The network for 'astrocyte fate commitment' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

astrocyte fate commitment

The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte.

Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Hand1 heart and neural crest derivatives expressed transcript 1 1.000
Pax3 paired box gene 3 1.000
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Fgf8 fibroblast growth factor 8 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Tcfap2a transcription factor AP-2, alpha 0.999
Foxc2 forkhead box C2 0.999
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.999
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.999
Hand2 heart and neural crest derivatives expressed transcript 2 0.999
Isl1 ISL1 transcription factor, LIM/homeodomain 0.999
Msx1 homeobox, msh-like 1 0.998
Pax6 paired box gene 6 0.998
Bmp4 bone morphogenetic protein 4 0.997
Prrx1 paired related homeobox 1 0.997
Eya1 eyes absent 1 homolog (Drosophila) 0.995
Sox11 SRY-box containing gene 11 0.991
Hoxa1 homeobox A1 0.989
Neurod1 neurogenic differentiation 1 0.983
Gli2 GLI-Kruppel family member GLI2 0.976
Pitx2 paired-like homeodomain transcription factor 2 0.976
Prrx2 paired related homeobox 2 0.973
Alx3 aristaless-like homeobox 3 0.971
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.969
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.968
Pax2 paired box gene 2 0.968
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.960
Gbx2 gastrulation brain homeobox 2 0.960
Alx4 aristaless-like homeobox 4 0.957
Tgfb2 transforming growth factor, beta 2 0.951
Onecut1 one cut domain, family member 1 0.951
Foxc1 forkhead box C1 0.950
Sox9 SRY-box containing gene 9 0.943
Dlx5 distal-less homeobox 5 0.940
Meox2 mesenchyme homeobox 2 0.933
Gata4 GATA binding protein 4 0.923
Fgfr2 fibroblast growth factor receptor 2 0.921
Foxd2 forkhead box D2 0.920
Ednra endothelin receptor type A 0.916
Foxg1 forkhead box G1 0.904
Ntf3 neurotrophin 3 0.903
Tbx1 T-box 1 0.893
Hoxd13 homeobox D13 0.888
Hoxd3 homeobox D3 0.887
Smo smoothened homolog (Drosophila) 0.876
Lhx5 LIM homeobox protein 5 0.869
Sall3 sal-like 3 (Drosophila) 0.866
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.862
Gpr50 G-protein-coupled receptor 50 0.861
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.860
Nhlh1 nescient helix loop helix 1 0.855
Col2a1 collagen, type II, alpha 1 0.854
Ptf1a pancreas specific transcription factor, 1a 0.839
Gdnf glial cell line derived neurotrophic factor 0.836
Nkx3-2 NK3 homeobox 2 0.835
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.825
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.821
Emx1 empty spiracles homolog 1 (Drosophila) 0.820
Lhx3 LIM homeobox protein 3 0.816
Nog noggin 0.801
Sox2 SRY-box containing gene 2 0.797
Col22a1 collagen, type XXII, alpha 1 0.793
Neurog1 neurogenin 1 0.780
Gsc goosecoid homeobox 0.774
Efna2 ephrin A2 0.769
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.765
Snai1 snail homolog 1 (Drosophila) 0.757
Hoxb1 homeobox B1 0.746
Rarg retinoic acid receptor, gamma 0.741
Neurog2 neurogenin 2 0.740
Fgf3 fibroblast growth factor 3 0.738
Phox2b paired-like homeobox 2b 0.737
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.732
She src homology 2 domain-containing transforming protein E 0.732
Lmx1a LIM homeobox transcription factor 1 alpha 0.730
Hoxa3 homeobox A3 0.730
Meox1 mesenchyme homeobox 1 0.728
Hoxc5 homeobox C5 0.721
Ebf3 early B-cell factor 3 0.717
Aplnr apelin receptor 0.709
Zeb1 zinc finger E-box binding homeobox 1 0.709
Pdx1 pancreatic and duodenal homeobox 1 0.694
T brachyury 0.691
Fgfr1 fibroblast growth factor receptor 1 0.690
Hoxd11 homeobox D11 0.684
Gata1 GATA binding protein 1 0.682
Bmp7 bone morphogenetic protein 7 0.682
Pax9 paired box gene 9 0.668
Wnt6 wingless-related MMTV integration site 6 0.660
Mecom MDS1 and EVI1 complex locus 0.642
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.641
Uncx UNC homeobox 0.628
Neurog3 neurogenin 3 0.621
Atoh7 atonal homolog 7 (Drosophila) 0.618
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.617
Fgf4 fibroblast growth factor 4 0.610
Pax1 paired box gene 1 0.605
Chrd chordin 0.604
Tcf15 transcription factor 15 0.602
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism