IMP
Process View
The network for 'positive regulation of superoxide anion generation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of superoxide anion generation
Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| IL8 | interleukin 8 | 0.947 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.847 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.828 | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.705 | |
| PRDX1 | peroxiredoxin 1 | 0.598 | |
| IL1B | interleukin 1, beta | 0.446 | |
| NOXA1 | NADPH oxidase activator 1 | 0.356 | |
| PRKCZ | protein kinase C, zeta | 0.344 | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.313 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.287 | |
| NCF1 | neutrophil cytosolic factor 1 | 0.284 | |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.239 | |
| ENG | endoglin | 0.173 | |
| PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.149 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.146 | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.144 | |
| NUMB | numb homolog (Drosophila) | 0.143 | |
| PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.137 | |
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.119 | |
| ZNF71 | zinc finger protein 71 | 0.115 | |
| CDCP1 | CUB domain containing protein 1 | 0.110 | |
| DCTN1 | dynactin 1 | 0.087 | |
| CCDC115 | coiled-coil domain containing 115 | 0.086 | |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.085 | |
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.074 | |
| CARD11 | caspase recruitment domain family, member 11 | 0.071 | |
| PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.066 | |
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.059 | |
| IER3 | immediate early response 3 | 0.056 | |
| RARA | retinoic acid receptor, alpha | 0.053 | |
| PRKCB | protein kinase C, beta | 0.052 | |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.051 | |
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 | 0.050 | |
| PICK1 | protein interacting with PRKCA 1 | 0.047 | |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.046 | |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.046 | |
| MAPT | microtubule-associated protein tau | 0.044 | |
| CYBA | cytochrome b-245, alpha polypeptide | 0.041 | |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.040 | |
| TGFB3 | transforming growth factor, beta 3 | 0.039 | |
| PARK7 | Parkinson disease (autosomal recessive, early onset) 7 | 0.037 | |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.037 | |
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.035 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.034 | |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.033 | |
| APP | amyloid beta (A4) precursor protein | 0.032 | |
| NMT2 | N-myristoyltransferase 2 | 0.029 | |
| ARRB1 | arrestin, beta 1 | 0.028 | |
| TSC22D1 | TSC22 domain family, member 1 | 0.028 | |
| THBS1 | thrombospondin 1 | 0.028 | |
| TRIM9 | tripartite motif containing 9 | 0.027 | |
| ASXL1 | additional sex combs like 1 (Drosophila) | 0.027 | |
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.027 | |
| PLAUR | plasminogen activator, urokinase receptor | 0.026 | |
| CD2 | CD2 molecule | 0.025 | |
| BCL10 | B-cell CLL/lymphoma 10 | 0.024 | |
| LCK | lymphocyte-specific protein tyrosine kinase | 0.024 | |
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.024 | |
| STK4 | serine/threonine kinase 4 | 0.024 | |
| INADL | InaD-like (Drosophila) | 0.024 | |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.024 | |
| BAD | BCL2-associated agonist of cell death | 0.024 | |
| VHL | von Hippel-Lindau tumor suppressor | 0.023 | |
| CCL14 | chemokine (C-C motif) ligand 14 | 0.023 | |
| PTEN | phosphatase and tensin homolog | 0.022 | |
| ACTB | actin, beta | 0.021 | |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.021 | |
| MBD1 | methyl-CpG binding domain protein 1 | 0.021 | |
| SQSTM1 | sequestosome 1 | 0.020 | |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.019 | |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.019 | |
| GFAP | glial fibrillary acidic protein | 0.019 | |
| COX6C | cytochrome c oxidase subunit VIc | 0.019 | |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.019 | |
| PRKCA | protein kinase C, alpha | 0.018 | |
| PEBP4 | phosphatidylethanolamine-binding protein 4 | 0.018 | |
| SMG1 | SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) | 0.018 | |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.018 | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.018 | |
| CCHCR1 | coiled-coil alpha-helical rod protein 1 | 0.018 | |
| LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.016 | |
| PRDX6 | peroxiredoxin 6 | 0.016 | |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.016 | |
| FAM129A | family with sequence similarity 129, member A | 0.016 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.015 | |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.015 | |
| THEM4 | thioesterase superfamily member 4 | 0.015 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.015 | |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.015 | |
| LRRK2 | leucine-rich repeat kinase 2 | 0.015 | |
| SH2D1A | SH2 domain containing 1A | 0.014 | |
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.014 | |
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.014 | |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 0.014 | |
| PPP1R10 | protein phosphatase 1, regulatory (inhibitor) subunit 10 | 0.014 | |
| INHBA | inhibin, beta A | 0.014 | |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.014 | |
| FYN | FYN oncogene related to SRC, FGR, YES | 0.014 | |
| MAP1LC3A | microtubule-associated protein 1 light chain 3 alpha | 0.014 | |
| MED25 | mediator complex subunit 25 | 0.014 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Lepr | leptin receptor | 0.069 | |
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.062 | |
| Ren1 | renin 1 structural | 0.030 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.018 | |
| Il1rn | interleukin 1 receptor antagonist | 0.014 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.013 | |
| Apoe | apolipoprotein E | 0.013 | |
| Vdr | vitamin D receptor | 0.012 | |
| Vegfa | vascular endothelial growth factor A | 0.011 | |
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.010 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.010 | |
| Trp53 | transformation related protein 53 | 0.010 |