The network for 'cell fate determination involved in pattern specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell fate determination involved in pattern specification

A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.

Mus musculus
Name Description Probability Func Analog Organism
Psen1 presenilin 1 0.983
Shh sonic hedgehog 0.971
Sox2 SRY-box containing gene 2 0.969
Hes1 hairy and enhancer of split 1 (Drosophila) 0.966
Dll1 delta-like 1 (Drosophila) 0.941
Sall4 sal-like 4 (Drosophila) 0.827
Hand2 heart and neural crest derivatives expressed transcript 2 0.820
Emx1 empty spiracles homolog 1 (Drosophila) 0.814
Dll4 delta-like 4 (Drosophila) 0.735
Foxg1 forkhead box G1 0.717
Fgf8 fibroblast growth factor 8 0.703
Otx2 orthodenticle homolog 2 (Drosophila) 0.643
Jag1 jagged 1 0.591
Notch1 Notch gene homolog 1 (Drosophila) 0.546
Notch2 Notch gene homolog 2 (Drosophila) 0.543
Ptf1a pancreas specific transcription factor, 1a 0.526
Cpeb3 cytoplasmic polyadenylation element binding protein 3 0.507
Chd7 chromodomain helicase DNA binding protein 7 0.473
Pitx2 paired-like homeodomain transcription factor 2 0.464
Gli2 GLI-Kruppel family member GLI2 0.443
Pdx1 pancreatic and duodenal homeobox 1 0.422
Pax6 paired box gene 6 0.412
Hes3 hairy and enhancer of split 3 (Drosophila) 0.397
Nog noggin 0.393
Hand1 heart and neural crest derivatives expressed transcript 1 0.356
Lhx3 LIM homeobox protein 3 0.347
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.342
Pou5f1 POU domain, class 5, transcription factor 1 0.336
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.295
Ctnnb1 catenin (cadherin associated protein), beta 1 0.278
Isl1 ISL1 transcription factor, LIM/homeodomain 0.277
Fgfr1 fibroblast growth factor receptor 1 0.276
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.263
Atoh7 atonal homolog 7 (Drosophila) 0.255
Nkx2-6 NK2 transcription factor related, locus 6 (Drosophila) 0.245
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.242
Nkx6-1 NK6 homeobox 1 0.238
Fgfr2 fibroblast growth factor receptor 2 0.238
Gata6 GATA binding protein 6 0.237
Mesp1 mesoderm posterior 1 0.230
Insm1 insulinoma-associated 1 0.225
Nkx2-9 NK2 transcription factor related, locus 9 (Drosophila) 0.217
Lhx5 LIM homeobox protein 5 0.217
Eya1 eyes absent 1 homolog (Drosophila) 0.213
Fgf15 fibroblast growth factor 15 0.210
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.202
Zfp362 zinc finger protein 362 0.201
Gja5 gap junction protein, alpha 5 0.191
Gsc goosecoid homeobox 0.191
Tlx2 T-cell leukemia, homeobox 2 0.181
Fgf3 fibroblast growth factor 3 0.178
Hmx1 H6 homeobox 1 0.177
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.176
Hoxd3 homeobox D3 0.169
Evx2 even skipped homeotic gene 2 homolog 0.163
Vax1 ventral anterior homeobox containing gene 1 0.160
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.145
Zeb1 zinc finger E-box binding homeobox 1 0.145
Cdx1 caudal type homeobox 1 0.141
Tlx3 T-cell leukemia, homeobox 3 0.138
Rb1 retinoblastoma 1 0.136
Foxa2 forkhead box A2 0.131
Mdfi MyoD family inhibitor 0.128
Sall3 sal-like 3 (Drosophila) 0.127
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.125
Otp orthopedia homolog (Drosophila) 0.117
Egfl7 EGF-like domain 7 0.115
Sox11 SRY-box containing gene 11 0.115
Msx1 homeobox, msh-like 1 0.112
Sox9 SRY-box containing gene 9 0.112
Nkx3-2 NK3 homeobox 2 0.111
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.109
Sycn syncollin 0.108
Lama5 laminin, alpha 5 0.108
Stx12 syntaxin 12 0.105
Rtn4r reticulon 4 receptor 0.104
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.104
Nobox NOBOX oogenesis homeobox 0.103
Arx aristaless related homeobox 0.101
Hoxd13 homeobox D13 0.100
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.100
Spdef SAM pointed domain containing ets transcription factor 0.099
Smo smoothened homolog (Drosophila) 0.098
Sox3 SRY-box containing gene 3 0.097
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.095
Omp olfactory marker protein 0.093
Prph2 peripherin 2 0.093
Foxc1 forkhead box C1 0.091
Sox1 SRY-box containing gene 1 0.090
Tcfap2a transcription factor AP-2, alpha 0.089
Tcf15 transcription factor 15 0.089
Socs1 suppressor of cytokine signaling 1 0.086
Neurog3 neurogenin 3 0.086
Fgf17 fibroblast growth factor 17 0.084
Tbx5 T-box 5 0.083
Foxc2 forkhead box C2 0.083
Prr15 proline rich 15 0.083
Vegfa vascular endothelial growth factor A 0.082
Pitx3 paired-like homeodomain transcription factor 3 0.081
Tgfb2 transforming growth factor, beta 2 0.080
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
lag-2 Protein LAG-2 0.017
elt-6 Protein ELT-6 0.013
sel-8 Protein SEL-8 0.012
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
E(spl) Enhancer of split 1.000
HLHmdelta E(spl) region transcript mdelta 1.000
HLHmgamma E(spl) region transcript mgamma 1.000
HLHm7 E(spl) region transcript m7 0.999
HLHm5 E(spl) region transcript m5 0.999
malpha E(spl) region transcript malpha 0.999
Tom Twin of m4 0.999
m4 E(spl) region transcript m4 0.991
ato atonal 0.987
Su(H) Suppressor of Hairless 0.926
ac achaete 0.871
HLHmbeta E(spl) region transcript mbeta 0.834
amos absent MD neurons and olfactory sensilla 0.680
tin tinman 0.561
m2 E(spl) region transcript m2 0.548
HLHm3 E(spl) region transcript m3 0.436
sens senseless 0.400
sca scabrous 0.399
ase asense 0.338
sc scute 0.272
ed echinoid 0.263
BobA Brother of Bearded A 0.237
dsh dishevelled 0.162
fz frizzled 0.126
sna snail 0.125
ham hamlet 0.117
neur neuralized 0.105
m6 E(spl) region transcript m6 0.103
spdo sanpodo 0.095
bin biniou 0.089
stg string 0.088
eg eagle 0.086
Notum CG13076 gene product from transcript CG13076-RB 0.085
N Notch 0.085
sv shaven 0.082
ro rough 0.076
stan starry night 0.070
Dl Delta 0.041
Ser Serrate 0.037
nau nautilus 0.037
gcm glial cells missing 0.036
H Hairless 0.034
dpn deadpan 0.031
dx deltex 0.031
eyg eyegone 0.030
Tollo CG6890 gene product from transcript CG6890-RA 0.026
CG1104 CG1104 gene product from transcript CG1104-RB 0.024
CG32702 CG32702 gene product from transcript CG32702-RB 0.023
Gef26 CG9491 gene product from transcript CG9491-RB 0.023
klu klumpfuss 0.021
pnr pannier 0.020
CG3227 CG3227 gene product from transcript CG3227-RA 0.020
prc pericardin 0.020
Eps-15 Epidermal growth factor receptor pathway substrate clone 15 0.019
Cpr97Eb Cuticular protein 97Eb 0.018
not non-stop 0.018
bap bagpipe 0.018
FBX011 FBX011 ortholog 0.017
calypso CG8445 gene product from transcript CG8445-RB 0.017
wdb widerborst 0.017
Proct Proctolin 0.016
CG42709 CG42709 gene product from transcript CG42709-RC 0.016
B-H2 BarH2 0.016
Gsc Goosecoid 0.015
dy dusky 0.015
CG31961 CG31961 gene product from transcript CG31961-RA 0.015
CG4699 CG4699 gene product from transcript CG4699-RJ 0.014
tap target of Poxn 0.014
lmd lame duck 0.014
Sp1 CG1343 gene product from transcript CG1343-RB 0.013
CG15365 CG15365 gene product from transcript CG15365-RA 0.013
Poxn Pox neuro 0.012
CG3081 CG3081 gene product from transcript CG3081-RA 0.012
CG6520 CG6520 gene product from transcript CG6520-RA 0.012
CG11592 CG11592 gene product from transcript CG11592-RA 0.012
ari-1 ariadne 0.012
DopR Dopamine receptor 0.011
tll tailless 0.011
Msi Male-specific insect derived growth factor 0.011
l(1)G0289 lethal (1) G0289 0.011
nub nubbin 0.011
Tis11 Tis11 homolog 0.010
esg escargot 0.010
Mec2 CG7635 gene product from transcript CG7635-RA 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism