IMP

Process View

Mus musculus

4 genes annotated in mouse

regulation of plasminogen activation

Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of plasminogen activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of plasminogen activation" (in gray)

Name	Description	Probability	Func Analog Organism
Thbs2	thrombospondin 2	0.612
Cyr61	cysteine rich protein 61	0.538
Asgr2	asialoglycoprotein receptor 2	0.414
Ambp	alpha 1 microglobulin/bikunin	0.250
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.201
Plaur	plasminogen activator, urokinase receptor	0.201
Mat1a	methionine adenosyltransferase I, alpha	0.200
Apoa1	apolipoprotein A-I	0.168
F2	coagulation factor II	0.154
Wisp1	WNT1 inducible signaling pathway protein 1	0.141
Mdm2	transformed mouse 3T3 cell double minute 2	0.134
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.133
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.130
Atf3	activating transcription factor 3	0.124
Mbl2	mannose-binding lectin (protein C) 2	0.119	Mouse
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.115
Ces1c	carboxylesterase 1C	0.112
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.111
Fbln2	fibulin 2	0.109
Ctgf	connective tissue growth factor	0.103
Cxcl1	chemokine (C-X-C motif) ligand 1	0.097
Asgr1	asialoglycoprotein receptor 1	0.093
Cd44	CD44 antigen	0.093
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.090
Osmr	oncostatin M receptor	0.090
Msln	mesothelin	0.084
Pzp	pregnancy zone protein	0.083
Cpn1	carboxypeptidase N, polypeptide 1	0.073
Has1	hyaluronan synthase1	0.072
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.069
Plg	plasminogen	0.067
Ttc36	tetratricopeptide repeat domain 36	0.067
Rhox6	reproductive homeobox 6	0.064
Cxcl2	chemokine (C-X-C motif) ligand 2	0.063
Dpt	dermatopontin	0.062
1300017J02Rik	RIKEN cDNA 1300017J02 gene	0.060
Gdf15	growth differentiation factor 15	0.060
Hc	hemolytic complement	0.060
Ier3	immediate early response 3	0.059
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.058
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.058
Ptgs2	prostaglandin-endoperoxide synthase 2	0.058
Dio1	deiodinase, iodothyronine, type I	0.057
Fgg	fibrinogen gamma chain	0.055
Tnc	tenascin C	0.055
Fgb	fibrinogen beta chain	0.054
Mfap5	microfibrillar associated protein 5	0.053
Clic3	chloride intracellular channel 3	0.052
Kng1	kininogen 1	0.047
Hbegf	heparin-binding EGF-like growth factor	0.046
Gc	group specific component	0.046
Sdsl	serine dehydratase-like	0.045
Apoc4	apolipoprotein C-IV	0.045
Gm6484	predicted gene 6484	0.045
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.044
Ager	advanced glycosylation end product-specific receptor	0.043
Fgfr4	fibroblast growth factor receptor 4	0.042
Cfi	complement component factor i	0.042
Apom	apolipoprotein M	0.042
Agmat	agmatine ureohydrolase (agmatinase)	0.041
Bik	BCL2-interacting killer	0.041
Proc	protein C	0.040
Apoa4	apolipoprotein A-IV	0.040
Hpx	hemopexin	0.039
Gjb1	gap junction protein, beta 1	0.039
Foxa2	forkhead box A2	0.039
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.039
Sertad1	SERTA domain containing 1	0.038
Timp1	tissue inhibitor of metalloproteinase 1	0.038
Cldn3	claudin 3	0.037
F13b	coagulation factor XIII, beta subunit	0.036
Lipc	lipase, hepatic	0.035
Amdhd1	amidohydrolase domain containing 1	0.035
H1foo	H1 histone family, member O, oocyte-specific	0.035
Dusp1	dual specificity phosphatase 1	0.035
Prodh2	proline dehydrogenase (oxidase) 2	0.035
Klf6	Kruppel-like factor 6	0.034
Ahsg	alpha-2-HS-glycoprotein	0.034
Aqp8	aquaporin 8	0.033
Afm	afamin	0.033
Rdh7	retinol dehydrogenase 7	0.033
Fos	FBJ osteosarcoma oncogene	0.032
H2-M9	histocompatibility 2, M region locus 9	0.032
Adm	adrenomedullin	0.032
Rab25	RAB25, member RAS oncogene family	0.032
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.032
Tpm4	tropomyosin 4	0.031
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.031	Human
Hpn	hepsin	0.031	Human
Pah	phenylalanine hydroxylase	0.031
Col13a1	collagen, type XIII, alpha 1	0.031
Ccdc90b	coiled-coil domain containing 90B	0.031
Hnf1b	HNF1 homeobox B	0.030
Akr1c6	aldo-keto reductase family 1, member C6	0.030
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.030
Krt8	keratin 8	0.029
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.029
Ppic	peptidylprolyl isomerase C	0.029
Emp1	epithelial membrane protein 1	0.029
Hgfac	hepatocyte growth factor activator	0.028
Aadat	aminoadipate aminotransferase	0.028
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.028
Fga	fibrinogen alpha chain	0.028
C9	complement component 9	0.027
Apoa5	apolipoprotein A-V	0.027
Klk1b4	kallikrein 1-related pepidase b4	0.027
Jun	Jun oncogene	0.027
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.027
Col17a1	collagen, type XVII, alpha 1	0.027
Bhlhe40	basic helix-loop-helix family, member e40	0.026
Spg21	spastic paraplegia 21 homolog (human)	0.026
Cox8b	cytochrome c oxidase, subunit VIIIb	0.026
Junb	Jun-B oncogene	0.026
Rasl11b	RAS-like, family 11, member B	0.026
Agxt	alanine-glyoxylate aminotransferase	0.025
Proz	protein Z, vitamin K-dependent plasma glycoprotein	0.025
Csrp3	cysteine and glycine-rich protein 3	0.025
Wls	wntless homolog (Drosophila)	0.025
Cldn2	claudin 2	0.025
Cpn2	carboxypeptidase N, polypeptide 2	0.025
Pigr	polymeric immunoglobulin receptor	0.025
Ch25h	cholesterol 25-hydroxylase	0.024
Plunc	palate, lung, and nasal epithelium associated	0.023
Sftpb	surfactant associated protein B	0.023
Ccl2	chemokine (C-C motif) ligand 2	0.023
Apoa2	apolipoprotein A-II	0.023
Gyg	glycogenin	0.023
Litaf	LPS-induced TN factor	0.023
Apoh	apolipoprotein H	0.022
Rab17	RAB17, member RAS oncogene family	0.022
Emx1	empty spiracles homolog 1 (Drosophila)	0.022
C4bp	complement component 4 binding protein	0.022
Pbld1	phenazine biosynthesis-like protein domain containing 1	0.022
Wwtr1	WW domain containing transcription regulator 1	0.022
Procr	protein C receptor, endothelial	0.022
Zfp36	zinc finger protein 36	0.022
C8a	complement component 8, alpha polypeptide	0.022
Rgn	regucalcin	0.021
Magix	MAGI family member, X-linked	0.021
Vnn3	vanin 3	0.021
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.021
Col4a4	collagen, type IV, alpha 4	0.021
Pdpn	podoplanin	0.021
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.021
Tat	tyrosine aminotransferase	0.020
Sftpa1	surfactant associated protein A1	0.020	Mouse
F3	coagulation factor III	0.020
Wfdc2	WAP four-disulfide core domain 2	0.020
Igfbp1	insulin-like growth factor binding protein 1	0.019
Hgd	homogentisate 1, 2-dioxygenase	0.019
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.019
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.019
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.019
Gnmt	glycine N-methyltransferase	0.019
Ccl7	chemokine (C-C motif) ligand 7	0.018
Ivl	involucrin	0.018
Egr2	early growth response 2	0.018
Aldob	aldolase B, fructose-bisphosphate	0.018
Hes1	hairy and enhancer of split 1 (Drosophila)	0.018
Fst	follistatin	0.018
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.018
Orm1	orosomucoid 1	0.018
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.018
Orm2	orosomucoid 2	0.018
Mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.018
Habp2	hyaluronic acid binding protein 2	0.018
Cryab	crystallin, alpha B	0.017
Apcs	serum amyloid P-component	0.017
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.017
Cnn1	calponin 1	0.017
Itih2	inter-alpha trypsin inhibitor, heavy chain 2	0.017
Hnf4a	hepatic nuclear factor 4, alpha	0.017
Sftpd	surfactant associated protein D	0.017	Mouse
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.017
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.017
Spdef	SAM pointed domain containing ets transcription factor	0.017
Crp	C-reactive protein, pentraxin-related	0.017
Fam167b	family with sequence similarity 167, member B	0.017
Prss23	protease, serine, 23	0.017
Cd14	CD14 antigen	0.016
Btg2	B-cell translocation gene 2, anti-proliferative	0.016
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.016
Egr1	early growth response 1	0.016
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.016
Spp2	secreted phosphoprotein 2	0.016
Anxa3	annexin A3	0.016
Aadac	arylacetamide deacetylase (esterase)	0.016
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.016
Cfd	complement factor D (adipsin)	0.016
Ces1e	carboxylesterase 1E	0.016
C8g	complement component 8, gamma polypeptide	0.016
Areg	amphiregulin	0.016
Rhoc	ras homolog gene family, member C	0.016
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.015
Prph2	peripherin 2	0.015
Lgals3	lectin, galactose binding, soluble 3	0.015
Nlrp6	NLR family, pyrin domain containing 6	0.015
Cela1	chymotrypsin-like elastase family, member 1	0.015
Hp	haptoglobin	0.015
Clec4f	C-type lectin domain family 4, member f	0.015
F7	coagulation factor VII	0.015
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.015
Car5a	carbonic anhydrase 5a, mitochondrial	0.015
Socs3	suppressor of cytokine signaling 3	0.015
Mt4	metallothionein 4	0.014
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.014
Thbs1	thrombospondin 1	0.014	Human
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.014
Apof	apolipoprotein F	0.014
Sec14l2	SEC14-like 2 (S. cerevisiae)	0.014
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.014
Epha2	Eph receptor A2	0.014
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.014
Azgp1	alpha-2-glycoprotein 1, zinc	0.014
Rhoj	ras homolog gene family, member J	0.014
BC051019	cDNA sequence BC051019	0.014
Tmprss11e	transmembrane protease, serine 11e	0.014
Pvr	poliovirus receptor	0.014
Gcgr	glucagon receptor	0.014
Foxa1	forkhead box A1	0.014
Otc	ornithine transcarbamylase	0.014
Fabp1	fatty acid binding protein 1, liver	0.013
Muc5b	mucin 5, subtype B, tracheobronchial	0.013
Guca1a	guanylate cyclase activator 1a (retina)	0.013
Gadd45b	growth arrest and DNA-damage-inducible 45 beta	0.013
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.013
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.013
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.013
Jdp2	Jun dimerization protein 2	0.013
Inhbc	inhibin beta-C	0.013
Kazald1	Kazal-type serine peptidase inhibitor domain 1	0.013
Lmo4	LIM domain only 4	0.013
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.013
F10	coagulation factor X	0.013
Inhbe	inhibin beta E	0.013
Wnt5b	wingless-related MMTV integration site 5B	0.013
Cela2a	chymotrypsin-like elastase family, member 2A	0.013
Apob	apolipoprotein B	0.013
Tnxb	tenascin XB	0.013
Dmkn	dermokine	0.013
Mup3	major urinary protein 3	0.012
G6pc	glucose-6-phosphatase, catalytic	0.012
Apoc3	apolipoprotein C-III	0.012
Hrg	histidine-rich glycoprotein	0.012
C8b	complement component 8, beta polypeptide	0.012
Pdzk1	PDZ domain containing 1	0.012
Fxyd1	FXYD domain-containing ion transport regulator 1	0.012
U46068	cDNA sequence U46068	0.012
Hamp	hepcidin antimicrobial peptide	0.012
Cidec	cell death-inducing DFFA-like effector c	0.012
1700016K19Rik	RIKEN cDNA 1700016K19 gene	0.012
Shf	Src homology 2 domain containing F	0.012
Pcdh12	protocadherin 12	0.012
Dguok	deoxyguanosine kinase	0.012
Bcmo1	beta-carotene 15,15'-monooxygenase	0.012
F9	coagulation factor IX	0.012
Tfpi2	tissue factor pathway inhibitor 2	0.012
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.012
Ctsk	cathepsin K	0.011
Tmem37	transmembrane protein 37	0.011
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.011
Sftpc	surfactant associated protein C	0.011
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.011
Slc39a4	solute carrier family 39 (zinc transporter), member 4	0.011
Matn4	matrilin 4	0.011
Igfbp6	insulin-like growth factor binding protein 6	0.011
Kitl	kit ligand	0.011
Agrp	agouti related protein	0.011
S100a6	S100 calcium binding protein A6 (calcyclin)	0.011
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.011
Cldn7	claudin 7	0.011
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.011
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.011
Muc1	mucin 1, transmembrane	0.011
Saa4	serum amyloid A 4	0.011
Hal	histidine ammonia lyase	0.011
Il17d	interleukin 17D	0.010
Mrap	melanocortin 2 receptor accessory protein	0.010
Leprot	leptin receptor overlapping transcript	0.010
Il6st	interleukin 6 signal transducer	0.010
S100g	S100 calcium binding protein G	0.010
Pdzk1ip1	PDZK1 interacting protein 1	0.010
Tmprss2	transmembrane protease, serine 2	0.010
F11	coagulation factor XI	0.010
Sp5	trans-acting transcription factor 5	0.010
Psme1	proteasome (prosome, macropain) 28 subunit, alpha	0.010
Fhit	fragile histidine triad gene	0.010
Rasd1	RAS, dexamethasone-induced 1	0.010
Pfn2	profilin 2	0.010
Mbl1	mannose-binding lectin (protein A) 1	0.010	Mouse
Cd163l1	CD163 molecule-like 1	0.010