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Process View

Danio rerio

1 genes annotated in zebrafish

stem cell fate determination

The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "stem cell fate determination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "stem cell fate determination" (in gray)

Name	Description	Probability	Func Analog Organism
eng2a	engrailed 2a	0.967	Fly
pax6a	paired box gene 6a	0.849
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.734	Mouse
eng2b	engrailed 2b	0.682	Fly
nkx2.2a	NK2 transcription factor related 2a	0.664
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.587
foxn4	forkhead box N4	0.573	Fly
dla	deltaA	0.401
dlb	deltaB	0.364
vsx2	visual system homeobox 2	0.336
olig2	oligodendrocyte lineage transcription factor 2	0.231
sox3	SRY-box containing gene 3	0.197
otpb	orthopedia homolog b	0.191
neurod4	neurogenic differentiation 4	0.190
lhx1a	LIM homeobox 1a	0.185
dbx1a	developing brain homeobox 1a	0.179
dlc	deltaC	0.166
neurod	neurogenic differentiation	0.150
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.149
lhx5	LIM homeobox 5	0.149
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.144
scube2	signal peptide, CUB domain, EGF-like 2	0.143
fgf8b	fibroblast growth factor 8 b	0.138
neurog1	neurogenin 1	0.133
pou3f3b	POU class 3 homeobox 3b	0.133
prl	prolactin	0.133
sox2	SRY-box containing gene 2	0.131
gbx2	gastrulation brain homeo box 2	0.131
otx2	orthodenticle homolog 2	0.114
meis3	myeloid ecotropic viral integration site 3	0.111
ptf1a	pancreas specific transcription factor, 1a	0.107
inab	internexin neuronal intermediate filament protein, alpha b	0.097
pou3f1	POU class 3 homeobox 1	0.097
vsx1	visual system homeobox 1 homolog, chx10-like	0.095
plp1a	proteolipid protein 1a	0.090
dld	deltaD	0.088
mnx1	motor neuron and pancreas homeobox 1	0.088
ntn1a	netrin 1a	0.076
foxg1a	forkhead box G1a	0.074
gata2a	GATA-binding protein 2a	0.074
phox2a	paired-like homeobox 2a	0.072
myhz1.1	myosin, heavy polypeptide 1.1, skeletal muscle	0.070
cdh2	cadherin 2, neuronal	0.069
eya1	eyes absent homolog 1	0.068
fgfr1b	fibroblast growth factor receptor 1b	0.067
sox19a	SRY-box containing gene 19a	0.067
pou3f2	POU class 3 homeobox 2	0.065
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.065
tal1	T-cell acute lymphocytic leukemia 1	0.064
pitx3	paired-like homeodomain transcription factor 3	0.061
mbp	myelin basic protein	0.060
rad21	RAD21 homolog (S. pombe)	0.058
klf2a	Kruppel-like factor 2a	0.058
barhl2	BarH-like 2	0.056
isl1	islet1	0.053
jag1b	jagged 1b	0.049
pax3a	paired box gene 3a	0.048
gbx1	gastrulation brain homeobox 1	0.048
olig3	oligodendrocyte transcription factor 3	0.046
zic6	zic family member 6	0.043
pou1f1	POU domain, class 1, transcription factor 1	0.040
her6	hairy-related 6	0.040
cobl	cordon-bleu homolog (mouse)	0.038
irx7	iroquois homeobox protein 7	0.038
insm1b	insulinoma-associated 1b	0.038
crabp2b	cellular retinoic acid binding protein 2, b	0.037
zic4	zic family member 4	0.037
atoh7	atonal homolog 7	0.037
sox10	SRY-box containing gene 10	0.036
wnt9a	wingless-type MMTV integration site family, member 9A	0.035
pax2b	paired box gene 2b	0.033
nkx2.1b	NK2 homeobox 1b	0.032
atoh1b	atonal homolog 1b	0.032
nanos3	nanos homolog 3	0.031
pitx2	paired-like homeodomain transcription factor 2	0.030
barx1	BarH-like homeobox 1	0.030
elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.029
tp53	tumor protein p53	0.028
nkx2.2b	NK2 transcription factor related 2b	0.028
shha	sonic hedgehog a	0.028
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.027
pax2a	paired box gene 2a	0.027
meis2.2	myeloid ecotropic viral integration site 2.2	0.027
flt1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.027
six1b	sine oculis homeobox homolog 1b	0.027
irx4a	iroquois homeobox protein 4a	0.026
her4.2	hairy-related 4.2	0.026
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.026
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.025
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.025
sfrp5	secreted frizzled-related protein 5	0.025
atoh1a	atonal homolog 1a	0.025
hgfa	hepatocyte growth factor a	0.023
epha4b	eph receptor A4b	0.022
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.022
fgf8a	fibroblast growth factor 8 a	0.022
her2	hairy-related 2	0.022
cfl2l	cofilin 2, like	0.022
hoxb2a	homeo box B2a	0.022
irx1b	iroquois homeobox protein 1, b	0.021
flot1b	flotillin 1b	0.021
lrrc6	leucine rich repeat containing 6	0.021
irx3a	iroquois homeobox protein 3a	0.021
met	met proto-oncogene (hepatocyte growth factor receptor)	0.021
otx1b	orthodenticle homolog 1b	0.020
gli2a	GLI-Kruppel family member GLI2a	0.020
fzd8a	frizzled homolog 8a	0.019
myod1	myogenic differentiation 1	0.019
dcc	deleted in colorectal carcinoma	0.019
prkci	protein kinase C, iota	0.019
card14	caspase recruitment domain family, member 14	0.018
ccnd1	cyclin D1	0.018
anxa5b	annexin A5b	0.018
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.018
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.018
prdm14	PR domain containing 14	0.017
wnt11	wingless-type MMTV integration site family, member 11	0.017
ef1	ETS-related factor1	0.017
mib2	mind bomb 2	0.017
hoxa4a	homeo box A4a	0.017
mab21l2	mab-21-like 2	0.017
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.017
dab1a	disabled homolog 1a (Drosophila)	0.017
appl1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.017
LOC798783	hypothetical protein LOC798783	0.016
nes	nestin	0.016
evx1	even-skipped homeobox 1	0.016
prox1	prospero-related homeobox gene 1	0.016
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.016
pax8	paired box gene 8	0.016
lhx1b	LIM homeobox 1b	0.016
ek1	eph-like kinase 1	0.016
foxc1a	forkhead box C1a	0.016
rx1	retinal homeobox gene 1	0.015
dbx1b	developing brain homeobox 1b	0.015
cd63	Cd63 antigen	0.015
id2a	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a	0.015
pcdh18b	protocadherin 18b	0.015
lmo4a	LIM domain only 4a	0.015
hoxb1a	homeo box B1a	0.015
gfap	glial fibrillary acidic protein	0.015
cdc25	cell division cycle 25 homolog	0.015
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.014
grhl2b	grainyhead-like 2b (Drosophila)	0.014
six3a	sine oculis homeobox homolog 3a	0.014
dlx5a	distal-less homeobox gene 5a	0.014
osr2	odd-skipped related 2 (Drosophila)	0.014
tbx5a	T-box 5a	0.014
pou5f1	POU domain, class 5, transcription factor 1	0.014
jag1a	jagged 1a	0.014
dmrt3a	doublesex and mab-3 related transcription factor 3a	0.014
oc90	otoconin 90	0.013
nfe2l3	nuclear factor (erythroid-derived 2)-like 3	0.013
heyl	hairy/enhancer-of-split related with YRPW motif-like	0.013
slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.013
pcdh18a	protocadherin 18a	0.013
hhip	hedgehog interacting protein	0.012
foxn1	forkhead box N1	0.012	Fly
efnb2a	ephrin B2a	0.012
hmx3	homeo box (H6 family) 3	0.012
her9	hairy-related 9	0.012
pea3	ETS-domain transcription factor pea3	0.012
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.012
gli1	GLI-Kruppel family member 1	0.012
tfap2a	transcription factor AP-2 alpha	0.012
g2e3	G2/M-phase specific E3 ubiquitin ligase	0.012
gata3	GATA-binding protein 3	0.012
traf4a	tnf receptor-associated factor 4a	0.011
myf5	myogenic factor 5	0.011
pvrl1b	poliovirus receptor-related 1b	0.011
crybb1	crystallin, beta B1	0.011
crx	cone-rod homeobox	0.011
irx4b	iroquois homeobox protein 4b	0.011
cnn2	calponin 2	0.011
lamb2	laminin, beta 2 (laminin S)	0.011
gins3	GINS complex subunit 3	0.011
barx2	BarH-like homeobox 2	0.011
zgc:162965	zgc:162965	0.011
nod1	nucleotide-binding oligomerization domain containing 1	0.011
rx3	retinal homeobox gene 3	0.011
chrna6	cholinergic receptor, nicotinic, alpha 6	0.011
nkx2.3	NK2 transcription factor related 3	0.011
fgf22	fibroblast growth factor 22	0.011
ighm	immunoglobulin heavy constant mu and immunoglobulin heavy constant mu	0.010
ctnnd2b	catenin (cadherin-associated protein), delta 2b	0.010
thsd7a	thrombospondin, type I, domain containing 7A	0.010
sox19b	SRY-box containing gene 19b	0.010
gyltl1b	glycosyltransferase-like 1b	0.010
rx2	retinal homeobox gene 2	0.010
prdm5	PR domain containing 5	0.010
pdzrn3	PDZ domain containing RING finger 3 and PDZ domain containing ring finger 3	0.010