IMP

Process View

Mus musculus

10 genes annotated in mouse

prostatic bud formation

The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "prostatic bud formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "prostatic bud formation" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Gli3	GLI-Kruppel family member GLI3	1.000	Mouse
Pax2	paired box gene 2	0.999
Fgfr2	fibroblast growth factor receptor 2	0.996
Fgf10	fibroblast growth factor 10	0.988
Wnt3a	wingless-related MMTV integration site 3A	0.987	Mouse
Nodal	nodal	0.985	Mouse
Bmp7	bone morphogenetic protein 7	0.927
Fgfr3	fibroblast growth factor receptor 3	0.925
Hoxa13	homeobox A13	0.893
Bmp4	bone morphogenetic protein 4	0.824
Trp63	transformation related protein 63	0.781
Fgf8	fibroblast growth factor 8	0.752
Foxc1	forkhead box C1	0.744
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.740
Nog	noggin	0.726
Lhx1	LIM homeobox protein 1	0.716
Pax8	paired box gene 8	0.701
Ar	androgen receptor	0.609
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.606
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.568
Alx4	aristaless-like homeobox 4	0.494
Msx1	homeobox, msh-like 1	0.493
Emx2	empty spiracles homolog 2 (Drosophila)	0.486
Rarb	retinoic acid receptor, beta	0.476
Hoxd13	homeobox D13	0.465
Lmx1a	LIM homeobox transcription factor 1 alpha	0.462
Hoxd11	homeobox D11	0.450
Gli2	GLI-Kruppel family member GLI2	0.438
Sox9	SRY-box containing gene 9	0.433
Tbx3	T-box 3	0.421
Chrd	chordin	0.413
Prrx1	paired related homeobox 1	0.373
Tbx15	T-box 15	0.335
Rarg	retinoic acid receptor, gamma	0.324
Fgfr1	fibroblast growth factor receptor 1	0.323
Hoxa11	homeobox A11	0.277
Tbx1	T-box 1	0.255
Wnt9b	wingless-type MMTV integration site 9B	0.243	Mouse
Tcf21	transcription factor 21	0.237
Dlx5	distal-less homeobox 5	0.235
Prrx2	paired related homeobox 2	0.226
Fgf18	fibroblast growth factor 18	0.204
Pthlh	parathyroid hormone-like peptide	0.202
Amhr2	anti-Mullerian hormone type 2 receptor	0.187
Pitx2	paired-like homeodomain transcription factor 2	0.169
Pax3	paired box gene 3	0.169
Otx2	orthodenticle homolog 2 (Drosophila)	0.143
Msx2	homeobox, msh-like 2	0.138
Apc	adenomatosis polyposis coli	0.138
Gli1	GLI-Kruppel family member GLI1	0.133	Mouse
Foxf1a	forkhead box F1a	0.121
Foxh1	forkhead box H1	0.120
Fgf5	fibroblast growth factor 5	0.118	Mouse
Hoxa10	homeobox A10	0.115
Gata5	GATA binding protein 5	0.111
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.111
Smo	smoothened homolog (Drosophila)	0.108
Wt1	Wilms tumor 1 homolog	0.106
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.105
Gdf1	growth differentiation factor 1	0.100	Mouse
Fgf15	fibroblast growth factor 15	0.100
Angpt4	angiopoietin 4	0.095
Gbx2	gastrulation brain homeobox 2	0.095
Pten	phosphatase and tensin homolog	0.092
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.091
Ret	ret proto-oncogene	0.086
Wnt6	wingless-related MMTV integration site 6	0.083	Mouse
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.081
Twist2	twist homolog 2 (Drosophila)	0.077
Gsc	goosecoid homeobox	0.075
Meox2	mesenchyme homeobox 2	0.072
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.072
Fgf9	fibroblast growth factor 9	0.071	Mouse
Pou3f3	POU domain, class 3, transcription factor 3	0.071
Otx1	orthodenticle homolog 1 (Drosophila)	0.070
Npr3	natriuretic peptide receptor 3	0.066
Fzd8	frizzled homolog 8 (Drosophila)	0.064
Fzd1	frizzled homolog 1 (Drosophila)	0.063
Amh	anti-Mullerian hormone	0.063
Neurog3	neurogenin 3	0.063
Smad6	MAD homolog 6 (Drosophila)	0.061
Ptch1	patched homolog 1	0.059
Emx1	empty spiracles homolog 1 (Drosophila)	0.057
Ctnnb1	catenin (cadherin associated protein), beta 1	0.056
Wnt10b	wingless related MMTV integration site 10b	0.053	Mouse
Efna4	ephrin A4	0.053
Hand1	heart and neural crest derivatives expressed transcript 1	0.052
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.051
Wnt3	wingless-related MMTV integration site 3	0.051	Mouse
Gpc3	glypican 3	0.048
Lef1	lymphoid enhancer binding factor 1	0.047
Tbx2	T-box 2	0.046
Tgfb2	transforming growth factor, beta 2	0.043
Zic3	zinc finger protein of the cerebellum 3	0.043
Acvr1	activin A receptor, type 1	0.043
Gas1	growth arrest specific 1	0.042
Nkx2-1	NK2 homeobox 1	0.042
Bdkrb2	bradykinin receptor, beta 2	0.042
Gdnf	glial cell line derived neurotrophic factor	0.041
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.041
T	brachyury	0.040
Sox7	SRY-box containing gene 7	0.039
Wnt2b	wingless related MMTV integration site 2b	0.038	Mouse
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.038
Bmper	BMP-binding endothelial regulator	0.035
Omp	olfactory marker protein	0.032
Acan	aggrecan	0.032
Wnt4	wingless-related MMTV integration site 4	0.032	Mouse
Gja3	gap junction protein, alpha 3	0.031
Rspo1	R-spondin homolog (Xenopus laevis)	0.030
Zfpm2	zinc finger protein, multitype 2	0.030
Rara	retinoic acid receptor, alpha	0.030
Hoxd9	homeobox D9	0.030
Hoxb6	homeobox B6	0.029
Col4a3	collagen, type IV, alpha 3	0.029
Btbd17	BTB (POZ) domain containing 17	0.028
Cdx1	caudal type homeobox 1	0.027
Tdgf1	teratocarcinoma-derived growth factor 1	0.027
Pkdcc	protein kinase domain containing, cytoplasmic	0.027
Pbx1	pre B-cell leukemia transcription factor 1	0.026
Gata6	GATA binding protein 6	0.025
Pitx1	paired-like homeodomain transcription factor 1	0.025
Fgf3	fibroblast growth factor 3	0.024	Mouse
Barx1	BarH-like homeobox 1	0.024
Wnt9a	wingless-type MMTV integration site 9A	0.024	Mouse
Tcf15	transcription factor 15	0.024
En1	engrailed 1	0.023
Foxc2	forkhead box C2	0.023
Rxra	retinoid X receptor alpha	0.023
Col2a1	collagen, type II, alpha 1	0.023
Eya1	eyes absent 1 homolog (Drosophila)	0.022
Tgfbr3	transforming growth factor, beta receptor III	0.021
Mgat3	mannoside acetylglucosaminyltransferase 3	0.021
Epha1	Eph receptor A1	0.021
Foxd2	forkhead box D2	0.021
Foxb1	forkhead box B1	0.021
Pou3f1	POU domain, class 3, transcription factor 1	0.020
Zeb1	zinc finger E-box binding homeobox 1	0.020
Rem1	rad and gem related GTP binding protein 1	0.020
Foxf2	forkhead box F2	0.020
Chrdl2	chordin-like 2	0.020
Trp73	transformation related protein 73	0.020	Mouse
Sh3pxd2a	SH3 and PX domains 2A	0.020
Hmx3	H6 homeobox 3	0.019
Lmx1b	LIM homeobox transcription factor 1 beta	0.019
Cfc1	cripto, FRL-1, cryptic family 1	0.019
Jag2	jagged 2	0.019
Lrp2	low density lipoprotein receptor-related protein 2	0.019
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.019
Wnt7b	wingless-related MMTV integration site 7B	0.018	Mouse
Fzd7	frizzled homolog 7 (Drosophila)	0.018
Fgfrl1	fibroblast growth factor receptor-like 1	0.018
Padi3	peptidyl arginine deiminase, type III	0.018
Adra2b	adrenergic receptor, alpha 2b	0.018
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.018
Des	desmin	0.018
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.018
Col13a1	collagen, type XIII, alpha 1	0.018
Adra1a	adrenergic receptor, alpha 1a	0.018
Fzd4	frizzled homolog 4 (Drosophila)	0.017
Edn3	endothelin 3	0.017
Dlx4	distal-less homeobox 4	0.017
Bmp5	bone morphogenetic protein 5	0.016	Mouse
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.016
Gata4	GATA binding protein 4	0.016
Hoxa2	homeobox A2	0.016
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.016
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.015
Vax1	ventral anterior homeobox containing gene 1	0.015
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.015
Ptch2	patched homolog 2	0.015
Cdh16	cadherin 16	0.015
Pax7	paired box gene 7	0.015
Axin2	axin2	0.015
Kcnk3	potassium channel, subfamily K, member 3	0.015
Sox2	SRY-box containing gene 2	0.014
Alx1	ALX homeobox 1	0.014
Hand2	heart and neural crest derivatives expressed transcript 2	0.014
Nos3	nitric oxide synthase 3, endothelial cell	0.014
Otp	orthopedia homolog (Drosophila)	0.014
Epha4	Eph receptor A4	0.013
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.013
Eya4	eyes absent 4 homolog (Drosophila)	0.013
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.013
Sfrp1	secreted frizzled-related protein 1	0.013
Fgfbp1	fibroblast growth factor binding protein 1	0.013
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.012
Runx2	runt related transcription factor 2	0.012
Wnt5a	wingless-related MMTV integration site 5A	0.012
Trp53	transformation related protein 53	0.012	Mouse
Sox3	SRY-box containing gene 3	0.012
Hoxc9	homeobox C9	0.012
Col12a1	collagen, type XII, alpha 1	0.012
Smyd1	SET and MYND domain containing 1	0.012
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.012
Pgr	progesterone receptor	0.012
Lrp6	low density lipoprotein receptor-related protein 6	0.011
Kif3a	kinesin family member 3A	0.011
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.011
Tbx10	T-box 10	0.011
Kcnk4	potassium channel, subfamily K, member 4	0.011
Sult5a1	sulfotransferase family 5A, member 1	0.011
Hoxa7	homeobox A7	0.011
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.011
Figla	folliculogenesis specific basic helix-loop-helix	0.011
Tcap	titin-cap	0.011
Inhbb	inhibin beta-B	0.011
Socs1	suppressor of cytokine signaling 1	0.010
Scn5a	sodium channel, voltage-gated, type V, alpha	0.010
Adrb1	adrenergic receptor, beta 1	0.010
Moxd2	monooxygenase, DBH-like 2	0.010
Hoxa9	homeobox A9	0.010
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.010
Fgf2	fibroblast growth factor 2	0.010	Mouse
Tbx4	T-box 4	0.010
Dlx6	distal-less homeobox 6	0.010
Tcfap2a	transcription factor AP-2, alpha	0.010
Hhip	Hedgehog-interacting protein	0.010
Irs1	insulin receptor substrate 1	0.010
Osr1	odd-skipped related 1 (Drosophila)	0.010
Fgf17	fibroblast growth factor 17	0.010