IMP
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positive regulation of rho protein signal transduction
Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of rho protein signal transduction"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| ARRB1 | arrestin, beta 1 | 0.932 | ||
| IGF1R | insulin-like growth factor 1 receptor | 0.892 | ||
| RHOA | ras homolog gene family, member A | 0.807 | ||
| ARRB2 | arrestin, beta 2 | 0.798 | Human | |
| HP | haptoglobin | 0.789 | ||
| ZNF496 | zinc finger protein 496 | 0.739 | ||
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.732 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.716 | ||
| A2M | alpha-2-macroglobulin | 0.674 | ||
| MAPK10 | mitogen-activated protein kinase 10 | 0.528 | ||
| GNMT | glycine N-methyltransferase | 0.436 | ||
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.417 | ||
| APOC1 | apolipoprotein C-I | 0.412 | ||
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.347 | ||
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.328 | ||
| ARHGAP1 | Rho GTPase activating protein 1 | 0.233 | ||
| NAV1 | neuron navigator 1 | 0.216 | ||
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.207 | ||
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.202 | ||
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | 0.177 | ||
| LCAT | lecithin-cholesterol acyltransferase | 0.176 | ||
| CSNK1E | casein kinase 1, epsilon | 0.128 | ||
| COL1A2 | collagen, type I, alpha 2 | 0.121 | ||
| AKT1S1 | AKT1 substrate 1 (proline-rich) | 0.118 | ||
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.104 | Fly | |
| HIST2H2AB | histone cluster 2, H2ab | 0.097 | ||
| ALB | albumin | 0.094 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.090 | ||
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.087 | ||
| TTR | transthyretin | 0.084 | ||
| GNAS | GNAS complex locus | 0.082 | ||
| APOA1 | apolipoprotein A-I | 0.080 | ||
| APOC3 | apolipoprotein C-III | 0.079 | ||
| RAB5C | RAB5C, member RAS oncogene family | 0.070 | ||
| MYO9B | myosin IXB | 0.064 | ||
| STMN2 | stathmin-like 2 | 0.063 | ||
| DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.060 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.060 | ||
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.059 | Fly | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.058 | ||
| DISC1 | disrupted in schizophrenia 1 | 0.054 | ||
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.052 | ||
| YY1 | YY1 transcription factor | 0.049 | ||
| APOA2 | apolipoprotein A-II | 0.047 | ||
| DCN | decorin | 0.047 | ||
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.047 | ||
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.047 | ||
| LOX | lysyl oxidase | 0.045 | ||
| PRR5 | proline rich 5 (renal) | 0.044 | ||
| APOC2 | apolipoprotein C-II | 0.044 | ||
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.043 | ||
| RHEBL1 | Ras homolog enriched in brain like 1 | 0.041 | ||
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.039 | ||
| INADL | InaD-like (Drosophila) | 0.038 | ||
| CFL1 | cofilin 1 (non-muscle) | 0.037 | ||
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.036 | ||
| POSTN | periostin, osteoblast specific factor | 0.036 | ||
| COL1A1 | collagen, type I, alpha 1 | 0.036 | ||
| RHEB | Ras homolog enriched in brain | 0.035 | ||
| NEK6 | NIMA (never in mitosis gene a)-related kinase 6 | 0.034 | ||
| PRR5L | proline rich 5 like | 0.034 | ||
| MPRIP | myosin phosphatase Rho interacting protein | 0.033 | ||
| NGF | nerve growth factor (beta polypeptide) | 0.032 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.030 | ||
| PTAFR | platelet-activating factor receptor | 0.029 | ||
| AGTR1 | angiotensin II receptor, type 1 | 0.029 | ||
| SDC3 | syndecan 3 | 0.028 | ||
| TXNDC2 | thioredoxin domain containing 2 (spermatozoa) | 0.028 | ||
| COL5A2 | collagen, type V, alpha 2 | 0.027 | ||
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 0.025 | ||
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta | 0.025 | ||
| SALL2 | sal-like 2 (Drosophila) | 0.025 | ||
| PROCR | protein C receptor, endothelial | 0.025 | ||
| DIAPH1 | diaphanous homolog 1 (Drosophila) | 0.024 | ||
| RRAGD | Ras-related GTP binding D | 0.024 | ||
| FASN | fatty acid synthase | 0.024 | ||
| MAPK9 | mitogen-activated protein kinase 9 | 0.023 | ||
| TAOK1 | TAO kinase 1 | 0.023 | ||
| PLTP | phospholipid transfer protein | 0.023 | ||
| PTPN5 | protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) | 0.023 | ||
| RTKN | rhotekin | 0.022 | ||
| CAV2 | caveolin 2 | 0.022 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.022 | ||
| STK38 | serine/threonine kinase 38 | 0.021 | ||
| MAP2K7 | mitogen-activated protein kinase kinase 7 | 0.021 | ||
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.021 | ||
| HIPK3 | homeodomain interacting protein kinase 3 | 0.021 | ||
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.020 | ||
| LOXL4 | lysyl oxidase-like 4 | 0.020 | ||
| SPRR2A | small proline-rich protein 2A | 0.020 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.019 | ||
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.019 | ||
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.019 | ||
| PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.019 | ||
| LIMK1 | LIM domain kinase 1 | 0.019 | ||
| COL5A1 | collagen, type V, alpha 1 | 0.018 | ||
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.018 | ||
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 | 0.018 | ||
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.018 | ||
| MCC | mutated in colorectal cancers | 0.018 | ||
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.018 | ||
| SNCAIP | synuclein, alpha interacting protein | 0.017 | ||
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.017 | ||
| FAM83C | family with sequence similarity 83, member C | 0.016 | ||
| MAPK14 | mitogen-activated protein kinase 14 | 0.016 | ||
| FAM110A | family with sequence similarity 110, member A | 0.016 | ||
| YAF2 | YY1 associated factor 2 | 0.016 | ||
| HMGXB3 | HMG box domain containing 3 | 0.016 | ||
| DGKZ | diacylglycerol kinase, zeta | 0.016 | ||
| COL6A1 | collagen, type VI, alpha 1 | 0.016 | ||
| ADRB2 | adrenergic, beta-2-, receptor, surface | 0.015 | ||
| CLEC4G | C-type lectin domain family 4, member G | 0.015 | ||
| FAM110C | family with sequence similarity 110, member C | 0.015 | ||
| RCOR2 | REST corepressor 2 | 0.015 | ||
| RPL11 | ribosomal protein L11 | 0.015 | ||
| TMCC2 | transmembrane and coiled-coil domain family 2 | 0.015 | ||
| C7orf25 | chromosome 7 open reading frame 25 | 0.015 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.015 | ||
| INO80 | INO80 homolog (S. cerevisiae) | 0.015 | ||
| HES1 | hairy and enhancer of split 1, (Drosophila) | 0.014 | ||
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.014 | ||
| KIF26A | kinesin family member 26A | 0.014 | ||
| CCL14 | chemokine (C-C motif) ligand 14 | 0.014 | ||
| APOE | apolipoprotein E | 0.014 | Human | |
| MT1A | metallothionein 1A | 0.014 | ||
| USP4 | ubiquitin specific peptidase 4 (proto-oncogene) | 0.014 | ||
| H1FX | H1 histone family, member X | 0.014 | ||
| SPEF2 | sperm flagellar 2 | 0.014 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.014 | ||
| OLFML2B | olfactomedin-like 2B | 0.014 | ||
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.014 | ||
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) | 0.014 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.013 | ||
| APOB | apolipoprotein B (including Ag(x) antigen) | 0.013 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.013 | ||
| LARS | leucyl-tRNA synthetase | 0.013 | ||
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.013 | ||
| STK4 | serine/threonine kinase 4 | 0.013 | ||
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.013 | ||
| OLFML3 | olfactomedin-like 3 | 0.013 | ||
| PTEN | phosphatase and tensin homolog | 0.013 | ||
| NOS3 | nitric oxide synthase 3 (endothelial cell) | 0.013 | ||
| GSN | gelsolin | 0.013 | ||
| ARHGAP4 | Rho GTPase activating protein 4 | 0.013 | ||
| KLHL5 | kelch-like 5 (Drosophila) | 0.013 | ||
| DNTT | deoxynucleotidyltransferase, terminal | 0.012 | ||
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.012 | ||
| FAP | fibroblast activation protein, alpha | 0.012 | ||
| TF | transferrin | 0.012 | ||
| GRB10 | growth factor receptor-bound protein 10 | 0.012 | ||
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 | 0.012 | ||
| ASPN | asporin | 0.012 | ||
| CDK3 | cyclin-dependent kinase 3 | 0.012 | ||
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.012 | ||
| ITGB7 | integrin, beta 7 | 0.012 | ||
| ARR3 | arrestin 3, retinal (X-arrestin) | 0.012 | Human | |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.012 | ||
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.012 | ||
| SH3BP1 | SH3-domain binding protein 1 | 0.012 | ||
| SMN1 | survival of motor neuron 1, telomeric | 0.011 | ||
| COL6A3 | collagen, type VI, alpha 3 | 0.011 | ||
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.011 | ||
| MXRA5 | matrix-remodelling associated 5 | 0.011 | ||
| P2RY10 | purinergic receptor P2Y, G-protein coupled, 10 | 0.011 | ||
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.011 | ||
| GMIP | GEM interacting protein | 0.011 | ||
| OSTF1 | osteoclast stimulating factor 1 | 0.011 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.011 | ||
| MPP1 | membrane protein, palmitoylated 1, 55kDa | 0.011 | ||
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | 0.011 | ||
| ZBTB25 | zinc finger and BTB domain containing 25 | 0.011 | ||
| TTI1 | Tel2 interacting protein 1 homolog (S. pombe) | 0.011 | ||
| FCHO1 | FCH domain only 1 | 0.011 | ||
| RHO | rhodopsin | 0.011 | ||
| FAM129A | family with sequence similarity 129, member A | 0.011 | ||
| CSAD | cysteine sulfinic acid decarboxylase | 0.011 | ||
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.011 | ||
| PHKA2 | phosphorylase kinase, alpha 2 (liver) | 0.011 | ||
| PLD2 | phospholipase D2 | 0.011 | ||
| DGKA | diacylglycerol kinase, alpha 80kDa | 0.011 | ||
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.011 | ||
| A1BG | alpha-1-B glycoprotein | 0.011 | ||
| LDLR | low density lipoprotein receptor | 0.011 | ||
| RARA | retinoic acid receptor, alpha | 0.011 | ||
| SEMA5B | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B | 0.011 | ||
| MAST1 | microtubule associated serine/threonine kinase 1 | 0.011 | ||
| EDNRA | endothelin receptor type A | 0.011 | ||
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.010 | ||
| CCNDBP1 | cyclin D-type binding-protein 1 | 0.010 | ||
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.010 | ||
| PLXNA3 | plexin A3 | 0.010 | ||
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.010 | ||
| BGN | biglycan | 0.010 | ||
| MLL4 | myeloid/lymphoid or mixed-lineage leukemia 4 | 0.010 | ||
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.010 | ||
| CP | ceruloplasmin (ferroxidase) | 0.010 | ||
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.010 | ||
| COL4A5 | collagen, type IV, alpha 5 | 0.010 | ||
| WDR73 | WD repeat domain 73 | 0.010 | ||
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) | 0.010 | ||
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.010 | ||
| SERPINA10 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | 0.010 | ||
| LSM11 | LSM11, U7 small nuclear RNA associated | 0.010 | ||
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.010 |