IMP
Process View
The network for 'positive regulation of synaptic plasticity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of synaptic plasticity
A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Neurod1 | neurogenic differentiation 1 | 0.998 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.994 | |
| Neurod4 | neurogenic differentiation 4 | 0.982 | |
| Pax6 | paired box gene 6 | 0.935 | |
| Neurog2 | neurogenin 2 | 0.933 | |
| Neurog3 | neurogenin 3 | 0.874 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.868 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.867 | |
| Shh | sonic hedgehog | 0.757 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.674 | |
| Onecut1 | one cut domain, family member 1 | 0.606 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.604 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.587 | |
| Gata1 | GATA binding protein 1 | 0.579 | |
| Mecom | MDS1 and EVI1 complex locus | 0.549 | |
| Nhlh1 | nescient helix loop helix 1 | 0.547 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.449 | |
| Msx1 | homeobox, msh-like 1 | 0.427 | |
| Insm1 | insulinoma-associated 1 | 0.422 | |
| Lhx3 | LIM homeobox protein 3 | 0.372 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.370 | |
| Mab21l2 | mab-21-like 2 (C. elegans) | 0.364 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.342 | |
| Ilk | integrin linked kinase | 0.340 | |
| Foxd4 | forkhead box D4 | 0.334 | |
| Gpr50 | G-protein-coupled receptor 50 | 0.333 | |
| Lhx5 | LIM homeobox protein 5 | 0.332 | |
| Efna2 | ephrin A2 | 0.307 | |
| Gdf11 | growth differentiation factor 11 | 0.306 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.292 | |
| Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.274 | |
| Kcnq2 | potassium voltage-gated channel, subfamily Q, member 2 | 0.258 | |
| Prph2 | peripherin 2 | 0.243 | |
| Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) | 0.242 | |
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.236 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.235 | |
| Tlx3 | T-cell leukemia, homeobox 3 | 0.234 | |
| Alx3 | aristaless-like homeobox 3 | 0.228 | |
| Hoxb1 | homeobox B1 | 0.227 | |
| Hoxd13 | homeobox D13 | 0.216 | |
| Nkx3-2 | NK3 homeobox 2 | 0.214 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.211 | |
| Mmp24 | matrix metallopeptidase 24 | 0.210 | |
| Mmp9 | matrix metallopeptidase 9 | 0.210 | |
| Hba-x | hemoglobin X, alpha-like embryonic chain in Hba complex | 0.207 | |
| Neurod2 | neurogenic differentiation 2 | 0.206 | |
| Il6 | interleukin 6 | 0.203 | |
| Trim10 | tripartite motif-containing 10 | 0.203 | |
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.202 | |
| Il10 | interleukin 10 | 0.190 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.181 | |
| Elavl4 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) | 0.179 | |
| Mxd3 | Max dimerization protein 3 | 0.179 | |
| T | brachyury | 0.179 | |
| Cdk5r1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.176 | |
| Col9a1 | collagen, type IX, alpha 1 | 0.175 | |
| Tlr4 | toll-like receptor 4 | 0.168 | |
| Chrna3 | cholinergic receptor, nicotinic, alpha polypeptide 3 | 0.163 | |
| Tcf15 | transcription factor 15 | 0.162 | |
| Dlx2 | distal-less homeobox 2 | 0.162 | |
| Slc4a1 | solute carrier family 4 (anion exchanger), member 1 | 0.161 | |
| Sox11 | SRY-box containing gene 11 | 0.161 | |
| Prrx2 | paired related homeobox 2 | 0.157 | |
| Fgf15 | fibroblast growth factor 15 | 0.154 | |
| Ncan | neurocan | 0.153 | |
| Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.152 | |
| Snai1 | snail homolog 1 (Drosophila) | 0.148 | |
| Gata4 | GATA binding protein 4 | 0.145 | |
| Dcc | deleted in colorectal carcinoma | 0.145 | |
| Prph | peripherin | 0.145 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.140 | |
| Hbb-bh1 | hemoglobin Z, beta-like embryonic chain | 0.134 | |
| Dab1 | disabled homolog 1 (Drosophila) | 0.132 | |
| Pou3f2 | POU domain, class 3, transcription factor 2 | 0.132 | |
| Six3 | sine oculis-related homeobox 3 homolog (Drosophila) | 0.132 | |
| Pax3 | paired box gene 3 | 0.131 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.131 | |
| Gypa | glycophorin A | 0.127 | |
| Rhag | Rhesus blood group-associated A glycoprotein | 0.126 | |
| Nkx1-2 | NK1 transcription factor related, locus 2 (Drosophila) | 0.126 | |
| Hbb-y | hemoglobin Y, beta-like embryonic chain | 0.125 | |
| Ebf2 | early B-cell factor 2 | 0.122 | |
| Glra1 | glycine receptor, alpha 1 subunit | 0.122 | |
| Ebf3 | early B-cell factor 3 | 0.121 | |
| Vsx2 | visual system homeobox 2 | 0.121 | |
| Gfra3 | glial cell line derived neurotrophic factor family receptor alpha 3 | 0.120 | |
| Gsc | goosecoid homeobox | 0.119 | |
| Hoxd3 | homeobox D3 | 0.117 | |
| Hoxa10 | homeobox A10 | 0.117 | |
| Foxd2 | forkhead box D2 | 0.113 | |
| Epx | eosinophil peroxidase | 0.109 | |
| Ank1 | ankyrin 1, erythroid | 0.109 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.109 | |
| En1 | engrailed 1 | 0.108 | |
| Plat | plasminogen activator, tissue | 0.106 | |
| Plau | plasminogen activator, urokinase | 0.104 | |
| Col22a1 | collagen, type XXII, alpha 1 | 0.104 | |
| Sim2 | single-minded homolog 2 (Drosophila) | 0.103 | |
| Stmn4 | stathmin-like 4 | 0.103 | |
| Hoxb7 | homeobox B7 | 0.100 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Serpine1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.222 | |
| Mmp3 | matrix metallopeptidase 3 | 0.204 | |
| Calcb | calcitonin-related polypeptide, beta | 0.183 | |
| Racgap1 | Rac GTPase-activating protein 1 | 0.160 | |
| Mmp12 | matrix metallopeptidase 12 | 0.131 | |
| Asf1b | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.124 | |
| Ccnb1 | cyclin B1 | 0.118 | |
| Mmp13 | matrix metallopeptidase 13 | 0.099 | |
| Hrasls5 | HRAS-like suppressor family, member 5 | 0.091 | |
| Ankrd1 | ankyrin repeat domain 1 (cardiac muscle) | 0.076 | |
| Il6 | interleukin 6 | 0.070 | |
| Pip | prolactin induced protein | 0.065 | |
| Olr1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.059 | |
| Top2a | topoisomerase (DNA) II alpha | 0.058 | |
| C1qtnf5 | C1q and tumor necrosis factor related protein 5 | 0.054 | |
| Mmp9 | matrix metallopeptidase 9 | 0.052 | |
| Plk1 | polo-like kinase 1 (Drosophila) | 0.049 | |
| Arhgap10 | Rho GTPase activating protein 10 | 0.048 | |
| Ibsp | integrin-binding sialoprotein | 0.047 | |
| Cd80 | Cd80 molecule | 0.047 | |
| Pttg1 | pituitary tumor-transforming 1 | 0.046 | |
| LOC689399 | hypothetical protein LOC689399 | 0.044 | |
| Mrgprf | MAS-related GPR, member F | 0.043 | |
| Cacnb3 | calcium channel, voltage-dependent, beta 3 subunit | 0.041 | |
| Ltbp3 | latent transforming growth factor beta binding protein 3 | 0.040 | |
| Cdca3 | cell division cycle associated 3 | 0.040 | |
| Vip | vasoactive intestinal peptide | 0.038 | |
| Htr2b | 5-hydroxytryptamine (serotonin) receptor 2B | 0.038 | |
| Cdk1 | cyclin-dependent kinase 1 | 0.037 | |
| Ugt1a7c | UDP glucuronosyltransferase 1 family, polypeptide A7C | 0.035 | |
| Slc6a5 | solute carrier family 6 (neurotransmitter transporter, glycine), member 5 | 0.034 | |
| Csf3 | colony stimulating factor 3 (granulocyte) | 0.033 | |
| Col12a1 | collagen, type XII, alpha 1 | 0.031 | |
| Accn3 | amiloride-sensitive cation channel 3 | 0.030 | |
| Nr4a3 | nuclear receptor subfamily 4, group A, member 3 | 0.029 | |
| Fbln5 | fibulin 5 | 0.029 | |
| Tfec | transcription factor EC | 0.029 | |
| Plau | plasminogen activator, urokinase | 0.028 | |
| Tacr1 | tachykinin receptor 1 | 0.028 | |
| Fam38b | family with sequence similarity 38, member B | 0.028 | |
| Ube2c | ubiquitin-conjugating enzyme E2C | 0.028 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.027 | |
| Olfml2b | olfactomedin-like 2B | 0.026 | |
| Cxcl6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.025 | |
| Ccl11 | chemokine (C-C motif) ligand 11 | 0.025 | |
| Egr2 | early growth response 2 | 0.024 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.024 | |
| Slc2a3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.023 | |
| Foxe3 | forkhead box E3 | 0.023 | |
| Gabrg3 | gamma-aminobutyric acid (GABA) A receptor, gamma 3 | 0.022 | |
| Fmod | fibromodulin | 0.022 | |
| Selp | selectin P | 0.022 | |
| Kifc1 | kinesin family member C1 | 0.022 | |
| Bst1 | bone marrow stromal cell antigen 1 | 0.022 | |
| Cercam | cerebral endothelial cell adhesion molecule | 0.021 | |
| Figf | c-fos induced growth factor | 0.021 | |
| Cenpt | centromere protein T | 0.021 | |
| Glycam1 | glycosylation dependent cell adhesion molecule 1 | 0.020 | |
| Eln | elastin | 0.020 | |
| Gng8 | guanine nucleotide binding protein (G protein), gamma 8 | 0.020 | |
| Klrc1 | killer cell lectin-like receptor subfamily C, member 1 | 0.020 | |
| Cspg4 | chondroitin sulfate proteoglycan 4 | 0.020 | |
| Mmp7 | matrix metallopeptidase 7 | 0.020 | |
| Sfrp4 | secreted frizzled-related protein 4 | 0.019 | |
| Esr2 | estrogen receptor 2 (ER beta) | 0.019 | |
| Kif18b | kinesin family member 18B | 0.018 | |
| Crisp1 | cysteine-rich secretory protein 1 | 0.018 | |
| Mybph | myosin binding protein H | 0.018 | |
| Sele | selectin E | 0.018 | |
| RGD1561143 | similar to cell surface receptor FDFACT | 0.018 | |
| Sprr3 | small proline-rich protein 3 | 0.018 | |
| Nox1 | NADPH oxidase 1 | 0.018 | |
| Pgf | placental growth factor | 0.018 | |
| Ptpn7 | protein tyrosine phosphatase, non-receptor type 7 | 0.018 | |
| Reg3g | regenerating islet-derived 3 gamma | 0.018 | |
| Ereg | epiregulin | 0.017 | |
| Bfsp1 | beaded filament structural protein 1 | 0.017 | |
| Sval1 | seminal vesicle antigen-like 1 | 0.017 | |
| LOC686539 | similar to immunoglobulin superfamily containing leucine-rich repeat | 0.017 | |
| Traf4af1 | TRAF4 associated factor 1 | 0.017 | |
| Slc24a6 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 | 0.017 | |
| Col5a1 | collagen, type V, alpha 1 | 0.017 | |
| Fosl1 | fos-like antigen 1 | 0.016 | |
| Kcnj8 | potassium inwardly-rectifying channel, subfamily J, member 8 | 0.016 | |
| Col1a1 | collagen, type I, alpha 1 | 0.016 | |
| Stxbp2 | syntaxin binding protein 2 | 0.016 | |
| Cpa3 | carboxypeptidase A3, mast cell | 0.016 | |
| Dock8 | dedicator of cytokinesis 8 | 0.016 | |
| Entpd1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.016 | |
| Mcm5 | minichromosome maintenance complex component 5 | 0.016 | |
| Ascl2 | achaete-scute complex homolog 2 (Drosophila) | 0.015 | |
| Tgfb1i1 | transforming growth factor beta 1 induced transcript 1 | 0.015 | |
| Vom1r101 | vomeronasal 1 receptor 101 | 0.015 | |
| Espl1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.015 | |
| Vgf | VGF nerve growth factor inducible | 0.014 | |
| Bcat1 | branched chain aminotransferase 1, cytosolic | 0.014 | |
| Neurl3 | neuralized homolog 3 (Drosophila) | 0.014 | |
| Dlgap5 | discs, large (Drosophila) homolog-associated protein 5 | 0.014 | |
| Chia | chitinase, acidic | 0.014 | |
| Gabrr1 | gamma-aminobutyric acid (GABA) receptor, rho 1 | 0.014 |