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Process View

Danio rerio

18 genes annotated in zebrafish

ensheathment of neurons

The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ensheathment of neurons"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ensheathment of neurons" (in gray)

Name	Description	Probability	Func Analog Organism
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.944
sox10	SRY-box containing gene 10	0.898
notch1a	notch homolog 1a	0.580
bnc2	basonuclin 2	0.514
tuba8l3	tubulin, alpha 8 like 3	0.480
eya1	eyes absent homolog 1	0.444
six3b	sine oculis homeobox homolog 3b	0.389
cxcl12a	chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)	0.366
rx3	retinal homeobox gene 3	0.346
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.330
egr1	early growth response 1	0.321	Zebrafish
plp1a	proteolipid protein 1a	0.299
erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog	0.249
egr2b	early growth response 2b	0.240
nf1a	neurofibromin 1a	0.225	Mouse
gpm6ab	glycoprotein M6Ab	0.217	Zebrafish
gpm6ba	glycoprotein M6Ba	0.215	Zebrafish
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.206
notch3	notch homolog 3	0.178
fabp7a	fatty acid binding protein 7, brain, a	0.173
her12	hairy-related 12	0.151	Mouse
dzip1	DAZ interacting protein 1	0.146
tnc	tenascin C	0.141
mbp	myelin basic protein	0.138	Mouse
ptmaa	prothymosin, alpha a	0.134
zgc:114181	zgc:114181	0.132
gpm6aa	glycoprotein M6Aa	0.122	Zebrafish
dlc	deltaC	0.112
crb2a	crumbs homolog 2a	0.111
pou3f3b	POU class 3 homeobox 3b	0.110
gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.107
six3a	sine oculis homeobox homolog 3a	0.103
dla	deltaA	0.102
pax6a	paired box gene 6a	0.101
her15.1	hairy and enhancer of split-related 15.1	0.099	Mouse
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.098
foxa3	forkhead box A3	0.096	Zebrafish
dnmt6	DNA (cytosine-5-)-methyltransferase 6	0.089
sox19a	SRY-box containing gene 19a	0.087
neurod	neurogenic differentiation	0.083
kbp	kif1-binding protein	0.083
hs6st1a	heparan sulfate 6-O-sulfotransferase 1a	0.075
dpysl5a	dihydropyrimidinase-like 5a	0.069
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.068
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.067
pcdh10a	protocadherin 10a	0.067
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.067
cdh1	cadherin 1, epithelial	0.066
mdka	midkine-related growth factor	0.065
hmx3	homeo box (H6 family) 3	0.063
foxi3a	forkhead box I3a	0.062	Zebrafish
spry4	sprouty (Drosophila) homolog 4	0.062
dlb	deltaB	0.062
six2a	sine oculis-related homeobox 2a	0.060
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.055
eya2	eyes absent homolog 2 (Drosophila)	0.054
plp1b	proteolipid protein 1b	0.053	Zebrafish Mouse Rat
robo2	roundabout homolog 2	0.052
dnmt8	DNA (cytosine-5-)-methyltransferase 8	0.052
traf4a	tnf receptor-associated factor 4a	0.051
slc4a4b	solute carrier family 4, sodium bicarbonate cotransporter, member 4b	0.046
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.046
rx2	retinal homeobox gene 2	0.045
rtn1b	reticulon 1b	0.044
gpm6bb	glycoprotein M6Bb	0.044	Zebrafish
otx2	orthodenticle homolog 2	0.043
thrb	thyroid hormone receptor beta	0.043
hoxd3a	homeo box D3a	0.043
cldn5a	claudin 5a	0.043
mmp2	matrix metalloproteinase 2	0.043
dmrta2	doublesex and mab-3 related transcription factor like family A2	0.042
col2a1a	collagen type II, alpha-1a	0.041
fzd7b	frizzled homolog 7b	0.041
lgi1a	leucine-rich, glioma inactivated 1a	0.041
zic6	zic family member 6	0.040
rhoub	ras homolog gene family, member Ub	0.040
irx4b	iroquois homeobox protein 4b	0.040
nrarpa	notch-regulated ankyrin repeat protein a	0.039
edn1	endothelin 1	0.039
rxrga	retinoid x receptor, gamma a	0.039	Rat
rcv1	recoverin	0.039
ripk2	receptor-interacting serine-threonine kinase 2	0.038
dacha	dachshund a	0.037
olfm2	olfactomedin 2	0.037
slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.037
lfng	lunatic fringe homolog	0.036
nrg1	neuregulin 1	0.036	Rat
tuba1	tubulin, alpha 1	0.035	Zebrafish
her9	hairy-related 9	0.034
cntn1a	contactin 1a	0.034
vcanb	versican b	0.033
hs3st1l2	heparan sulfate (glucosamine) 3-O-sulfotransferase 1-like 2	0.033
nhsl1a	NHS-like 1a	0.033
prnprs3	prion protein, related sequence 3	0.033
lama2	laminin, alpha 2	0.033
lrrc4.1	leucine rich repeat containing 4.1	0.032
slc1a2b	solute carrier family 1 (glial high affinity glutamate transporter), member 2b	0.032
gnal	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	0.031
her11	hairy-related 11	0.030
vat1	vesicle amine transport protein 1 homolog (T californica)	0.030
spna2	spectrin alpha 2	0.030
prom1b	prominin 1 b	0.030
stmn1b	stathmin 1b	0.030
hnf1bb	HNF1 homeobox Bb	0.029
foxi3b	forkhead box I3b	0.029	Zebrafish
grhl2b	grainyhead-like 2b (Drosophila)	0.029
pitx3	paired-like homeodomain transcription factor 3	0.029
myod1	myogenic differentiation 1	0.028
col4a5	collagen, type IV, alpha 5 (Alport syndrome)	0.028
cntn1b	contactin 1b	0.027	Fly
zgc:77409	zgc:77409	0.027
ntrk2a	neurotrophic tyrosine kinase, receptor, type 2a	0.027
islr2	immunoglobulin superfamily containing leucine-rich repeat 2	0.027
barhl2	BarH-like 2	0.025
shha	sonic hedgehog a	0.025
mxi1	max interacting protein	0.025
foxn4	forkhead box N4	0.025
scn8aa	sodium channel, voltage-gated, type VIII, alpha a	0.025
pax6b	paired box gene 6b	0.024
pou3f1	POU class 3 homeobox 1	0.024
zgc:63523	zgc:63523	0.023
eml2	echinoderm microtubule associated protein like 2	0.023
csdc2	cold shock domain containing C2, RNA binding	0.023
ndel1a	nudE nuclear distribution gene E homolog like 1 (A. nidulans) A	0.023
slc17a6b	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b	0.023
smad3a	MAD homolog 3a (Drosophila)	0.022
plxnb2a	plexin b2a	0.022
olfm1a	olfactomedin 1a	0.022
cdh2	cadherin 2, neuronal	0.022	Rat
sox21b	SRY-box containing gene 21 b	0.022
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.021
gng13b	guanine nucleotide binding protein (G protein), gamma 13b	0.021
gnat2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.021	Fly
tnikb	TRAF2 and NCK interacting kinase b	0.021
dct	dopachrome tautomerase	0.021
robo4	roundabout homolog 4	0.021
pxn	paxillin	0.021
phox2a	paired-like homeobox 2a	0.020
raraa	retinoic acid receptor, alpha a	0.020
vcana	versican a	0.020
pknox2	pbx/knotted 1 homeobox 2	0.020
lingo1b	leucine rich repeat and Ig domain containing 1b	0.020
nort	notch-regulated transcript	0.020
zeb2a	zinc finger E-box binding homeobox 2a	0.019
foxj1a	forkhead box J1a	0.019
dlg2	discs, large (Drosophila) homolog 2	0.019
kif17	kinesin family member 17	0.019
nphs1l	nephrosis 1, congenital, Finnish type (nephrin)-like	0.019
tfe3b	transcription factor binding to IGHM enhancer 3b	0.019
pou3f2	POU class 3 homeobox 2	0.018
card14	caspase recruitment domain family, member 14	0.018
zic4	zic family member 4	0.018
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.018
zbtb4	zinc finger and BTB domain containing 4	0.018
slc4a1b	solute carrier family 4, anion exchanger, member 1b	0.018
nova2	neuro-oncological ventral antigen 2	0.018
adipor2	adiponectin receptor 2	0.018
meis2.1	myeloid ecotropic viral integration site 2.1	0.018
pou1f1	POU domain, class 1, transcription factor 1	0.017
unc5b	unc-5 homolog B (C. elegans)	0.017
tbx2b	T-box 2b	0.017
chrnb3a	cholinergic receptor, nicotinic, beta polypeptide 3a	0.017
stau1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.017
hoxb3a	homeo box B3a	0.017
flncb	filamin C, gamma b (actin binding protein 280)	0.017
zwi	zwilling	0.017
kif3b	kinesin family member 3B	0.017
gpr126	G protein-coupled receptor 126	0.017
guca1c	guanylate cyclase activator 1C	0.017
elovl4b	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4b	0.016
zgc:56466	zgc:56466	0.016
olig1	oligodendrocyte lineage transcription factor 1	0.016
ror2	receptor tyrosine kinase-like orphan receptor 2	0.016
foxd3	forkhead box D3	0.016	Zebrafish
emx3	empty spiracles homeobox 3	0.016
bhlhe22	basic helix-loop-helix family, member e22	0.016
hgfa	hepatocyte growth factor a	0.016	Rat
ntm	neurotrimin	0.016
cplx2l	complexin 2, like	0.016
cldn11a	claudin 11a	0.016
tube1	tubulin, epsilon 1	0.015
zgc:123180	zgc:123180	0.015
per2	period homolog 2 (Drosophila)	0.015
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.015
col12a1	collagen, type XII, alpha 1	0.015
emp2	epithelial membrane protein 2	0.015
si:ch211-251b21.1	si:ch211-251b21.1	0.015
etv1	ets variant gene 1	0.015
ahcy	S-adenosylhomocysteine hydrolase	0.015
gng3	guanine nucleotide binding protein (G protein), gamma 3	0.015
gpr98	G protein-coupled receptor 98	0.015
gnao1a	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a	0.015	Fly
rxrgb	retinoid X receptor, gamma b	0.015	Rat
aif1l	allograft inflammatory factor 1-like	0.015
foxj1b	forkhead box J1b	0.015
rxraa	retinoid X receptor, alpha a	0.015	Rat
pcdh19	protocadherin 19	0.015
tbr1b	T-box, brain, 1b	0.014
dram2	DNA-damage regulated autophagy modulator 2	0.014
zgc:158623	zgc:158623	0.014
cry1a	cryptochrome 1a	0.014
cetn2	centrin, EF-hand protein, 2	0.014
ca2	carbonic anhydrase II	0.014
mmp14b	matrix metalloproteinase 14b (membrane-inserted)	0.014
dmd	dystrophin	0.014
dync1h1	dynein, cytoplasmic 1, heavy chain 1	0.014
dnmt4	DNA (cytosine-5-)-methyltransferase 4	0.014
zgc:77051	zgc:77051	0.014
igf2b	insulin-like growth factor 2b	0.014
bmp2b	bone morphogenetic protein 2b	0.014
nt5e	5'-nucleotidase, ecto (CD73)	0.014
aldh2b	aldehyde dehydrogenase 2b	0.014	Zebrafish
atat1	alpha tubulin acetyltransferase 1	0.014
pde6c	phosphodiesterase 6C, cGMP-specific, cone, alpha prime	0.014
lamb1a	laminin, beta 1a	0.014
rhoua	ras homolog gene family, member Ua	0.013
lum	lumican	0.013
igsf21b	immunoglobin superfamily, member 21b	0.013
gng12a	guanine nucleotide binding protein (G protein), gamma 12a	0.013
fbxw7	F-box and WD repeat domain containing 7	0.013
sb:cb183	sb:cb183	0.013
rarga	retinoic acid receptor gamma a	0.013
ocrl	oculocerebrorenal syndrome of Lowe	0.013
guk1	guanylate kinase 1	0.013
foxg1a	forkhead box G1a	0.013	Zebrafish
add1	adducin 1 (alpha)	0.013
dcn	decorin	0.013
tmem59l	transmembrane protein 59-like and transmembrane protein 59-like	0.013
anxa5b	annexin A5b	0.013
emilin1a	elastin microfibril interfacer 1a	0.013
evpl	envoplakin	0.013
cdx4	caudal type homeo box transcription factor 4	0.013
sncb	synuclein, beta	0.013
mecom	MDS1 and EVI1 complex locus	0.013
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.013	Mouse
emx2	empty spiracles homeobox 2	0.012
grhl1	grainyhead-like 1 (Drosophila)	0.012
id4	inhibitor of DNA binding 4	0.012	Mouse
scrt1a	scratch homolog 1, zinc finger protein a (Drosophila)	0.012
LOC563527	brain-specific angiogenesis inhibitor 1-like	0.012
cx30.3	connexin 30.3	0.012
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.012
tp63	tumor protein p63	0.012
meox1	mesenchyme homeobox 1	0.012
crygm6	crystallin, gamma M6	0.012
eif3hb	eukaryotic translation initiation factor 3, subunit H, b	0.012
rbp1a	retinol binding protein 1a, cellular	0.012
tp53	tumor protein p53	0.012
kctd15a	potassium channel tetramerisation domain containing 15a	0.012
sh3gl2	SH3-domain GRB2-like 2	0.012
fezf2	FEZ family zinc finger 2	0.012
rx1	retinal homeobox gene 1	0.012
sox9a	SRY-box containing gene 9a	0.012
zgc:92116	zgc:92116	0.012
dnpep	aspartyl aminopeptidase	0.012
ext1c	exostoses (multiple) 1c	0.012
epcam	epithelial cell adhesion molecule	0.012
met	met proto-oncogene (hepatocyte growth factor receptor)	0.012
fzd7a	frizzled homolog 7a	0.012
dachb	dachshund b	0.011
elovl4a	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4a	0.011
crx	cone-rod homeobox	0.011
sfrp1b	secreted frizzled-related protein 1b	0.011
bcl2l1	bcl2-like 1	0.011
prom1a	prominin 1a	0.011
smarcd3b	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b	0.011
jam2a	junctional adhesion molecule 2a	0.011
tgfbr2	transforming growth factor, beta receptor II	0.011
foxp2	forkhead box P2	0.011
zgc:110105	zgc:110105	0.011
lrp2	low density lipoprotein-related protein 2	0.011
atp1b3b	ATPase, Na+/K+ transporting, beta 3b polypeptide	0.011
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.011
nr2f1b	nuclear receptor subfamily 2, group F, member 1b	0.011
setd7	SET domain containing (lysine methyltransferase) 7	0.011
zgc:85939	zgc:85939	0.011
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.011
rab3c	RAB3C, member RAS oncogene family	0.011
smoc1	SPARC related modular calcium binding 1	0.011
cat	catalase	0.011
tmie	transmembrane inner ear	0.011
rac3a	ras-related C3 botulinum toxin substrate 3a (rho family, small GTP binding protein Rac3)	0.011
aldh2a	aldehyde dehydrogenase 2 family (mitochondrial)a	0.011
ext1b	exostoses (multiple) 1b	0.011
wu:fa11c10	wu:fa11c10	0.011
slc1a3a	solute carrier family 1 (glial high affinity glutamate transporter), member 3a	0.011
cry2b	cryptochrome 2b	0.011
dmbx1a	diencephalon/mesencephalon homeobox 1a	0.011
neurog1	neurogenin 1	0.011
si:ch211-258f14.6	si:ch211-258f14.6	0.011
wu:fb11c03	wu:fb11c03	0.011
im:7164961	im:7164961	0.010
sec63	SEC63-like (S. cerevisiae)	0.010
aanat2	arylalkylamine N-acetyltransferase	0.010
npepps	aminopeptidase puromycin sensitive	0.010
acvr2a	activin receptor IIa	0.010
kita	kit receptor a	0.010
ythdf1	YTH domain family, member 1	0.010
nrarpb	notch-regulated ankyrin repeat protein b	0.010
usp9	ubiquitin specific peptidase 9	0.010
nrip1b	nuclear receptor interacting protein 1b	0.010
ptmab	prothymosin, alpha b	0.010
epb41l3a	erythrocyte membrane protein band 4.1-like 3a	0.010
fzd10	frizzled homolog 10	0.010