IMP

Process View

Homo sapiens

30 genes annotated in human

regulation of establishment of protein localization to plasma membrane

Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of establishment of protein localization to plasma membrane"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of establishment of protein localization to plasma membrane" (in gray)

Name	Description	Probability	Func Analog Organism
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	1.000
FHL2	four and a half LIM domains 2	0.978
BCL2	B-cell CLL/lymphoma 2	0.887	Human
SNAP23	synaptosomal-associated protein, 23kDa	0.542
FYN	FYN oncogene related to SRC, FGR, YES	0.525
SORBS3	sorbin and SH3 domain containing 3	0.310
GDA	guanine deaminase	0.251
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.246	Human
PXN	paxillin	0.240
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.240
FN1	fibronectin 1	0.232
BCL2L1	BCL2-like 1	0.204
PTPRC	protein tyrosine phosphatase, receptor type, C	0.191
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.190
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.150
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.145
BAD	BCL2-associated agonist of cell death	0.140
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.135
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.131
SNAP25	synaptosomal-associated protein, 25kDa	0.124
PDIA3	protein disulfide isomerase family A, member 3	0.113
SFN	stratifin	0.109
FLNA	filamin A, alpha	0.106
PSEN2	presenilin 2 (Alzheimer disease 4)	0.102
BAK1	BCL2-antagonist/killer 1	0.091	Human
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.088
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.087
NOXA1	NADPH oxidase activator 1	0.086
EPS8	epidermal growth factor receptor pathway substrate 8	0.083
IER3	immediate early response 3	0.072
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.071
RAB22A	RAB22A, member RAS oncogene family	0.070
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.070
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.070
BAX	BCL2-associated X protein	0.070	Human
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.065
STX6	syntaxin 6	0.063
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.060	Human
ADAM17	ADAM metallopeptidase domain 17	0.060
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.056
ENG	endoglin	0.055
CYTH1	cytohesin 1	0.055
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.053
USP8	ubiquitin specific peptidase 8	0.051
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.050
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.048	Human
ITGB4	integrin, beta 4	0.048	Human
LCK	lymphocyte-specific protein tyrosine kinase	0.048
EFNA1	ephrin-A1	0.048
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.046
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.044	Human
NEK9	NIMA (never in mitosis gene a)- related kinase 9	0.043
GRB7	growth factor receptor-bound protein 7	0.041
RAB5A	RAB5A, member RAS oncogene family	0.041
PFN1	profilin 1	0.038
ILK	integrin-linked kinase	0.038
MYO10	myosin X	0.036
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.033
EFNA5	ephrin-A5	0.033
RANBP9	RAN binding protein 9	0.033
ZNF746	zinc finger protein 746	0.033
FLNB	filamin B, beta	0.033
CARD11	caspase recruitment domain family, member 11	0.032
CDCP1	CUB domain containing protein 1	0.032
SYK	spleen tyrosine kinase	0.031
GRB10	growth factor receptor-bound protein 10	0.031
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.031
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.029
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.028
NCF4	neutrophil cytosolic factor 4, 40kDa	0.028
STX12	syntaxin 12	0.027
PTCH1	patched 1	0.026
EPS15	epidermal growth factor receptor pathway substrate 15	0.026
PRKCB	protein kinase C, beta	0.026
PICK1	protein interacting with PRKCA 1	0.025
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.025
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.025
AGTPBP1	ATP/GTP binding protein 1	0.025
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.024	Human
RDX	radixin	0.024
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.024
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.024
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.023
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.023
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.023
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.023
DLG4	discs, large homolog 4 (Drosophila)	0.023	Human
STK10	serine/threonine kinase 10	0.022
APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	0.021	Human
CTGF	connective tissue growth factor	0.021
CD9	CD9 molecule	0.021
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.020
RAB11FIP2	RAB11 family interacting protein 2 (class I)	0.020
TLN1	talin 1	0.020
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.020	Human
MSN	moesin	0.020
CD63	CD63 molecule	0.020
SPAG9	sperm associated antigen 9	0.020
VCL	vinculin	0.020
SH3RF1	SH3 domain containing ring finger 1	0.019
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.019
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.019
TSC22D4	TSC22 domain family, member 4	0.018
MAPK1	mitogen-activated protein kinase 1	0.017
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.017
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.017
VCAM1	vascular cell adhesion molecule 1	0.017
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.017
ITSN1	intersectin 1 (SH3 domain protein)	0.017
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.017
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.017
ITGA6	integrin, alpha 6	0.016	Human
EPHA7	EPH receptor A7	0.016	Human
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.016
RHOC	ras homolog gene family, member C	0.016
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.016
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.016
MAPT	microtubule-associated protein tau	0.016
STX4	syntaxin 4	0.016
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.016
DGCR14	DiGeorge syndrome critical region gene 14	0.015
OXSR1	oxidative-stress responsive 1	0.015
DEF6	differentially expressed in FDCP 6 homolog (mouse)	0.015
COL17A1	collagen, type XVII, alpha 1	0.015
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.015
JUP	junction plakoglobin	0.015
HSPG2	heparan sulfate proteoglycan 2	0.015
LAMC2	laminin, gamma 2	0.015
CD97	CD97 molecule	0.015
CD46	CD46 molecule, complement regulatory protein	0.015
NCK1	NCK adaptor protein 1	0.015
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.014
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.014
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.014	Human
PICALM	phosphatidylinositol binding clathrin assembly protein	0.014
YAP1	Yes-associated protein 1	0.014
ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	0.014
ADAM10	ADAM metallopeptidase domain 10	0.014
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.014	Human
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.014
EPHA3	EPH receptor A3	0.014	Human
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.014
MYO16	myosin XVI	0.013
TMC6	transmembrane channel-like 6	0.013
EML2	echinoderm microtubule associated protein like 2	0.013
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.013
CORO1A	coronin, actin binding protein, 1A	0.013
SCAMP1	secretory carrier membrane protein 1	0.013
EFHD2	EF-hand domain family, member D2	0.013
GSK3B	glycogen synthase kinase 3 beta	0.013
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.013
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.013
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.013
VHL	von Hippel-Lindau tumor suppressor	0.012
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.012
MYO1C	myosin IC	0.012
VAMP8	vesicle-associated membrane protein 8 (endobrevin)	0.012
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.012
MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	0.012
TSG101	tumor susceptibility gene 101	0.012
ELF4	E74-like factor 4 (ets domain transcription factor)	0.012
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.012
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.012
C1orf93	chromosome 1 open reading frame 93	0.012
TP53BP2	tumor protein p53 binding protein, 2	0.012
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.012	Human
RNF144B	ring finger protein 144B	0.012
SNX9	sorting nexin 9	0.011
ICAM3	intercellular adhesion molecule 3	0.011
CCNK	cyclin K	0.011
RNR2	l-rRNA	0.011
ZC3HC1	zinc finger, C3HC-type containing 1	0.011
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.011
AHNAK	AHNAK nucleoprotein	0.011
STON2	stonin 2	0.011
BCL10	B-cell CLL/lymphoma 10	0.011
PRKCZ	protein kinase C, zeta	0.011	Human
PDLIM5	PDZ and LIM domain 5	0.011
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.011	Human
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.011
EPHB3	EPH receptor B3	0.011	Human
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.011
DZIP1	DAZ interacting protein 1	0.011
LAMB3	laminin, beta 3	0.011
PKP3	plakophilin 3	0.011
BID	BH3 interacting domain death agonist	0.011
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.011
CEP70	centrosomal protein 70kDa	0.011
GLIS2	GLIS family zinc finger 2	0.011
EHD1	EH-domain containing 1	0.011
RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	0.011
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.011
AGFG1	ArfGAP with FG repeats 1	0.011
RAB11FIP3	RAB11 family interacting protein 3 (class II)	0.011
EZR	ezrin	0.010
EPHA2	EPH receptor A2	0.010
ADIPOR1	adiponectin receptor 1	0.010
KIAA0930	KIAA0930	0.010
TRAF5	TNF receptor-associated factor 5	0.010
SCAMP2	secretory carrier membrane protein 2	0.010
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.010
DTNB	dystrobrevin, beta	0.010
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.010
DBN1	drebrin 1	0.010
ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A	0.010
MBNL1	muscleblind-like (Drosophila)	0.010
ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)	0.010
ERC2	ELKS/RAB6-interacting/CAST family member 2	0.010
MAPK9	mitogen-activated protein kinase 9	0.010
TGFA	transforming growth factor, alpha	0.010