | paired-like homeodomain transcription factor 3 | 0.071 | |
| slc17a7 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 | 0.065 | |
| msxc | muscle segment homeobox C | 0.049 | |
| foxp2 | forkhead box P2 | 0.046 | |
| zgc:111821 | zgc:111821 | 0.045 | |
| six4b | sine oculis homeobox homolog 4b | 0.044 | |
| barx1 | BarH-like homeobox 1 | 0.041 | |
| barhl2 | BarH-like 2 | 0.041 | |
| zgc:112355 | zgc:112355 | 0.041 | |
| col14a1 | collagen, type XIV, alpha 1 | 0.038 | |
| olig3 | oligodendrocyte transcription factor 3 | 0.035 | |
| boc | brother of CDO | 0.035 | |
| mgp | matrix Gla protein | 0.032 | |
| msxe | muscle segment homeobox E | 0.029 | |
| ascl1a | achaete-scute complex-like 1a (Drosophila) | 0.027 | |
| tp63 | tumor protein p63 | 0.026 | |
| alpi | alkaline phosphatase, intestinal | 0.024 | |
| hoxb2a | homeo box B2a | 0.023 | |
| elavl3 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 0.022 | |
| fgf20a | fibroblast growth factor 20a | 0.022 | |
| six2a | sine oculis-related homeobox 2a | 0.022 | |
| hoxb3a | homeo box B3a | 0.022 | |
| bmp2a | bone morphogenetic protein 2a | 0.021 | |
| sox9a | SRY-box containing gene 9a | 0.020 | |
| six1b | sine oculis homeobox homolog 1b | 0.019 | |
| LOC100000500 | sclerostin-like | 0.019 | |
| sema3aa | semaphorin 3aa | 0.019 | |
| pax9 | paired box gene 9 | 0.018 | |
| six4a | sine oculis homeobox homolog 4a | 0.018 | |
| dct | dopachrome tautomerase | 0.018 | |
| hoxb4a | homeo box B4a | 0.017 | |
| runx2b | runt-related transcription factor 2b | 0.017 | |
| runx2a | runt-related transcription factor 2a | 0.017 | |
| vasp | vasodilator-stimulated phosphoprotein | 0.017 | |
| mpz | myelin protein zero | 0.016 | |
| fzd10 | frizzled homolog 10 | 0.016 | |
| col10a1 | collagen, type X, alpha 1 | 0.016 | |
| gdnf | glial cell derived neurotrophic factor | 0.015 | |
| grem2 | gremlin 2, cysteine knot superfamily | 0.015 | |
| atoh1a | atonal homolog 1a | 0.015 | |
| dla | deltaA | 0.015 | |
| nr2e1 | nuclear receptor subfamily 2, group E, member 1 | 0.015 | |
| htr1ab | 5-hydroxytryptamine (serotonin) receptor 1A b | 0.014 | |
| evx1 | even-skipped homeobox 1 | 0.014 | |
| fgf3 | fibroblast growth factor 3 | 0.013 | |
| pitx2 | paired-like homeodomain transcription factor 2 | 0.013 | |
| runx3 | runt-related transcription factor 3 | 0.013 | |
| grm1a | glutamate receptor, metabotropic 1a | 0.013 | |
| fgf24 | fibroblast growth factor 24 | 0.013 | |
| foxa1 | forkhead box A1 | 0.013 | |
| isl2a | islet2a | 0.012 | |
| gcm2 | glial cells missing homolog 2 (Drosophila) | 0.012 | |
| hoxc4a | homeo box C4a | 0.012 | |
| cyp26b1 | cytochrome P450, family 26, subfamily b, polypeptide 1 | 0.012 | |
| nadl1.1 | neural adhesion molecule L1.1 | 0.012 | |
| arx | aristaless related homeobox | 0.012 | |
| fgfr3 | fibroblast growth factor receptor 3 | 0.012 | |
| epb4.1l4 | erythrocyte protein band 4.1-like 4 | 0.012 | |
| lhx5 | LIM homeobox 5 | 0.012 | |
| col2a1a | collagen type II, alpha-1a | 0.012 | |
| msxa | muscle segment homeobox A | 0.012 | |
| sp7 | Sp7 transcription factor | 0.012 | |
| fras1 | Fraser syndrome 1 | 0.012 | |
| neurod4 | neurogenic differentiation 4 | 0.011 | |
| grm5a | glutamate receptor, metabotropic 5a | 0.011 | |
| pcp4a | Purkinje cell protein 4a | 0.011 | |
| bmper | BMP binding endothelial regulator | 0.011 | |
| ascl1b | achaete-scute complex-like 1b (Drosophila) | 0.011 | |
| hoxb6a | homeo box B6a | 0.011 | |
| nkx2.1a | NK2 homeobox 1a | 0.010 | |
| hoxd4a | homeo box D4a | 0.010 | |
| crh | corticotropin releasing hormone | 0.010 | |
| tlx2 | T-cell leukemia, homeobox 2 | 0.010 | |
| th | tyrosine hydroxylase | 0.010 | |
| six1a | sine oculis homeobox homolog 1a | 0.010 |