IMP

Process View

Mus musculus

1 genes annotated in mouse

Multi-species View

negative regulation of cardiac chamber formation

GO:1901211

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cardiac chamber formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of cardiac chamber formation" (in gray)

Name	Description	Probability	Func Analog Organism
Tbx3	T-box 3	0.999	Mouse
Pitx2	paired-like homeodomain transcription factor 2	0.988
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.983
Shh	sonic hedgehog	0.954
Fgfr2	fibroblast growth factor receptor 2	0.948
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.918
Hoxa1	homeobox A1	0.918
Tcfap2a	transcription factor AP-2, alpha	0.907
Tbx5	T-box 5	0.876	Mouse
Pitx1	paired-like homeodomain transcription factor 1	0.853
Scn5a	sodium channel, voltage-gated, type V, alpha	0.829
Foxc2	forkhead box C2	0.733
Prrx1	paired related homeobox 1	0.712
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.703
Eya1	eyes absent 1 homolog (Drosophila)	0.655
Pax2	paired box gene 2	0.651
Foxg1	forkhead box G1	0.647
Hand2	heart and neural crest derivatives expressed transcript 2	0.646
Bmp4	bone morphogenetic protein 4	0.606
Pax3	paired box gene 3	0.605
Msx1	homeobox, msh-like 1	0.572
Fgf8	fibroblast growth factor 8	0.513
Foxc1	forkhead box C1	0.503
Sox9	SRY-box containing gene 9	0.443
Jag1	jagged 1	0.396
Hand1	heart and neural crest derivatives expressed transcript 1	0.387
Gli3	GLI-Kruppel family member GLI3	0.385
Otx2	orthodenticle homolog 2 (Drosophila)	0.360
Chd7	chromodomain helicase DNA binding protein 7	0.338
Dlx5	distal-less homeobox 5	0.323
Gja5	gap junction protein, alpha 5	0.257
Fgf10	fibroblast growth factor 10	0.242
Rarg	retinoic acid receptor, gamma	0.237
Chrd	chordin	0.226
Zeb1	zinc finger E-box binding homeobox 1	0.225
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.220
Vangl2	vang-like 2 (van gogh, Drosophila)	0.204
Tbx1	T-box 1	0.197	Mouse
Tbx4	T-box 4	0.170	Mouse
Sall4	sal-like 4 (Drosophila)	0.169
Wnt3a	wingless-related MMTV integration site 3A	0.167
Nanog	Nanog homeobox	0.165
Gsc	goosecoid homeobox	0.163
Lrp6	low density lipoprotein receptor-related protein 6	0.162
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.159
Lmx1a	LIM homeobox transcription factor 1 alpha	0.156
Fgfr1	fibroblast growth factor receptor 1	0.148
Gata4	GATA binding protein 4	0.146
Rarb	retinoic acid receptor, beta	0.140
Hoxa3	homeobox A3	0.140
Ighmbp2	immunoglobulin mu binding protein 2	0.133
Lef1	lymphoid enhancer binding factor 1	0.133
Smo	smoothened homolog (Drosophila)	0.125
Ednra	endothelin receptor type A	0.122
Gbx2	gastrulation brain homeobox 2	0.115
Vegfa	vascular endothelial growth factor A	0.108
Rxra	retinoid X receptor alpha	0.106
Emx2	empty spiracles homolog 2 (Drosophila)	0.104
Sox2	SRY-box containing gene 2	0.103
Runx2	runt related transcription factor 2	0.102
Hoxa2	homeobox A2	0.101
Alx1	ALX homeobox 1	0.099
Efnb2	ephrin B2	0.093
Tcf21	transcription factor 21	0.091
Wt1	Wilms tumor 1 homolog	0.088
Smad6	MAD homolog 6 (Drosophila)	0.084
Gdnf	glial cell line derived neurotrophic factor	0.084
Dll4	delta-like 4 (Drosophila)	0.081
Gata6	GATA binding protein 6	0.080
Fgfr3	fibroblast growth factor receptor 3	0.078
Gata3	GATA binding protein 3	0.072
Hoxa13	homeobox A13	0.061
Ece1	endothelin converting enzyme 1	0.060
Pax9	paired box gene 9	0.060
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.059
Dlx2	distal-less homeobox 2	0.058
Hmx3	H6 homeobox 3	0.057
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.057
Bmp7	bone morphogenetic protein 7	0.056
Tgfb2	transforming growth factor, beta 2	0.056
Msx2	homeobox, msh-like 2	0.052
Irx3	Iroquois related homeobox 3 (Drosophila)	0.051
Prrx2	paired related homeobox 2	0.050
Bmp5	bone morphogenetic protein 5	0.050
Otx1	orthodenticle homolog 1 (Drosophila)	0.050
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.049
Trp63	transformation related protein 63	0.046
Emx1	empty spiracles homolog 1 (Drosophila)	0.044
Col13a1	collagen, type XIII, alpha 1	0.043
Pbx1	pre B-cell leukemia transcription factor 1	0.042
Zic3	zinc finger protein of the cerebellum 3	0.040
Gata5	GATA binding protein 5	0.039
Foxf1a	forkhead box F1a	0.038
Pou5f1	POU domain, class 5, transcription factor 1	0.038
Acvr1	activin A receptor, type 1	0.037
Lrp5	low density lipoprotein receptor-related protein 5	0.036
Wnt5a	wingless-related MMTV integration site 5A	0.034
Isl1	ISL1 transcription factor, LIM/homeodomain	0.034
Pcdh12	protocadherin 12	0.033
Gli2	GLI-Kruppel family member GLI2	0.033
Hoxd1	homeobox D1	0.032
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.032
Hoxb3	homeobox B3	0.031
Prdm6	PR domain containing 6	0.031
Twist2	twist homolog 2 (Drosophila)	0.031
Mn1	meningioma 1	0.030
Nodal	nodal	0.029
Hoxa11	homeobox A11	0.027
Gata2	GATA binding protein 2	0.026
Snai1	snail homolog 1 (Drosophila)	0.025
Nog	noggin	0.025
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.025
Cxadr	coxsackie virus and adenovirus receptor	0.025
Hoxd3	homeobox D3	0.025
Sall1	sal-like 1 (Drosophila)	0.024
Rnf2	ring finger protein 2	0.024
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.023
Bdnf	brain derived neurotrophic factor	0.023
Fgf3	fibroblast growth factor 3	0.023
Tbx2	T-box 2	0.023
Alx4	aristaless-like homeobox 4	0.023
Nkx3-2	NK3 homeobox 2	0.022
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.021
Tlx3	T-cell leukemia, homeobox 3	0.021
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.021
Rara	retinoic acid receptor, alpha	0.021
Bnc1	basonuclin 1	0.020
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.019
Hoxa10	homeobox A10	0.019
Foxi1	forkhead box I1	0.019
Hoxb2	homeobox B2	0.019
Shox2	short stature homeobox 2	0.018
Tbx20	T-box 20	0.018	Mouse
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.017
Hoxd11	homeobox D11	0.017
Cdx2	caudal type homeobox 2	0.017
Hmx2	H6 homeobox 2	0.017
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.016
Xirp1	xin actin-binding repeat containing 1	0.016
Dnahc5	dynein, axonemal, heavy chain 5	0.016
Myf5	myogenic factor 5	0.016
Irx4	Iroquois related homeobox 4 (Drosophila)	0.016
Ryr2	ryanodine receptor 2, cardiac	0.016
Sox11	SRY-box containing gene 11	0.016
Noto	notochord homolog (Xenopus laevis)	0.015
Hoxb4	homeobox B4	0.015
Nkg7	natural killer cell group 7 sequence	0.015
Pax7	paired box gene 7	0.015
Atoh8	atonal homolog 8 (Drosophila)	0.015
Prdm1	PR domain containing 1, with ZNF domain	0.015
Foxf2	forkhead box F2	0.015
Bcl6	B-cell leukemia/lymphoma 6	0.015
Hoxd13	homeobox D13	0.015
Tnfrsf25	tumor necrosis factor receptor superfamily, member 25	0.014
Mesp1	mesoderm posterior 1	0.014
T	brachyury	0.014	Mouse
Foxa1	forkhead box A1	0.014
Fev	FEV (ETS oncogene family)	0.014
Mecom	MDS1 and EVI1 complex locus	0.014
Satb2	special AT-rich sequence binding protein 2	0.014
Pou4f2	POU domain, class 4, transcription factor 2	0.014
Sox17	SRY-box containing gene 17	0.014
Hes7	hairy and enhancer of split 7 (Drosophila)	0.014
BC020535	cDNA sequence BC020535	0.014
Msc	musculin	0.014
She	src homology 2 domain-containing transforming protein E	0.014
Sox7	SRY-box containing gene 7	0.013
Ebf3	early B-cell factor 3	0.013
Tal1	T-cell acute lymphocytic leukemia 1	0.013
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.013
Klf14	Kruppel-like factor 14	0.013
Ripply3	ripply3 homolog (zebrafish)	0.013
Foxb1	forkhead box B1	0.012
Asb10	ankyrin repeat and SOCS box-containing 10	0.012
Hoxa4	homeobox A4	0.012
Wnt1	wingless-related MMTV integration site 1	0.012
Pou4f3	POU domain, class 4, transcription factor 3	0.012
Foxh1	forkhead box H1	0.012
Isl2	insulin related protein 2 (islet 2)	0.012
Hoxd9	homeobox D9	0.012
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.012
En1	engrailed 1	0.012
Rybp	RING1 and YY1 binding protein	0.012
Mnx1	motor neuron and pancreas homeobox 1	0.012
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.011
Olig3	oligodendrocyte transcription factor 3	0.011
Irx5	Iroquois related homeobox 5 (Drosophila)	0.011
Runx3	runt related transcription factor 3	0.011
Alx3	aristaless-like homeobox 3	0.011
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.011
Fgfrl1	fibroblast growth factor receptor-like 1	0.011
Nckap5l	NCK-associated protein 5-like	0.011
Pax1	paired box gene 1	0.011
Dlx6	distal-less homeobox 6	0.011
Mta1	metastasis associated 1	0.011
Tead1	TEA domain family member 1	0.011
Foxi3	forkhead box I3	0.011
Hs3st3b1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	0.011
Zfpm2	zinc finger protein, multitype 2	0.011
Sim2	single-minded homolog 2 (Drosophila)	0.011
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.010
Apc	adenomatosis polyposis coli	0.010
Hspa12b	heat shock protein 12B	0.010
Hoxb1	homeobox B1	0.010
Axin2	axin2	0.010
Ntn3	netrin 3	0.010
Capn6	calpain 6	0.010
Hoxd8	homeobox D8	0.010
Meox2	mesenchyme homeobox 2	0.010