IMP

Process View

Mus musculus

9 genes annotated in mouse

negative regulation of muscle cell apoptotic process

Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of muscle cell apoptotic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of muscle cell apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
Hand2	heart and neural crest derivatives expressed transcript 2	0.998
Shh	sonic hedgehog	0.982
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.977
Isl1	ISL1 transcription factor, LIM/homeodomain	0.940
Fgf8	fibroblast growth factor 8	0.879
Foxc2	forkhead box C2	0.839
Hand1	heart and neural crest derivatives expressed transcript 1	0.832	Mouse
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.777
Pax3	paired box gene 3	0.774
Pten	phosphatase and tensin homolog	0.767
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.737
Tgfbr2	transforming growth factor, beta receptor II	0.664
Otx2	orthodenticle homolog 2 (Drosophila)	0.657
Hoxa1	homeobox A1	0.585
Nos3	nitric oxide synthase 3, endothelial cell	0.553
Vegfa	vascular endothelial growth factor A	0.505
Foxg1	forkhead box G1	0.453
Foxc1	forkhead box C1	0.448
Pax6	paired box gene 6	0.414
Ntf3	neurotrophin 3	0.413
Tcfap2a	transcription factor AP-2, alpha	0.384
Gata4	GATA binding protein 4	0.331
Emx1	empty spiracles homolog 1 (Drosophila)	0.286
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.257
Efnb2	ephrin B2	0.254
Neurog2	neurogenin 2	0.244	Mouse
Msx1	homeobox, msh-like 1	0.231
Tgfb2	transforming growth factor, beta 2	0.228
Kiss1	KiSS-1 metastasis-suppressor	0.222
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.201
Neurod1	neurogenic differentiation 1	0.179	Mouse
Bmp4	bone morphogenetic protein 4	0.179
Ptf1a	pancreas specific transcription factor, 1a	0.167	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.162
Mecom	MDS1 and EVI1 complex locus	0.151
Sox11	SRY-box containing gene 11	0.148
Gbx2	gastrulation brain homeobox 2	0.137
Rxra	retinoid X receptor alpha	0.128
Tbx5	T-box 5	0.125
Gli2	GLI-Kruppel family member GLI2	0.107
Chd7	chromodomain helicase DNA binding protein 7	0.106
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.105
En1	engrailed 1	0.105
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.104
Gsc	goosecoid homeobox	0.102
Phox2b	paired-like homeobox 2b	0.100
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.093
Hes5	hairy and enhancer of split 5 (Drosophila)	0.092
Sfrp1	secreted frizzled-related protein 1	0.091	Mouse
Eya1	eyes absent 1 homolog (Drosophila)	0.089
Socs1	suppressor of cytokine signaling 1	0.089
Tbx1	T-box 1	0.084
Agtr1a	angiotensin II receptor, type 1a	0.079
Grb10	growth factor receptor bound protein 10	0.075
Ctnnb1	catenin (cadherin associated protein), beta 1	0.074
Ednra	endothelin receptor type A	0.070
Acvr1	activin A receptor, type 1	0.068
Sfrp2	secreted frizzled-related protein 2	0.068
Jag1	jagged 1	0.068
Fgfr1	fibroblast growth factor receptor 1	0.064
Zeb1	zinc finger E-box binding homeobox 1	0.063
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.063
Fbn1	fibrillin 1	0.060
Chrd	chordin	0.060
Ghr	growth hormone receptor	0.058
Pitx1	paired-like homeodomain transcription factor 1	0.057
Neurod4	neurogenic differentiation 4	0.053	Mouse
Pax9	paired box gene 9	0.053
Alx3	aristaless-like homeobox 3	0.053
Pou4f2	POU domain, class 4, transcription factor 2	0.053
Bdkrb2	bradykinin receptor, beta 2	0.052	Mouse
Gata1	GATA binding protein 1	0.049
Meox2	mesenchyme homeobox 2	0.048
T	brachyury	0.047
Prrx2	paired related homeobox 2	0.045
Lepr	leptin receptor	0.044
Sox9	SRY-box containing gene 9	0.043
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.040
Nhlh1	nescient helix loop helix 1	0.040	Mouse
Insm1	insulinoma-associated 1	0.040
Vangl2	vang-like 2 (van gogh, Drosophila)	0.038
Sox2	SRY-box containing gene 2	0.038
Pdx1	pancreatic and duodenal homeobox 1	0.037
Lox	lysyl oxidase	0.035
Neurog3	neurogenin 3	0.035	Mouse
Bdnf	brain derived neurotrophic factor	0.035
Mesp1	mesoderm posterior 1	0.034
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.034
Pou4f3	POU domain, class 4, transcription factor 3	0.033
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.032
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.031
Prrx1	paired related homeobox 1	0.030
Pthlh	parathyroid hormone-like peptide	0.030
Fgf15	fibroblast growth factor 15	0.030
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.029
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.028
Tal1	T-cell acute lymphocytic leukemia 1	0.027	Mouse
Tcf21	transcription factor 21	0.027
Egfr	epidermal growth factor receptor	0.027
Smo	smoothened homolog (Drosophila)	0.026
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.026
Cdh23	cadherin 23 (otocadherin)	0.026
Ldlr	low density lipoprotein receptor	0.024
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.024
Ebf2	early B-cell factor 2	0.023
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.023
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.023
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.023	Mouse
Igf2	insulin-like growth factor 2	0.022
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.021
Adam17	a disintegrin and metallopeptidase domain 17	0.020
Trp53	transformation related protein 53	0.020
Pitx2	paired-like homeodomain transcription factor 2	0.020
Prph2	peripherin 2	0.020
Nog	noggin	0.019
Gja1	gap junction protein, alpha 1	0.019
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.019
Hoxd13	homeobox D13	0.019
Lep	leptin	0.018
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.018
Tcf15	transcription factor 15	0.018	Mouse
Pax2	paired box gene 2	0.018
Gata6	GATA binding protein 6	0.018
Tbx20	T-box 20	0.017
Prox1	prospero-related homeobox 1	0.017
Zfhx4	zinc finger homeodomain 4	0.017
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.017
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.017
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.016
Vax1	ventral anterior homeobox containing gene 1	0.016
Pcdh12	protocadherin 12	0.016
Sox1	SRY-box containing gene 1	0.016
Ren1	renin 1 structural	0.016
Ece1	endothelin converting enzyme 1	0.016
Nkx3-2	NK3 homeobox 2	0.016	Mouse
Atoh7	atonal homolog 7 (Drosophila)	0.016	Mouse
Gsk3b	glycogen synthase kinase 3 beta	0.015
Sfrp5	secreted frizzled-related sequence protein 5	0.015	Mouse
Rb1	retinoblastoma 1	0.015
Lmx1b	LIM homeobox transcription factor 1 beta	0.015
Tgfbr1	transforming growth factor, beta receptor I	0.015
Rpl7	ribosomal protein L7	0.015
Fgf17	fibroblast growth factor 17	0.015
Epha3	Eph receptor A3	0.014
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.014
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.014
Ret	ret proto-oncogene	0.014
Nkx6-1	NK6 homeobox 1	0.014
Neurog1	neurogenin 1	0.013	Mouse
Phox2a	paired-like homeobox 2a	0.013
Meox1	mesenchyme homeobox 1	0.013
Hoxd12	homeobox D12	0.013
Lhx5	LIM homeobox protein 5	0.013
Atoh1	atonal homolog 1 (Drosophila)	0.013	Mouse
Sox10	SRY-box containing gene 10	0.013
Runx2	runt related transcription factor 2	0.013
Nrk	Nik related kinase	0.013
Nrp1	neuropilin 1	0.013
Snai1	snail homolog 1 (Drosophila)	0.012
Nodal	nodal	0.012
Gp9	glycoprotein 9 (platelet)	0.012
Nppc	natriuretic peptide type C	0.012
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.012
Col22a1	collagen, type XXII, alpha 1	0.012
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.012
Gdnf	glial cell line derived neurotrophic factor	0.012
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.012
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.012
Tbx3	T-box 3	0.012
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.011
Wnt6	wingless-related MMTV integration site 6	0.011
Epor	erythropoietin receptor	0.011
Col1a1	collagen, type I, alpha 1	0.011
Eln	elastin	0.011
Csf1	colony stimulating factor 1 (macrophage)	0.011
Hes3	hairy and enhancer of split 3 (Drosophila)	0.011
Mpl	myeloproliferative leukemia virus oncogene	0.011
Notch1	Notch gene homolog 1 (Drosophila)	0.011
Hic1	hypermethylated in cancer 1	0.010
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.010	Rat