IMP
Process View
Mus musculus
0 genes annotated in mouse
dysostosis
DOID:1934
A bone development disease that results in defective ossification of located in bone.
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In addition to gene-name show these genes:
Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Gli3 | GLI-Kruppel family member GLI3 | 1.000 | Human | |
| Shh | sonic hedgehog | 0.998 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.930 | Human | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.919 | Human | |
| Sox9 | SRY-box containing gene 9 | 0.894 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.866 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.780 | ||
| Foxc2 | forkhead box C2 | 0.747 | ||
| Hoxd13 | homeobox D13 | 0.563 | Human | |
| Pax1 | paired box gene 1 | 0.542 | ||
| Trp63 | transformation related protein 63 | 0.485 | ||
| Runx2 | runt related transcription factor 2 | 0.469 | ||
| Meox2 | mesenchyme homeobox 2 | 0.443 | ||
| Col2a1 | collagen, type II, alpha 1 | 0.388 | ||
| Smo | smoothened homolog (Drosophila) | 0.386 | ||
| Pkd1 | polycystic kidney disease 1 homolog | 0.382 | ||
| Prrx1 | paired related homeobox 1 | 0.349 | ||
| Foxc1 | forkhead box C1 | 0.344 | ||
| Gdf5 | growth differentiation factor 5 | 0.343 | Human | |
| Bmp4 | bone morphogenetic protein 4 | 0.317 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.267 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.251 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.245 | ||
| Ptch1 | patched homolog 1 | 0.237 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.207 | ||
| Hoxa13 | homeobox A13 | 0.184 | ||
| Hoxd11 | homeobox D11 | 0.176 | ||
| Sox11 | SRY-box containing gene 11 | 0.168 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.149 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.138 | ||
| Fgf9 | fibroblast growth factor 9 | 0.116 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.109 | ||
| Alx4 | aristaless-like homeobox 4 | 0.106 | ||
| Lfng | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.091 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.090 | ||
| Twist2 | twist homolog 2 (Drosophila) | 0.089 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.079 | ||
| Gli1 | GLI-Kruppel family member GLI1 | 0.079 | ||
| Bmpr1b | bone morphogenetic protein receptor, type 1B | 0.077 | Human | |
| Alx1 | ALX homeobox 1 | 0.065 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.063 | ||
| Hoxa11 | homeobox A11 | 0.062 | ||
| Dll3 | delta-like 3 (Drosophila) | 0.056 | Human | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.054 | ||
| Tcf7l1 | transcription factor 7-like 1 (T-cell specific, HMG box) | 0.052 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.052 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.051 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.045 | ||
| Gtf2ird1 | general transcription factor II I repeat domain-containing 1 | 0.044 | ||
| Cyp26a1 | cytochrome P450, family 26, subfamily a, polypeptide 1 | 0.041 | ||
| Msx2 | homeobox, msh-like 2 | 0.040 | Human | |
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.038 | ||
| Pax3 | paired box gene 3 | 0.038 | ||
| Npr2 | natriuretic peptide receptor 2 | 0.037 | ||
| Egfr | epidermal growth factor receptor | 0.037 | ||
| Tbx15 | T-box 15 | 0.035 | ||
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.035 | ||
| Ror1 | receptor tyrosine kinase-like orphan receptor 1 | 0.035 | ||
| Chrd | chordin | 0.034 | ||
| Lmna | lamin A | 0.033 | ||
| Msx1 | homeobox, msh-like 1 | 0.033 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.033 | ||
| En1 | engrailed 1 | 0.032 | ||
| Prrx2 | paired related homeobox 2 | 0.030 | ||
| Fgf10 | fibroblast growth factor 10 | 0.030 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.029 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.029 | ||
| Sall4 | sal-like 4 (Drosophila) | 0.029 | ||
| Ltbp1 | latent transforming growth factor beta binding protein 1 | 0.028 | ||
| Hesx1 | homeobox gene expressed in ES cells | 0.027 | ||
| T | brachyury | 0.027 | ||
| En2 | engrailed 2 | 0.027 | ||
| Gja1 | gap junction protein, alpha 1 | 0.026 | Human | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.026 | ||
| Acvr1 | activin A receptor, type 1 | 0.025 | ||
| Fmn1 | formin 1 | 0.025 | ||
| Sfn | stratifin | 0.024 | ||
| Nkx2-1 | NK2 homeobox 1 | 0.024 | ||
| Rpl38 | ribosomal protein L38 | 0.024 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.024 | ||
| Sfrp2 | secreted frizzled-related protein 2 | 0.023 | ||
| Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.023 | ||
| Zic2 | zinc finger protein of the cerebellum 2 | 0.023 | ||
| Pkdcc | protein kinase domain containing, cytoplasmic | 0.023 | ||
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.022 | ||
| Pthlh | parathyroid hormone-like peptide | 0.021 | ||
| Apc | adenomatosis polyposis coli | 0.021 | ||
| Hoxa10 | homeobox A10 | 0.020 | ||
| Tbx3 | T-box 3 | 0.020 | ||
| Thra | thyroid hormone receptor alpha | 0.020 | ||
| Hbb-bh1 | hemoglobin Z, beta-like embryonic chain | 0.020 | ||
| Bmp2 | bone morphogenetic protein 2 | 0.020 | Human | |
| Rhob | ras homolog gene family, member B | 0.020 | ||
| Zbtb16 | zinc finger and BTB domain containing 16 | 0.019 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.019 | ||
| Ihh | Indian hedgehog | 0.019 | ||
| Emid2 | EMI domain containing 2 | 0.018 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.017 | ||
| Efnb2 | ephrin B2 | 0.017 | ||
| Hba-x | hemoglobin X, alpha-like embryonic chain in Hba complex | 0.017 | ||
| Gsc | goosecoid homeobox | 0.017 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.017 | ||
| Gas1 | growth arrest specific 1 | 0.016 | ||
| Sall1 | sal-like 1 (Drosophila) | 0.016 | ||
| Dlx5 | distal-less homeobox 5 | 0.016 | ||
| Bmp5 | bone morphogenetic protein 5 | 0.016 | ||
| Eda | ectodysplasin-A | 0.016 | ||
| Ephb2 | Eph receptor B2 | 0.015 | ||
| Spry4 | sprouty homolog 4 (Drosophila) | 0.015 | ||
| Psen1 | presenilin 1 | 0.015 | ||
| Npr3 | natriuretic peptide receptor 3 | 0.015 | ||
| Capn6 | calpain 6 | 0.015 | ||
| Ret | ret proto-oncogene | 0.015 | ||
| Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.015 | ||
| Tgfa | transforming growth factor alpha | 0.015 | ||
| Hoxd12 | homeobox D12 | 0.014 | ||
| Neurog3 | neurogenin 3 | 0.014 | ||
| Bmper | BMP-binding endothelial regulator | 0.014 | ||
| Mks1 | Meckel syndrome, type 1 | 0.014 | ||
| Lrp4 | low density lipoprotein receptor-related protein 4 | 0.014 | ||
| Nkx3-2 | NK3 homeobox 2 | 0.014 | ||
| Crlf1 | cytokine receptor-like factor 1 | 0.014 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.014 | ||
| Pax6 | paired box gene 6 | 0.014 | ||
| Rac1 | RAS-related C3 botulinum substrate 1 | 0.014 | ||
| Tjp1 | tight junction protein 1 | 0.014 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.013 | Human | |
| Sox2 | SRY-box containing gene 2 | 0.013 | ||
| Etv4 | ets variant gene 4 (E1A enhancer binding protein, E1AF) | 0.013 | ||
| Cdx1 | caudal type homeobox 1 | 0.013 | ||
| Rnf44 | ring finger protein 44 | 0.013 | ||
| Psmb7 | proteasome (prosome, macropain) subunit, beta type 7 | 0.013 | ||
| Dag1 | dystroglycan 1 | 0.013 | ||
| Sema5b | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B | 0.013 | ||
| Pmel | premelanosome protein | 0.013 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.013 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.013 | ||
| Crabp1 | cellular retinoic acid binding protein I | 0.013 | ||
| Nkx3-1 | NK-3 transcription factor, locus 1 (Drosophila) | 0.013 | ||
| Dppa5a | developmental pluripotency associated 5A | 0.013 | ||
| Dbn1 | drebrin 1 | 0.013 | ||
| Efna2 | ephrin A2 | 0.013 | ||
| Sp6 | trans-acting transcription factor 6 | 0.012 | ||
| Dot1l | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | 0.012 | ||
| Tssk1 | testis-specific serine kinase 1 | 0.012 | ||
| Lect2 | leukocyte cell-derived chemotaxin 2 | 0.012 | ||
| Tbx5 | T-box 5 | 0.012 | ||
| Actn3 | actinin alpha 3 | 0.012 | ||
| Gjb3 | gap junction protein, beta 3 | 0.012 | ||
| Lhx1 | LIM homeobox protein 1 | 0.012 | ||
| Mesp2 | mesoderm posterior 2 | 0.012 | Human | |
| Hes2 | hairy and enhancer of split 2 (Drosophila) | 0.012 | ||
| Ly6g6c | lymphocyte antigen 6 complex, locus G6C | 0.011 | ||
| Smad1 | MAD homolog 1 (Drosophila) | 0.011 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.011 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.011 | ||
| Galnt2 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 | 0.011 | ||
| Olfr70 | olfactory receptor 70 | 0.011 | ||
| Efna4 | ephrin A4 | 0.011 | ||
| Fgf8 | fibroblast growth factor 8 | 0.011 | ||
| Pax2 | paired box gene 2 | 0.011 | ||
| Gbx2 | gastrulation brain homeobox 2 | 0.011 | ||
| Yap1 | yes-associated protein 1 | 0.011 | ||
| Hoxa5 | homeobox A5 | 0.011 | ||
| Mtnr1a | melatonin receptor 1A | 0.011 | ||
| Fzd2 | frizzled homolog 2 (Drosophila) | 0.010 | ||
| Nrarp | Notch-regulated ankyrin repeat protein | 0.010 | ||
| Nkx6-1 | NK6 homeobox 1 | 0.010 | ||
| Hip1 | huntingtin interacting protein 1 | 0.010 | ||
| Hmga2 | high mobility group AT-hook 2 | 0.010 | ||
| Mnx1 | motor neuron and pancreas homeobox 1 | 0.010 | ||
| Nog | noggin | 0.010 | Human | |
| Rhox2a | reproductive homeobox 2A | 0.010 |