IMP

Process View

Mus musculus

3 genes annotated in mouse

Multi-species View

positive regulation of vasodilation

GO:0045909

Any process that activates or increases the frequency, rate or extent of vasodilation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of vasodilation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of vasodilation" (in gray)

Name	Description	Probability	Func Analog Organism
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.540
Nos3	nitric oxide synthase 3, endothelial cell	0.310
Kl	klotho	0.161
Bcar1	breast cancer anti-estrogen resistance 1	0.155
Agtr1a	angiotensin II receptor, type 1a	0.138
ND6	NADH dehydrogenase subunit 6	0.135
Vegfa	vascular endothelial growth factor A	0.125
Lepr	leptin receptor	0.114
Lmna	lamin A	0.099
Src	Rous sarcoma oncogene	0.094
Dmd	dystrophin, muscular dystrophy	0.083
Vdr	vitamin D receptor	0.075
Dsg4	desmoglein 4	0.073
Pparg	peroxisome proliferator activated receptor gamma	0.072
Ren1	renin 1 structural	0.072
Lep	leptin	0.069
Cav1	caveolin 1, caveolae protein	0.063
Il1rapl1	interleukin 1 receptor accessory protein-like 1	0.060
Plce1	phospholipase C, epsilon 1	0.044
Foxa2	forkhead box A2	0.044
Tlr2	toll-like receptor 2	0.039
Npy2r	neuropeptide Y receptor Y2	0.039
Cfh	complement component factor h	0.039
Phldb2	pleckstrin homology-like domain, family B, member 2	0.038
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.035
Npy1r	neuropeptide Y receptor Y1	0.035
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.033
Tjp1	tight junction protein 1	0.032
Ret	ret proto-oncogene	0.032
Timp4	tissue inhibitor of metalloproteinase 4	0.032
Rp1	retinitis pigmentosa 1 (human)	0.031
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.031
Nrp1	neuropilin 1	0.030
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.030
Reln	reelin	0.029
Fgfr2	fibroblast growth factor receptor 2	0.028
Gpr37l1	G protein-coupled receptor 37-like 1	0.027
Tyr	tyrosinase	0.027
Agtr2	angiotensin II receptor, type 2	0.026	Human
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.026
Jag1	jagged 1	0.026
Ptgs2	prostaglandin-endoperoxide synthase 2	0.025
Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	0.025
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.025
Tgfa	transforming growth factor alpha	0.024
Fyn	Fyn proto-oncogene	0.024
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.024
Cplx1	complexin 1	0.024
Bmp4	bone morphogenetic protein 4	0.023
Nos2	nitric oxide synthase 2, inducible	0.023
Meox2	mesenchyme homeobox 2	0.023
Errfi1	ERBB receptor feedback inhibitor 1	0.023
Cdh1	cadherin 1	0.023
Adora2a	adenosine A2a receptor	0.022
Ift88	intraflagellar transport 88 homolog (Chlamydomonas)	0.022
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.021
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.021
Gsdma3	gasdermin A3	0.021
Msx2	homeobox, msh-like 2	0.021
Hif1a	hypoxia inducible factor 1, alpha subunit	0.020
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.020
Fn1	fibronectin 1	0.020
Adcy2	adenylate cyclase 2	0.020
Plau	plasminogen activator, urokinase	0.019
Bdnf	brain derived neurotrophic factor	0.019
Adrb1	adrenergic receptor, beta 1	0.019
Plat	plasminogen activator, tissue	0.019
Cybb	cytochrome b-245, beta polypeptide	0.019
Supv3l1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.019
Rho	rhodopsin	0.019
Ptprn	protein tyrosine phosphatase, receptor type, N	0.019
Pcsk2	proprotein convertase subtilisin/kexin type 2	0.018
Sh3d19	SH3 domain protein D19	0.018
Flt1	FMS-like tyrosine kinase 1	0.018
Slc9a3r1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.018
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.018
Robo1	roundabout homolog 1 (Drosophila)	0.018
Myh10	myosin, heavy polypeptide 10, non-muscle	0.017
Wnk4	WNK lysine deficient protein kinase 4	0.017
Robo2	roundabout homolog 2 (Drosophila)	0.017
Slc26a3	solute carrier family 26, member 3	0.017
Ctsz	cathepsin Z	0.017
Mc4r	melanocortin 4 receptor	0.017
L1cam	L1 cell adhesion molecule	0.017
Kcnk2	potassium channel, subfamily K, member 2	0.017
Grb7	growth factor receptor bound protein 7	0.017
Prkce	protein kinase C, epsilon	0.017
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.017
Apoe	apolipoprotein E	0.016
Syn2	synapsin II	0.016
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.016
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.016
Rdh10	retinol dehydrogenase 10 (all-trans)	0.016
Ctnna1	catenin (cadherin associated protein), alpha 1	0.016
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.016
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.016
Lrrc6	leucine rich repeat containing 6 (testis)	0.016
Tgfb1	transforming growth factor, beta 1	0.015
Pkd2	polycystic kidney disease 2	0.015
Twist2	twist homolog 2 (Drosophila)	0.015
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.015
Efnb2	ephrin B2	0.015
Ocln	occludin	0.015
Npr2	natriuretic peptide receptor 2	0.015
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.015
Jph3	junctophilin 3	0.015
Prkg1	protein kinase, cGMP-dependent, type I	0.015
Pls3	plastin 3 (T-isoform)	0.015
Ptprg	protein tyrosine phosphatase, receptor type, G	0.015
Tmem79	transmembrane protein 79	0.015
Esrrg	estrogen-related receptor gamma	0.015
Csda	cold shock domain protein A	0.015
Pxn	paxillin	0.015
Gpc4	glypican 4	0.015
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.015
Lif	leukemia inhibitory factor	0.014
Gdnf	glial cell line derived neurotrophic factor	0.014
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.014
Adipoq	adiponectin, C1Q and collagen domain containing	0.014
Bmp2	bone morphogenetic protein 2	0.014
Smad1	MAD homolog 1 (Drosophila)	0.014
Meis2	Meis homeobox 2	0.014
Ptgds	prostaglandin D2 synthase (brain)	0.014
Wdr19	WD repeat domain 19	0.014
Fermt2	fermitin family homolog 2 (Drosophila)	0.014
Vtn	vitronectin	0.014
Ldlr	low density lipoprotein receptor	0.013
Lrp1	low density lipoprotein receptor-related protein 1	0.013
Dync1i1	dynein cytoplasmic 1 intermediate chain 1	0.013
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.013
Etl4	enhancer trap locus 4	0.013
Cnn3	calponin 3, acidic	0.013
Pdx1	pancreatic and duodenal homeobox 1	0.013
Acvr2b	activin receptor IIB	0.013
Slc12a1	solute carrier family 12, member 1	0.013
Aqp2	aquaporin 2	0.013
Cyp11b1	cytochrome P450, family 11, subfamily b, polypeptide 1	0.013
Adam17	a disintegrin and metallopeptidase domain 17	0.013
Icos	inducible T-cell co-stimulator	0.013
Rasgrf1	RAS protein-specific guanine nucleotide-releasing factor 1	0.013
Sos1	son of sevenless homolog 1 (Drosophila)	0.013
Ryr2	ryanodine receptor 2, cardiac	0.013
Adrb3	adrenergic receptor, beta 3	0.013
Foxc1	forkhead box C1	0.013
Yap1	yes-associated protein 1	0.013
Bglap	bone gamma carboxyglutamate protein	0.013
Agrn	agrin	0.013
Zfpm2	zinc finger protein, multitype 2	0.012
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.012
Vstm2b	V-set and transmembrane domain containing 2B	0.012
Ctsl	cathepsin L	0.012
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.012
Inhba	inhibin beta-A	0.012
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.012
Atg5	autophagy-related 5 (yeast)	0.012
Tdo2	tryptophan 2,3-dioxygenase	0.012
Klf5	Kruppel-like factor 5	0.012
Scd1	stearoyl-Coenzyme A desaturase 1	0.012
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.012
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.012
Notch2	Notch gene homolog 2 (Drosophila)	0.012
Ptgs1	prostaglandin-endoperoxide synthase 1	0.012
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.012
Adcyap1	adenylate cyclase activating polypeptide 1	0.012
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.012
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.012
Grb2	growth factor receptor bound protein 2	0.011
Adamdec1	ADAM-like, decysin 1	0.011
Nav2	neuron navigator 2	0.011
Scrg1	scrapie responsive gene 1	0.011
Armcx2	armadillo repeat containing, X-linked 2	0.011
Snai2	snail homolog 2 (Drosophila)	0.011
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.011
Cbs	cystathionine beta-synthase	0.011
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.011
Ets2	E26 avian leukemia oncogene 2, 3' domain	0.011
Socs5	suppressor of cytokine signaling 5	0.011
Pvalb	parvalbumin	0.011
Aatk	apoptosis-associated tyrosine kinase	0.011
Actl6b	actin-like 6B	0.011
Tll1	tolloid-like	0.011
Fgf1	fibroblast growth factor 1	0.011
Cadps2	Ca2+-dependent activator protein for secretion 2	0.011
En1	engrailed 1	0.011
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.011
Sctr	secretin receptor	0.011
Mas1	MAS1 oncogene	0.011
Smad7	MAD homolog 7 (Drosophila)	0.011
Grn	granulin	0.011
Sry	sex determining region of Chr Y	0.011
Clstn2	calsyntenin 2	0.011
Fgfr4	fibroblast growth factor receptor 4	0.011
Pten	phosphatase and tensin homolog	0.011
Smn1	survival motor neuron 1	0.011
Itga6	integrin alpha 6	0.011
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.011
Ptprb	protein tyrosine phosphatase, receptor type, B	0.011
Gpr35	G protein-coupled receptor 35	0.011
Chi3l1	chitinase 3-like 1	0.011
Gjb6	gap junction protein, beta 6	0.011
Atp9a	ATPase, class II, type 9A	0.011
Ugdh	UDP-glucose dehydrogenase	0.011
Lcat	lecithin cholesterol acyltransferase	0.011
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.011
Epb4.9	erythrocyte protein band 4.9	0.011
Grid2	glutamate receptor, ionotropic, delta 2	0.011
Sst	somatostatin	0.011
Grm1	glutamate receptor, metabotropic 1	0.011
Sgpl1	sphingosine phosphate lyase 1	0.011
Epb4.2	erythrocyte protein band 4.2	0.011
Colec12	collectin sub-family member 12	0.011
Kdr	kinase insert domain protein receptor	0.011
Tspan12	tetraspanin 12	0.011
Slc25a25	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25	0.011
Rit2	Ras-like without CAAX 2	0.011
Lgmn	legumain	0.011
Mt3	metallothionein 3	0.010
Odz2	odd Oz/ten-m homolog 2 (Drosophila)	0.010
Asprv1	aspartic peptidase, retroviral-like 1	0.010
Ltbp1	latent transforming growth factor beta binding protein 1	0.010
Fam84a	family with sequence similarity 84, member A	0.010
Itgb3	integrin beta 3	0.010
Spint1	serine protease inhibitor, Kunitz type 1	0.010
Chd5	chromodomain helicase DNA binding protein 5	0.010
Shank2	SH3/ankyrin domain gene 2	0.010
Cd300lf	CD300 antigen like family member F	0.010
Slc22a17	solute carrier family 22 (organic cation transporter), member 17	0.010
Plg	plasminogen	0.010
Il1f8	interleukin 1 family, member 8	0.010
Dab1	disabled homolog 1 (Drosophila)	0.010
Rgnef	Rho-guanine nucleotide exchange factor	0.010
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.010
Il1rl1	interleukin 1 receptor-like 1	0.010
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.010