The network for 'reproduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

reproduction

The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.

Homo sapiens
Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.981
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.929
RB1 retinoblastoma 1 0.778
QKI quaking homolog, KH domain RNA binding (mouse) 0.765
CDK2 cyclin-dependent kinase 2 0.750
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.739
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.695
CSNK2B casein kinase 2, beta polypeptide 0.689
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.688
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.584
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.579
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.579
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.565
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.527
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.511
SP1 Sp1 transcription factor 0.492
TP53 tumor protein p53 0.473
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.459
BRCA1 breast cancer 1, early onset 0.405
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.394
EP300 E1A binding protein p300 0.389
CAND1 cullin-associated and neddylation-dissociated 1 0.377
ATXN1 ataxin 1 0.369
MAPK14 mitogen-activated protein kinase 14 0.368
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.357
RNPS1 RNA binding protein S1, serine-rich domain 0.353
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.352
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.336
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.332
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.319
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.318
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.312
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.306
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.300
CREBBP CREB binding protein 0.299
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.296
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.293
SRSF2 serine/arginine-rich splicing factor 2 0.292
SNW1 SNW domain containing 1 0.292
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.279
TARDBP TAR DNA binding protein 0.272
JUN jun proto-oncogene 0.258
ATF2 activating transcription factor 2 0.254
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.250
PRPF4 PRP4 pre-mRNA processing factor 4 homolog (yeast) 0.245
TCP1 t-complex 1 0.243
ILF3 interleukin enhancer binding factor 3, 90kDa 0.240
ESR1 estrogen receptor 1 0.239
EIF3A eukaryotic translation initiation factor 3, subunit A 0.235
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 0.235
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.232
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.230
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.225
EBNA1BP2 EBNA1 binding protein 2 0.213
NCOA3 nuclear receptor coactivator 3 0.212
RUVBL2 RuvB-like 2 (E. coli) 0.209
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 0.208
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.206
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.201
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.198
RFC4 replication factor C (activator 1) 4, 37kDa 0.198
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.196
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.196
RAD21 RAD21 homolog (S. pombe) 0.193
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.193
FOS FBJ murine osteosarcoma viral oncogene homolog 0.193
CUL1 cullin 1 0.192
MCM7 minichromosome maintenance complex component 7 0.189
EIF3B eukaryotic translation initiation factor 3, subunit B 0.183
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.182
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.181
EGFR epidermal growth factor receptor 0.180
CCNB1 cyclin B1 0.178
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 0.177
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.177
TRA2B transformer 2 beta homolog (Drosophila) 0.175
RAN RAN, member RAS oncogene family 0.174
CBX5 chromobox homolog 5 0.169
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.168
SRPK2 SRSF protein kinase 2 0.157
UBC ubiquitin C 0.153
EIF4A1 eukaryotic translation initiation factor 4A1 0.152
SRPK1 SRSF protein kinase 1 0.152
CCNA2 cyclin A2 0.152
XIAP X-linked inhibitor of apoptosis 0.151
KARS lysyl-tRNA synthetase 0.151
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.150
MATR3 matrin 3 0.149
PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) 0.148
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.147
EIF4A3 eukaryotic translation initiation factor 4A3 0.147
MCM4 minichromosome maintenance complex component 4 0.145
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.142
RPL21 ribosomal protein L21 0.142
MCM3 minichromosome maintenance complex component 3 0.140
SFPQ splicing factor proline/glutamine-rich 0.139
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.139
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.138
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.137
NME1 non-metastatic cells 1, protein (NM23A) expressed in 0.136
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
piwil1 piwi-like 1 (Drosophila) 0.913
rpl19 ribosomal protein L19 0.843
bmp2b bone morphogenetic protein 2b 0.785
cyp11a1 cytochrome P450, subfamily XIA, polypeptide 1 0.778
neo1 neogenin 1 0.770
pkd2 polycystic kidney disease 2 0.769
tcp1 t-complex polypeptide 1 0.744
met met proto-oncogene (hepatocyte growth factor receptor) 0.737
nop58 NOP58 ribonucleoprotein homolog (yeast) 0.732
gro1 groucho 1 0.729
nanos3 nanos homolog 3 0.714
tp53 tumor protein p53 0.709
rps3a ribosomal protein S3A 0.707
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.666
notch3 notch homolog 3 0.642
notch1a notch homolog 1a 0.635
cct7 chaperonin containing TCP1, subunit 7 (eta) 0.612
tfap2a transcription factor AP-2 alpha 0.586
rps15a ribosomal protein S15a 0.577
mib mind bomb 0.567
cct5 chaperonin containing TCP1, subunit 5 (epsilon) 0.556
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.543
snrpc small nuclear ribonucleoprotein polypeptide C 0.538
psmb3 proteasome (prosome, macropain) subunit, beta type, 3 0.530
top2a topoisomerase (DNA) II alpha 0.503
hspa5 heat shock protein 5 0.480
fgfr1a fibroblast growth factor receptor 1a 0.479
rps18 ribosomal protein S18 0.478
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.472
rpl7 ribosomal protein L7 0.459
pabpc1a poly A binding protein, cytoplasmic 1 a 0.456
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.451
gpr126 G protein-coupled receptor 126 0.451
plcg1 phospholipase C, gamma 1 0.431
rps8a ribosomal protein S8a 0.430
sema3aa semaphorin 3aa 0.427
psmb4 proteasome (prosome, macropain) subunit, beta type, 4 0.423
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.422
bmp4 bone morphogenetic protein 4 0.419
bmp2a bone morphogenetic protein 2a 0.416
alcamb activated leukocyte cell adhesion molecule b 0.392
gli1 GLI-Kruppel family member 1 0.392
fbl fibrillarin 0.389
rpl28 ribosomal protein L28 0.379
lhx1a LIM homeobox 1a 0.368
gdf6a growth differentiation factor 6a 0.365
ruvbl2 RuvB-like 2 (E. coli) 0.363
hsp90a.1 heat shock protein 90-alpha 1 0.360
pax2a paired box gene 2a 0.355
rpl35 ribosomal protein L35 0.355
rpsa ribosomal protein SA 0.355
wnt11r wingless-type MMTV integration site family, member 11, related 0.354
smo smoothened homolog (Drosophila) 0.352
atp1a1a.4 ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide 0.352
dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) 0.349
rps11 ribosomal protein S11 0.347
rpl12 ribosomal protein L12 0.347
eif3d eukaryotic translation initiation factor 3, subunit D 0.346
rpl36a ribosomal protein L36A 0.339
rps29 ribosomal protein S29 0.339
crabp2a cellular retinoic acid binding protein 2, a 0.334
egr1 early growth response 1 0.319
pbx4 pre-B-cell leukemia transcription factor 4 0.314
rps7 ribosomal protein S7 0.309
tpbgl trophoblast glycoprotein-like 0.309
mef2ca myocyte enhancer factor 2ca 0.307
ilk integrin linked kinase 0.307
eif3g eukaryotic translation initiation factor 3, subunit G 0.305
zmat2 zinc finger, matrin type 2 0.304
six4b sine oculis homeobox homolog 4b 0.298
per3 period homolog 3 (Drosophila) 0.290
mef2d myocyte enhancer factor 2d 0.284
rpl7l1 ribosomal protein L7-like 1 0.282
pou5f1 POU domain, class 5, transcription factor 1 0.282
got2b glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2) 0.274
sf3b14 splicing factor 3B 0.274
ptpn11a protein tyrosine phosphatase, non-receptor type 11, a 0.273
rpl6 ribosomal protein L6 0.269
aurkb aurora kinase B 0.266
eif3c eukaryotic translation initiation factor 3, subunit C 0.252
khdrbs1b KH domain containing, RNA binding, signal transduction associated 1b 0.251
ptgs2a prostaglandin-endoperoxide synthase 2a 0.250
pes pescadillo 0.239
hhip hedgehog interacting protein 0.237
gata3 GATA-binding protein 3 0.237
rpl21 ribosomal protein L21 0.235
mef2a myocyte enhancer factor 2a 0.234
fancl Fanconi anemia, complementation group L 0.231
psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.228
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.227
rbb4 retinoblastoma binding protein 4 0.226
pax7a paired box gene 7a 0.225
slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.225
rps12 ribosomal protein S12 0.224
ptch2 patched 2 0.223
snai1b snail homolog 1b (Drosophila) 0.221
ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform 0.219
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.218
cct6a chaperonin containing TCP1, subunit 6A (zeta 1) 0.217
hn1l hematological and neurological expressed 1-like 0.214
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Hcrtr1 hypocretin (orexin) receptor 1 0.540
Pfn1 profilin 1 0.514
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.440
Ptprh protein tyrosine phosphatase, receptor type, H 0.386
Nefl neurofilament, light polypeptide 0.380
Cd44 Cd44 molecule 0.346
Olr1493 olfactory receptor gene Olr1493 0.331
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.323
Gip gastric inhibitory polypeptide 0.305
Prl prolactin 0.295
Mapk3 mitogen activated protein kinase 3 0.293
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.292
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.286
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.281
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.280
Fgf2 fibroblast growth factor 2 0.280
Ptafr platelet-activating factor receptor 0.273
Trhr2 thyrotropin releasing hormone receptor 2 0.262
Gad2 glutamate decarboxylase 2 0.261
Hspd1 heat shock protein 1 (chaperonin) 0.260
Ugt2b7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.260
Sstr1 somatostatin receptor 1 0.260
Scnn1g sodium channel, nonvoltage-gated 1, gamma 0.260
Ptgs2 prostaglandin-endoperoxide synthase 2 0.259
Tpm4 tropomyosin 4 0.258
Pip prolactin induced protein 0.257
Fth1 ferritin, heavy polypeptide 1 0.255
Mak male germ cell-associated kinase 0.255
Cga glycoprotein hormones, alpha polypeptide 0.250
Tpm3 tropomyosin 3, gamma 0.248
Ednrb endothelin receptor type B 0.245
Fgfr2 fibroblast growth factor receptor 2 0.242
Aqp9 aquaporin 9 0.238
Pde1c phosphodiesterase 1C 0.237
Lepr leptin receptor 0.236
Msn moesin 0.234
Apba1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.231
Fat2 FAT tumor suppressor homolog 2 (Drosophila) 0.230
Trhr thyrotropin releasing hormone receptor 0.229
Lalba lactalbumin, alpha 0.226
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.224
Myh9 myosin, heavy chain 9, non-muscle 0.223
Cnbp CCHC-type zinc finger, nucleic acid binding protein 0.223
Bbx bobby sox homolog (Drosophila) 0.222
Snap25 synaptosomal-associated protein 25 0.220
Acvr1c activin A receptor, type IC 0.220
Atp12a ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.220
Pth parathyroid hormone 0.219
Tas2r118 taste receptor, type 2, member 118 0.216
Tmpo thymopoietin 0.213
Prl8a7 prolactin family 8, subfamily a, member 7 0.212
Cand1 cullin-associated and neddylation-dissociated 1 0.211
Flt1 FMS-related tyrosine kinase 1 0.210
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.210
Anxa2 annexin A2 0.208
Syt4 synaptotagmin IV 0.206
Caprin1 cell cycle associated protein 1 0.203
Homer3 homer homolog 3 (Drosophila) 0.201
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.199
Olr857 olfactory receptor 857 0.198
Nfib nuclear factor I/B 0.197
Cxcl2 chemokine (C-X-C motif) ligand 2 0.196
Nfia nuclear factor I/A 0.195
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.195
Arf1 ADP-ribosylation factor 1 0.194
Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 0.189
Snap91 synaptosomal-associated protein 91 0.188
Pspn persephin 0.187
Lhb luteinizing hormone beta 0.185
Rap1b RAP1B, member of RAS oncogene family 0.185
Thoc2 THO complex 2 0.184
Chrna2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 0.183
Cacnb4 calcium channel, voltage-dependent, beta 4 subunit 0.183
Capza3 capping protein (actin filament) muscle Z-line, alpha 3 0.182
Kcnh1 potassium voltage-gated channel, subfamily H (eag-related), member 1 0.182
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.181
Cltc clathrin, heavy chain (Hc) 0.180
Il8rb interleukin 8 receptor, beta 0.180
Adarb2 adenosine deaminase, RNA-specific, B2 0.180
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.178
Pebp1 phosphatidylethanolamine binding protein 1 0.177
Tacr1 tachykinin receptor 1 0.175
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.175
Aqp2 aquaporin 2 (collecting duct) 0.174
Bmpr1a bone morphogenetic protein receptor, type IA 0.173
Ptgfr prostaglandin F receptor 0.172
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.171
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.171
Testin testin gene 0.171
Ifitm3 interferon induced transmembrane protein 3 0.171
Avpr2 arginine vasopressin receptor 2 0.170
Eef2 eukaryotic translation elongation factor 2 0.169
Odf1 outer dense fiber of sperm tails 1 0.169
Jak2 Janus kinase 2 0.168
Prlhr prolactin releasing hormone receptor 0.168
Kalrn kalirin, RhoGEF kinase 0.168
Cryba1 crystallin, beta A1 0.168
Nab1 Ngfi-A binding protein 1 0.166
Gjb3 gap junction protein, beta 3 0.165
Egr1 early growth response 1 0.165
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism