IMP

Process View

Mus musculus

4 genes annotated in mouse

positive regulation of phosphatase activity

Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of phosphatase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of phosphatase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Nos3	nitric oxide synthase 3, endothelial cell	0.739
Lepr	leptin receptor	0.626
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.540	Mouse
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.485
Hdac4	histone deacetylase 4	0.280
Ppargc1b	peroxisome proliferative activated receptor, gamma, coactivator 1 beta	0.168
Agtr2	angiotensin II receptor, type 2	0.110	Human
Mef2c	myocyte enhancer factor 2C	0.107
Tgfbr2	transforming growth factor, beta receptor II	0.104
Lrp1	low density lipoprotein receptor-related protein 1	0.102
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.096
Acvr1	activin A receptor, type 1	0.095
Pparg	peroxisome proliferator activated receptor gamma	0.082
Hdac5	histone deacetylase 5	0.074
Tlr2	toll-like receptor 2	0.071
Zeb2	zinc finger E-box binding homeobox 2	0.066
Ren1	renin 1 structural	0.063
Tgfb2	transforming growth factor, beta 2	0.058
Mef2d	myocyte enhancer factor 2D	0.055	Mouse
Casp8	caspase 8	0.052
Nos1	nitric oxide synthase 1, neuronal	0.050
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.047
Bcl2	B-cell leukemia/lymphoma 2	0.047
Igbp1	immunoglobulin (CD79A) binding protein 1	0.047
Agtr1a	angiotensin II receptor, type 1a	0.046
Cd44	CD44 antigen	0.043
Ldlr	low density lipoprotein receptor	0.042
Cav1	caveolin 1, caveolae protein	0.042
Elf1	E74-like factor 1	0.035
Fas	Fas (TNF receptor superfamily member 6)	0.034
Apc	adenomatosis polyposis coli	0.032
Ncoa3	nuclear receptor coactivator 3	0.030
Sh2b1	SH2B adaptor protein 1	0.029
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.029
Jak1	Janus kinase 1	0.028
Ttn	titin	0.028
Ptgs2	prostaglandin-endoperoxide synthase 2	0.028
Il6st	interleukin 6 signal transducer	0.027
Mas1	MAS1 oncogene	0.027
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.026
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.026
Pdgfb	platelet derived growth factor, B polypeptide	0.025
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.025
Fbn1	fibrillin 1	0.024
Gucy1a3	guanylate cyclase 1, soluble, alpha 3	0.023
Axin1	axin 1	0.023
Foxc1	forkhead box C1	0.023
Fyn	Fyn proto-oncogene	0.022
Hdac7	histone deacetylase 7	0.022
Ate1	arginyltransferase 1	0.022
Stat5b	signal transducer and activator of transcription 5B	0.022
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.022
Ptprc	protein tyrosine phosphatase, receptor type, C	0.021
Acvr2a	activin receptor IIA	0.021
Jag1	jagged 1	0.021
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.020
Col1a1	collagen, type I, alpha 1	0.020
Lims1	LIM and senescent cell antigen-like domains 1	0.020
Lamb2	laminin, beta 2	0.019
Socs3	suppressor of cytokine signaling 3	0.019
Iqcb1	IQ calmodulin-binding motif containing 1	0.019
Ifngr2	interferon gamma receptor 2	0.018
Smad1	MAD homolog 1 (Drosophila)	0.018
Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)	0.018
Cast	calpastatin	0.018
Kit	kit oncogene	0.017
Thra	thyroid hormone receptor alpha	0.017
Klf7	Kruppel-like factor 7 (ubiquitous)	0.017
Hipk3	homeodomain interacting protein kinase 3	0.017
Tgfb1	transforming growth factor, beta 1	0.017
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.017
Cdk14	cyclin-dependent kinase 14	0.016
Jun	Jun oncogene	0.016
Fli1	Friend leukemia integration 1	0.016
Rap1b	RAS related protein 1b	0.016
Ncor2	nuclear receptor co-repressor 2	0.016
Vegfa	vascular endothelial growth factor A	0.016
Esr1	estrogen receptor 1 (alpha)	0.016
Gja1	gap junction protein, alpha 1	0.016
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.015
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.015
6230424C14Rik	RIKEN cDNA 6230424C14 gene	0.015
Notch2	Notch gene homolog 2 (Drosophila)	0.015
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.014
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.014
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.014
Pcna	proliferating cell nuclear antigen	0.014
Tgfbr1	transforming growth factor, beta receptor I	0.014
Bmp7	bone morphogenetic protein 7	0.014
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.013
Rpgrip1l	Rpgrip1-like	0.013
Leprel2	leprecan-like 2	0.013
Smu1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	0.013
Camk2d	calcium/calmodulin-dependent protein kinase II, delta	0.013
Pten	phosphatase and tensin homolog	0.013
Rora	RAR-related orphan receptor alpha	0.013
Col4a3	collagen, type IV, alpha 3	0.013
Vdr	vitamin D receptor	0.013
Nfix	nuclear factor I/X	0.013
Cd86	CD86 antigen	0.013
Ltbp1	latent transforming growth factor beta binding protein 1	0.013
Col4a1	collagen, type IV, alpha 1	0.013
Vav3	vav 3 oncogene	0.013
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.013
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.013
Cep290	centrosomal protein 290	0.013
Vldlr	very low density lipoprotein receptor	0.012
Cirh1a	cirrhosis, autosomal recessive 1A (human)	0.012
Ptprb	protein tyrosine phosphatase, receptor type, B	0.012
Irs1	insulin receptor substrate 1	0.012
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.012
Myb	myeloblastosis oncogene	0.012
Smad2	MAD homolog 2 (Drosophila)	0.012
Wipf1	WAS/WASL interacting protein family, member 1	0.012
Mlkl	mixed lineage kinase domain-like	0.012
Zfand5	zinc finger, AN1-type domain 5	0.012
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.012
Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	0.012
Qk	quaking	0.012
Ptgs1	prostaglandin-endoperoxide synthase 1	0.012
6330503K22Rik	RIKEN cDNA 6330503K22 gene	0.012
Ar	androgen receptor	0.012
Sh3kbp1	SH3-domain kinase binding protein 1	0.012
Ints5	integrator complex subunit 5	0.012
Klf6	Kruppel-like factor 6	0.011
Kif1b	kinesin family member 1B	0.011
Adipoq	adiponectin, C1Q and collagen domain containing	0.011
Tmem173	transmembrane protein 173	0.011
Usp25	ubiquitin specific peptidase 25	0.011
Cd53	CD53 antigen	0.011
Ptch1	patched homolog 1	0.011
Lmo7	LIM domain only 7	0.011
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.011
Slc20a1	solute carrier family 20, member 1	0.011
Klhl6	kelch-like 6 (Drosophila)	0.011
Smad7	MAD homolog 7 (Drosophila)	0.011
Prrx1	paired related homeobox 1	0.011
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.011
Ank	progressive ankylosis	0.011
Osbpl8	oxysterol binding protein-like 8	0.011
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.010
Esrra	estrogen related receptor, alpha	0.010
Wdr43	WD repeat domain 43	0.010
Ncoa1	nuclear receptor coactivator 1	0.010
Rasgrp3	RAS, guanyl releasing protein 3	0.010
Prkacb	protein kinase, cAMP dependent, catalytic, beta	0.010
Dhx16	DEAH (Asp-Glu-Ala-His) box polypeptide 16	0.010
Snrk	SNF related kinase	0.010