IMP

Process View

Mus musculus

4 genes annotated in mouse

negative regulation of branching involved in ureteric bud morphogenesis

Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of branching involved in ureteric bud morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of branching involved in ureteric bud morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.998
Eya1	eyes absent 1 homolog (Drosophila)	0.997
Chrd	chordin	0.977
Bmp4	bone morphogenetic protein 4	0.966
Fgfr2	fibroblast growth factor receptor 2	0.961
Msx1	homeobox, msh-like 1	0.958
Fgfr1	fibroblast growth factor receptor 1	0.950
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.948
Pax3	paired box gene 3	0.936
Prrx1	paired related homeobox 1	0.934
Foxc1	forkhead box C1	0.926
Tcfap2a	transcription factor AP-2, alpha	0.918
Tbx1	T-box 1	0.911
Smo	smoothened homolog (Drosophila)	0.872
Fgf8	fibroblast growth factor 8	0.861
Gli3	GLI-Kruppel family member GLI3	0.830
Foxc2	forkhead box C2	0.812
Tgfb2	transforming growth factor, beta 2	0.782
Hand2	heart and neural crest derivatives expressed transcript 2	0.721
Prrx2	paired related homeobox 2	0.707
Pax2	paired box gene 2	0.676
Hand1	heart and neural crest derivatives expressed transcript 1	0.675
Rarg	retinoic acid receptor, gamma	0.665
Ednra	endothelin receptor type A	0.620
Bmp7	bone morphogenetic protein 7	0.618
Sox9	SRY-box containing gene 9	0.611
Pitx2	paired-like homeodomain transcription factor 2	0.611
Dlx5	distal-less homeobox 5	0.594
Hoxa1	homeobox A1	0.528
Nodal	nodal	0.486
Hoxa2	homeobox A2	0.446
Otx2	orthodenticle homolog 2 (Drosophila)	0.441
Gsc	goosecoid homeobox	0.414
Gbx2	gastrulation brain homeobox 2	0.362
Foxg1	forkhead box G1	0.354
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.341
Msx2	homeobox, msh-like 2	0.289
Pbx1	pre B-cell leukemia transcription factor 1	0.257
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.240
Fgf10	fibroblast growth factor 10	0.234
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.233	Mouse
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.231
Rarb	retinoic acid receptor, beta	0.220
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.209
Gli2	GLI-Kruppel family member GLI2	0.186
Acvr1	activin A receptor, type 1	0.184
Zeb1	zinc finger E-box binding homeobox 1	0.178
Isl1	ISL1 transcription factor, LIM/homeodomain	0.169
Sox2	SRY-box containing gene 2	0.167
Jag1	jagged 1	0.162
Hoxa3	homeobox A3	0.155
Fgf3	fibroblast growth factor 3	0.128
Ece1	endothelin converting enzyme 1	0.109
Pax6	paired box gene 6	0.099
Fgfr3	fibroblast growth factor receptor 3	0.096
Vegfa	vascular endothelial growth factor A	0.095
Meox2	mesenchyme homeobox 2	0.094
Nog	noggin	0.089
Rara	retinoic acid receptor, alpha	0.087
Tgfbr2	transforming growth factor, beta receptor II	0.084
Pax9	paired box gene 9	0.081
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.073
Hoxd11	homeobox D11	0.073
Lhx1	LIM homeobox protein 1	0.069
Runx2	runt related transcription factor 2	0.068
Sall4	sal-like 4 (Drosophila)	0.062
Chd7	chromodomain helicase DNA binding protein 7	0.060
Zic3	zinc finger protein of the cerebellum 3	0.059
Foxh1	forkhead box H1	0.058
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.052
Otx1	orthodenticle homolog 1 (Drosophila)	0.050
Hes1	hairy and enhancer of split 1 (Drosophila)	0.049
Alx4	aristaless-like homeobox 4	0.049
Foxi3	forkhead box I3	0.045
Pax8	paired box gene 8	0.044
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.044
Emx2	empty spiracles homolog 2 (Drosophila)	0.043
Fbln1	fibulin 1	0.042
Dlx2	distal-less homeobox 2	0.036
Dlx6	distal-less homeobox 6	0.035
En1	engrailed 1	0.034
Tcfap2c	transcription factor AP-2, gamma	0.034
Lrp2	low density lipoprotein receptor-related protein 2	0.032
Ddr2	discoidin domain receptor family, member 2	0.031
Vangl2	vang-like 2 (van gogh, Drosophila)	0.031
Gata3	GATA binding protein 3	0.031
Myf5	myogenic factor 5	0.029
Hoxa11	homeobox A11	0.029
Tbx15	T-box 15	0.028
Efnb2	ephrin B2	0.026
Hoxa9	homeobox A9	0.026
Hoxd13	homeobox D13	0.025
Gas1	growth arrest specific 1	0.023
Mmp11	matrix metallopeptidase 11	0.023
Gdf3	growth differentiation factor 3	0.023	Mouse
Col2a1	collagen, type II, alpha 1	0.022
Pitx1	paired-like homeodomain transcription factor 1	0.022
Wt1	Wilms tumor 1 homolog	0.022
Hoxb3	homeobox B3	0.022
Bmp2	bone morphogenetic protein 2	0.021	Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.021
Gata4	GATA binding protein 4	0.021
Tbx10	T-box 10	0.021
Rxra	retinoid X receptor alpha	0.021
Hoxd3	homeobox D3	0.020
T	brachyury	0.020
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.019
Hoxa5	homeobox A5	0.019
Disp1	dispatched homolog 1 (Drosophila)	0.019
Dlx1	distal-less homeobox 1	0.018
Wnt3a	wingless-related MMTV integration site 3A	0.018
Alx3	aristaless-like homeobox 3	0.018
Mesp1	mesoderm posterior 1	0.018
Hbb-bh1	hemoglobin Z, beta-like embryonic chain	0.018
Hoxa10	homeobox A10	0.017
Ptch1	patched homolog 1	0.017
Sox11	SRY-box containing gene 11	0.017
Mn1	meningioma 1	0.017
Mecom	MDS1 and EVI1 complex locus	0.017
Tead4	TEA domain family member 4	0.016
Lrp6	low density lipoprotein receptor-related protein 6	0.016
Sox4	SRY-box containing gene 4	0.016
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.016
Matn3	matrilin 3	0.016
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.015
Bnc1	basonuclin 1	0.015
Wfdc2	WAP four-disulfide core domain 2	0.015
Yap1	yes-associated protein 1	0.015
Gpc3	glypican 3	0.015
Tcf21	transcription factor 21	0.014
Alx1	ALX homeobox 1	0.014
Smad6	MAD homolog 6 (Drosophila)	0.014
Myf6	myogenic factor 6	0.014
Foxf1a	forkhead box F1a	0.014
Foxd1	forkhead box D1	0.014
Gata6	GATA binding protein 6	0.014
Eomes	eomesodermin homolog (Xenopus laevis)	0.014
Gdf1	growth differentiation factor 1	0.014	Mouse
Krt14	keratin 14	0.014
Hes5	hairy and enhancer of split 5 (Drosophila)	0.013
Hoxc4	homeobox C4	0.013
Tdgf1	teratocarcinoma-derived growth factor 1	0.013
Foxa2	forkhead box A2	0.013
Tbx3	T-box 3	0.013
Nanog	Nanog homeobox	0.013
Tcf15	transcription factor 15	0.013
Ntf3	neurotrophin 3	0.013
Rhag	Rhesus blood group-associated A glycoprotein	0.013
Hoxd9	homeobox D9	0.013
Il11	interleukin 11	0.012
Tead3	TEA domain family member 3	0.012
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.012
Lefty1	left right determination factor 1	0.012
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.012
Ctf1	cardiotrophin 1	0.012
Twist2	twist homolog 2 (Drosophila)	0.012
Myl7	myosin, light polypeptide 7, regulatory	0.012
Eya2	eyes absent 2 homolog (Drosophila)	0.011
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.011
Hoxb4	homeobox B4	0.011
Ptk2	PTK2 protein tyrosine kinase 2	0.011
Pax1	paired box gene 1	0.011
Lef1	lymphoid enhancer binding factor 1	0.011
Cdh1	cadherin 1	0.011
Tshz1	teashirt zinc finger family member 1	0.011
Pthlh	parathyroid hormone-like peptide	0.011
Wnt5a	wingless-related MMTV integration site 5A	0.011
Psen1	presenilin 1	0.011
Ppl	periplakin	0.011
Foxf2	forkhead box F2	0.011
Actn3	actinin alpha 3	0.011
Aes	amino-terminal enhancer of split	0.011
Neurog1	neurogenin 1	0.011
Wnt3	wingless-related MMTV integration site 3	0.011
Gjb5	gap junction protein, beta 5	0.011
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.011
Hoxc8	homeobox C8	0.011
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.011	Mouse
Hoxb13	homeobox B13	0.011
Cldn8	claudin 8	0.010
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.010
Gjb4	gap junction protein, beta 4	0.010
Wnt4	wingless-related MMTV integration site 4	0.010
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.010
Tnni2	troponin I, skeletal, fast 2	0.010