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Homo sapiens

1 genes annotated in human

ventral spinal cord interneuron differentiation

The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ventral spinal cord interneuron differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ventral spinal cord interneuron differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
SUFU	suppressor of fused homolog (Drosophila)	1.000	Mouse
NOTCH3	notch 3	1.000
NOTCH1	notch 1	0.999
GLI1	GLI family zinc finger 1	0.999	Zebrafish
TAL1	T-cell acute lymphocytic leukemia 1	0.990
STK36	serine/threonine kinase 36	0.959
PEX26	peroxisomal biogenesis factor 26	0.952
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.775
QPRT	quinolinate phosphoribosyltransferase	0.728
ZNF764	zinc finger protein 764	0.652
VHL	von Hippel-Lindau tumor suppressor	0.515
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.480
NOTCH2	notch 2	0.455
GFI1B	growth factor independent 1B transcription repressor	0.422
LDB1	LIM domain binding 1	0.372
ZNF263	zinc finger protein 263	0.326
MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))	0.263
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.249
SEC24D	SEC24 family, member D (S. cerevisiae)	0.220
TCF4	transcription factor 4	0.161
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.125
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.114
GLIS3	GLIS family zinc finger 3	0.112
XIAP	X-linked inhibitor of apoptosis	0.108
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.093
LMX1A	LIM homeobox transcription factor 1, alpha	0.078
LBX1	ladybird homeobox 1	0.077
DLL1	delta-like 1 (Drosophila)	0.063	Human
NKX2-2	NK2 homeobox 2	0.059	Zebrafish Mouse
LDB2	LIM domain binding 2	0.059
PDX1	pancreatic and duodenal homeobox 1	0.055
GLI3	GLI family zinc finger 3	0.055	Mouse
SOX1	SRY (sex determining region Y)-box 1	0.049
KRTAP4-12	keratin associated protein 4-12	0.047
TCF21	transcription factor 21	0.047
AMN	amnionless homolog (mouse)	0.046
LHX2	LIM homeobox 2	0.043
BAI1	brain-specific angiogenesis inhibitor 1	0.042
HOXD12	homeobox D12	0.042
RAX	retina and anterior neural fold homeobox	0.042
GBX2	gastrulation brain homeobox 2	0.038
SMAD9	SMAD family member 9	0.038
SOX2	SRY (sex determining region Y)-box 2	0.037
HES5	hairy and enhancer of split 5 (Drosophila)	0.037
NEUROD1	neurogenic differentiation 1	0.036
OLIG2	oligodendrocyte lineage transcription factor 2	0.036	Zebrafish
ISL1	ISL LIM homeobox 1	0.035
TP73	tumor protein p73	0.035
RUNX1	runt-related transcription factor 1	0.033
POU3F1	POU class 3 homeobox 1	0.033
POU3F3	POU class 3 homeobox 3	0.032
POU3F2	POU class 3 homeobox 2	0.031
EFNB2	ephrin-B2	0.031
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.030
DLL4	delta-like 4 (Drosophila)	0.029
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.029
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.028
SIX3	SIX homeobox 3	0.028
FGF3	fibroblast growth factor 3	0.027
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.027
ZFPM1	zinc finger protein, multitype 1	0.027
MAML1	mastermind-like 1 (Drosophila)	0.027
KIF3B	kinesin family member 3B	0.026
SMAD1	SMAD family member 1	0.026
NKX2-1	NK2 homeobox 1	0.026
SOX11	SRY (sex determining region Y)-box 11	0.026
CNTFR	ciliary neurotrophic factor receptor	0.025
EGFL7	EGF-like-domain, multiple 7	0.024
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.024
WNT6	wingless-type MMTV integration site family, member 6	0.024
SFRP5	secreted frizzled-related protein 5	0.024
PRPH	peripherin	0.024
FOXD3	forkhead box D3	0.023
IPO13	importin 13	0.023
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.023
DLL3	delta-like 3 (Drosophila)	0.022	Human
GLI2	GLI family zinc finger 2	0.022	Mouse
C1QL1	complement component 1, q subcomponent-like 1	0.022
FEV	FEV (ETS oncogene family)	0.022
LMO2	LIM domain only 2 (rhombotin-like 1)	0.022
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.022
BHLHE23	basic helix-loop-helix family, member e23	0.021
FOXB1	forkhead box B1	0.021
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.021
PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor	0.021
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.021
LMO1	LIM domain only 1 (rhombotin 1)	0.020
HES2	hairy and enhancer of split 2 (Drosophila)	0.020
NELL2	NEL-like 2 (chicken)	0.020
LHX5	LIM homeobox 5	0.020
BARX1	BARX homeobox 1	0.020
HOXD13	homeobox D13	0.020
PAX2	paired box 2	0.019
HOXD9	homeobox D9	0.019
CDX2	caudal type homeobox 2	0.019
ALX4	ALX homeobox 4	0.019
SOX18	SRY (sex determining region Y)-box 18	0.019
CSPG5	chondroitin sulfate proteoglycan 5 (neuroglycan C)	0.019
ALX3	ALX homeobox 3	0.019
MNX1	motor neuron and pancreas homeobox 1	0.019
WNT10A	wingless-type MMTV integration site family, member 10A	0.019
ECEL1	endothelin converting enzyme-like 1	0.019
HOXB9	homeobox B9	0.019
LHX1	LIM homeobox 1	0.018
ATN1	atrophin 1	0.018
NR2E1	nuclear receptor subfamily 2, group E, member 1	0.018
APC2	adenomatosis polyposis coli 2	0.018
GATA5	GATA binding protein 5	0.018
PAX6	paired box 6	0.018	Mouse
HAND2	heart and neural crest derivatives expressed 2	0.017
OTP	orthopedia homeobox	0.017
SLC16A11	solute carrier family 16, member 11 (monocarboxylic acid transporter 11)	0.017
CALCR	calcitonin receptor	0.017
ITSN1	intersectin 1 (SH3 domain protein)	0.017
TINAGL1	tubulointerstitial nephritis antigen-like 1	0.017
VAX2	ventral anterior homeobox 2	0.017
NOVA2	neuro-oncological ventral antigen 2	0.016
CRHR1	corticotropin releasing hormone receptor 1	0.016
DRD2	dopamine receptor D2	0.016
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.016
WNT4	wingless-type MMTV integration site family, member 4	0.016
PHOX2A	paired-like homeobox 2a	0.016
DLX4	distal-less homeobox 4	0.016
MYT1	myelin transcription factor 1	0.016
KLHL35	kelch-like 35 (Drosophila)	0.016
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.016
HOXB13	homeobox B13	0.016
CHGA	chromogranin A (parathyroid secretory protein 1)	0.016
GPR44	G protein-coupled receptor 44	0.016
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.016
TBX21	T-box 21	0.016
FOXL2	forkhead box L2	0.015
NKX3-2	NK3 homeobox 2	0.015
SALL2	sal-like 2 (Drosophila)	0.015
INSM1	insulinoma-associated 1	0.015
HBQ1	hemoglobin, theta 1	0.015
KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.015
HOXC12	homeobox C12	0.015
MYOD1	myogenic differentiation 1	0.015
LTBP4	latent transforming growth factor beta binding protein 4	0.015
MEGF6	multiple EGF-like-domains 6	0.015
MSX1	msh homeobox 1	0.015
WNT1	wingless-type MMTV integration site family, member 1	0.015
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.015
NEUROG2	neurogenin 2	0.015
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.015
PAX3	paired box 3	0.015
HOXC5	homeobox C5	0.014
JAG2	jagged 2	0.014	Human Zebrafish
EN1	engrailed homeobox 1	0.014
NELL1	NEL-like 1 (chicken)	0.014
ARX	aristaless related homeobox	0.014
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.014
DCX	doublecortin	0.014
GGN	gametogenetin	0.014
GJA3	gap junction protein, alpha 3, 46kDa	0.014
HOXD3	homeobox D3	0.014
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.014
EMX1	empty spiracles homeobox 1	0.014
HOXD11	homeobox D11	0.014
FOXL1	forkhead box L1	0.014
FOXF2	forkhead box F2	0.014
NGB	neuroglobin	0.014
PSPN	persephin	0.013
ZBTB16	zinc finger and BTB domain containing 16	0.013
TBX1	T-box 1	0.013
PYY	peptide YY	0.013
CRTAC1	cartilage acidic protein 1	0.013
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.013
NEUROG3	neurogenin 3	0.013
RUNDC3A	RUN domain containing 3A	0.013
WSCD1	WSC domain containing 1	0.013
PAX7	paired box 7	0.013
TBX5	T-box 5	0.013
JPH3	junctophilin 3	0.013
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.013
HOXC8	homeobox C8	0.013
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.013
PRDM13	PR domain containing 13	0.013
NOTCH4	notch 4	0.013
SFRP1	secreted frizzled-related protein 1	0.013
DUSP9	dual specificity phosphatase 9	0.013
SOX21	SRY (sex determining region Y)-box 21	0.013
BRSK2	BR serine/threonine kinase 2	0.013
POU3F4	POU class 3 homeobox 4	0.013
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.013
NEUROG1	neurogenin 1	0.013
FOXG1	forkhead box G1	0.013
AATK	apoptosis-associated tyrosine kinase	0.013
GATA2	GATA binding protein 2	0.013	Zebrafish Mouse
FOXF1	forkhead box F1	0.013
HNF1A	HNF1 homeobox A	0.013
INHBB	inhibin, beta B	0.013
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.012
NFYC	nuclear transcription factor Y, gamma	0.012
TTC9B	tetratricopeptide repeat domain 9B	0.012
ACTL6B	actin-like 6B	0.012
MEGF11	multiple EGF-like-domains 11	0.012
RBMXL2	RNA binding motif protein, X-linked-like 2	0.012
NKX6-2	NK6 homeobox 2	0.012	Mouse
PNMT	phenylethanolamine N-methyltransferase	0.012
PDZD4	PDZ domain containing 4	0.012
GALR2	galanin receptor 2	0.012
FOXA2	forkhead box A2	0.012
SCUBE1	signal peptide, CUB domain, EGF-like 1	0.012
SAMD11	sterile alpha motif domain containing 11	0.012
MAB21L1	mab-21-like 1 (C. elegans)	0.012
VSX1	visual system homeobox 1	0.012
FGF4	fibroblast growth factor 4	0.012
GHSR	growth hormone secretagogue receptor	0.012
C2CD4C	C2 calcium-dependent domain containing 4C	0.012
DIO3	deiodinase, iodothyronine, type III	0.012
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.012
EPHB3	EPH receptor B3	0.012
SMO	smoothened homolog (Drosophila)	0.012
ISL2	ISL LIM homeobox 2	0.012
USHBP1	Usher syndrome 1C binding protein 1	0.012
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.012
ELFN2	extracellular leucine-rich repeat and fibronectin type III domain containing 2	0.012
HES1	hairy and enhancer of split 1, (Drosophila)	0.012
AGRN	agrin	0.012
PROX1	prospero homeobox 1	0.012
ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)	0.012
ZAN	zonadhesin	0.012
NDP	Norrie disease (pseudoglioma)	0.012
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.012
HOXD1	homeobox D1	0.012
NTSR1	neurotensin receptor 1 (high affinity)	0.012
HOXD4	homeobox D4	0.012
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.012
RPRML	reprimo-like	0.012
BMP7	bone morphogenetic protein 7	0.012
GJD2	gap junction protein, delta 2, 36kDa	0.012
OAF	OAF homolog (Drosophila)	0.012
ACPT	acid phosphatase, testicular	0.011
POU4F3	POU class 4 homeobox 3	0.011
ANKS3	ankyrin repeat and sterile alpha motif domain containing 3	0.011
HOXB8	homeobox B8	0.011
NKPD1	NTPase, KAP family P-loop domain containing 1	0.011
DRD4	dopamine receptor D4	0.011	Zebrafish
LAMA5	laminin, alpha 5	0.011
BCAN	brevican	0.011
HOXA11	homeobox A11	0.011
SHH	sonic hedgehog	0.011	Rat
GSX2	GS homeobox 2	0.011
IGDCC3	immunoglobulin superfamily, DCC subclass, member 3	0.011
ADAM17	ADAM metallopeptidase domain 17	0.011
POU4F1	POU class 4 homeobox 1	0.011
FIBCD1	fibrinogen C domain containing 1	0.011
NPTXR	neuronal pentraxin receptor	0.011
FOXE3	forkhead box E3	0.011
NKX6-1	NK6 homeobox 1	0.011	Mouse
PCSK2	proprotein convertase subtilisin/kexin type 2	0.011
PITPNB	phosphatidylinositol transfer protein, beta	0.011
LPHN1	latrophilin 1	0.011
TLX3	T-cell leukemia homeobox 3	0.011
ZNF675	zinc finger protein 675	0.011
ADAMTSL4	ADAMTS-like 4	0.011
COL2A1	collagen, type II, alpha 1	0.011
GALR1	galanin receptor 1	0.011
SIX2	SIX homeobox 2	0.011
BARHL1	BarH-like homeobox 1	0.011
TTYH1	tweety homolog 1 (Drosophila)	0.011
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.011	Mouse
GATA4	GATA binding protein 4	0.011
GFRA3	GDNF family receptor alpha 3	0.011
DGKI	diacylglycerol kinase, iota	0.011
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.011
CALCA	calcitonin-related polypeptide alpha	0.011
TSEN15	tRNA splicing endonuclease 15 homolog (S. cerevisiae)	0.010
SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.010
NKX2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.010
FAM181B	family with sequence similarity 181, member B	0.010
TLX1	T-cell leukemia homeobox 1	0.010
IHH	Indian hedgehog	0.010
ONECUT2	one cut homeobox 2	0.010
TH	tyrosine hydroxylase	0.010
FZD10	frizzled homolog 10 (Drosophila)	0.010
BMP6	bone morphogenetic protein 6	0.010
GFAP	glial fibrillary acidic protein	0.010
PTCH1	patched 1	0.010
SALL1	sal-like 1 (Drosophila)	0.010
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.010
HES7	hairy and enhancer of split 7 (Drosophila)	0.010
BCL2L10	BCL2-like 10 (apoptosis facilitator)	0.010
NPAS3	neuronal PAS domain protein 3	0.010
SSTR1	somatostatin receptor 1	0.010
GPR161	G protein-coupled receptor 161	0.010
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.010
SLC17A7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.010
SIX6	SIX homeobox 6	0.010
NEURL	neuralized homolog (Drosophila)	0.010
CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.010