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Danio rerio

12 genes annotated in zebrafish

ventral spinal cord interneuron differentiation

The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ventral spinal cord interneuron differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ventral spinal cord interneuron differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
nkx2.2a	NK2 transcription factor related 2a	0.999
dla	deltaA	0.996	Zebrafish
jag1b	jagged 1b	0.984	Zebrafish
gata2a	GATA-binding protein 2a	0.971
nkx6.1	NK6 transcription factor related, locus 1 (Drosophila)	0.960	Mouse
foxa1	forkhead box A1	0.954
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.950	Mouse
olig3	oligodendrocyte transcription factor 3	0.917
nkx2.2b	NK2 transcription factor related 2b	0.916
pax2a	paired box gene 2a	0.883
dbx1a	developing brain homeobox 1a	0.877
hhex	hematopoietically expressed homeobox	0.866
foxa2	forkhead box A2	0.835
notch1a	notch homolog 1a	0.833
dlb	deltaB	0.801	Zebrafish
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.797
shha	sonic hedgehog a	0.677
isl1	islet1	0.676
tal1	T-cell acute lymphocytic leukemia 1	0.651
hand2	heart and neural crest derivatives expressed transcript 2	0.645
neurog1	neurogenin 1	0.644
otpb	orthopedia homolog b	0.635
dld	deltaD	0.586	Zebrafish
nkx2.9	NK2 transcription factor related, locus 9 (Drosophila)	0.535
olig2	oligodendrocyte lineage transcription factor 2	0.522
hoxa2b	homeo box A2b	0.486
cdx4	caudal type homeo box transcription factor 4	0.482
sox1a	SRY-box containing gene 1a	0.474
foxi1	forkhead box I1	0.429
sox10	SRY-box containing gene 10	0.336
nkx2.1a	NK2 homeobox 1a	0.334	Zebrafish
mnx1	motor neuron and pancreas homeobox 1	0.333
lhx5	LIM homeobox 5	0.332
hlxb9la	homeo box HB9 like a	0.331
drd2a	dopamine receptor D2a	0.324	Zebrafish
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.302
gja3	gap junction protein, alpha 3	0.280
eng2a	engrailed 2a	0.245
sox19a	SRY-box containing gene 19a	0.236
insm1b	insulinoma-associated 1b	0.235
gbx1	gastrulation brain homeobox 1	0.212
gata6	GATA-binding protein 6	0.210
gata3	GATA-binding protein 3	0.210
six3b	sine oculis homeobox homolog 3b	0.195
gli2a	GLI-Kruppel family member GLI2a	0.194	Zebrafish Mouse
neurod4	neurogenic differentiation 4	0.189
prl	prolactin	0.177
edn1	endothelin 1	0.174
lmo2	LIM domain only 2 (rhombotin-like 1)	0.167
zic6	zic family member 6	0.156
meis3	myeloid ecotropic viral integration site 3	0.153
rx3	retinal homeobox gene 3	0.150
neurod	neurogenic differentiation	0.145
nkx2.5	NK2 transcription factor related 5	0.145	Zebrafish
pcdh18a	protocadherin 18a	0.135
hhip	hedgehog interacting protein	0.134
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.129
pax8	paired box gene 8	0.129
pax6a	paired box gene 6a	0.129	Mouse
vsx2	visual system homeobox 2	0.127
pitx2	paired-like homeodomain transcription factor 2	0.124
disp1	dispatched homolog 1 (Drosophila)	0.124
nkx2.1b	NK2 homeobox 1b	0.123	Zebrafish
foxg1a	forkhead box G1a	0.120
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.112
eya1	eyes absent homolog 1	0.106
drd2l	dopamine receptor D2 like	0.098	Zebrafish
her3	hairy-related 3	0.097
ptf1a	pancreas specific transcription factor, 1a	0.096
pou3f3b	POU class 3 homeobox 3b	0.091
tfap2a	transcription factor AP-2 alpha	0.091
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.086
dlc	deltaC	0.085	Zebrafish
isl2a	islet2a	0.083
lhx1a	LIM homeobox 1a	0.083
pou1f1	POU domain, class 1, transcription factor 1	0.080
her8a	hairy-related 8a	0.079
pou3f3a	POU class 3 homeobox 3a	0.075
fzd8a	frizzled homolog 8a	0.070
lhx1b	LIM homeobox 1b	0.066
olig4	oligodendrocyte transcription factor 4	0.066	Zebrafish
irx4b	iroquois homeobox protein 4b	0.065
zic4	zic family member 4	0.062
met	met proto-oncogene (hepatocyte growth factor receptor)	0.061
dcc	deleted in colorectal carcinoma	0.061
eng2b	engrailed 2b	0.059
dmrt3a	doublesex and mab-3 related transcription factor 3a	0.058	Mouse
nkx6.2	NK6 transcription factor related, locus 2	0.057	Mouse
reln	reelin	0.056
hlxb9lb	homeo box HB9 like b	0.056
meis2.1	myeloid ecotropic viral integration site 2.1	0.054
fezf2	FEZ family zinc finger 2	0.051
dbx1b	developing brain homeobox 1b	0.049	Mouse
pdx1	pancreatic and duodenal homeobox 1	0.046
flh	floating head	0.046
lhx3	LIM homeobox 3	0.045
hoxa3a	homeo box A3a	0.044
irx4a	iroquois homeobox protein 4a	0.044
phox2a	paired-like homeobox 2a	0.042
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.042
irx3a	iroquois homeobox protein 3a	0.041
hoxb1a	homeo box B1a	0.041
irx1b	iroquois homeobox protein 1, b	0.041
her2	hairy-related 2	0.040
zgc:101606	zgc:101606	0.040
tbx1	T-box 1	0.039
six4b	sine oculis homeobox homolog 4b	0.038
pnx	posterior neuron-specific homeobox	0.037
gdf6a	growth differentiation factor 6a	0.037
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.036
ek1	eph-like kinase 1	0.035
zic2b	zic family member 2 (odd-paired homolog, Drosophila) b	0.034
tal2	T-cell acute lymphocytic leukemia 2	0.034
hoxb2a	homeo box B2a	0.033
atoh1a	atonal homolog 1a	0.033
hoxc4a	homeo box C4a	0.033
tfap2b	transcription factor AP-2 beta	0.032
prdm14	PR domain containing 14	0.032
hgfa	hepatocyte growth factor a	0.030
sb:cb1008	sb:cb1008	0.029
spaw	southpaw	0.029
ext2	exostoses (multiple) 2	0.029
gata4	GATA-binding protein 4	0.029	Zebrafish
ncs1a	neuronal calcium sensor 1a	0.029
unc45a	unc-45 homolog A (C. elegans)	0.027
onecutl	one cut domain, family member, like	0.027
otx2	orthodenticle homolog 2	0.026
sox3	SRY-box containing gene 3	0.026
gnrh2	gonadotropin-releasing hormone 2	0.026
barhl2	BarH-like 2	0.025
nkx2.3	NK2 transcription factor related 3	0.025	Zebrafish
tp53	tumor protein p53	0.025
hoxb5a	homeo box B5a	0.025
camkvb	CaM kinase-like vesicle-associated b	0.024
inab	internexin neuronal intermediate filament protein, alpha b	0.024
ctnnd2b	catenin (cadherin-associated protein), delta 2b	0.023
foxe3	forkhead box E3	0.023
lmo3	LIM domain only 3	0.023
npnt	nephronectin	0.023
nrxn2a	neurexin 2a	0.023
zgc:113312	zgc:113312	0.022
mib	mind bomb	0.022
foxa	forkhead box A sequence	0.021
sox4b	SRY-box containing gene 4b	0.021
hoxb8a	homeo box B8a	0.021
foxd3	forkhead box D3	0.021
atoh7	atonal homolog 7	0.021
fgf3	fibroblast growth factor 3	0.021
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.021
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.021
tcf7l1b	transcription factor 7-like 1b (T-cell specific, HMG-box)	0.020
plp1a	proteolipid protein 1a	0.020
sim2	single-minded homolog 2 (Drosophila)	0.019
irx1a	iroquois homeobox protein 1, a	0.019
rarab	retinoic acid receptor, alpha b	0.019
hoxb1b	homeo box B1b	0.018
gbx2	gastrulation brain homeo box 2	0.018
myl7	myosin, light polypeptide 7, regulatory	0.017
her4.2	hairy-related 4.2	0.017
nkx1.2la	NK1 transcription factor related 2-like,a	0.017
sfrp5	secreted frizzled-related protein 5	0.017
hoxa4a	homeo box A4a	0.017
slc5a5	solute carrier family 5 (sodium iodide symporter), member 5	0.017
nr2f6b	nuclear receptor subfamily 2, group F, member 6b	0.016
lrrn1	leucine rich repeat neuronal 1	0.016
jag2	jagged 2	0.016
barx1	BarH-like homeobox 1	0.015
sst1.1	somatostatin 1, tandem duplicate 1	0.015
pax5	paired box gene 5	0.015
lrrc50	leucine rich repeat containing 50	0.014
zgc:158603	zgc:158603	0.014
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.014
fshb	follicle stimulating hormone, beta polypeptide	0.014
sox21b	SRY-box containing gene 21 b	0.014
npb	neuropeptide B	0.014
stra6	stimulated by retinoic acid gene 6 homolog (mouse)	0.014
traf4a	tnf receptor-associated factor 4a	0.014
fam20b	family with sequence similarity 20, member B (H. sapiens)	0.014
prkci	protein kinase C, iota	0.014
irx7	iroquois homeobox protein 7	0.014
pax4	paired box 4	0.014
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.014
tbx2b	T-box 2b	0.014
rx2	retinal homeobox gene 2	0.014
ins	preproinsulin	0.013
zgc:110088	zgc:110088	0.013
cdh23	cadherin-like 23	0.013
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.013
cdh7	cadherin 7, type 2	0.013
vwf	von Willebrand factor	0.013
dzip1	DAZ interacting protein 1	0.013
zic5	zic family member 5 (odd-paired homolog, Drosophila)	0.013
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.013
fgf8a	fibroblast growth factor 8 a	0.013
hoxb5b	homeo box B5b	0.013
nlgn3b	neuroligin 3b	0.013
pou3f2	POU class 3 homeobox 2	0.012
fign	fidgetin	0.012
six6a	sine oculis-related homeobox 6a	0.012
ccm2	cerebral cavernous malformation 2	0.012
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.012
hoxc1a	homeo box C1a	0.012
jag1a	jagged 1a	0.012	Zebrafish
ihha	Indian hedgehog homolog a	0.012
cldn5a	claudin 5a	0.012
drd4-rs	dopamine receptor D4 related sequence	0.012	Zebrafish
drd3	dopamine receptor D3	0.012	Zebrafish
nkx3.2	NK3 homeobox 2	0.011
apc	adenomatosis polyposis coli	0.011
pdgfab	platelet derived growth factor alpha b	0.011
serinc5	serine incorporator 5	0.011
hmx3	homeo box (H6 family) 3	0.011
gata5	GATA-binding protein 5	0.011	Zebrafish
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.011
hesx1	homeo box (expressed in ES cells) 1	0.010
gfap	glial fibrillary acidic protein	0.010
hoxb8b	homeo box B8b	0.010
prdm1a	PR domain containing 1a, with ZNF domain	0.010
notch3	notch homolog 3	0.010
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.010