IMP

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of osteoclast differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of osteoclast differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
TRAF1	TNF receptor-associated factor 1	1.000	Human
CCR5	chemokine (C-C motif) receptor 5	0.997	Human
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.967
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.966
CCL5	chemokine (C-C motif) ligand 5	0.926	Rat
TRAF2	TNF receptor-associated factor 2	0.877	Human
TRAF3	TNF receptor-associated factor 3	0.856	Human
CD40	CD40 molecule, TNF receptor superfamily member 5	0.764
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.650
BIRC3	baculoviral IAP repeat containing 3	0.633
CFLAR	CASP8 and FADD-like apoptosis regulator	0.562
FAS	Fas (TNF receptor superfamily, member 6)	0.541
CCR2	chemokine (C-C motif) receptor 2	0.458	Human
CCL4	chemokine (C-C motif) ligand 4	0.431
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.413
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.413
TRADD	TNFRSF1A-associated via death domain	0.386
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.379
IL2RB	interleukin 2 receptor, beta	0.356
CCL22	chemokine (C-C motif) ligand 22	0.325
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.294
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.238
RIPK2	receptor-interacting serine-threonine kinase 2	0.191
CXCL9	chemokine (C-X-C motif) ligand 9	0.186
IRF4	interferon regulatory factor 4	0.166
TNF	tumor necrosis factor	0.165
CXCR6	chemokine (C-X-C motif) receptor 6	0.129	Human
CD2	CD2 molecule	0.120
CCR4	chemokine (C-C motif) receptor 4	0.114	Human
FASLG	Fas ligand (TNF superfamily, member 6)	0.108	Human
TRAF5	TNF receptor-associated factor 5	0.106	Human
JUN	jun proto-oncogene	0.105
IFNG	interferon, gamma	0.098
CD40LG	CD40 ligand	0.092
CCR7	chemokine (C-C motif) receptor 7	0.084	Human
ZNF512B	zinc finger protein 512B	0.081
CXCR3	chemokine (C-X-C motif) receptor 3	0.078	Human
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.075
TRAF6	TNF receptor-associated factor 6	0.069
IDE	insulin-degrading enzyme	0.068
CCL7	chemokine (C-C motif) ligand 7	0.056
IL10RA	interleukin 10 receptor, alpha	0.054
SH2D1A	SH2 domain containing 1A	0.052
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.052
NUMBL	numb homolog (Drosophila)-like	0.046
JUND	jun D proto-oncogene	0.044
ATF3	activating transcription factor 3	0.042
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.042
NOTCH2NL	notch 2 N-terminal like	0.040
FADD	Fas (TNFRSF6)-associated via death domain	0.040
ING2	inhibitor of growth family, member 2	0.037
ITK	IL2-inducible T-cell kinase	0.037
CD6	CD6 molecule	0.035
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.033
CCL11	chemokine (C-C motif) ligand 11	0.032
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.032
CXCL10	chemokine (C-X-C motif) ligand 10	0.031
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.030
CCL3	chemokine (C-C motif) ligand 3	0.030	Rat
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.028
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.026
CXCL11	chemokine (C-X-C motif) ligand 11	0.026
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.025
CCL8	chemokine (C-C motif) ligand 8	0.024
TANK	TRAF family member-associated NFKB activator	0.022
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.022
JAG1	jagged 1	0.021
SLAMF7	SLAM family member 7	0.020
XIAP	X-linked inhibitor of apoptosis	0.020
JUNB	jun B proto-oncogene	0.020
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.020
IL2RG	interleukin 2 receptor, gamma	0.018
BIRC2	baculoviral IAP repeat containing 2	0.018
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.018
CXCL13	chemokine (C-X-C motif) ligand 13	0.018
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.018
IL7R	interleukin 7 receptor	0.017
CLEC7A	C-type lectin domain family 7, member A	0.017
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.016
DPP4	dipeptidyl-peptidase 4	0.016
TRAF3IP2	TRAF3 interacting protein 2	0.016
IL1B	interleukin 1, beta	0.016
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.016
IL21R	interleukin 21 receptor	0.015
CXCR5	chemokine (C-X-C motif) receptor 5	0.015	Human
C1orf93	chromosome 1 open reading frame 93	0.014
ZMYND11	zinc finger, MYND-type containing 11	0.014
BBS10	Bardet-Biedl syndrome 10	0.014
IER2	immediate early response 2	0.014
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	0.014
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.013
CCR1	chemokine (C-C motif) receptor 1	0.013
SMAD1	SMAD family member 1	0.013
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.013	Human
PELI3	pellino homolog 3 (Drosophila)	0.013
LAG3	lymphocyte-activation gene 3	0.012
IL4	interleukin 4	0.012
IL18RAP	interleukin 18 receptor accessory protein	0.012
CCL19	chemokine (C-C motif) ligand 19	0.012
CCR6	chemokine (C-C motif) receptor 6	0.012	Human
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.012
GPR171	G protein-coupled receptor 171	0.011
SGK1	serum/glucocorticoid regulated kinase 1	0.011
IL1A	interleukin 1, alpha	0.010
CCR8	chemokine (C-C motif) receptor 8	0.010	Human
GRAP2	GRB2-related adaptor protein 2	0.010
IL2RA	interleukin 2 receptor, alpha	0.010
LGALS2	lectin, galactoside-binding, soluble, 2	0.010