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Danio rerio

1 genes annotated in zebrafish

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negative regulation of chromatin modification

GO:1903309

Any process that stops, prevents or reduces the frequency, rate or extent of chromatin modification.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of chromatin modification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of chromatin modification" (in gray)

Name	Description	Probability	Func Analog Organism
dnmt3	DNA (cytosine-5-)-methyltransferase 3	0.126
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.118
mpx	myeloid-specific peroxidase	0.065
evx1	even-skipped homeobox 1	0.053
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.047
zgc:92664	zgc:92664	0.047
lmnb1	lamin B1	0.042
dnmt7	DNA (cytosine-5-)-methyltransferase 7	0.039	Human
pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.036
gdf6a	growth differentiation factor 6a	0.036
sephs1	selenophosphate synthetase 1	0.035
zgc:110113	zgc:110113	0.034
msxd	muscle segment homeobox D	0.034
usp1	ubiquitin specific protease 1	0.031
smc3	structural maintenance of chromosomes 3	0.029
hells	helicase, lymphoid-specific	0.029
lcp1	lymphocyte cytosolic plastin 1	0.028
chtf18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.027
ssrp1a	structure specific recognition protein 1a	0.026
her3	hairy-related 3	0.026
drl	draculin	0.025
im:7156396	im:7156396	0.025
zbtb4	zinc finger and BTB domain containing 4	0.025
gnsb	glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b	0.023
rarga	retinoic acid receptor gamma a	0.023
pspc1	paraspeckle component 1	0.022
col4a5	collagen, type IV, alpha 5 (Alport syndrome)	0.022
smc2	structural maintenance of chromosomes 2	0.022
gtf2f2a	general transcription factor IIF, polypeptide 2a	0.022
anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.021
ezh2	enhancer of zeste homolog 2 (Drosophila)	0.021
whsc1	Wolf-Hirschhorn syndrome candidate 1	0.021
efna3b	ephrin A3b	0.021
eftud2	elongation factor Tu GTP binding domain containing 2	0.020
msh2	mutS homolog 2 (E. coli)	0.020
im:7137555	im:7137555	0.020
cbx1a	chromobox homolog 1a (HP1 beta homolog Drosophila)	0.020	Fly
macf1	microtubule-actin crosslinking factor 1	0.020
rbbp6	retinoblastoma binding protein 6	0.020
huwe1	HECT, UBA and WWE domain containing 1	0.019
mef2d	myocyte enhancer factor 2d	0.019
col14a1	collagen, type XIV, alpha 1	0.019
ep300b	E1A binding protein p300 b	0.019
tra2b	transformer 2 beta homolog (Drosophila)	0.019
rif1	RAP1 interacting factor homolog (yeast)	0.018
rcor2	REST corepressor 2	0.018
esco2	establishment of cohesion 1 homolog 2	0.018
nosip	nitric oxide synthase interacting protein	0.018
btg1	B-cell translocation gene 1	0.018
akt2	v-akt murine thymoma viral oncogene homolog 2	0.018
atad5a	ATPase family, AAA domain containing 5a	0.018
zbtb16a	zinc finger and BTB domain containing 16a	0.018
ncaph	non-SMC condensin I complex, subunit H	0.017
si:ch211-198a12.6	si:ch211-198a12.6	0.017
kpnb1	karyopherin (importin) beta 1	0.017
nasp	nuclear autoantigenic sperm protein (histone-binding)	0.017
hmgn3	high mobility group nucleosomal binding domain 3	0.017
jag2	jagged 2	0.017
dnmt5	DNA (cytosine-5-)-methyltransferase 5	0.017	Human
hnrnpul1	heterogeneous nuclear ribonucleoprotein U-like 1	0.017
ncf1	neutrophil cytosolic factor 1	0.017
pias4a	protein inhibitor of activated STAT, 4a	0.017
caprin1a	cell cycle associated protein 1a	0.017
wasb	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b	0.016
unc5b	unc-5 homolog B (C. elegans)	0.016
ptpro	protein tyrosine phosphatase, receptor type, O	0.016
apex1	APEX nuclease (multifunctional DNA repair enzyme) 1	0.016
gab1	GRB2-associated binding protein 1	0.016
notch3	notch homolog 3	0.016
slu7	SLU7 splicing factor homolog (S. cerevisiae)	0.016
nrarpa	notch-regulated ankyrin repeat protein a	0.016
hp1bp3	heterochromatin protein 1, binding protein 3	0.016
ash2l	ash2 (absent, small, or homeotic)-like (Drosophila)	0.016
epb4.1l4	erythrocyte protein band 4.1-like 4	0.015
cask	calcium/calmodulin-dependent serine protein kinase	0.015
ctbp1	C-terminal binding protein 1	0.015
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.015
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.015
vasp	vasodilator-stimulated phosphoprotein	0.014
ube2i2	ubiquitin-conjugating enzyme E2I2	0.014
prim1	primase polypeptide 1	0.014
fzd9b	frizzled homolog 9b	0.014
sp4	sp4 transcription factor	0.014
smc4	structural maintenance of chromosomes 4	0.014
zgc:56148	zgc:56148	0.014
wdr82	WD repeat domain containing 82	0.014
her2	hairy-related 2	0.014
strada	ste20-related kinase adaptor alpha	0.014
dnmt1	DNA (cytosine-5-)-methyltransferase 1	0.014	Human
tyms	thymidylate synthase	0.014
nrp1a	neuropilin 1a	0.014
ilf3a	interleukin enhancer binding factor 3a	0.014
zgc:103697	zgc:103697	0.014
hmg20b	high-mobility group 20B	0.014
zgc:110682	zgc:110682	0.014
mab21l2	mab-21-like 2	0.014
fam50a	family with sequence similarity 50, member A	0.014
msh6	mutS homolog 6 (E. coli)	0.014
zgc:64051	zgc:64051	0.014
gmfb	glia maturation factor, beta	0.014
id:ibd5051	id:ibd5051	0.013
ythdf1	YTH domain family, member 1	0.013
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.013
thoc2	THO complex 2	0.013
rltpr	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	0.013
pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.013
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.013
pcna	proliferating cell nuclear antigen	0.013
cand1	cullin-associated and neddylation-dissociated 1	0.013
cd99l2	CD99 antigen-like 2	0.013
mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.013
illr3	immune-related, lectin-like receptor 3	0.013
kbtbd8	kelch repeat and BTB (POZ) domain containing 8	0.013
frem1a	Fras1 related extracellular matrix 1a	0.013
smek2	SMEK homolog 2, suppressor of mek1 (Dictyostelium)	0.013
arpp19a	cAMP-regulated phosphoprotein 19a	0.013
rap1a	RAP1A, member of RAS oncogene family	0.013
wu:fc85c01	wu:fc85c01	0.013
mcm3	MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)	0.013
si:dkey-250d21.1	si:dkey-250d21.1	0.013
ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.013
hoxa13b	homeo box A13b	0.013
gata1a	GATA binding protein 1a	0.013
usf1	upstream transcription factor 1	0.012
otx1b	orthodenticle homolog 1b	0.012
ephb4b	eph receptor B4b	0.012
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.012
mcm7	MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)	0.012
cad	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.012
prickle2	prickle-like 2 (Drosophila)	0.012
sumo3a	SMT3 suppressor of mif two 3 homolog 3a	0.012
insra	insulin receptor a	0.012
smc1al	structural maintenance of chromosomes 1A, like	0.012
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.012
smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.012
nucks1a	nuclear casein kinase and cyclin-dependent kinase substrate 1a	0.012
trim71	tripartite motif-containing 71	0.012
rab11fip4a	RAB11 family interacting protein 4 (class II) a	0.012
skia	nuclear oncoprotein skia	0.012	Mouse
LOC567638	hypothetical LOC567638	0.012
nova2	neuro-oncological ventral antigen 2	0.012
zgc:92217	zgc:92217	0.012
srsf1b	serine/arginine-rich splicing factor 1b	0.012
sox19a	SRY-box containing gene 19a	0.012
dnmt8	DNA (cytosine-5-)-methyltransferase 8	0.012
lbr	lamin B receptor	0.012
irx4b	iroquois homeobox protein 4b	0.012
otx1a	orthodenticle homolog 1a	0.012
snx12	sorting nexin 12	0.011
ahctf1	AT hook containing transcription factor 1	0.011
LOC100536021	spectrin beta chain, brain 1-like	0.011
strn3	striatin, calmodulin binding protein 3	0.011
hirip3	HIRA interacting protein 3	0.011
h2afvl	H2A histone family, member V, like	0.011
pdcd11	programmed cell death 11	0.011
marcksb	myristoylated alanine rich protein kinase C substrate b	0.011
zgc:92683	zgc:92683	0.011
adam23a	a disintegrin and metallopeptidase domain 23a	0.011
zgc:91844	zgc:91844	0.011
zic6	zic family member 6	0.011
rassf8b	Ras association (RalGDS/AF-6) domain family 8b	0.011
usp7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.011
hrh1	histamine receptor H1	0.011
ctsc	cathepsin C	0.011
spred1	sprouty-related, EVH1 domain containing 1	0.011
si:ch211-278b8.3	si:ch211-278b8.3	0.011
ckap5	cytoskeleton associated protein 5	0.011
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.011
plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	0.011
zgpat	zinc finger, CCCH-type with G patch domain	0.011
cuedc2	CUE domain containing 2	0.011
zgc:154068	zgc:154068	0.011
zc3h14	zinc finger CCCH-type containing 14	0.011
tcea1	transcription elongation factor A (SII), 1	0.011
cabin1	calcineurin binding protein 1	0.011
hibadha	3-hydroxyisobutyrate dehydrogenase a	0.011
ptprc	protein tyrosine phosphatase, receptor type, C	0.011
lrrc33	leucine rich repeat containing 33	0.011
ap1s2	adaptor-related protein complex 1, sigma 2 subunit	0.011
npm4	nucleophosmin/nucleoplasmin, 4	0.011
cstf3	cleavage stimulation factor, 3' pre-RNA, subunit 3	0.011
hug	HuG	0.011
serinc5	serine incorporator 5	0.011
foxb1.1	forkhead box B1.1	0.011
pax2b	paired box gene 2b	0.011
api5	apoptosis inhibitor 5	0.011
plagx	pleiomorphic adenoma gene X	0.011
tia1	cytotoxic granule-associated RNA binding protein 1	0.011
arglu1b	arginine and glutamate rich 1b	0.011
chst10	carbohydrate sulfotransferase 10	0.011
st13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.010
rtf1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.010
jag1a	jagged 1a	0.010
pdgfab	platelet derived growth factor alpha b	0.010
zgc:103440	zgc:103440	0.010
mynn	myoneurin	0.010
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.010
zgc:153061	zgc:153061	0.010
wrb	tryptophan rich basic protein	0.010
zgc:77165	zgc:77165	0.010
fli1b	friend leukemia integration 1b	0.010
zgc:101841	zgc:101841	0.010
srrm1	serine/arginine repetitive matrix 1	0.010
syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)	0.010
zc4h2	zinc finger, C4H2 domain containing	0.010
si:ch211-57k11.10	si:ch211-57k11.10	0.010
vwf	von Willebrand factor	0.010
zdhhc8b	zinc finger, DHHC-type containing 8b	0.010
morf4l1	mortality factor 4 like 1	0.010
mbd3b	methyl-CpG binding domain protein 3b	0.010
upf1	upf1 regulator of nonsense transcripts homolog (yeast)	0.010
zeb2a	zinc finger E-box binding homeobox 2a	0.010
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.010
sb:cb911	sb:cb911	0.010
senp3a	SUMO1/sentrin/SMT3 specific peptidase 3a	0.010
si:ch211-207m11.1	si:ch211-207m11.1	0.010
zgc:101598	zgc:101598	0.010
prdm2b	PR domain containing 2, with ZNF domain b	0.010