The network for 'mechanoreceptor differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mechanoreceptor differentiation

The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.

Mus musculus
Name Description Probability Func Analog Organism
Ush1g Usher syndrome 1G homolog (human) 1.000
Shh sonic hedgehog 1.000
Cdh23 cadherin 23 (otocadherin) 0.999
Sox2 SRY-box containing gene 2 0.999
Gli3 GLI-Kruppel family member GLI3 0.999
Pten phosphatase and tensin homolog 0.998
Neurod1 neurogenic differentiation 1 0.998
Otx2 orthodenticle homolog 2 (Drosophila) 0.997
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.995
Foxc1 forkhead box C1 0.995
Notch1 Notch gene homolog 1 (Drosophila) 0.995
Chd7 chromodomain helicase DNA binding protein 7 0.995
Ctnnb1 catenin (cadherin associated protein), beta 1 0.995
Pax2 paired box gene 2 0.992
Pou4f3 POU domain, class 4, transcription factor 3 0.990
Pax3 paired box gene 3 0.988
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.988
Kif3a kinesin family member 3A 0.988
Myo6 myosin VI 0.986
Pax6 paired box gene 6 0.979
Hand2 heart and neural crest derivatives expressed transcript 2 0.979
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.976
Foxg1 forkhead box G1 0.970
Ush1c Usher syndrome 1C homolog (human) 0.965
Pcdh15 protocadherin 15 0.960
Ntf3 neurotrophin 3 0.959
Fgfr2 fibroblast growth factor receptor 2 0.952
Myo15 myosin XV 0.949
Thrb thyroid hormone receptor beta 0.946
Eya1 eyes absent 1 homolog (Drosophila) 0.925
Grxcr1 glutaredoxin, cysteine rich 1 0.921
Emx1 empty spiracles homolog 1 (Drosophila) 0.918
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.913
Foxc2 forkhead box C2 0.905
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.902
Whrn whirlin 0.888
Bdnf brain derived neurotrophic factor 0.881
Gpr98 G protein-coupled receptor 98 0.860
Pitx2 paired-like homeodomain transcription factor 2 0.847
Onecut1 one cut domain, family member 1 0.836
Psen1 presenilin 1 0.834
Jag1 jagged 1 0.827
Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 0.826
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.825
Smad4 MAD homolog 4 (Drosophila) 0.815
Msx1 homeobox, msh-like 1 0.811
Grid1 glutamate receptor, ionotropic, delta 1 0.805
Tgfb2 transforming growth factor, beta 2 0.805
Fgfr1 fibroblast growth factor receptor 1 0.804
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.793
Atoh1 atonal homolog 1 (Drosophila) 0.786
Vangl2 vang-like 2 (van gogh, Drosophila) 0.778
Tecta tectorin alpha 0.777
Efnb2 ephrin B2 0.759
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.750
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.749
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.746
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.736
Sox9 SRY-box containing gene 9 0.713
Neurog2 neurogenin 2 0.692
LOC100503041 PDZ domain-containing protein 7-like 0.691
Gopc golgi associated PDZ and coiled-coil motif containing 0.681
Isl1 ISL1 transcription factor, LIM/homeodomain 0.680
Zic3 zinc finger protein of the cerebellum 3 0.676
Fgf8 fibroblast growth factor 8 0.669
Ptk7 PTK7 protein tyrosine kinase 7 0.649
Hes1 hairy and enhancer of split 1 (Drosophila) 0.643
Bmp4 bone morphogenetic protein 4 0.633
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.631
Gabra2 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 0.604
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.603
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.599
Gata4 GATA binding protein 4 0.593
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.589
Ret ret proto-oncogene 0.587
Ptf1a pancreas specific transcription factor, 1a 0.582
Kiss1 KiSS-1 metastasis-suppressor 0.581
Cftr cystic fibrosis transmembrane conductance regulator homolog 0.548
Lhx3 LIM homeobox protein 3 0.547
Srrm4 serine/arginine repetitive matrix 4 0.545
En1 engrailed 1 0.542
Insm1 insulinoma-associated 1 0.542
Dll1 delta-like 1 (Drosophila) 0.539
Adam17 a disintegrin and metallopeptidase domain 17 0.535
Gdf3 growth differentiation factor 3 0.533
Gsc goosecoid homeobox 0.511
Meox2 mesenchyme homeobox 2 0.507
Uncx UNC homeobox 0.500
Efna2 ephrin A2 0.499
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.498
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.487
Sox11 SRY-box containing gene 11 0.485
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.484
Hoxa11 homeobox A11 0.481
Msx2 homeobox, msh-like 2 0.480
Espn espin 0.479
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.479
Wnt3a wingless-related MMTV integration site 3A 0.475
Lhx1 LIM homeobox protein 1 0.472
Prox1 prospero-related homeobox 1 0.463
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
vab-3 Protein VAB-3 0.034
egl-18 Protein EGL-18 0.032
unc-73 Protein UNC-73 0.026
egl-46 Protein EGL-46 0.024
egl-5 Protein EGL-5 0.024
lin-56 Protein LIN-56 0.023
pha-4 Protein PHA-4 0.022
inx-3 Protein INX-3 0.019
mls-2 Protein MLS-2 0.019
elt-6 Protein ELT-6 0.019
che-13 Protein CHE-13 0.019
T09B4.5 Protein T09B4.5 0.018
dys-1 Protein DYS-1 0.017
goa-1 Protein GOA-1 0.017
rpc-1 Protein RPC-1 0.015
ten-1 Protein TEN-1 0.015
dyc-1 Protein DYC-1 0.015
let-60 Protein LET-60 0.015
flt-1 Protein FLT-1 0.014
lin-7 Protein LIN-7 0.014
lin-12 Protein LIN-12 0.013
frm-1 Protein FRM-1 0.013
dyb-1 Protein DYB-1 0.013
ahr-1 Protein AHR-1 0.013
npp-6 Protein NPP-6 0.013
bar-1 Protein BAR-1 0.013
vha-15 Protein VHA-15 0.013
egl-30 Protein EGL-30 0.013
ceh-32 Protein CEH-32 0.013
lin-33 Protein LIN-33 0.012
pept-3 Protein PEPT-3 0.012
pal-1 Protein PAL-1 0.012
F53B3.5 Protein F53B3.5 0.012
CELE_C46C2.2 Protein C46C2.2 0.012
mes-3 Protein MES-3 0.012
mig-38 Protein MIG-38 0.012
tbb-4 Protein TBB-4 0.011
pry-1 Protein PRY-1 0.011
sulp-2 Protein SULP-2 0.011
sel-7 Protein SEL-7 0.011
nhr-31 Protein NHR-31 0.011
cdc-48.3 Protein CDC-48.3 0.011
kcc-1 Protein KCC-1 0.011
nhr-34 Protein NHR-34 0.010
lst-2 Protein LST-2 0.010
sem-5 Protein SEM-5 0.010
ncr-1 Protein NCR-1 0.010
daf-3 Protein DAF-3 0.010
F28B3.1 Protein F28B3.1 0.010
daf-19 Protein DAF-19 0.010
tps-2 Protein TPS-2 0.010
atg-2 Protein ATG-2 0.010
srw-67 Protein SRW-67 0.010
sdz-38 Protein SDZ-38 0.010
CELE_Y64G10A.7 Protein Y64G10A.7 0.010
tag-256 Protein TAG-256 0.010
CELE_F56D5.6 Protein F56D5.6 0.010
gei-8 Protein GEI-8 0.010
daf-5 Protein DAF-5 0.010
egl-36 Protein EGL-36 0.010
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Danio rerio
Name Description Probability Func Analog Organism
dla deltaA 1.000
neurog1 neurogenin 1 0.995
eya1 eyes absent homolog 1 0.981
tbx1 T-box 1 0.978
dlb deltaB 0.976
pax2a paired box gene 2a 0.965
dlc deltaC 0.964
otpb orthopedia homolog b 0.959
atoh1a atonal homolog 1a 0.945
dlx3b distal-less homeobox gene 3b 0.921
isl1 islet1 0.906
dlx5a distal-less homeobox gene 5a 0.876
atoh1b atonal homolog 1b 0.869
mib mind bomb 0.859
fgf3 fibroblast growth factor 3 0.853
lhx1a LIM homeobox 1a 0.844
eng2b engrailed 2b 0.833
dlx6a distal-less homeobox gene 6a 0.831
dlx4a distal-less homeobox gene 4a 0.784
sox1a SRY-box containing gene 1a 0.763
neurod4 neurogenic differentiation 4 0.755
barhl2 BarH-like 2 0.742
ptf1a pancreas specific transcription factor, 1a 0.726
fgf8a fibroblast growth factor 8 a 0.706
sox9a SRY-box containing gene 9a 0.691
emx3 empty spiracles homeobox 3 0.675
notch1a notch homolog 1a 0.668
neurod neurogenic differentiation 0.666
cdh23 cadherin-like 23 0.658
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.657
irx1a iroquois homeobox protein 1, a 0.634
fgfr1a fibroblast growth factor receptor 1a 0.612
ascl1a achaete-scute complex-like 1a (Drosophila) 0.608
met met proto-oncogene (hepatocyte growth factor receptor) 0.598
dlx2a distal-less homeobox gene 2a 0.589
hmx3 homeo box (H6 family) 3 0.588
foxg1a forkhead box G1a 0.587
fzd8a frizzled homolog 8a 0.582
clrn1 clarin 1 0.573
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.554
rx3 retinal homeobox gene 3 0.540
pax6b paired box gene 6b 0.536
gpr126 G protein-coupled receptor 126 0.526
pax6a paired box gene 6a 0.520
foxn4 forkhead box N4 0.510
meis2.1 myeloid ecotropic viral integration site 2.1 0.493
sox3 SRY-box containing gene 3 0.466
shhb sonic hedgehog b 0.462
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.458
six3a sine oculis homeobox homolog 3a 0.456
gbx1 gastrulation brain homeobox 1 0.441
crabp2a cellular retinoic acid binding protein 2, a 0.429
tbx2b T-box 2b 0.428
her8a hairy-related 8a 0.421
ndr2 nodal-related 2 0.415
prox1 prospero-related homeobox gene 1 0.411
fgfr4 fibroblast growth factor receptor 4 0.410
traf4a tnf receptor-associated factor 4a 0.387
runx2a runt-related transcription factor 2a 0.365
her4.2 hairy-related 4.2 0.360
bdnf brain-derived neurotrophic factor 0.343
ift88 intraflagellar transport 88 homolog 0.342
fezf2 FEZ family zinc finger 2 0.337
sncb synuclein, beta 0.336
bmp4 bone morphogenetic protein 4 0.336
igfbp3 insulin-like growth factor binding protein 3 0.320
hhip hedgehog interacting protein 0.310
irx4b iroquois homeobox protein 4b 0.306
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.294
bmp2b bone morphogenetic protein 2b 0.290
prdm1a PR domain containing 1a, with ZNF domain 0.287
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.286
nr2f2 nuclear receptor subfamily 2, group F, member 2 0.285
insm1b insulinoma-associated 1b 0.281
fgf4 fibroblast growth factor 4 0.275
zic4 zic family member 4 0.272
nkx2.2a NK2 transcription factor related 2a 0.268
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.267
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.263
sulf2 sulfatase 2 0.252
six4b sine oculis homeobox homolog 4b 0.250
elavl3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) 0.235
cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 0.222
jag1b jagged 1b 0.216
dlx2b distal-less homeobox gene 2b 0.212
fsta follistatin a 0.211
otx2 orthodenticle homolog 2 0.206
notch3 notch homolog 3 0.199
pcdh17 protocadherin 17 0.195
kitb kit receptor b 0.194
pou3f1 POU class 3 homeobox 1 0.185
pcdh8 protocadherin 8 0.184
insm1a insulinoma-associated 1a 0.182
eomesa eomesodermin homolog a 0.182
atp6v1ba ATPase, H+ transporting, lysosomal, V1 subunit B, member a 0.181
sall4 sal-like 4 (Drosophila) 0.177
otx1b orthodenticle homolog 1b 0.173
pitx2 paired-like homeodomain transcription factor 2 0.168
ush1c Usher syndrome 1C (autosomal recessive, severe) 0.168
cc2d2a coiled-coil and C2 domain containing 2A 0.167
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Epha5 EphA5 0.248
Tpm4 tropomyosin 4 0.228
Cox8a cytochrome c oxidase subunit VIIIa 0.213
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.144
Myh9 myosin, heavy chain 9, non-muscle 0.115
Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 0.095
Bbx bobby sox homolog (Drosophila) 0.094
Map2 microtubule-associated protein 2 0.089
Jak1 Janus kinase 1 0.087
Dynlrb1 dynein light chain roadblock-type 1 0.085
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.081
Ece1 endothelin converting enzyme 1 0.076
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.071
Unc5b unc-5 homolog B (C. elegans) 0.066
Myo1c myosin IC 0.064
Vax1 ventral anterior homeobox 1 0.063
Rara retinoic acid receptor, alpha 0.062
Nrxn3 neurexin 3 0.055
B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 0.055
Mcam melanoma cell adhesion molecule 0.054
Picalm phosphatidylinositol binding clathrin assembly protein 0.052
Kcnh6 potassium voltage-gated channel, subfamily H (eag-related), member 6 0.052
Scn3a sodium channel, voltage-gated, type III, alpha 0.051
Myt1l myelin transcription factor 1-like 0.049
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.049
Acvr1 activin A receptor, type I 0.049
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.047
Atp2b3 ATPase, Ca++ transporting, plasma membrane 3 0.047
Arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.044
Fgf22 fibroblast growth factor 22 0.044
Nos3 nitric oxide synthase 3, endothelial cell 0.044
Mprip myosin phosphatase Rho interacting protein 0.044
Cnksr2 connector enhancer of kinase suppressor of Ras 2 0.043
Agrn agrin 0.043
RGD1565772 similar to hypothetical protein A430110N23 0.042
Sdc2 syndecan 2 0.042
Pcsk2 proprotein convertase subtilisin/kexin type 2 0.041
St13 suppression of tumorigenicity 13 0.041
Kcnn2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 0.041
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.041
Dll3 delta-like 3 (Drosophila) 0.041
Igf2r insulin-like growth factor 2 receptor 0.040
Kcnd2 potassium voltage-gated channel, Shal-related subfamily, member 2 0.040
Slc12a4 solute carrier family 12 (potassium/chloride transporters), member 4 0.040
Kcnc1 potassium voltage gated channel, Shaw-related subfamily, member 1 0.039
Il4ra interleukin 4 receptor, alpha 0.039
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.039
Tgfb3 transforming growth factor, beta 3 0.039
Sox10 SRY (sex determining region Y)-box 10 0.039
Dnajc6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.039
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.038
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.038
Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.038
Pak3 p21 protein (Cdc42/Rac)-activated kinase 3 0.038
Mospd4 motile sperm domain containing 4 0.038
Notch1 Notch homolog 1, translocation-associated (Drosophila) 0.037
Nfia nuclear factor I/A 0.037
Rhbdf1 rhomboid 5 homolog 1 (Drosophila) 0.037
Amh anti-Mullerian hormone 0.036
Khsrp KH-type splicing regulatory protein 0.036
Cep164 centrosomal protein 164 0.036
Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 0.035
Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 0.035
Tgfbr2 transforming growth factor, beta receptor II 0.035
Car7 carbonic anhydrase 7 0.035
Sox13 SRY (sex determining region Y)-box 13 0.035
Nrarp Notch-regulated ankyrin repeat protein 0.035
Emp1 epithelial membrane protein 1 0.034
Epn2 epsin 2 0.034
Acvr2b activin A receptor, type IIB 0.034
Znf76 zinc finger protein 76 (expressed in testis) 0.034
Mapk3 mitogen activated protein kinase 3 0.033
Smad1 SMAD family member 1 0.032
Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) 0.032
Nr4a2 nuclear receptor subfamily 4, group A, member 2 0.032
Gtf2ird1 GTF2I repeat domain containing 1 0.032
Nckap1 NCK-associated protein 1 0.032
Tcf4 transcription factor 4 0.032
LOC682967 similar to Protein disulfide-isomerase TXNDC10 precursor (Thioredoxin domain-containing protein 10) 0.032
Ddn dendrin 0.031
Il6st interleukin 6 signal transducer 0.031
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.031
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.031
RGD1561672 similar to novel protein 0.031
Ppp1r10 protein phosphatase 1, regulatory subunit 10 0.031
Cald1 caldesmon 1 0.030
Gja1 gap junction protein, alpha 1 0.030
Lamc1 laminin, gamma 1 0.030
Pou3f3 POU class 3 homeobox 3 0.030
Smad7 SMAD family member 7 0.030
Gabra4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.030
Crygc crystallin, gamma C 0.030
Mllt6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 0.029
Chrm3 cholinergic receptor, muscarinic 3 0.029
Cbln2 cerebellin 2 precursor 0.029
Dtx3l deltex 3-like (Drosophila) 0.029
Mgst3 microsomal glutathione S-transferase 3 0.028
Cercam cerebral endothelial cell adhesion molecule 0.028
Abcb9 ATP-binding cassette, subfamily B (MDR/TAP), member 9 0.028
Snap91 synaptosomal-associated protein 91 0.028
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism