IMP
Process View
positive regulation of metalloenzyme activity
Any process that activates, maintains or increases the rate activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of metalloenzyme activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ptrf | polymerase I and transcript release factor | 0.887 | ||
| Rac1 | RAS-related C3 botulinum substrate 1 | 0.869 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.612 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.510 | ||
| Lepr | leptin receptor | 0.403 | ||
| Psen1 | presenilin 1 | 0.284 | ||
| Pak1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.276 | ||
| Apoe | apolipoprotein E | 0.273 | ||
| Tlr4 | toll-like receptor 4 | 0.224 | ||
| Vegfa | vascular endothelial growth factor A | 0.200 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.180 | ||
| Dmd | dystrophin, muscular dystrophy | 0.143 | ||
| Steap3 | STEAP family member 3 | 0.136 | ||
| Nos1 | nitric oxide synthase 1, neuronal | 0.128 | ||
| Lox | lysyl oxidase | 0.127 | ||
| Ghr | growth hormone receptor | 0.116 | ||
| Slc39a4 | solute carrier family 39 (zinc transporter), member 4 | 0.108 | ||
| Slc31a1 | solute carrier family 31, member 1 | 0.099 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.093 | ||
| Lep | leptin | 0.091 | ||
| Cd44 | CD44 antigen | 0.082 | ||
| Sdcbp | syndecan binding protein | 0.076 | ||
| Gja1 | gap junction protein, alpha 1 | 0.069 | ||
| Insr | insulin receptor | 0.067 | ||
| Actr3 | ARP3 actin-related protein 3 homolog (yeast) | 0.065 | ||
| Sh3bgrl | SH3-binding domain glutamic acid-rich protein like | 0.061 | ||
| Rnd3 | Rho family GTPase 3 | 0.058 | ||
| Fbn1 | fibrillin 1 | 0.057 | ||
| Plin1 | perilipin 1 | 0.053 | ||
| Pten | phosphatase and tensin homolog | 0.049 | ||
| Sgca | sarcoglycan, alpha (dystrophin-associated glycoprotein) | 0.049 | ||
| Ldlr | low density lipoprotein receptor | 0.048 | ||
| Lipe | lipase, hormone sensitive | 0.048 | ||
| Kl | klotho | 0.046 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.043 | ||
| Adipoq | adiponectin, C1Q and collagen domain containing | 0.042 | ||
| Egfr | epidermal growth factor receptor | 0.038 | ||
| Ctnna1 | catenin (cadherin associated protein), alpha 1 | 0.034 | ||
| Cd36 | CD36 antigen | 0.033 | ||
| Tmod3 | tropomodulin 3 | 0.033 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.031 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.029 | ||
| Lmna | lamin A | 0.029 | ||
| Adam10 | a disintegrin and metallopeptidase domain 10 | 0.029 | ||
| Capza2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.029 | ||
| Lpin1 | lipin 1 | 0.026 | ||
| Nptn | neuroplastin | 0.025 | ||
| Rhoa | ras homolog gene family, member A | 0.025 | ||
| Shroom1 | shroom family member 1 | 0.025 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.024 | ||
| Marcks | myristoylated alanine rich protein kinase C substrate | 0.024 | ||
| Sdpr | serum deprivation response | 0.023 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.023 | ||
| Tmem123 | transmembrane protein 123 | 0.023 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.022 | ||
| Cav1 | caveolin 1, caveolae protein | 0.022 | ||
| Stx7 | syntaxin 7 | 0.021 | ||
| Lrrk2 | leucine-rich repeat kinase 2 | 0.020 | ||
| Sept7 | septin 7 | 0.020 | ||
| Rod1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.019 | ||
| Dync1i2 | dynein cytoplasmic 1 intermediate chain 2 | 0.019 | ||
| Foxa2 | forkhead box A2 | 0.019 | ||
| Phldb2 | pleckstrin homology-like domain, family B, member 2 | 0.019 | ||
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.018 | ||
| Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.018 | ||
| Snx6 | sorting nexin 6 | 0.018 | ||
| 2810428I15Rik | RIKEN cDNA 2810428I15 gene | 0.017 | ||
| Bcl10 | B-cell leukemia/lymphoma 10 | 0.016 | ||
| Lamp2 | lysosomal-associated membrane protein 2 | 0.016 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.016 | ||
| Stk3 | serine/threonine kinase 3 (Ste20, yeast homolog) | 0.016 | ||
| Npc1 | Niemann Pick type C1 | 0.016 | ||
| Timm13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.015 | ||
| Atox1 | ATX1 (antioxidant protein 1) homolog 1 (yeast) | 0.015 | ||
| Pcdh12 | protocadherin 12 | 0.014 | ||
| Idua | iduronidase, alpha-L- | 0.014 | ||
| Cdhr5 | cadherin-related family member 5 | 0.014 | ||
| Crb3 | crumbs homolog 3 (Drosophila) | 0.014 | ||
| Stra13 | stimulated by retinoic acid 13 | 0.014 | ||
| Esr2 | estrogen receptor 2 (beta) | 0.014 | ||
| Cidec | cell death-inducing DFFA-like effector c | 0.014 | ||
| Plau | plasminogen activator, urokinase | 0.014 | ||
| Pklr | pyruvate kinase liver and red blood cell | 0.013 | ||
| Pik3cb | phosphatidylinositol 3-kinase, catalytic, beta polypeptide | 0.013 | ||
| Park2 | Parkinson disease (autosomal recessive, juvenile) 2, parkin | 0.013 | ||
| Numb | numb gene homolog (Drosophila) | 0.013 | ||
| Nr1h3 | nuclear receptor subfamily 1, group H, member 3 | 0.013 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.013 | ||
| Efemp2 | epidermal growth factor-containing fibulin-like extracellular matrix protein 2 | 0.012 | ||
| Chad | chondroadherin | 0.012 | ||
| Vdr | vitamin D receptor | 0.012 | ||
| Dctpp1 | dCTP pyrophosphatase 1 | 0.012 | ||
| Gnai3 | guanine nucleotide binding protein (G protein), alpha inhibiting 3 | 0.012 | ||
| Mobkl1b | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.012 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.012 | ||
| Hnf1b | HNF1 homeobox B | 0.012 | ||
| Dusp1 | dual specificity phosphatase 1 | 0.012 | ||
| Wls | wntless homolog (Drosophila) | 0.012 | ||
| Spink4 | serine peptidase inhibitor, Kazal type 4 | 0.012 | ||
| Pgam2 | phosphoglycerate mutase 2 | 0.012 | ||
| Nudt1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 0.012 | ||
| Sgcg | sarcoglycan, gamma (dystrophin-associated glycoprotein) | 0.012 | ||
| Art1 | ADP-ribosyltransferase 1 | 0.011 | ||
| Wsb1 | WD repeat and SOCS box-containing 1 | 0.011 | ||
| Thrb | thyroid hormone receptor beta | 0.011 | ||
| Arhgap1 | Rho GTPase activating protein 1 | 0.011 | ||
| Lama2 | laminin, alpha 2 | 0.011 | ||
| Ar | androgen receptor | 0.011 | ||
| Gsk3b | glycogen synthase kinase 3 beta | 0.011 | ||
| Cldn3 | claudin 3 | 0.011 | ||
| Hif3a | hypoxia inducible factor 3, alpha subunit | 0.011 | ||
| Cox8b | cytochrome c oxidase, subunit VIIIb | 0.010 | ||
| Gna11 | guanine nucleotide binding protein, alpha 11 | 0.010 | ||
| Hmbs | hydroxymethylbilane synthase | 0.010 | ||
| Chst3 | carbohydrate (chondroitin 6/keratan) sulfotransferase 3 | 0.010 |