IMP

Process View

Mus musculus

9 genes annotated in mouse

Multi-species View

monocyte differentiation

GO:0030224

The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "monocyte differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "monocyte differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Fos	FBJ osteosarcoma oncogene	0.936
Pten	phosphatase and tensin homolog	0.908
Fgfr2	fibroblast growth factor receptor 2	0.893
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.759
Tgfb1	transforming growth factor, beta 1	0.693
Hdac4	histone deacetylase 4	0.537
Nos3	nitric oxide synthase 3, endothelial cell	0.525
Sp1	trans-acting transcription factor 1	0.498	Mouse
Trp53	transformation related protein 53	0.415
Mapk8	mitogen-activated protein kinase 8	0.398
Rb1	retinoblastoma 1	0.358
Ier2	immediate early response 2	0.346
Vegfa	vascular endothelial growth factor A	0.341	Human
Mndal	myeloid nuclear differentiation antigen like	0.335
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.334
Foxc1	forkhead box C1	0.322
Col1a1	collagen, type I, alpha 1	0.268
Egr1	early growth response 1	0.261
Shc1	src homology 2 domain-containing transforming protein C1	0.252
Tgfbr2	transforming growth factor, beta receptor II	0.246
Lepr	leptin receptor	0.246
Dusp1	dual specificity phosphatase 1	0.204
Mef2c	myocyte enhancer factor 2C	0.203
Sp3	trans-acting transcription factor 3	0.190
Csf1r	colony stimulating factor 1 receptor	0.166
Runx2	runt related transcription factor 2	0.165
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.146
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.141
Lmna	lamin A	0.129
Cav1	caveolin 1, caveolae protein	0.127
Ctnnb1	catenin (cadherin associated protein), beta 1	0.120
Notch2	Notch gene homolog 2 (Drosophila)	0.118
Hdac5	histone deacetylase 5	0.104
Egfr	epidermal growth factor receptor	0.096
Mapk14	mitogen-activated protein kinase 14	0.096
Alkbh1	alkB, alkylation repair homolog 1 (E. coli)	0.091
Yap1	yes-associated protein 1	0.086
Apoe	apolipoprotein E	0.083
Zfp36	zinc finger protein 36	0.082
Rev3l	REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)	0.078
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.077
Meox2	mesenchyme homeobox 2	0.073
Nos1	nitric oxide synthase 1, neuronal	0.068
Tal1	T-cell acute lymphocytic leukemia 1	0.067
Gata6	GATA binding protein 6	0.065
Tgfb2	transforming growth factor, beta 2	0.063
Kdm6a	4lysine (K)-specific demethylase 6A	0.058
Jag1	jagged 1	0.058
Shh	sonic hedgehog	0.056
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.052
Zfp148	zinc finger protein 148	0.050
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.048
Gja1	gap junction protein, alpha 1	0.048
Ptgs2	prostaglandin-endoperoxide synthase 2	0.048
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.047
Stat3	signal transducer and activator of transcription 3	0.045
Btg2	B-cell translocation gene 2, anti-proliferative	0.044
Acvr1	activin A receptor, type 1	0.043
Vdr	vitamin D receptor	0.043
Runx1	runt related transcription factor 1	0.042
Midn	midnolin	0.041
Ncoa6	nuclear receptor coactivator 6	0.040
Rxra	retinoid X receptor alpha	0.040
Fgf8	fibroblast growth factor 8	0.039
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.035
Fli1	Friend leukemia integration 1	0.035
Runx3	runt related transcription factor 3	0.034
Csf1	colony stimulating factor 1 (macrophage)	0.034
Hif1a	hypoxia inducible factor 1, alpha subunit	0.034
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.033
Max	Max protein	0.032
Klhl24	kelch-like 24 (Drosophila)	0.031
Apc	adenomatosis polyposis coli	0.030
Nf1	neurofibromatosis 1	0.029
Nrp1	neuropilin 1	0.028
Fzd4	frizzled homolog 4 (Drosophila)	0.027
Tbx1	T-box 1	0.027
Rhob	ras homolog gene family, member B	0.027
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.027
Hand2	heart and neural crest derivatives expressed transcript 2	0.026
Gata4	GATA binding protein 4	0.026
Klf6	Kruppel-like factor 6	0.026
Qk	quaking	0.026
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.026
Mef2d	myocyte enhancer factor 2D	0.025	Mouse
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.025
Thra	thyroid hormone receptor alpha	0.025
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.024
Pparg	peroxisome proliferator activated receptor gamma	0.023	Human
Ptp4a2	protein tyrosine phosphatase 4a2	0.023
Sox9	SRY-box containing gene 9	0.022
Kit	kit oncogene	0.022
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.022
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.022
Ptk2	PTK2 protein tyrosine kinase 2	0.021
Rarb	retinoic acid receptor, beta	0.021
Zeb1	zinc finger E-box binding homeobox 1	0.021
Il10ra	interleukin 10 receptor, alpha	0.021
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.021
Mpo	myeloperoxidase	0.021
Plin1	perilipin 1	0.020
Pitx2	paired-like homeodomain transcription factor 2	0.020
Sox4	SRY-box containing gene 4	0.020
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.020
Dusp2	dual specificity phosphatase 2	0.019
Foxp1	forkhead box P1	0.019
Ednra	endothelin receptor type A	0.019
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.019
Sell	selectin, lymphocyte	0.019
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.018
Kdr	kinase insert domain protein receptor	0.018
Spnb2	spectrin beta 2	0.017
Actn1	actinin, alpha 1	0.016
Nlrp3	NLR family, pyrin domain containing 3	0.016
Spn	sialophorin	0.016
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.015
Gfi1b	growth factor independent 1B	0.015
Vangl2	vang-like 2 (van gogh, Drosophila)	0.015
Zeb2	zinc finger E-box binding homeobox 2	0.015
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.015
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.015
Tcf4	transcription factor 4	0.015
Kitl	kit ligand	0.015
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.015
AI607873	expressed sequence AI607873	0.015
Ghr	growth hormone receptor	0.014
Jun	Jun oncogene	0.014
Egr2	early growth response 2	0.014
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.014
Cd300a	CD300A antigen	0.013
Ccl4	chemokine (C-C motif) ligand 4	0.013
Trpm7	transient receptor potential cation channel, subfamily M, member 7	0.013
Adipoq	adiponectin, C1Q and collagen domain containing	0.013
Arhgap30	Rho GTPase activating protein 30	0.013
Fgfr3	fibroblast growth factor receptor 3	0.013
Klf3	Kruppel-like factor 3 (basic)	0.013
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.013
Ccr2	chemokine (C-C motif) receptor 2	0.013
Zfp322a	zinc finger protein 322A	0.012
Msl2	male-specific lethal 2 homolog (Drosophila)	0.012
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.012
Vav1	vav 1 oncogene	0.012
Ahr	aryl-hydrocarbon receptor	0.012
Irs2	insulin receptor substrate 2	0.012
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.012
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.012
Rest	RE1-silencing transcription factor	0.011
Gadd45b	growth arrest and DNA-damage-inducible 45 beta	0.011
Foxc2	forkhead box C2	0.011
Il7r	interleukin 7 receptor	0.011
Cbl	Casitas B-lineage lymphoma	0.011
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.011
Mapk11	mitogen-activated protein kinase 11	0.011
Ikzf1	IKAROS family zinc finger 1	0.011
Rara	retinoic acid receptor, alpha	0.011
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.011
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.010
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.010
Cytip	cytohesin 1 interacting protein	0.010
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.010
Xrn1	5'-3' exoribonuclease 1	0.010
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.010