IMP

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Mus musculus

2 genes annotated in mouse

negative regulation of fibroblast growth factor production

Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of fibroblast growth factor production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of fibroblast growth factor production" (in gray)

Name	Description	Probability	Func Analog Organism
Pax2	paired box gene 2	0.944
Fgf8	fibroblast growth factor 8	0.697
T	brachyury	0.370
Gdnf	glial cell line derived neurotrophic factor	0.360
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.343
Lhx1	LIM homeobox protein 1	0.238
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.236
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.215
Amhr2	anti-Mullerian hormone type 2 receptor	0.199
Pax8	paired box gene 8	0.196
Wnt6	wingless-related MMTV integration site 6	0.186	Mouse
Wnt10b	wingless related MMTV integration site 10b	0.135	Mouse
Wnt3a	wingless-related MMTV integration site 3A	0.132	Mouse
Pou3f3	POU domain, class 3, transcription factor 3	0.131
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.129
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.112
Fgf18	fibroblast growth factor 18	0.099
Otx1	orthodenticle homolog 1 (Drosophila)	0.092
Bmp7	bone morphogenetic protein 7	0.090
Kl	klotho	0.089
Col13a1	collagen, type XIII, alpha 1	0.083
Vax1	ventral anterior homeobox containing gene 1	0.083
Shh	sonic hedgehog	0.082
Clic3	chloride intracellular channel 3	0.081
Cdx1	caudal type homeobox 1	0.077
Lmx1a	LIM homeobox transcription factor 1 alpha	0.068
Efna4	ephrin A4	0.067
Lmx1b	LIM homeobox transcription factor 1 beta	0.066
Ephb2	Eph receptor B2	0.066
Fzd10	frizzled homolog 10 (Drosophila)	0.066
Wnt4	wingless-related MMTV integration site 4	0.059	Mouse
Fzd8	frizzled homolog 8 (Drosophila)	0.058
Twist2	twist homolog 2 (Drosophila)	0.057
Npas1	neuronal PAS domain protein 1	0.056
Muc5ac	mucin 5, subtypes A and C, tracheobronchial/gastric	0.055
Rarg	retinoic acid receptor, gamma	0.052
Trp73	transformation related protein 73	0.051
Angpt4	angiopoietin 4	0.051
Hoxa13	homeobox A13	0.050
Rspo1	R-spondin homolog (Xenopus laevis)	0.048
BC018465	cDNA sequence BC018465	0.047
Emid2	EMI domain containing 2	0.047
Pou3f1	POU domain, class 3, transcription factor 1	0.046
Fgfr4	fibroblast growth factor receptor 4	0.046
Krt13	keratin 13	0.046
Neurog1	neurogenin 1	0.045
Tead3	TEA domain family member 3	0.045
Tnni2	troponin I, skeletal, fast 2	0.044
Gli3	GLI-Kruppel family member GLI3	0.044
Slurp1	secreted Ly6/Plaur domain containing 1	0.044
Nog	noggin	0.042
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.042
Porcn	porcupine homolog (Drosophila)	0.041
Emx2	empty spiracles homolog 2 (Drosophila)	0.041
Tctex1d4	Tctex1 domain containing 4	0.041
Emx1	empty spiracles homolog 1 (Drosophila)	0.040
Gli2	GLI-Kruppel family member GLI2	0.040
Ttc16	tetratricopeptide repeat domain 16	0.040
Fgf5	fibroblast growth factor 5	0.039
Crlf1	cytokine receptor-like factor 1	0.039
Hoxa4	homeobox A4	0.038
Otx2	orthodenticle homolog 2 (Drosophila)	0.038
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.038
Krt15	keratin 15	0.038
Lyzl4	lysozyme-like 4	0.038
Btbd17	BTB (POZ) domain containing 17	0.038
Asb10	ankyrin repeat and SOCS box-containing 10	0.036
Scube1	signal peptide, CUB domain, EGF-like 1	0.036
Barx1	BarH-like homeobox 1	0.035
Hoxd11	homeobox D11	0.034
Msx1	homeobox, msh-like 1	0.034
BC024139	cDNA sequence BC024139	0.034
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.032
Uncx	UNC homeobox	0.032
Ribc2	RIB43A domain with coiled-coils 2	0.032
Acan	aggrecan	0.031
Foxn4	forkhead box N4	0.031
Vstm2b	V-set and transmembrane domain containing 2B	0.031
Pitx3	paired-like homeodomain transcription factor 3	0.030
Bik	BCL2-interacting killer	0.030
Hmx1	H6 homeobox 1	0.030
Nkx6-1	NK6 homeobox 1	0.030
Hoxc9	homeobox C9	0.030
Pitx1	paired-like homeodomain transcription factor 1	0.030
Wnt11	wingless-related MMTV integration site 11	0.029
Sim2	single-minded homolog 2 (Drosophila)	0.029
Foxb1	forkhead box B1	0.029
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.029
Gli1	GLI-Kruppel family member GLI1	0.028
Foxd2	forkhead box D2	0.028
Padi3	peptidyl arginine deiminase, type III	0.028
Fgf15	fibroblast growth factor 15	0.028
Barx2	BarH-like homeobox 2	0.028
Wnt9a	wingless-type MMTV integration site 9A	0.028	Mouse
Pou3f2	POU domain, class 3, transcription factor 2	0.027
En1	engrailed 1	0.027
Sox1	SRY-box containing gene 1	0.027
Cldn3	claudin 3	0.027
Foxc2	forkhead box C2	0.027
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.027
Fxyd1	FXYD domain-containing ion transport regulator 1	0.026
Irx4	Iroquois related homeobox 4 (Drosophila)	0.026
Ptk7	PTK7 protein tyrosine kinase 7	0.025
Wnt2b	wingless related MMTV integration site 2b	0.025	Mouse
Fgf3	fibroblast growth factor 3	0.025
Icam5	intercellular adhesion molecule 5, telencephalin	0.025
2610109H07Rik	RIKEN cDNA 2610109H07 gene	0.025
Zbtb7c	zinc finger and BTB domain containing 7C	0.025
Wnt7a	wingless-related MMTV integration site 7A	0.025	Mouse
Rara	retinoic acid receptor, alpha	0.025
Ntn3	netrin 3	0.024
Epha1	Eph receptor A1	0.024
Col2a1	collagen, type II, alpha 1	0.024
Tbx1	T-box 1	0.024
Kcnk3	potassium channel, subfamily K, member 3	0.023
Rsph6a	radial spoke head 6 homolog A (Chlamydomonas)	0.023
Ihh	Indian hedgehog	0.023
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.023
Hmx3	H6 homeobox 3	0.023
Lhx5	LIM homeobox protein 5	0.023
Nrtn	neurturin	0.023
Hoxa2	homeobox A2	0.022
Tcfap2c	transcription factor AP-2, gamma	0.022
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.022
Myl3	myosin, light polypeptide 3	0.022
P2rx6	purinergic receptor P2X, ligand-gated ion channel, 6	0.022
Foxf1a	forkhead box F1a	0.022
Emp2	epithelial membrane protein 2	0.022
Atp2c2	ATPase, Ca++ transporting, type 2C, member 2	0.022
Sult5a1	sulfotransferase family 5A, member 1	0.021
Gpc3	glypican 3	0.021
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.021
Foxl2	forkhead box L2	0.021
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.021
Gipc3	GIPC PDZ domain containing family, member 3	0.021
Lef1	lymphoid enhancer binding factor 1	0.021
Zfp771	zinc finger protein 771	0.021
Eln	elastin	0.020
Mfsd6l	major facilitator superfamily domain containing 6-like	0.020
Tbx2	T-box 2	0.020
Dmbx1	diencephalon/mesencephalon homeobox 1	0.020
Hoxd13	homeobox D13	0.020
Zfp503	zinc finger protein 503	0.020
Pax1	paired box gene 1	0.020
BC021891	cDNA sequence BC021891	0.019
Amh	anti-Mullerian hormone	0.019
Irx1	Iroquois related homeobox 1 (Drosophila)	0.019
Fzd1	frizzled homolog 1 (Drosophila)	0.019
Col22a1	collagen, type XXII, alpha 1	0.019
Prrx2	paired related homeobox 2	0.019
Wnt10a	wingless related MMTV integration site 10a	0.019
Sh3pxd2a	SH3 and PX domains 2A	0.019
Adra2a	adrenergic receptor, alpha 2a	0.019
Adra2b	adrenergic receptor, alpha 2b	0.019
Foxf2	forkhead box F2	0.019
Scn5a	sodium channel, voltage-gated, type V, alpha	0.019
Msln	mesothelin	0.019
Des	desmin	0.019
Pcdh12	protocadherin 12	0.018
Ret	ret proto-oncogene	0.018
Tgfa	transforming growth factor alpha	0.018
Foxi1	forkhead box I1	0.018
Adra2c	adrenergic receptor, alpha 2c	0.018
Hoxa11	homeobox A11	0.018
Bhlhe23	basic helix-loop-helix family, member e23	0.018
Prm3	protamine 3	0.017
Artn	artemin	0.017
Dmrt3	doublesex and mab-3 related transcription factor 3	0.017
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.017
Foxe3	forkhead box E3	0.017
Alx4	aristaless-like homeobox 4	0.017
Fgf17	fibroblast growth factor 17	0.017
Slc27a3	solute carrier family 27 (fatty acid transporter), member 3	0.017
Fgf2	fibroblast growth factor 2	0.017
Nkain4	Na+/K+ transporting ATPase interacting 4	0.017
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.017
Pvrl1	poliovirus receptor-related 1	0.016
Figla	folliculogenesis specific basic helix-loop-helix	0.016
Efna2	ephrin A2	0.016
1700080E11Rik	RIKEN cDNA 1700080E11 gene	0.016
Rem1	rad and gem related GTP binding protein 1	0.016
Nobox	NOBOX oogenesis homeobox	0.016
Hs3st6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.016
Fjx1	four jointed box 1 (Drosophila)	0.016
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.016
Atoh8	atonal homolog 8 (Drosophila)	0.016
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.016
Zfp703	zinc finger protein 703	0.015
Papln	papilin, proteoglycan-like sulfated glycoprotein	0.015
Ank1	ankyrin 1, erythroid	0.015
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.015
Crabp2	cellular retinoic acid binding protein II	0.015
Sox7	SRY-box containing gene 7	0.015
Rasl10a	RAS-like, family 10, member A	0.015
Wnt5b	wingless-related MMTV integration site 5B	0.015	Mouse
Hoxd9	homeobox D9	0.015
Wfdc2	WAP four-disulfide core domain 2	0.015
Ccna1	cyclin A1	0.015
Pax7	paired box gene 7	0.015
Adrb1	adrenergic receptor, beta 1	0.015
Matn4	matrilin 4	0.015
Irs4	insulin receptor substrate 4	0.015
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.015
Hoxb6	homeobox B6	0.014
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.014
Socs1	suppressor of cytokine signaling 1	0.014
Chrdl2	chordin-like 2	0.014
Rarb	retinoic acid receptor, beta	0.014
Gpr3	G-protein coupled receptor 3	0.014
Nfe2l3	nuclear factor, erythroid derived 2, like 3	0.014
Bnc1	basonuclin 1	0.014
Krtdap	keratinocyte differentiation associated protein	0.014
Lrrc56	leucine rich repeat containing 56	0.014
Srcin1	SRC kinase signaling inhibitor 1	0.014
Muc5b	mucin 5, subtype B, tracheobronchial	0.014
Inhbb	inhibin beta-B	0.014
Fgf21	fibroblast growth factor 21	0.014
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.014
Ppl	periplakin	0.014
Plekha4	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	0.014
Cdx2	caudal type homeobox 2	0.014
Fxyd2	FXYD domain-containing ion transport regulator 2	0.014
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.014
Trim62	tripartite motif-containing 62	0.014
Pax3	paired box gene 3	0.013
Adra1b	adrenergic receptor, alpha 1b	0.013
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.013
Alx3	aristaless-like homeobox 3	0.013
Lrp6	low density lipoprotein receptor-related protein 6	0.013
Cpz	carboxypeptidase Z	0.013
Smo	smoothened homolog (Drosophila)	0.013
Wnt2	wingless-related MMTV integration site 2	0.013	Mouse
Alox12b	arachidonate 12-lipoxygenase, 12R type	0.013
Sox9	SRY-box containing gene 9	0.013
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.013
Crybb2	crystallin, beta B2	0.013
Lama5	laminin, alpha 5	0.013
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.013
Msx2	homeobox, msh-like 2	0.013
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.013
Trp63	transformation related protein 63	0.013
Arx	aristaless related homeobox	0.013
Gas1	growth arrest specific 1	0.013
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.013
Sema6c	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C	0.013
Ano1	anoctamin 1, calcium activated chloride channel	0.013
Gpr27	G protein-coupled receptor 27	0.012
Zfp185	zinc finger protein 185	0.012
Il11	interleukin 11	0.012
Ntsr1	neurotensin receptor 1	0.012
Hs6st3	heparan sulfate 6-O-sulfotransferase 3	0.012
Arsi	arylsulfatase i	0.012
Tssk3	testis-specific serine kinase 3	0.012
Sox3	SRY-box containing gene 3	0.012
Sp5	trans-acting transcription factor 5	0.012
Jag2	jagged 2	0.012
Dlx4	distal-less homeobox 4	0.012
Lhb	luteinizing hormone beta	0.012
Onecut1	one cut domain, family member 1	0.012
Tekt2	tektin 2	0.012
Ubxn10	UBX domain protein 10	0.012
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.012
Mgat3	mannoside acetylglucosaminyltransferase 3	0.012
Pnoc	prepronociceptin	0.012
Shank1	SH3/ankyrin domain gene 1	0.012
Lgals7	lectin, galactose binding, soluble 7	0.012
Rab25	RAB25, member RAS oncogene family	0.012
Sox14	SRY-box containing gene 14	0.012
Mybph	myosin binding protein H	0.012
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.012
Prdm6	PR domain containing 6	0.012
Hoxa7	homeobox A7	0.011
Irx2	Iroquois related homeobox 2 (Drosophila)	0.011
Barhl1	BarH-like 1 (Drosophila)	0.011
Olfr70	olfactory receptor 70	0.011
Cdh16	cadherin 16	0.011
Gm4980	predicted gene 4980	0.011
Mmp15	matrix metallopeptidase 15	0.011
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.011
Tnnt3	troponin T3, skeletal, fast	0.011
Gja3	gap junction protein, alpha 3	0.011
Tlx1	T-cell leukemia, homeobox 1	0.011
Oxtr	oxytocin receptor	0.011
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.011
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.011
Foxd3	forkhead box D3	0.011
Sdk1	sidekick homolog 1 (chicken)	0.011
Pyy	peptide YY	0.011
Fign	fidgetin	0.011
Grik3	glutamate receptor, ionotropic, kainate 3	0.011
Azgp1	alpha-2-glycoprotein 1, zinc	0.011
Grid1	glutamate receptor, ionotropic, delta 1	0.011
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.011
Duoxa1	dual oxidase maturation factor 1	0.011
Tmem132e	transmembrane protein 132E	0.011
4931408A02Rik	RIKEN cDNA 4931408A02 gene	0.011
Cbln3	cerebellin 3 precursor protein	0.011
Mog	myelin oligodendrocyte glycoprotein	0.011
Myl7	myosin, light polypeptide 7, regulatory	0.011
Tpte	transmembrane phosphatase with tensin homology	0.011
Fzd2	frizzled homolog 2 (Drosophila)	0.011
Usp43	ubiquitin specific peptidase 43	0.011
Foxq1	forkhead box Q1	0.011
Nkx2-1	NK2 homeobox 1	0.011
Slc5a5	solute carrier family 5 (sodium iodide symporter), member 5	0.011
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.011
Hoxc5	homeobox C5	0.011
Cib2	calcium and integrin binding family member 2	0.011
Fzd7	frizzled homolog 7 (Drosophila)	0.011
Hspb2	heat shock protein 2	0.010
Capn8	calpain 8	0.010
Dnahc1	dynein, axonemal, heavy chain 1	0.010
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.010
Gal3st1	galactose-3-O-sulfotransferase 1	0.010
H1foo	H1 histone family, member O, oocyte-specific	0.010
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.010
Plxna1	plexin A1	0.010
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.010
Tbx15	T-box 15	0.010
U46068	cDNA sequence U46068	0.010
Sfrp1	secreted frizzled-related protein 1	0.010
Slc38a8	solute carrier family 38, member 8	0.010
Dlx5	distal-less homeobox 5	0.010