IMP

Process View

Mus musculus

17 genes annotated in mouse

positive regulation of mitochondrion organization

Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of mitochondrion organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of mitochondrion organization" (in gray)

Name	Description	Probability	Func Analog Organism
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	1.000	Human
Bax	BCL2-associated X protein	1.000	Human Worm
Bcl2	B-cell leukemia/lymphoma 2	0.996	Worm
Bak1	BCL2-antagonist/killer 1	0.990	Worm
Mcl1	myeloid cell leukemia sequence 1	0.926	Worm
Mfn2	mitofusin 2	0.894	Fly
Igh	immunoglobulin heavy chain complex	0.661
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.612
Axin1	axin 1	0.513
Lrrk2	leucine-rich repeat kinase 2	0.355
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.320
Trp53	transformation related protein 53	0.301	Human
Pdcd6ip	programmed cell death 6 interacting protein	0.282
Atxn2	ataxin 2	0.250
Cdk4	cyclin-dependent kinase 4	0.238
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.217	Human Fly
Stim2	stromal interaction molecule 2	0.217
Mdm2	transformed mouse 3T3 cell double minute 2	0.210
Mta1	metastasis associated 1	0.202
Phb2	prohibitin 2	0.181
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.159
Ppargc1b	peroxisome proliferative activated receptor, gamma, coactivator 1 beta	0.156	Mouse
Polr2h	polymerase (RNA) II (DNA directed) polypeptide H	0.147
Mrpl3	mitochondrial ribosomal protein L3	0.139
Timm8a1	translocase of inner mitochondrial membrane 8 homolog a1 (yeast)	0.131
Aim2	absent in melanoma 2	0.118
Ehd3	EH-domain containing 3	0.110
Tcrd	T-cell receptor delta chain	0.108
Becn1	beclin 1, autophagy related	0.103
Vhl	von Hippel-Lindau tumor suppressor	0.093
Bcl2l1	BCL2-like 1	0.082	Worm
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.081
Srrt	serrate RNA effector molecule homolog (Arabidopsis)	0.076
Ccnd1	cyclin D1	0.073
Casp1	caspase 1	0.070
Kit	kit oncogene	0.069
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.069
Myc	myelocytomatosis oncogene	0.058
Agtr2	angiotensin II receptor, type 2	0.058
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.057
Nos3	nitric oxide synthase 3, endothelial cell	0.055
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.049
Hmbs	hydroxymethylbilane synthase	0.048
Slc30a9	solute carrier family 30 (zinc transporter), member 9	0.048
Mdm4	transformed mouse 3T3 cell double minute 4	0.048
Afg3l2	AFG3(ATPase family gene 3)-like 2 (yeast)	0.045
Pparg	peroxisome proliferator activated receptor gamma	0.043
Klf6	Kruppel-like factor 6	0.041
Mrps2	mitochondrial ribosomal protein S2	0.040
Coq5	coenzyme Q5 homolog, methyltransferase (yeast)	0.040
Ncoa3	nuclear receptor coactivator 3	0.036
Setd8	SET domain containing (lysine methyltransferase) 8	0.035
Smn1	survival motor neuron 1	0.035
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.035
Notch2	Notch gene homolog 2 (Drosophila)	0.033
Kti12	KTI12 homolog, chromatin associated (S. cerevisiae)	0.030
2700094K13Rik	RIKEN cDNA 2700094K13 gene	0.030
Pten	phosphatase and tensin homolog	0.029
Atad3a	ATPase family, AAA domain containing 3A	0.029
Ttn	titin	0.028
Uqcc	ubiquinol-cytochrome c reductase complex chaperone, CBP3 homolog (yeast)	0.028
Lrpprc	leucine-rich PPR-motif containing	0.027
2510039O18Rik	RIKEN cDNA 2510039O18 gene	0.025
Cdk2ap1	CDK2 (cyclin-dependent kinase 2)-associated protein 1	0.025
Nampt	nicotinamide phosphoribosyltransferase	0.024
Vdac1	voltage-dependent anion channel 1	0.024
Usp10	ubiquitin specific peptidase 10	0.024
Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform	0.024
Gbp5	guanylate binding protein 5	0.024
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.023
Fastkd1	FAST kinase domains 1	0.023
Dnm1	dynamin 1	0.023
Chchd4	coiled-coil-helix-coiled-coil-helix domain containing 4	0.022
2410002F23Rik	RIKEN cDNA 2410002F23 gene	0.022
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.022
Hspd1	heat shock protein 1 (chaperonin)	0.021
Sncaip	synuclein, alpha interacting protein (synphilin)	0.021
Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	0.021
Pdk1	pyruvate dehydrogenase kinase, isoenzyme 1	0.020
Prkcz	protein kinase C, zeta	0.020
Cox18	COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)	0.020
2610024G14Rik	RIKEN cDNA 2610024G14 gene	0.020
Dap3	death associated protein 3	0.020
Naa10	N(alpha)-acetyltransferase 10, NatA catalytic subunitNalpha acetyltransferase 10	0.019
Mrps30	mitochondrial ribosomal protein S30	0.019
Lap3	leucine aminopeptidase 3	0.019
Ints5	integrator complex subunit 5	0.018
Hist1h1c	histone cluster 1, H1c	0.018
Ptp4a1	protein tyrosine phosphatase 4a1	0.018
Immt	inner membrane protein, mitochondrial	0.018
Wdr55	WD repeat domain 55	0.018
Hdgf	hepatoma-derived growth factor	0.017
Tchp	trichoplein, keratin filament binding	0.017
C1qbp	complement component 1, q subcomponent binding protein	0.017
Pptc7	PTC7 protein phosphatase homolog (S. cerevisiae)	0.017
Pgk1	phosphoglycerate kinase 1	0.017
Rxra	retinoid X receptor alpha	0.017
Bid	BH3 interacting domain death agonist	0.016
5730403B10Rik	RIKEN cDNA 5730403B10 gene	0.016
Ndrg2	N-myc downstream regulated gene 2	0.016
Ifrd2	interferon-related developmental regulator 2	0.016
Ikzf3	IKAROS family zinc finger 3	0.015
Lyst	lysosomal trafficking regulator	0.015
Galk1	galactokinase 1	0.015
Esrra	estrogen related receptor, alpha	0.015
Atxn7l3	ataxin 7-like 3	0.015
Dnaja3	DnaJ (Hsp40) homolog, subfamily A, member 3	0.014
Rab10	RAB10, member RAS oncogene family	0.014
Acd	adrenocortical dysplasia	0.014
Ddx19a	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a	0.014
Bach1	BTB and CNC homology 1	0.014
1700029G01Rik	RIKEN cDNA 1700029G01 gene	0.014
Lpin1	lipin 1	0.014
Pick1	protein interacting with C kinase 1	0.014
Rrn3	RRN3 RNA polymerase I transcription factor homolog (yeast)	0.014
Pdk2	pyruvate dehydrogenase kinase, isoenzyme 2	0.014
Bcl7c	B-cell CLL/lymphoma 7C	0.013
Ret	ret proto-oncogene	0.013
Acin1	apoptotic chromatin condensation inducer 1	0.013
2310030N02Rik	RIKEN cDNA 2310030N02 gene	0.013
Fam134b	family with sequence similarity 134, member B	0.013
Nup62	nucleoporin 62	0.013
Dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.013
Ccnd3	cyclin D3	0.013
Sdccag3	serologically defined colon cancer antigen 3	0.013
Cpsf4	cleavage and polyadenylation specific factor 4	0.013
G3bp1	Ras-GTPase-activating protein SH3-domain binding protein 1	0.013
Larp1	La ribonucleoprotein domain family, member 1	0.013
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.013
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.013
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.013
Pabpc4	poly(A) binding protein, cytoplasmic 4	0.013
Mfn1	mitofusin 1	0.012	Fly
Ndufa12	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12	0.012
Agl	amylo-1,6-glucosidase, 4-alpha-glucanotransferase	0.012
Mrpl10	mitochondrial ribosomal protein L10	0.012
Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.012
Ccrn4l	CCR4 carbon catabolite repression 4-like (S. cerevisiae)	0.012
U2af1	U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1	0.012
Mcart1	mitochondrial carrier triple repeat 1	0.012
Idh3a	isocitrate dehydrogenase 3 (NAD+) alpha	0.012
2310061I04Rik	RIKEN cDNA 2310061I04 gene	0.012
Ppif	peptidylprolyl isomerase F (cyclophilin F)	0.012
Uck2	uridine-cytidine kinase 2	0.011
Ikzf2	IKAROS family zinc finger 2	0.011
Adipor1	adiponectin receptor 1	0.011
Wt1	Wilms tumor 1 homolog	0.011
Rdh13	retinol dehydrogenase 13 (all-trans and 9-cis)	0.011
Opa1	optic atrophy 1 homolog (human)	0.011
Mrps5	mitochondrial ribosomal protein S5	0.011
Ugp2	UDP-glucose pyrophosphorylase 2	0.011
Mrpl51	mitochondrial ribosomal protein L51	0.011
Tcta	T-cell leukemia translocation altered gene	0.011
Eif4ebp1	eukaryotic translation initiation factor 4E binding protein 1	0.011
Alad	aminolevulinate, delta-, dehydratase	0.011
Pfn2	profilin 2	0.011
Rora	RAR-related orphan receptor alpha	0.011
Srm	spermidine synthase	0.011
March5	membrane-associated ring finger (C3HC4) 5	0.011	Human
Nsmce4a	non-SMC element 4 homolog A (S. cerevisiae)	0.010
Nme4	non-metastatic cells 4, protein expressed in	0.010
Prkci	protein kinase C, iota	0.010
Mtch2	mitochondrial carrier homolog 2 (C. elegans)	0.010
Gtf3a	general transcription factor III A	0.010
Wwox	WW domain-containing oxidoreductase	0.010
A430005L14Rik	RIKEN cDNA A430005L14 gene	0.010
Gfm1	G elongation factor, mitochondrial 1	0.010
Casp3	caspase 3	0.010
Ufsp1	UFM1-specific peptidase 1	0.010
Rcl1	RNA terminal phosphate cyclase-like 1	0.010
Max	Max protein	0.010