IMP

Process View

Homo sapiens

20 genes annotated in human

positive regulation of calcium ion transport into cytosol

Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of calcium ion transport into cytosol"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of calcium ion transport into cytosol" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000	Human
IL8	interleukin 8	0.999	Human
CCL5	chemokine (C-C motif) ligand 5	0.998	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.994	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.994	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.978	Human
CCL4	chemokine (C-C motif) ligand 4	0.977	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.977
CCL20	chemokine (C-C motif) ligand 20	0.917	Human
CXCL10	chemokine (C-X-C motif) ligand 10	0.912
CXCL11	chemokine (C-X-C motif) ligand 11	0.876
CCR7	chemokine (C-C motif) receptor 7	0.853	Human
CCL8	chemokine (C-C motif) ligand 8	0.839	Human
DPP4	dipeptidyl-peptidase 4	0.827
CCL22	chemokine (C-C motif) ligand 22	0.811	Human
CCL2	chemokine (C-C motif) ligand 2	0.791	Human
IFNG	interferon, gamma	0.731
IL6	interleukin 6 (interferon, beta 2)	0.709
IL1B	interleukin 1, beta	0.673
CXCL5	chemokine (C-X-C motif) ligand 5	0.657	Human
CCL19	chemokine (C-C motif) ligand 19	0.609	Human
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.570
CCR4	chemokine (C-C motif) receptor 4	0.568	Human
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.502
PTEN	phosphatase and tensin homolog	0.453
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.451	Human
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.421
CCL7	chemokine (C-C motif) ligand 7	0.417	Human
CCL3	chemokine (C-C motif) ligand 3	0.355	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.331
PSEN2	presenilin 2 (Alzheimer disease 4)	0.300
IL2RB	interleukin 2 receptor, beta	0.291
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.288
LAT	linker for activation of T cells	0.269
BAK1	BCL2-antagonist/killer 1	0.259
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.259
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.257
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.256	Human
CCR2	chemokine (C-C motif) receptor 2	0.243	Human
MPDZ	multiple PDZ domain protein	0.237
CCR3	chemokine (C-C motif) receptor 3	0.224	Human
GRB2	growth factor receptor-bound protein 2	0.206
CCL13	chemokine (C-C motif) ligand 13	0.194	Human
ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	0.178
TTN	titin	0.176
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.170
CXCR6	chemokine (C-X-C motif) receptor 6	0.160	Human
RNR2	l-rRNA	0.158
CCL11	chemokine (C-C motif) ligand 11	0.150	Human
RGS1	regulator of G-protein signaling 1	0.142
CAV2	caveolin 2	0.141
IRF4	interferon regulatory factor 4	0.124
BCL2L1	BCL2-like 1	0.123
TLR2	toll-like receptor 2	0.119
IL10RA	interleukin 10 receptor, alpha	0.113
TNF	tumor necrosis factor	0.109
CD22	CD22 molecule	0.107
SLAMF7	SLAM family member 7	0.100
CXCR3	chemokine (C-X-C motif) receptor 3	0.094
CLEC7A	C-type lectin domain family 7, member A	0.087
MAPT	microtubule-associated protein tau	0.087
AQP9	aquaporin 9	0.080
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.079
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.065
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.062
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.062
SELE	selectin E	0.062
IL7R	interleukin 7 receptor	0.059
UBD	ubiquitin D	0.059
IDE	insulin-degrading enzyme	0.059
LAMP3	lysosomal-associated membrane protein 3	0.059
CD83	CD83 molecule	0.058
CCR1	chemokine (C-C motif) receptor 1	0.056	Human
CD40LG	CD40 ligand	0.056
IL18RAP	interleukin 18 receptor accessory protein	0.055
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.053
SELL	selectin L	0.053
IDO1	indoleamine 2,3-dioxygenase 1	0.053
CD69	CD69 molecule	0.052
CH25H	cholesterol 25-hydroxylase	0.052
IL2RG	interleukin 2 receptor, gamma	0.050
ICAM1	intercellular adhesion molecule 1	0.050
CXCR2	chemokine (C-X-C motif) receptor 2	0.049	Human
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.049
CD86	CD86 molecule	0.048
ADAMDEC1	ADAM-like, decysin 1	0.046
IL1A	interleukin 1, alpha	0.046
ARRB1	arrestin, beta 1	0.046
BCL2A1	BCL2-related protein A1	0.044
IL10	interleukin 10	0.043
GZMK	granzyme K (granzyme 3; tryptase II)	0.042
SPTBN1	spectrin, beta, non-erythrocytic 1	0.041
PLEK	pleckstrin	0.041
CD2	CD2 molecule	0.041
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.040
GPR171	G protein-coupled receptor 171	0.040
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.037
PF4V1	platelet factor 4 variant 1	0.037	Human
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.037
CD79A	CD79a molecule, immunoglobulin-associated alpha	0.037
RNF144B	ring finger protein 144B	0.037
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.036
TRPC3	transient receptor potential cation channel, subfamily C, member 3	0.035
IL1R2	interleukin 1 receptor, type II	0.035
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.035
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.034
IL21R	interleukin 21 receptor	0.033
DOCK7	dedicator of cytokinesis 7	0.032
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.032
ITK	IL2-inducible T-cell kinase	0.031
BID	BH3 interacting domain death agonist	0.030
STAT4	signal transducer and activator of transcription 4	0.030
CD80	CD80 molecule	0.030
WNT2	wingless-type MMTV integration site family member 2	0.029
CCL23	chemokine (C-C motif) ligand 23	0.028	Human
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.028
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.028
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.028
FPR3	formyl peptide receptor 3	0.027
TFPI2	tissue factor pathway inhibitor 2	0.027
VCAM1	vascular cell adhesion molecule 1	0.027
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.026
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.026
CD160	CD160 molecule	0.026
BAD	BCL2-associated agonist of cell death	0.026
CD28	CD28 molecule	0.026
CXCR5	chemokine (C-X-C motif) receptor 5	0.025	Human
SNCAIP	synuclein, alpha interacting protein	0.025
FGA	fibrinogen alpha chain	0.025
SSTR3	somatostatin receptor 3	0.025
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.025
S100A12	S100 calcium binding protein A12	0.025
SOD2	superoxide dismutase 2, mitochondrial	0.024
CCR6	chemokine (C-C motif) receptor 6	0.024	Human
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.024
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.024
CARD11	caspase recruitment domain family, member 11	0.024
F3	coagulation factor III (thromboplastin, tissue factor)	0.023
CCL1	chemokine (C-C motif) ligand 1	0.023	Human
ASCC2	activating signal cointegrator 1 complex subunit 2	0.023
PTPRF	protein tyrosine phosphatase, receptor type, F	0.022
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.022
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.021
IL1F5	interleukin 1 family, member 5 (delta)	0.021
F2R	coagulation factor II (thrombin) receptor	0.021
CD48	CD48 molecule	0.021
SOCS3	suppressor of cytokine signaling 3	0.021
SPRR2A	small proline-rich protein 2A	0.021
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.021
CXCR4	chemokine (C-X-C motif) receptor 4	0.021	Human
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.021
CXCR1	chemokine (C-X-C motif) receptor 1	0.020	Human
TRPC6	transient receptor potential cation channel, subfamily C, member 6	0.020	Human
TAGAP	T-cell activation RhoGTPase activating protein	0.020
OASL	2'-5'-oligoadenylate synthetase-like	0.019
GPR109B	G protein-coupled receptor 109B	0.019
DLG4	discs, large homolog 4 (Drosophila)	0.019
ZFYVE9	zinc finger, FYVE domain containing 9	0.019
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.019
GPR65	G protein-coupled receptor 65	0.019
FLNB	filamin B, beta	0.018
SBF1	SET binding factor 1	0.018
CYTIP	cytohesin 1 interacting protein	0.018
CAV1	caveolin 1, caveolae protein, 22kDa	0.018	Mouse
DARC	Duffy blood group, chemokine receptor	0.018
CCR8	chemokine (C-C motif) receptor 8	0.018	Human
GIMAP4	GTPase, IMAP family member 4	0.018
C5AR1	complement component 5a receptor 1	0.017
PF4	platelet factor 4	0.017	Human
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.017
CSF3	colony stimulating factor 3 (granulocyte)	0.017
C2	complement component 2	0.017
C1orf93	chromosome 1 open reading frame 93	0.017
ACTN1	actinin, alpha 1	0.017
GPR183	G protein-coupled receptor 183	0.017
BCL2	B-cell CLL/lymphoma 2	0.016
IL6R	interleukin 6 receptor	0.016
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.016
CYBB	cytochrome b-245, beta polypeptide	0.016
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.016
CLC	Charcot-Leyden crystal protein	0.016
IGSF6	immunoglobulin superfamily, member 6	0.016
INADL	InaD-like (Drosophila)	0.016
ARRDC3	arrestin domain containing 3	0.016
NEB	nebulin	0.016
CD1B	CD1b molecule	0.016
ITPR3	inositol 1,4,5-trisphosphate receptor, type 3	0.016
IL1RN	interleukin 1 receptor antagonist	0.015
LAG3	lymphocyte-activation gene 3	0.015
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.015	Human
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.015
CCL17	chemokine (C-C motif) ligand 17	0.015	Human
ADORA3	adenosine A3 receptor	0.015
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.015	Human
TPM4	tropomyosin 4	0.015
TFEC	transcription factor EC	0.015
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.015
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.015
HTR4	5-hydroxytryptamine (serotonin) receptor 4	0.015	Human
MYL9	myosin, light chain 9, regulatory	0.015
ICOSLG	inducible T-cell co-stimulator ligand	0.015
SLAMF1	signaling lymphocytic activation molecule family member 1	0.015
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.015
RSAD2	radical S-adenosyl methionine domain containing 2	0.015
DNASE1L3	deoxyribonuclease I-like 3	0.015
F2RL3	coagulation factor II (thrombin) receptor-like 3	0.015
ALB	albumin	0.014
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.014
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.014
MUC1	mucin 1, cell surface associated	0.014
IL18R1	interleukin 18 receptor 1	0.014
CLEC5A	C-type lectin domain family 5, member A	0.014
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.014
MSH5	mutS homolog 5 (E. coli)	0.014
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.014
TRPC4	transient receptor potential cation channel, subfamily C, member 4	0.014	Human
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.014
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.013
XCL1	chemokine (C motif) ligand 1	0.013
CD72	CD72 molecule	0.013
TCL1A	T-cell leukemia/lymphoma 1A	0.013
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.013
NLRP3	NLR family, pyrin domain containing 3	0.013
SH3BP2	SH3-domain binding protein 2	0.013
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.013
CD1C	CD1c molecule	0.013
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.013
RNASE3	ribonuclease, RNase A family, 3	0.013
ADRB3	adrenergic, beta-3-, receptor	0.013	Human
CD79B	CD79b molecule, immunoglobulin-associated beta	0.013
ZP2	zona pellucida glycoprotein 2 (sperm receptor)	0.013
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.013
CCL21	chemokine (C-C motif) ligand 21	0.013
SIT1	signaling threshold regulating transmembrane adaptor 1	0.013
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.013
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.013
INHBA	inhibin, beta A	0.013
GHRHR	growth hormone releasing hormone receptor	0.013
HBG2	hemoglobin, gamma G	0.013
TBXA2R	thromboxane A2 receptor	0.013
IL13	interleukin 13	0.013
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.012
IPO11	importin 11	0.012
ODF1	outer dense fiber of sperm tails 1	0.012
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.012
BLK	B lymphoid tyrosine kinase	0.012
PROCR	protein C receptor, endothelial	0.012
BIRC3	baculoviral IAP repeat containing 3	0.012
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.012
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.012
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.012
TUB	tubby homolog (mouse)	0.012
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.012
CRP	C-reactive protein, pentraxin-related	0.011
PLXNA2	plexin A2	0.011
EDN1	endothelin 1	0.011
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.011
KYNU	kynureninase	0.011
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.011
ABO	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)	0.011
S1PR2	sphingosine-1-phosphate receptor 2	0.011
CD4	CD4 molecule	0.011
TBC1D10A	TBC1 domain family, member 10A	0.011
EGFL6	EGF-like-domain, multiple 6	0.011
CMIP	c-Maf-inducing protein	0.011
GP5	glycoprotein V (platelet)	0.011
OBSL1	obscurin-like 1	0.011
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.011
DSCAML1	Down syndrome cell adhesion molecule like 1	0.011
IL9	interleukin 9	0.011
FYN	FYN oncogene related to SRC, FGR, YES	0.011
CMKLR1	chemokine-like receptor 1	0.011
CCR9	chemokine (C-C motif) receptor 9	0.011	Human
ATP10A	ATPase, class V, type 10A	0.011
CD163	CD163 molecule	0.011
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.011
DRD1	dopamine receptor D1	0.010
PVRIG	poliovirus receptor related immunoglobulin domain containing	0.010
IL11	interleukin 11	0.010
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.010
BLNK	B-cell linker	0.010
C3AR1	complement component 3a receptor 1	0.010
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.010
FGFR1	fibroblast growth factor receptor 1	0.010
CLEC10A	C-type lectin domain family 10, member A	0.010
MOBKL2B	MOB1, Mps One Binder kinase activator-like 2B (yeast)	0.010
PRKCDBP	protein kinase C, delta binding protein	0.010
CHRNB4	cholinergic receptor, nicotinic, beta 4	0.010
OPRM1	opioid receptor, mu 1	0.010
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.010
IL3RA	interleukin 3 receptor, alpha (low affinity)	0.010
CXCL12	chemokine (C-X-C motif) ligand 12	0.010