IMP

Process View

Homo sapiens

26 genes annotated in human

positive regulation of oxidoreductase activity

Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of oxidoreductase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of oxidoreductase activity" (in gray)

Name	Description	Probability	Func Analog Organism
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.991
ESR1	estrogen receptor 1	0.980
HNF4A	hepatocyte nuclear factor 4, alpha	0.662
MAPT	microtubule-associated protein tau	0.609
IL1R1	interleukin 1 receptor, type I	0.521
BCAR1	breast cancer anti-estrogen resistance 1	0.366
IL1B	interleukin 1, beta	0.297
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.269
IL1R2	interleukin 1 receptor, type II	0.232
HP	haptoglobin	0.230
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.224
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.190	Human
MPDZ	multiple PDZ domain protein	0.190
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.188
PDZD11	PDZ domain containing 11	0.181
CDCP1	CUB domain containing protein 1	0.179
NOXA1	NADPH oxidase activator 1	0.152
PPP5C	protein phosphatase 5, catalytic subunit	0.152
DSG2	desmoglein 2	0.122
HR	hairless homolog (mouse)	0.119
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.117
A2M	alpha-2-macroglobulin	0.111
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.109
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.099
PPARG	peroxisome proliferator-activated receptor gamma	0.096	Human
RARA	retinoic acid receptor, alpha	0.093
IL1RAP	interleukin 1 receptor accessory protein	0.091
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.088
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.087
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.086
PSEN1	presenilin 1	0.085
IL1RN	interleukin 1 receptor antagonist	0.085	Human
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.083
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.079
SPRR2A	small proline-rich protein 2A	0.072
CHD9	chromodomain helicase DNA binding protein 9	0.070
IL8	interleukin 8	0.068
CTNND1	catenin (cadherin-associated protein), delta 1	0.067
NCOR2	nuclear receptor corepressor 2	0.066
CCL20	chemokine (C-C motif) ligand 20	0.062
PRKCZ	protein kinase C, zeta	0.062	Human
PICK1	protein interacting with PRKCA 1	0.058
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.058
MATK	megakaryocyte-associated tyrosine kinase	0.052
DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.047
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.046
APOA1	apolipoprotein A-I	0.045	Human
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.045
JUP	junction plakoglobin	0.044
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.043	Mouse
PDCD6IP	programmed cell death 6 interacting protein	0.042
PRKCB	protein kinase C, beta	0.042
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.039
BIRC3	baculoviral IAP repeat containing 3	0.038
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.038
MYLK2	myosin light chain kinase 2	0.037
EP300	E1A binding protein p300	0.037
PTEN	phosphatase and tensin homolog	0.035
ESRRG	estrogen-related receptor gamma	0.035	Human
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.035
SNCAIP	synuclein, alpha interacting protein	0.033
CXCL2	chemokine (C-X-C motif) ligand 2	0.032
PTPRA	protein tyrosine phosphatase, receptor type, A	0.031
TIMP3	TIMP metallopeptidase inhibitor 3	0.031
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.031
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.030
AR	androgen receptor	0.030
TGFA	transforming growth factor, alpha	0.030
SPTBN1	spectrin, beta, non-erythrocytic 1	0.030
ZNF71	zinc finger protein 71	0.029
SH3RF1	SH3 domain containing ring finger 1	0.029
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.029
HIPK2	homeodomain interacting protein kinase 2	0.029
LCAT	lecithin-cholesterol acyltransferase	0.028
APOC3	apolipoprotein C-III	0.028
CLEC4E	C-type lectin domain family 4, member E	0.028	Human
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.027
APP	amyloid beta (A4) precursor protein	0.026
SKIL	SKI-like oncogene	0.026
CXCL5	chemokine (C-X-C motif) ligand 5	0.026
DCTN1	dynactin 1	0.024
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.024
FYN	FYN oncogene related to SRC, FGR, YES	0.024
ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	0.023
SOD1	superoxide dismutase 1, soluble	0.023
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.023
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.022
APOC1	apolipoprotein C-I	0.022
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.022
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.022
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.021
CCL4	chemokine (C-C motif) ligand 4	0.021
SQSTM1	sequestosome 1	0.021
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.020
NUMB	numb homolog (Drosophila)	0.020
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.020
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.020
DSP	desmoplakin	0.020
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.020
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.019
ESR2	estrogen receptor 2 (ER beta)	0.019	Human
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.019
SH2D1A	SH2 domain containing 1A	0.019
AQP9	aquaporin 9	0.019
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.019
CCL22	chemokine (C-C motif) ligand 22	0.019
CXCL3	chemokine (C-X-C motif) ligand 3	0.019
BAG1	BCL2-associated athanogene	0.018
IL1A	interleukin 1, alpha	0.018	Human
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.018
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.018
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.018
CFP	complement factor properdin	0.018
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.017
CLEC4D	C-type lectin domain family 4, member D	0.017	Human
APOB	apolipoprotein B (including Ag(x) antigen)	0.017
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.017
ADAM15	ADAM metallopeptidase domain 15	0.017
PTPRE	protein tyrosine phosphatase, receptor type, E	0.017
TRAF6	TNF receptor-associated factor 6	0.017
APOA2	apolipoprotein A-II	0.016
NCOA3	nuclear receptor coactivator 3	0.016
MYOD1	myogenic differentiation 1	0.016
PRKCA	protein kinase C, alpha	0.016
ARRDC3	arrestin domain containing 3	0.016
PDE4DIP	phosphodiesterase 4D interacting protein	0.015
SOD2	superoxide dismutase 2, mitochondrial	0.015
FABP4	fatty acid binding protein 4, adipocyte	0.015
IRF4	interferon regulatory factor 4	0.015
GLIS2	GLIS family zinc finger 2	0.015
CCL14	chemokine (C-C motif) ligand 14	0.015
DSG1	desmoglein 1	0.015
PGRMC1	progesterone receptor membrane component 1	0.015
CXCR2	chemokine (C-X-C motif) receptor 2	0.015
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.015
NCOA1	nuclear receptor coactivator 1	0.014
ZC3H12A	zinc finger CCCH-type containing 12A	0.014
STAT5A	signal transducer and activator of transcription 5A	0.014
CSF3	colony stimulating factor 3 (granulocyte)	0.014
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.014
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.014
TXNDC2	thioredoxin domain containing 2 (spermatozoa)	0.014
EZR	ezrin	0.014
IL7R	interleukin 7 receptor	0.014
IGSF21	immunoglobin superfamily, member 21	0.014
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.014
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.014
IL6	interleukin 6 (interferon, beta 2)	0.013
DSG3	desmoglein 3	0.013
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.013	Human
RIPK2	receptor-interacting serine-threonine kinase 2	0.013
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.013
SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	0.013
TBC1D10A	TBC1 domain family, member 10A	0.013
BCL2A1	BCL2-related protein A1	0.013
F11R	F11 receptor	0.013
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.013
TRAF1	TNF receptor-associated factor 1	0.013
GPR109B	G protein-coupled receptor 109B	0.013
SREBF2	sterol regulatory element binding transcription factor 2	0.013
G6PC	glucose-6-phosphatase, catalytic subunit	0.013
CLEC7A	C-type lectin domain family 7, member A	0.013
FHL1	four and a half LIM domains 1	0.012
ADRB2	adrenergic, beta-2-, receptor, surface	0.012	Human
PPARA	peroxisome proliferator-activated receptor alpha	0.012	Human
LOXL4	lysyl oxidase-like 4	0.012
CD83	CD83 molecule	0.012
PI3	peptidase inhibitor 3, skin-derived	0.012
NCF1	neutrophil cytosolic factor 1	0.012
S100A9	S100 calcium binding protein A9	0.012
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.012
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.012
BCL3	B-cell CLL/lymphoma 3	0.012
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.012
LNX1	ligand of numb-protein X 1	0.011
POU2F2	POU class 2 homeobox 2	0.011
PRDX1	peroxiredoxin 1	0.011
MAP2K1	mitogen-activated protein kinase kinase 1	0.011
ASGR1	asialoglycoprotein receptor 1	0.011
LRRK2	leucine-rich repeat kinase 2	0.011
GPR87	G protein-coupled receptor 87	0.011
SSTR3	somatostatin receptor 3	0.011
TSHR	thyroid stimulating hormone receptor	0.011
GFAP	glial fibrillary acidic protein	0.011
WASF1	WAS protein family, member 1	0.011
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.011
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.011
IVL	involucrin	0.011
EPAS1	endothelial PAS domain protein 1	0.011
HSPA1B	heat shock 70kDa protein 1B	0.011
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.011
TACSTD2	tumor-associated calcium signal transducer 2	0.011
ATP5J	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6	0.011
MED14	mediator complex subunit 14	0.011
FAM83C	family with sequence similarity 83, member C	0.011
SOS1	son of sevenless homolog 1 (Drosophila)	0.011
CCDC115	coiled-coil domain containing 115	0.011
RHCG	Rh family, C glycoprotein	0.011
AGXT	alanine-glyoxylate aminotransferase	0.011
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.011
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.011
NLRP3	NLR family, pyrin domain containing 3	0.011
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.011
CRHBP	corticotropin releasing hormone binding protein	0.010
NCOA2	nuclear receptor coactivator 2	0.010
MXD1	MAX dimerization protein 1	0.010
TPPP	tubulin polymerization promoting protein	0.010
BAG3	BCL2-associated athanogene 3	0.010
GK	glycerol kinase	0.010
APOC2	apolipoprotein C-II	0.010
ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	0.010
CD2	CD2 molecule	0.010
KRT14	keratin 14	0.010
CCL7	chemokine (C-C motif) ligand 7	0.010
SESN2	sestrin 2	0.010
GPR84	G protein-coupled receptor 84	0.010
GSK3B	glycogen synthase kinase 3 beta	0.010
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.010
APOE	apolipoprotein E	0.010
HTR3A	5-hydroxytryptamine (serotonin) receptor 3A	0.010
PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	0.010
CTNNBIP1	catenin, beta interacting protein 1	0.010
IL1F9	interleukin 1 family, member 9	0.010	Human
EGFR	epidermal growth factor receptor	0.010
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.010