IMP
Process View
The network for 'regulation of endothelial cell migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of endothelial cell migration
Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Efnb2 | ephrin B2 | 0.999 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.997 | |
| Pax2 | paired box gene 2 | 0.973 | |
| Kdr | kinase insert domain protein receptor | 0.933 | |
| Jag1 | jagged 1 | 0.914 | |
| Ephb2 | Eph receptor B2 | 0.878 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.856 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.854 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.844 | |
| Foxa2 | forkhead box A2 | 0.784 | |
| Pax8 | paired box gene 8 | 0.769 | |
| Epha4 | Eph receptor A4 | 0.754 | |
| Pard3 | par-3 (partitioning defective 3) homolog (C. elegans) | 0.754 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.707 | |
| Shh | sonic hedgehog | 0.701 | |
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.596 | |
| Efnb1 | ephrin B1 | 0.574 | |
| Vegfa | vascular endothelial growth factor A | 0.517 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.516 | |
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.507 | |
| Flt4 | FMS-like tyrosine kinase 4 | 0.477 | |
| Cdh5 | cadherin 5 | 0.477 | |
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.465 | |
| Gata4 | GATA binding protein 4 | 0.455 | |
| Dll1 | delta-like 1 (Drosophila) | 0.434 | |
| Lhx1 | LIM homeobox protein 1 | 0.401 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.398 | |
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.393 | |
| Flt1 | FMS-like tyrosine kinase 1 | 0.389 | |
| Mmp15 | matrix metallopeptidase 15 | 0.369 | |
| Zfpm2 | zinc finger protein, multitype 2 | 0.364 | |
| Eng | endoglin | 0.363 | |
| Nkx2-1 | NK2 homeobox 1 | 0.343 | |
| Fgf10 | fibroblast growth factor 10 | 0.334 | |
| Nog | noggin | 0.328 | |
| Sox18 | SRY-box containing gene 18 | 0.301 | |
| Sox7 | SRY-box containing gene 7 | 0.294 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.285 | |
| Rarg | retinoic acid receptor, gamma | 0.284 | |
| Cldn5 | claudin 5 | 0.273 | |
| Wnt7a | wingless-related MMTV integration site 7A | 0.269 | |
| Tbx2 | T-box 2 | 0.260 | |
| Gata6 | GATA binding protein 6 | 0.252 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.251 | |
| She | src homology 2 domain-containing transforming protein E | 0.229 | |
| Fgf8 | fibroblast growth factor 8 | 0.228 | |
| Notch3 | Notch gene homolog 3 (Drosophila) | 0.227 | |
| Lepr | leptin receptor | 0.223 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.219 | |
| Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.218 | |
| Epas1 | endothelial PAS domain protein 1 | 0.210 | |
| Tcf21 | transcription factor 21 | 0.209 | |
| Gab1 | growth factor receptor bound protein 2-associated protein 1 | 0.205 | |
| Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.191 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.190 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.183 | |
| Psen1 | presenilin 1 | 0.182 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.182 | |
| Nr2f1 | nuclear receptor subfamily 2, group F, member 1 | 0.181 | |
| Cyr61 | cysteine rich protein 61 | 0.175 | |
| Jag2 | jagged 2 | 0.175 | |
| Wnt4 | wingless-related MMTV integration site 4 | 0.174 | |
| Sema3f | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.173 | |
| Ret | ret proto-oncogene | 0.173 | |
| Bmp4 | bone morphogenetic protein 4 | 0.173 | |
| Fgf5 | fibroblast growth factor 5 | 0.169 | |
| Col4a2 | collagen, type IV, alpha 2 | 0.166 | |
| Robo1 | roundabout homolog 1 (Drosophila) | 0.165 | |
| Ephb3 | Eph receptor B3 | 0.164 | |
| Vax1 | ventral anterior homeobox containing gene 1 | 0.163 | |
| Hoxa1 | homeobox A1 | 0.162 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.161 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.158 | |
| Hoxd11 | homeobox D11 | 0.157 | |
| Cdc42ep1 | CDC42 effector protein (Rho GTPase binding) 1 | 0.151 | |
| Hmx3 | H6 homeobox 3 | 0.150 | |
| Grb2 | growth factor receptor bound protein 2 | 0.149 | |
| Pten | phosphatase and tensin homolog | 0.148 | |
| Fzd8 | frizzled homolog 8 (Drosophila) | 0.147 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.146 | |
| Tgfb1i1 | transforming growth factor beta 1 induced transcript 1 | 0.142 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.141 | |
| Dll4 | delta-like 4 (Drosophila) | 0.137 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.136 | |
| Col4a1 | collagen, type IV, alpha 1 | 0.136 | |
| Foxf1a | forkhead box F1a | 0.134 | |
| Ptk7 | PTK7 protein tyrosine kinase 7 | 0.132 | |
| Jup | junction plakoglobin | 0.132 | |
| Itga3 | integrin alpha 3 | 0.130 | |
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.128 | |
| Tcte3 | t-complex-associated testis expressed 3 | 0.127 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.126 | |
| Tgfbr3 | transforming growth factor, beta receptor III | 0.126 | |
| Hif3a | hypoxia inducible factor 3, alpha subunit | 0.122 | |
| Cyp26a1 | cytochrome P450, family 26, subfamily a, polypeptide 1 | 0.119 | |
| Pcdh12 | protocadherin 12 | 0.118 | |
| Amh | anti-Mullerian hormone | 0.116 | |
| Acvrl1 | activin A receptor, type II-like 1 | 0.116 | |
| Cdx1 | caudal type homeobox 1 | 0.115 | |
| Col13a1 | collagen, type XIII, alpha 1 | 0.114 |
Loading network...
Danio rerio
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| kdrl | kinase insert domain receptor like | 0.113 | |
| bmp2b | bone morphogenetic protein 2b | 0.047 | |
| ccm2 | cerebral cavernous malformation 2 | 0.032 | |
| plcg1 | phospholipase C, gamma 1 | 0.024 | |
| dld | deltaD | 0.019 | |
| dlb | deltaB | 0.017 | |
| notch3 | notch homolog 3 | 0.016 | |
| dlc | deltaC | 0.016 | |
| vegfc | vascular endothelial growth factor c | 0.015 | |
| tal1 | T-cell acute lymphocytic leukemia 1 | 0.015 | |
| ntrk3b | neurotrophic tyrosine kinase, receptor, type 3b | 0.013 | |
| si:ch211-212m21.5 | si:ch211-212m21.5 | 0.012 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 1.000 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.999 | |
| TEK | TEK tyrosine kinase, endothelial | 0.998 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.997 | |
| EGFR | epidermal growth factor receptor | 0.996 | |
| FGFR2 | fibroblast growth factor receptor 2 | 0.996 | |
| JAG1 | jagged 1 | 0.995 | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.995 | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.990 | |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.990 | |
| RARA | retinoic acid receptor, alpha | 0.989 | |
| FYN | FYN oncogene related to SRC, FGR, YES | 0.988 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.987 | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.986 | |
| LAT | linker for activation of T cells | 0.985 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.982 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.979 | |
| NRP1 | neuropilin 1 | 0.977 | |
| TGFB1 | transforming growth factor, beta 1 | 0.962 | |
| VEGFA | vascular endothelial growth factor A | 0.933 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.932 | |
| RXRA | retinoid X receptor, alpha | 0.931 | |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.914 | |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.863 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.862 | |
| FGFR1 | fibroblast growth factor receptor 1 | 0.855 | |
| NOTCH1 | notch 1 | 0.855 | |
| KLF4 | Kruppel-like factor 4 (gut) | 0.853 | |
| NOTCH3 | notch 3 | 0.836 | |
| PLCG1 | phospholipase C, gamma 1 | 0.835 | |
| YAP1 | Yes-associated protein 1 | 0.833 | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.800 | |
| BCL6 | B-cell CLL/lymphoma 6 | 0.795 | |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.787 | |
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.745 | |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.740 | |
| BMP2 | bone morphogenetic protein 2 | 0.717 | |
| SMAD3 | SMAD family member 3 | 0.715 | |
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.697 | |
| FN1 | fibronectin 1 | 0.694 | |
| GRB2 | growth factor receptor-bound protein 2 | 0.682 | |
| FSTL1 | follistatin-like 1 | 0.652 | |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.648 | |
| THBS1 | thrombospondin 1 | 0.623 | |
| PPL | periplakin | 0.591 | |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.584 | |
| SMAD1 | SMAD family member 1 | 0.578 | |
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.577 | |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.540 | |
| AMOT | angiomotin | 0.538 | |
| PDGFC | platelet derived growth factor C | 0.535 | |
| BAG3 | BCL2-associated athanogene 3 | 0.522 | |
| MEF2C | myocyte enhancer factor 2C | 0.521 | |
| NOXA1 | NADPH oxidase activator 1 | 0.510 | |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.503 | |
| NCF1 | neutrophil cytosolic factor 1 | 0.497 | |
| ENG | endoglin | 0.492 | |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.488 | |
| A2M | alpha-2-macroglobulin | 0.486 | |
| SKIL | SKI-like oncogene | 0.475 | |
| LCK | lymphocyte-specific protein tyrosine kinase | 0.472 | |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.458 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.455 | |
| GDF9 | growth differentiation factor 9 | 0.453 | |
| SFN | stratifin | 0.450 | |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.440 | |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.427 | |
| AMOTL1 | angiomotin like 1 | 0.425 | |
| VEGFC | vascular endothelial growth factor C | 0.398 | |
| EFNA1 | ephrin-A1 | 0.366 | |
| MEF2A | myocyte enhancer factor 2A | 0.366 | |
| ANGPT2 | angiopoietin 2 | 0.358 | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.351 | |
| DUSP1 | dual specificity phosphatase 1 | 0.349 | |
| TGFB3 | transforming growth factor, beta 3 | 0.343 | |
| SMAD7 | SMAD family member 7 | 0.329 | |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | 0.328 | |
| ITGB5 | integrin, beta 5 | 0.328 | |
| FBLN1 | fibulin 1 | 0.325 | |
| GDF5 | growth differentiation factor 5 | 0.321 | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.318 | |
| LZTS2 | leucine zipper, putative tumor suppressor 2 | 0.317 | |
| S100B | S100 calcium binding protein B | 0.313 | |
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.296 | |
| FGF10 | fibroblast growth factor 10 | 0.294 | |
| CAV2 | caveolin 2 | 0.293 | |
| TSC22D1 | TSC22 domain family, member 1 | 0.280 | |
| JUN | jun proto-oncogene | 0.276 | |
| COL5A1 | collagen, type V, alpha 1 | 0.273 | |
| BMP4 | bone morphogenetic protein 4 | 0.266 | |
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.264 | |
| ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.260 | |
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.260 | |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.258 | |
| HP | haptoglobin | 0.245 | |
| SLIT2 | slit homolog 2 (Drosophila) | 0.234 | |
| FGA | fibrinogen alpha chain | 0.227 | |
| GAS6 | growth arrest-specific 6 | 0.225 | |
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.219 | |
| FZD1 | frizzled homolog 1 (Drosophila) | 0.211 |