IMP
Process View
positive regulation of small gtpase mediated signal transduction
Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of small gtpase mediated signal transduction"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 1.000 | Fly | |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 1.000 | Fly | |
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.999 | Fly | |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.999 | Fly | |
| FGFR2 | fibroblast growth factor receptor 2 | 0.980 | ||
| EGFR | epidermal growth factor receptor | 0.956 | ||
| FGFR1 | fibroblast growth factor receptor 1 | 0.927 | ||
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.907 | Fly | |
| PLCG1 | phospholipase C, gamma 1 | 0.864 | ||
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.838 | Fly | |
| JAG1 | jagged 1 | 0.798 | ||
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.612 | Fly | |
| IGF1R | insulin-like growth factor 1 receptor | 0.587 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.562 | ||
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.459 | Rat Fly | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.424 | ||
| NOTCH1 | notch 1 | 0.398 | Human | |
| FGF10 | fibroblast growth factor 10 | 0.396 | ||
| ZNF496 | zinc finger protein 496 | 0.309 | ||
| SNIP1 | Smad nuclear interacting protein 1 | 0.243 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.177 | Fly | |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.166 | Fly | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.162 | ||
| NOTCH3 | notch 3 | 0.160 | Human | |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.129 | ||
| LAT | linker for activation of T cells | 0.123 | ||
| NGF | nerve growth factor (beta polypeptide) | 0.113 | ||
| HP | haptoglobin | 0.111 | ||
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.098 | ||
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.093 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.086 | ||
| MOBKL3 | MOB1, Mps One Binder kinase activator-like 3 (yeast) | 0.083 | ||
| SLMAP | sarcolemma associated protein | 0.083 | ||
| SRPK2 | SRSF protein kinase 2 | 0.083 | ||
| ITGB1BP3 | integrin beta 1 binding protein 3 | 0.081 | ||
| RHOA | ras homolog gene family, member A | 0.079 | ||
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.076 | Fly | |
| MAPK3 | mitogen-activated protein kinase 3 | 0.075 | Fly | |
| MAPK14 | mitogen-activated protein kinase 14 | 0.074 | ||
| PTCHD2 | patched domain containing 2 | 0.073 | ||
| STRN | striatin, calmodulin binding protein | 0.059 | ||
| A2M | alpha-2-macroglobulin | 0.058 | ||
| TNK2 | tyrosine kinase, non-receptor, 2 | 0.057 | ||
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.057 | ||
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.052 | Fly | |
| ABI1 | abl-interactor 1 | 0.046 | ||
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.044 | ||
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.042 | ||
| NCK1 | NCK adaptor protein 1 | 0.042 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.040 | ||
| BAG1 | BCL2-associated athanogene | 0.040 | ||
| ARRB2 | arrestin, beta 2 | 0.038 | Human | |
| RHEB | Ras homolog enriched in brain | 0.037 | ||
| PEBP4 | phosphatidylethanolamine-binding protein 4 | 0.036 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.036 | ||
| ARRB1 | arrestin, beta 1 | 0.032 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.032 | ||
| APC | adenomatous polyposis coli | 0.031 | ||
| NAV1 | neuron navigator 1 | 0.031 | ||
| FGF7 | fibroblast growth factor 7 | 0.030 | Human | |
| MPRIP | myosin phosphatase Rho interacting protein | 0.028 | ||
| MAP2K2 | mitogen-activated protein kinase kinase 2 | 0.028 | Fly | |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.026 | Rat | |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.024 | ||
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.024 | ||
| GRB10 | growth factor receptor-bound protein 10 | 0.022 | ||
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.022 | ||
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.022 | ||
| LCAT | lecithin-cholesterol acyltransferase | 0.021 | ||
| STK4 | serine/threonine kinase 4 | 0.021 | ||
| FGFR1OP2 | FGFR1 oncogene partner 2 | 0.021 | ||
| DLL1 | delta-like 1 (Drosophila) | 0.021 | ||
| APOC1 | apolipoprotein C-I | 0.021 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.020 | ||
| STMN2 | stathmin-like 2 | 0.020 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.020 | ||
| JAG2 | jagged 2 | 0.019 | ||
| INSR | insulin receptor | 0.019 | ||
| FGF1 | fibroblast growth factor 1 (acidic) | 0.018 | Human | |
| SIKE1 | suppressor of IKBKE 1 | 0.018 | ||
| DIAPH1 | diaphanous homolog 1 (Drosophila) | 0.018 | ||
| MAPK10 | mitogen-activated protein kinase 10 | 0.018 | ||
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.018 | ||
| NTF4 | neurotrophin 4 | 0.018 | ||
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.018 | ||
| PRPF38A | PRP38 pre-mRNA processing factor 38 (yeast) domain containing A | 0.017 | ||
| STK3 | serine/threonine kinase 3 | 0.017 | ||
| GAB2 | GRB2-associated binding protein 2 | 0.017 | ||
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.017 | ||
| EPOR | erythropoietin receptor | 0.017 | ||
| DCN | decorin | 0.017 | ||
| SFN | stratifin | 0.016 | Fly | |
| TF | transferrin | 0.016 | ||
| COL1A2 | collagen, type I, alpha 2 | 0.016 | ||
| USPL1 | ubiquitin specific peptidase like 1 | 0.016 | ||
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.015 | ||
| AXL | AXL receptor tyrosine kinase | 0.015 | ||
| STK24 | serine/threonine kinase 24 | 0.015 | ||
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.015 | Fly | |
| PBK | PDZ binding kinase | 0.015 | ||
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.015 | ||
| APOC3 | apolipoprotein C-III | 0.015 | ||
| RBM8A | RNA binding motif protein 8A | 0.014 | ||
| DLG1 | discs, large homolog 1 (Drosophila) | 0.014 | ||
| ARHGAP1 | Rho GTPase activating protein 1 | 0.014 | ||
| KSR1 | kinase suppressor of ras 1 | 0.013 | Fly | |
| RAP1A | RAP1A, member of RAS oncogene family | 0.013 | ||
| PLXNB1 | plexin B1 | 0.013 | ||
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.013 | ||
| BTRC | beta-transducin repeat containing | 0.013 | ||
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.013 | ||
| WDYHV1 | WDYHV motif containing 1 | 0.013 | ||
| JAK2 | Janus kinase 2 | 0.013 | ||
| FBLN1 | fibulin 1 | 0.013 | ||
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.013 | ||
| TSC2 | tuberous sclerosis 2 | 0.012 | ||
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.012 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.011 | ||
| APOA2 | apolipoprotein A-II | 0.011 | ||
| GFI1B | growth factor independent 1B transcription repressor | 0.011 | ||
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.011 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.011 | ||
| ERBB2IP | erbb2 interacting protein | 0.011 | ||
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.011 | ||
| ALB | albumin | 0.011 | ||
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.010 | ||
| RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.010 | ||
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.010 | ||
| LOX | lysyl oxidase | 0.010 |