IMP

Process View

Mus musculus

12 genes annotated in mouse

Multi-species View

tyrosine phosphorylation of stat3 protein

GO:0042503

The process of introducing a phosphate group to a tyrosine residue of a Stat3 protein.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "tyrosine phosphorylation of stat3 protein"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "tyrosine phosphorylation of stat3 protein" (in gray)

Name	Description	Probability	Func Analog Organism
Lepr	leptin receptor	0.997
Otx2	orthodenticle homolog 2 (Drosophila)	0.985
Il6st	interleukin 6 signal transducer	0.967	Human
Stat3	signal transducer and activator of transcription 3	0.944
Emx2	empty spiracles homolog 2 (Drosophila)	0.931
Tgfb1	transforming growth factor, beta 1	0.774
Csf1	colony stimulating factor 1 (macrophage)	0.670
Nos2	nitric oxide synthase 2, inducible	0.644
Il10	interleukin 10	0.599	Mouse
Kdr	kinase insert domain protein receptor	0.562	Mouse
Emx1	empty spiracles homolog 1 (Drosophila)	0.547
Vegfa	vascular endothelial growth factor A	0.533
Tnf	tumor necrosis factor	0.472
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.458
Shh	sonic hedgehog	0.447
Jak2	Janus kinase 2	0.444
Sox2	SRY-box containing gene 2	0.441
Apc	adenomatosis polyposis coli	0.362
Lhx1	LIM homeobox protein 1	0.330	Mouse
Pax2	paired box gene 2	0.320
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.307
Hes5	hairy and enhancer of split 5 (Drosophila)	0.277
Pax6	paired box gene 6	0.274
Esr1	estrogen receptor 1 (alpha)	0.273
Socs3	suppressor of cytokine signaling 3	0.225	Mouse
Stat5a	signal transducer and activator of transcription 5A	0.217
Nodal	nodal	0.209
Smad3	MAD homolog 3 (Drosophila)	0.200
Hes3	hairy and enhancer of split 3 (Drosophila)	0.192	Mouse
Nos3	nitric oxide synthase 3, endothelial cell	0.190
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.181
Phospho1	phosphatase, orphan 1	0.178
Col1a1	collagen, type I, alpha 1	0.145
Otx1	orthodenticle homolog 1 (Drosophila)	0.143
Ctnnb1	catenin (cadherin associated protein), beta 1	0.141
Socs1	suppressor of cytokine signaling 1	0.131
Il6	interleukin 6	0.126	Human
Rag1	recombination activating gene 1	0.120
Il1r1	interleukin 1 receptor, type I	0.117
Ptgs2	prostaglandin-endoperoxide synthase 2	0.109
Lyz2	lysozyme 2	0.107
Pitx2	paired-like homeodomain transcription factor 2	0.100
Lhx3	LIM homeobox protein 3	0.087	Mouse
Ldlr	low density lipoprotein receptor	0.079
Flt4	FMS-like tyrosine kinase 4	0.077	Mouse
Kit	kit oncogene	0.072	Human Mouse
Stat5b	signal transducer and activator of transcription 5B	0.070
Nog	noggin	0.068
Kitl	kit ligand	0.064
Gli3	GLI-Kruppel family member GLI3	0.060
Fgf8	fibroblast growth factor 8	0.057
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.057
Inpp5d	inositol polyphosphate-5-phosphatase D	0.054
Ptch1	patched homolog 1	0.051
Cdh5	cadherin 5	0.051
Cd44	CD44 antigen	0.049
Plcg1	phospholipase C, gamma 1	0.047
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.047
Kiss1	KiSS-1 metastasis-suppressor	0.047
Foxp3	forkhead box P3	0.043
Foxg1	forkhead box G1	0.042
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.042
Hes1	hairy and enhancer of split 1 (Drosophila)	0.041
Jak1	Janus kinase 1	0.041	Mouse
Wt1	Wilms tumor 1 homolog	0.041
Lhx4	LIM homeobox protein 4	0.038	Mouse
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.037
Prop1	paired like homeodomain factor 1	0.037
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.036
Prf1	perforin 1 (pore forming protein)	0.036
Acvr1	activin A receptor, type 1	0.036
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.035
Ccl2	chemokine (C-C motif) ligand 2	0.034
Ptpn2	protein tyrosine phosphatase, non-receptor type 2	0.031	Human
Pou4f2	POU domain, class 4, transcription factor 2	0.031
Insm1	insulinoma-associated 1	0.030
En2	engrailed 2	0.029
Socs2	suppressor of cytokine signaling 2	0.029	Mouse
Gdnf	glial cell line derived neurotrophic factor	0.029
Cish	cytokine inducible SH2-containing protein	0.028	Mouse
Vegfc	vascular endothelial growth factor C	0.028
Tsc2	tuberous sclerosis 2	0.027
Gbx2	gastrulation brain homeobox 2	0.027
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.027
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.027
Foxc2	forkhead box C2	0.026
Nlrp3	NLR family, pyrin domain containing 3	0.026
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.026
Foxc1	forkhead box C1	0.026
Pax3	paired box gene 3	0.025
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.024
Ptprb	protein tyrosine phosphatase, receptor type, B	0.024
Sh2b1	SH2B adaptor protein 1	0.024
Ldb2	LIM domain binding 2	0.023
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.023
Ren1	renin 1 structural	0.023
Cyld	cylindromatosis (turban tumor syndrome)	0.023
Cbl	Casitas B-lineage lymphoma	0.022
Neurog2	neurogenin 2	0.021
Meox2	mesenchyme homeobox 2	0.021
Hesx1	homeobox gene expressed in ES cells	0.021
Msx3	homeobox, msh-like 3	0.020
Tgfbr2	transforming growth factor, beta receptor II	0.020
Flt1	FMS-like tyrosine kinase 1	0.020	Mouse
Drd3	dopamine receptor D3	0.019
Hand1	heart and neural crest derivatives expressed transcript 1	0.019
Wnt1	wingless-related MMTV integration site 1	0.019
She	src homology 2 domain-containing transforming protein E	0.018
Gsc	goosecoid homeobox	0.018
Lhx9	LIM homeobox protein 9	0.018	Mouse
Nf1	neurofibromatosis 1	0.018
Drd2	dopamine receptor D2	0.018
Pdx1	pancreatic and duodenal homeobox 1	0.018
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.017
En1	engrailed 1	0.017
AI118078	expressed sequence AI118078	0.017
Tcra	T-cell receptor alpha chain	0.017
Ret	ret proto-oncogene	0.016
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.016
Fas	Fas (TNF receptor superfamily member 6)	0.016
Atoh7	atonal homolog 7 (Drosophila)	0.016
Neurod1	neurogenic differentiation 1	0.016
Mdfi	MyoD family inhibitor	0.016
Nos1	nitric oxide synthase 1, neuronal	0.016
a	nonagouti	0.016
Spp1	secreted phosphoprotein 1	0.016
Ifna12	interferon alpha 12	0.016	Human
Kiss1r	KISS1 receptor	0.016
Tek	endothelial-specific receptor tyrosine kinase	0.015
Mefv	Mediterranean fever	0.015
Sox9	SRY-box containing gene 9	0.015
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.015
Sox11	SRY-box containing gene 11	0.014
Foxn1	forkhead box N1	0.014
Pax8	paired box gene 8	0.014
Sox17	SRY-box containing gene 17	0.014
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.014
Gm12597	predicted gene 12597	0.014	Human
Galr3	galanin receptor 3	0.014
Rint1	RAD50 interactor 1	0.013
Csf3	colony stimulating factor 3 (granulocyte)	0.013
Prl	prolactin	0.013
Tsc1	tuberous sclerosis 1	0.013
Crygd	crystallin, gamma D	0.013
Cul5	cullin 5	0.013
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.012
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.012
Ifng	interferon gamma	0.012
Vgf	VGF nerve growth factor inducible	0.012
Tmem204	transmembrane protein 204	0.011
Bdkrb2	bradykinin receptor, beta 2	0.011
Igf1	insulin-like growth factor 1	0.011
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.011
Ptf1a	pancreas specific transcription factor, 1a	0.011
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.011
Apaf1	apoptotic peptidase activating factor 1	0.011
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.011
Ifna9	interferon alpha 9	0.011	Human
Rarg	retinoic acid receptor, gamma	0.010
Zeb1	zinc finger E-box binding homeobox 1	0.010
Eya1	eyes absent 1 homolog (Drosophila)	0.010
Foxh1	forkhead box H1	0.010
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.010
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.010