IMP

Process View

Mus musculus

10 genes annotated in mouse

decidualization

The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "decidualization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "decidualization" (in gray)

Name	Description	Probability	Func Analog Organism
Ptgs2	prostaglandin-endoperoxide synthase 2	0.937
Fos	FBJ osteosarcoma oncogene	0.842
Csf1	colony stimulating factor 1 (macrophage)	0.747
Lepr	leptin receptor	0.614
Egr1	early growth response 1	0.572
Nos3	nitric oxide synthase 3, endothelial cell	0.432
Apc	adenomatosis polyposis coli	0.343
Nos2	nitric oxide synthase 2, inducible	0.326
Ahr	aryl-hydrocarbon receptor	0.260
Smad3	MAD homolog 3 (Drosophila)	0.258
Ar	androgen receptor	0.230
Fshr	follicle stimulating hormone receptor	0.216
Esr2	estrogen receptor 2 (beta)	0.134
Prlr	prolactin receptor	0.127
Amhr2	anti-Mullerian hormone type 2 receptor	0.124
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.081
Atf3	activating transcription factor 3	0.070
Mapk8	mitogen-activated protein kinase 8	0.070
Ctsl	cathepsin L	0.069
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.067
Cyr61	cysteine rich protein 61	0.064
Kiss1	KiSS-1 metastasis-suppressor	0.060
Lgmn	legumain	0.052
Tyrobp	TYRO protein tyrosine kinase binding protein	0.049
Dusp1	dual specificity phosphatase 1	0.049
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.047
Pten	phosphatase and tensin homolog	0.045
Stat3	signal transducer and activator of transcription 3	0.045
Ppt1	palmitoyl-protein thioesterase 1	0.044
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.043
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.042
Thbs1	thrombospondin 1	0.041
Ctsb	cathepsin B	0.041
Cav1	caveolin 1, caveolae protein	0.039
Ctnnb1	catenin (cadherin associated protein), beta 1	0.039
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.038
Igf1	insulin-like growth factor 1	0.035
Egr2	early growth response 2	0.033
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.032
Cd247	CD247 antigen	0.032
Notch2	Notch gene homolog 2 (Drosophila)	0.031
Pgr	progesterone receptor	0.030
Ltbp1	latent transforming growth factor beta binding protein 1	0.029
Smad4	MAD homolog 4 (Drosophila)	0.027
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.027
Prkce	protein kinase C, epsilon	0.027
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.027
Ren1	renin 1 structural	0.026
Csf1r	colony stimulating factor 1 receptor	0.026
Gnrh1	gonadotropin releasing hormone 1	0.024
Slc12a1	solute carrier family 12, member 1	0.024
Col1a1	collagen, type I, alpha 1	0.023
Vhl	von Hippel-Lindau tumor suppressor	0.023
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.022
Plau	plasminogen activator, urokinase	0.021
C1qb	complement component 1, q subcomponent, beta polypeptide	0.021
Atp5d	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	0.021
Timp1	tissue inhibitor of metalloproteinase 1	0.021
Hr	hairless	0.021
Axl	AXL receptor tyrosine kinase	0.020
Jun	Jun oncogene	0.019	Mouse
Il6	interleukin 6	0.019
Pparg	peroxisome proliferator activated receptor gamma	0.019
Mgrn1	mahogunin, ring finger 1	0.019
Lamp2	lysosomal-associated membrane protein 2	0.019
Irs2	insulin receptor substrate 2	0.018
Dsg4	desmoglein 4	0.018
Ghr	growth hormone receptor	0.018
Nos1	nitric oxide synthase 1, neuronal	0.018
Foxn1	forkhead box N1	0.017
Itgb3	integrin beta 3	0.017
Sqstm1	sequestosome 1	0.016
Junb	Jun-B oncogene	0.016
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.016
Plat	plasminogen activator, tissue	0.015
Zfp36	zinc finger protein 36	0.015
Rhob	ras homolog gene family, member B	0.015
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.015
Adra1b	adrenergic receptor, alpha 1b	0.014
C1qc	complement component 1, q subcomponent, C chain	0.014
Mapk14	mitogen-activated protein kinase 14	0.014
Kit	kit oncogene	0.014
Inhba	inhibin beta-A	0.014
Egfr	epidermal growth factor receptor	0.013
Bhlhe40	basic helix-loop-helix family, member e40	0.013
Sertad1	SERTA domain containing 1	0.013
Mapk1	mitogen-activated protein kinase 1	0.013
Agtr1a	angiotensin II receptor, type 1a	0.013
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.013
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.012
Fcgr3	Fc receptor, IgG, low affinity III	0.012
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.012
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.012
Ier3	immediate early response 3	0.012
Gsdma3	gasdermin A3	0.012
Invs	inversin	0.012
Ttc7	tetratricopeptide repeat domain 7	0.012
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.012
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.012
Stk11	serine/threonine kinase 11	0.011
Vegfa	vascular endothelial growth factor A	0.011
Klf6	Kruppel-like factor 6	0.011
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.011
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.011
Gja1	gap junction protein, alpha 1	0.011
Bglap	bone gamma carboxyglutamate protein	0.011
Tcrd	T-cell receptor delta chain	0.011
Adm	adrenomedullin	0.010
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.010