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Process View

Mus musculus

11 genes annotated in mouse

ventral spinal cord interneuron specification

The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ventral spinal cord interneuron specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ventral spinal cord interneuron specification" (in gray)

Name	Description	Probability	Func Analog Organism
Otx2	orthodenticle homolog 2 (Drosophila)	1.000
Shh	sonic hedgehog	1.000
Gli3	GLI-Kruppel family member GLI3	1.000
Pitx2	paired-like homeodomain transcription factor 2	0.999
Pax2	paired box gene 2	0.999
Pax6	paired box gene 6	0.998
Fgf8	fibroblast growth factor 8	0.998
Pax3	paired box gene 3	0.997
Emx2	empty spiracles homolog 2 (Drosophila)	0.990
Foxc2	forkhead box C2	0.989
Tbx1	T-box 1	0.987
Foxc1	forkhead box C1	0.986
Tcfap2a	transcription factor AP-2, alpha	0.986
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.983
Sox9	SRY-box containing gene 9	0.976
Gbx2	gastrulation brain homeobox 2	0.966
Emx1	empty spiracles homolog 1 (Drosophila)	0.965
Lhx1	LIM homeobox protein 1	0.961	Mouse
Rarg	retinoic acid receptor, gamma	0.929
Isl1	ISL1 transcription factor, LIM/homeodomain	0.922	Mouse
Eya1	eyes absent 1 homolog (Drosophila)	0.913
Otx1	orthodenticle homolog 1 (Drosophila)	0.906
Sox2	SRY-box containing gene 2	0.906
Hoxd3	homeobox D3	0.894	Mouse
Msx1	homeobox, msh-like 1	0.894
Lhx3	LIM homeobox protein 3	0.883
Insm1	insulinoma-associated 1	0.859
Gli2	GLI-Kruppel family member GLI2	0.848
Foxg1	forkhead box G1	0.806
Hand2	heart and neural crest derivatives expressed transcript 2	0.777
Fgfr2	fibroblast growth factor receptor 2	0.730
Rarb	retinoic acid receptor, beta	0.715
Lmx1b	LIM homeobox transcription factor 1 beta	0.705	Mouse
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.697
Hoxb3	homeobox B3	0.669	Mouse
Lhx5	LIM homeobox protein 5	0.660	Mouse
En1	engrailed 1	0.654
Phox2b	paired-like homeobox 2b	0.647
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.647
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.622
Msx2	homeobox, msh-like 2	0.614
Hoxa1	homeobox A1	0.610
Hes5	hairy and enhancer of split 5 (Drosophila)	0.597
Dlx5	distal-less homeobox 5	0.594
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.549
Chrd	chordin	0.545
Hoxa3	homeobox A3	0.517	Mouse
Smo	smoothened homolog (Drosophila)	0.497
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.490
Sall3	sal-like 3 (Drosophila)	0.481
Nodal	nodal	0.478
Ednra	endothelin receptor type A	0.474
Fgf10	fibroblast growth factor 10	0.450
Nkx6-1	NK6 homeobox 1	0.419
Gsc	goosecoid homeobox	0.397
Wnt1	wingless-related MMTV integration site 1	0.393
Hoxd13	homeobox D13	0.377
Sox3	SRY-box containing gene 3	0.333
Hoxa2	homeobox A2	0.328
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.317
Hmx1	H6 homeobox 1	0.316
Bmp7	bone morphogenetic protein 7	0.308
Pou4f2	POU domain, class 4, transcription factor 2	0.301
Pax9	paired box gene 9	0.292
Rara	retinoic acid receptor, alpha	0.287
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.284
Pitx1	paired-like homeodomain transcription factor 1	0.273
Hoxb1	homeobox B1	0.267
Hoxd11	homeobox D11	0.256
Uncx	UNC homeobox	0.253
Nkx3-2	NK3 homeobox 2	0.245
Wnt3a	wingless-related MMTV integration site 3A	0.242
Sox11	SRY-box containing gene 11	0.239
Hand1	heart and neural crest derivatives expressed transcript 1	0.224
Chd7	chromodomain helicase DNA binding protein 7	0.223
Atoh7	atonal homolog 7 (Drosophila)	0.220
Wt1	Wilms tumor 1 homolog	0.220
Neurod1	neurogenic differentiation 1	0.210
Neurog2	neurogenin 2	0.208
Lmx1a	LIM homeobox transcription factor 1 alpha	0.191	Mouse
Foxb1	forkhead box B1	0.184
Pdx1	pancreatic and duodenal homeobox 1	0.181
Nog	noggin	0.172
Gdnf	glial cell line derived neurotrophic factor	0.171
Twist2	twist homolog 2 (Drosophila)	0.165
Bmp4	bone morphogenetic protein 4	0.162
Lhx9	LIM homeobox protein 9	0.161	Mouse
Dlx1	distal-less homeobox 1	0.159
Zic3	zinc finger protein of the cerebellum 3	0.158
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.150
Tlx3	T-cell leukemia, homeobox 3	0.149
Pax7	paired box gene 7	0.148
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.144
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.143
Zic2	zinc finger protein of the cerebellum 2	0.137
Fgf3	fibroblast growth factor 3	0.128
Tcfap2c	transcription factor AP-2, gamma	0.126
Alx4	aristaless-like homeobox 4	0.126
Igfbpl1	insulin-like growth factor binding protein-like 1	0.124
Hoxd1	homeobox D1	0.121
Pou3f4	POU domain, class 3, transcription factor 4	0.117
Sall4	sal-like 4 (Drosophila)	0.112
Fgf15	fibroblast growth factor 15	0.111
Foxh1	forkhead box H1	0.107
Pou4f3	POU domain, class 4, transcription factor 3	0.105
Evx1	even skipped homeotic gene 1 homolog	0.101
Hoxd9	homeobox D9	0.100
Hes3	hairy and enhancer of split 3 (Drosophila)	0.099
Hoxb6	homeobox B6	0.098
Hoxa4	homeobox A4	0.098
Onecut1	one cut domain, family member 1	0.094
Hoxa13	homeobox A13	0.091
Dlx2	distal-less homeobox 2	0.088
Gli1	GLI-Kruppel family member GLI1	0.086	Zebrafish Mouse
Hoxb4	homeobox B4	0.085
Gata4	GATA binding protein 4	0.080
Pou3f3	POU domain, class 3, transcription factor 3	0.076
Zfp219	zinc finger protein 219	0.073
Mesp1	mesoderm posterior 1	0.072
Hmx3	H6 homeobox 3	0.071
Ptf1a	pancreas specific transcription factor, 1a	0.068
BC024139	cDNA sequence BC024139	0.065
Ret	ret proto-oncogene	0.065
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.065
Arx	aristaless related homeobox	0.063
Prop1	paired like homeodomain factor 1	0.063
Msx3	homeobox, msh-like 3	0.061
Sox10	SRY-box containing gene 10	0.061
Pax8	paired box gene 8	0.061
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.060
Foxf1a	forkhead box F1a	0.060
Vangl2	vang-like 2 (van gogh, Drosophila)	0.060
Lef1	lymphoid enhancer binding factor 1	0.059
Neurog3	neurogenin 3	0.059
Col22a1	collagen, type XXII, alpha 1	0.058
Hoxb2	homeobox B2	0.054
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.052
En2	engrailed 2	0.051
Efna4	ephrin A4	0.051
Alx1	ALX homeobox 1	0.050
Foxb2	forkhead box B2	0.049
Fgfr1	fibroblast growth factor receptor 1	0.049
Tcf15	transcription factor 15	0.049
Hmx2	H6 homeobox 2	0.048
Pias1	protein inhibitor of activated STAT 1	0.048
Hoxa11	homeobox A11	0.048
Hoxa5	homeobox A5	0.047
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.047
Robo3	roundabout homolog 3 (Drosophila)	0.046
Ncoa3	nuclear receptor coactivator 3	0.046
Lhx6	LIM homeobox protein 6	0.045	Mouse
Atoh1	atonal homolog 1 (Drosophila)	0.044
Vax1	ventral anterior homeobox containing gene 1	0.044
Tbx3	T-box 3	0.043
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.043
Hesx1	homeobox gene expressed in ES cells	0.043
Hoxc5	homeobox C5	0.043
Foxe3	forkhead box E3	0.042
Dmbx1	diencephalon/mesencephalon homeobox 1	0.042
Col2a1	collagen, type II, alpha 1	0.041
Hoxa10	homeobox A10	0.040
Wnt6	wingless-related MMTV integration site 6	0.037
Mab21l2	mab-21-like 2 (C. elegans)	0.037
Gata3	GATA binding protein 3	0.036
T	brachyury	0.036
Col9a2	collagen, type IX, alpha 2	0.036
Wnt9b	wingless-type MMTV integration site 9B	0.036
Hoxc4	homeobox C4	0.035
Sap18	Sin3-associated polypeptide 18	0.035
Cdx1	caudal type homeobox 1	0.034
Wnt8b	wingless related MMTV integration site 8b	0.033
Setdb1	SET domain, bifurcated 1	0.033
Prrx2	paired related homeobox 2	0.033
Hoxb7	homeobox B7	0.033
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.033
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.032
Stra8	stimulated by retinoic acid gene 8	0.032
Neurog1	neurogenin 1	0.032
Sim1	single-minded homolog 1 (Drosophila)	0.032
Hoxb5	homeobox B5	0.032
Fgf17	fibroblast growth factor 17	0.032
Dlx6	distal-less homeobox 6	0.030
Sox14	SRY-box containing gene 14	0.030
Hoxd10	homeobox D10	0.029
Foxl2	forkhead box L2	0.029
Foxa2	forkhead box A2	0.029
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.028
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.027
Pou5f1	POU domain, class 5, transcription factor 1	0.027
Tbx10	T-box 10	0.027
Zeb1	zinc finger E-box binding homeobox 1	0.026
Hoxa9	homeobox A9	0.026
Lgals3	lectin, galactose binding, soluble 3	0.025
Hoxb9	homeobox B9	0.025
Zp3	zona pellucida glycoprotein 3	0.025
Phox2a	paired-like homeobox 2a	0.025
Fgf20	fibroblast growth factor 20	0.024
Zic1	zinc finger protein of the cerebellum 1	0.024
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.024
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.024
Disp1	dispatched homolog 1 (Drosophila)	0.023
Prrx1	paired related homeobox 1	0.023
Myog	myogenin	0.023
Foxd2	forkhead box D2	0.023
Irx1	Iroquois related homeobox 1 (Drosophila)	0.023
Gsx2	GS homeobox 2	0.023	Mouse
Pou3f1	POU domain, class 3, transcription factor 1	0.023
Bdnf	brain derived neurotrophic factor	0.023
Zbtb7c	zinc finger and BTB domain containing 7C	0.023
Cfc1	cripto, FRL-1, cryptic family 1	0.022
Rln1	relaxin 1	0.022
Nhlh1	nescient helix loop helix 1	0.022
Pax1	paired box gene 1	0.022
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.022
Sall1	sal-like 1 (Drosophila)	0.022
Foxd3	forkhead box D3	0.022
Ihh	Indian hedgehog	0.022
Shox2	short stature homeobox 2	0.021
Foxd1	forkhead box D1	0.020
Pou3f2	POU domain, class 3, transcription factor 2	0.020
Tcfap2b	transcription factor AP-2 beta	0.020
Ncan	neurocan	0.020
Cldn9	claudin 9	0.019
Meox2	mesenchyme homeobox 2	0.019
Olig2	oligodendrocyte transcription factor 2	0.019
Sox1	SRY-box containing gene 1	0.019
Hoxc6	homeobox C6	0.019
Pou4f1	POU domain, class 4, transcription factor 1	0.019
Dmrtb1	DMRT-like family B with proline-rich C-terminal, 1	0.019
Tbx15	T-box 15	0.019
Hoxc8	homeobox C8	0.019
Trp63	transformation related protein 63	0.019
Emid2	EMI domain containing 2	0.019
Matn3	matrilin 3	0.018
Irs4	insulin receptor substrate 4	0.018
Wnt4	wingless-related MMTV integration site 4	0.018
Hoxd4	homeobox D4	0.018
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.018
Wnt3	wingless-related MMTV integration site 3	0.018
Nkx2-1	NK2 homeobox 1	0.018
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.018
Sox4	SRY-box containing gene 4	0.018
Hes1	hairy and enhancer of split 1 (Drosophila)	0.018
Myod1	myogenic differentiation 1	0.017
Tlx2	T-cell leukemia, homeobox 2	0.017
Alx3	aristaless-like homeobox 3	0.017
Zic4	zinc finger protein of the cerebellum 4	0.017
Fam65c	family with sequence similarity 65, member C	0.017
Osr1	odd-skipped related 1 (Drosophila)	0.017
Tll2	tolloid-like 2	0.017
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.017
Nrtn	neurturin	0.017
Rax	retina and anterior neural fold homeobox	0.016
Artn	artemin	0.016
Adamts7	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7	0.016
Myf5	myogenic factor 5	0.016
5730559C18Rik	RIKEN cDNA 5730559C18 gene	0.016
Fev	FEV (ETS oncogene family)	0.016
Gipc3	GIPC PDZ domain containing family, member 3	0.016
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.016
Chrna4	cholinergic receptor, nicotinic, alpha polypeptide 4	0.016
Bnc1	basonuclin 1	0.016
Evx2	even skipped homeotic gene 2 homolog	0.016	Mouse
Sox21	SRY-box containing gene 21	0.016
Tlx1	T-cell leukemia, homeobox 1	0.016
Cldn6	claudin 6	0.015
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.015
Fgf4	fibroblast growth factor 4	0.015
Ebf3	early B-cell factor 3	0.015
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.015
Ntf3	neurotrophin 3	0.015
Hoxa7	homeobox A7	0.015
Foxi1	forkhead box I1	0.015
Dll3	delta-like 3 (Drosophila)	0.015
Accn4	amiloride-sensitive cation channel 4, pituitary	0.014
Padi3	peptidyl arginine deiminase, type III	0.014
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.014
Foxa1	forkhead box A1	0.014
Fgfr3	fibroblast growth factor receptor 3	0.014
Sim2	single-minded homolog 2 (Drosophila)	0.014
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.014
Naa11	N(alpha)-acetyltransferase 11, NatA catalytic subunit	0.014
Cnpy1	canopy 1 homolog (zebrafish)	0.013
Gpr27	G protein-coupled receptor 27	0.013
Wnt9a	wingless-type MMTV integration site 9A	0.013
Kiss1r	KISS1 receptor	0.013
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.013
Sp5	trans-acting transcription factor 5	0.013
Wbscr28	Williams-Beuren syndrome chromosome region 28 (human)	0.013
Mnx1	motor neuron and pancreas homeobox 1	0.013
Tnp2	transition protein 2	0.013
Tulp1	tubby like protein 1	0.013
Olig3	oligodendrocyte transcription factor 3	0.012
Vgll2	vestigial like 2 homolog (Drosophila)	0.012
BC051019	cDNA sequence BC051019	0.012
Wnt5b	wingless-related MMTV integration site 5B	0.012
Phlda2	pleckstrin homology-like domain, family A, member 2	0.012
2610109H07Rik	RIKEN cDNA 2610109H07 gene	0.012
Gsx1	GS homeobox 1	0.012	Mouse
Twist1	twist homolog 1 (Drosophila)	0.012
Scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.012
Barhl2	BarH-like 2 (Drosophila)	0.012
Hoxc10	homeobox C10	0.012
Dcc	deleted in colorectal carcinoma	0.012
Fzd10	frizzled homolog 10 (Drosophila)	0.012
Rassf10	Ras association (RalGDS/AF-6) domain family (N-terminal) member 10	0.012
Prph	peripherin	0.012
Oprd1	opioid receptor, delta 1	0.011
Magel2	melanoma antigen, family L, 2	0.011
Kiss1	KiSS-1 metastasis-suppressor	0.011
Tecta	tectorin alpha	0.011
Hoxd8	homeobox D8	0.011
Mab21l1	mab-21-like 1 (C. elegans)	0.011
Gja3	gap junction protein, alpha 3	0.011
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.011
Lhx4	LIM homeobox protein 4	0.011	Mouse
Foxl1	forkhead box L1	0.011
Foxn4	forkhead box N4	0.011
Mdfi	MyoD family inhibitor	0.011
Tdrd1	tudor domain containing 1	0.011
Tbx4	T-box 4	0.011
Jag1	jagged 1	0.010
Rhox6	reproductive homeobox 6	0.010
Zfp503	zinc finger protein 503	0.010
Gdf11	growth differentiation factor 11	0.010
Gbx1	gastrulation brain homeobox 1	0.010
Dmrt3	doublesex and mab-3 related transcription factor 3	0.010
Fgf9	fibroblast growth factor 9	0.010
Hoxd12	homeobox D12	0.010
Ptch2	patched homolog 2	0.010
Hhex	hematopoietically expressed homeobox	0.010