IMP

Process View

Homo sapiens

22 genes annotated in human

nf kappab import into nucleus

The directed movement of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nf kappab import into nucleus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "nf kappab import into nucleus" (in gray)

Name	Description	Probability	Func Analog Organism
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.990
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.978
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.884
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.752
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.680
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.635
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.553
IL1R1	interleukin 1 receptor, type I	0.505
IL8	interleukin 8	0.478
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.472	Human
BTRC	beta-transducin repeat containing	0.395	Fly
BCL3	B-cell CLL/lymphoma 3	0.354
MYD88	myeloid differentiation primary response gene (88)	0.347
TNIP2	TNFAIP3 interacting protein 2	0.345
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.335
CCR5	chemokine (C-C motif) receptor 5	0.316
SKP1	S-phase kinase-associated protein 1	0.274
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.269
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.268
FBXW11	F-box and WD repeat domain containing 11	0.252	Mouse Fly
CXCL2	chemokine (C-X-C motif) ligand 2	0.239
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.231
IL1B	interleukin 1, beta	0.227
CUL1	cullin 1	0.206
CCL4	chemokine (C-C motif) ligand 4	0.190	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.183
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.174
TNIP1	TNFAIP3 interacting protein 1	0.152
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.137
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.122	Human Rat
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.114
CCL2	chemokine (C-C motif) ligand 2	0.095	Human
CCR1	chemokine (C-C motif) receptor 1	0.093
CCL5	chemokine (C-C motif) ligand 5	0.091	Human
ICAM1	intercellular adhesion molecule 1	0.089
RNF31	ring finger protein 31	0.083
TNF	tumor necrosis factor	0.081
CFLAR	CASP8 and FADD-like apoptosis regulator	0.079
IRAK2	interleukin-1 receptor-associated kinase 2	0.070
IL6	interleukin 6 (interferon, beta 2)	0.058
IL1R2	interleukin 1 receptor, type II	0.058
CCL8	chemokine (C-C motif) ligand 8	0.058	Human
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.049
RANBP3	RAN binding protein 3	0.047
DPP4	dipeptidyl-peptidase 4	0.043
ZNF84	zinc finger protein 84	0.041
TLR2	toll-like receptor 2	0.040
CCL20	chemokine (C-C motif) ligand 20	0.037	Human
CCL22	chemokine (C-C motif) ligand 22	0.036	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.033
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.033
HIPK3	homeodomain interacting protein kinase 3	0.032
IDE	insulin-degrading enzyme	0.031
BBS10	Bardet-Biedl syndrome 10	0.031
CXCL5	chemokine (C-X-C motif) ligand 5	0.030
TXN	thioredoxin	0.030
YAP1	Yes-associated protein 1	0.029
BCL2A1	BCL2-related protein A1	0.027
PLAUR	plasminogen activator, urokinase receptor	0.024
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.024	Human
FYB	FYN binding protein	0.024
GBP1	guanylate binding protein 1, interferon-inducible	0.023
CXCL10	chemokine (C-X-C motif) ligand 10	0.023
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.023
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.023
CCL13	chemokine (C-C motif) ligand 13	0.023	Human
CCR7	chemokine (C-C motif) receptor 7	0.023
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.023
CHUK	conserved helix-loop-helix ubiquitous kinase	0.023
LY96	lymphocyte antigen 96	0.023
ADAM15	ADAM metallopeptidase domain 15	0.021
SNAI1	snail homolog 1 (Drosophila)	0.021
CCL7	chemokine (C-C motif) ligand 7	0.021	Human
CXCL11	chemokine (C-X-C motif) ligand 11	0.020
CCL3	chemokine (C-C motif) ligand 3	0.020	Human
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.020
CXCL13	chemokine (C-X-C motif) ligand 13	0.019
CCR4	chemokine (C-C motif) receptor 4	0.019
IL2RB	interleukin 2 receptor, beta	0.018
ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	0.018
FBXW2	F-box and WD repeat domain containing 2	0.018
LAT	linker for activation of T cells	0.018
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.018
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.018
ZNF432	zinc finger protein 432	0.017
CD83	CD83 molecule	0.017
ZNF140	zinc finger protein 140	0.017	Human
TLR4	toll-like receptor 4	0.017
ACTN4	actinin, alpha 4	0.017
AQP9	aquaporin 9	0.016
BIRC3	baculoviral IAP repeat containing 3	0.016
IL7R	interleukin 7 receptor	0.016
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.016
IFNG	interferon, gamma	0.016
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.016
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.015
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.015
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.015
SELE	selectin E	0.015
BTK	Bruton agammaglobulinemia tyrosine kinase	0.015
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.014
ZC3H12A	zinc finger CCCH-type containing 12A	0.014
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.014
NOG	noggin	0.014
CCL19	chemokine (C-C motif) ligand 19	0.014
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.014
ZNF304	zinc finger protein 304	0.014
SAMD9L	sterile alpha motif domain containing 9-like	0.014
FPR3	formyl peptide receptor 3	0.013
PLEK	pleckstrin	0.013
RGS1	regulator of G-protein signaling 1	0.013
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.012
CH25H	cholesterol 25-hydroxylase	0.012
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.012
IL10	interleukin 10	0.012
HOXA9	homeobox A9	0.012
NLRC4	NLR family, CARD domain containing 4	0.012
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.012
FBXO33	F-box protein 33	0.012
ZNF529	zinc finger protein 529	0.012
CD2	CD2 molecule	0.012
ZNF189	zinc finger protein 189	0.012
CLPX	ClpX caseinolytic peptidase X homolog (E. coli)	0.012
LASP1	LIM and SH3 protein 1	0.012
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.011
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.011
TREM1	triggering receptor expressed on myeloid cells 1	0.011
ZRANB1	zinc finger, RAN-binding domain containing 1	0.011
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.011
VCL	vinculin	0.011
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.011
TICAM2	toll-like receptor adaptor molecule 2	0.011
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.011
IL18RAP	interleukin 18 receptor accessory protein	0.011
IL1A	interleukin 1, alpha	0.011	Human
ARRB1	arrestin, beta 1	0.011
FBXW7	F-box and WD repeat domain containing 7	0.011
C1orf93	chromosome 1 open reading frame 93	0.010
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.010
PTPRE	protein tyrosine phosphatase, receptor type, E	0.010
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.010
CCL11	chemokine (C-C motif) ligand 11	0.010	Human
UBD	ubiquitin D	0.010
IL21R	interleukin 21 receptor	0.010
NCF1	neutrophil cytosolic factor 1	0.010
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.010
TRIM21	tripartite motif containing 21	0.010
INHBA	inhibin, beta A	0.010
MYH9	myosin, heavy chain 9, non-muscle	0.010