The network for 'positive regulation of hormone biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of hormone biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.

Name Description Probability Func Analog Organism
EPAS1 endothelial PAS domain protein 1 1.000
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.000
EGLN1 egl nine homolog 1 (C. elegans) 0.999
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.999
AHR aryl hydrocarbon receptor 0.997
VHL von Hippel-Lindau tumor suppressor 0.993
CSH2 chorionic somatomammotropin hormone 2 0.992
ARNT aryl hydrocarbon receptor nuclear translocator 0.989
EGLN3 egl nine homolog 3 (C. elegans) 0.986
GH1 growth hormone 1 0.980
CLOCK clock homolog (mouse) 0.962
BMPR1B bone morphogenetic protein receptor, type IB 0.916
ITGB1BP3 integrin beta 1 binding protein 3 0.896
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.872
CSHL1 chorionic somatomammotropin hormone-like 1 0.847
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.835
GH2 growth hormone 2 0.718
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.713
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.625
MYO6 myosin VI 0.585
KAT2B K(lysine) acetyltransferase 2B 0.490
RB1 retinoblastoma 1 0.480
HDAC1 histone deacetylase 1 0.457
SSX4 synovial sarcoma, X breakpoint 4 0.433
FAF1 Fas (TNFRSF6) associated factor 1 0.415
NOG noggin 0.404
FGF18 fibroblast growth factor 18 0.399
MTA3 metastasis associated 1 family, member 3 0.395
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.367
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.346
PRMT6 protein arginine methyltransferase 6 0.343
MTA1 metastasis associated 1 0.338
MMP11 matrix metallopeptidase 11 (stromelysin 3) 0.325
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 0.291
INSR insulin receptor 0.289
SMAD3 SMAD family member 3 0.278
WNT1 wingless-type MMTV integration site family, member 1 0.274
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 0.258
IHH Indian hedgehog 0.258
FGF4 fibroblast growth factor 4 0.248
ESR1 estrogen receptor 1 0.232
BMP4 bone morphogenetic protein 4 0.223
IRS1 insulin receptor substrate 1 0.222
WIF1 WNT inhibitory factor 1 0.221
SOX21 SRY (sex determining region Y)-box 21 0.204
FGF8 fibroblast growth factor 8 (androgen-induced) 0.197
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.193
DLX4 distal-less homeobox 4 0.171
HES2 hairy and enhancer of split 2 (Drosophila) 0.169
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 0.157
SAMD3 sterile alpha motif domain containing 3 0.156
RCOR1 REST corepressor 1 0.156
FOXD3 forkhead box D3 0.132
CSK c-src tyrosine kinase 0.132
SREBF2 sterol regulatory element binding transcription factor 2 0.124
TG thyroglobulin 0.122
AQP5 aquaporin 5 0.121
ASCC2 activating signal cointegrator 1 complex subunit 2 0.116
GHR growth hormone receptor 0.112
PGRMC1 progesterone receptor membrane component 1 0.109
LOXL4 lysyl oxidase-like 4 0.103
LRP6 low density lipoprotein receptor-related protein 6 0.101
FRS2 fibroblast growth factor receptor substrate 2 0.097
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.097
GAB1 GRB2-associated binding protein 1 0.095
ELL elongation factor RNA polymerase II 0.095
OFCC1 orofacial cleft 1 candidate 1 0.094
COL2A1 collagen, type II, alpha 1 0.093
AR androgen receptor 0.093
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) 0.092
BARX1 BARX homeobox 1 0.092
HOXB1 homeobox B1 0.089
ADRA1D adrenergic, alpha-1D-, receptor 0.089
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.088
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.087
NPAS2 neuronal PAS domain protein 2 0.086
SP1 Sp1 transcription factor 0.083
ALX4 ALX homeobox 4 0.082
SOX1 SRY (sex determining region Y)-box 1 0.078
TACR1 tachykinin receptor 1 0.077
SCRT1 scratch homolog 1, zinc finger protein (Drosophila) 0.077
PAX3 paired box 3 0.076
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 0.075
P2RX2 purinergic receptor P2X, ligand-gated ion channel, 2 0.074
PAX7 paired box 7 0.074
NCOA7 nuclear receptor coactivator 7 0.073
WNT10A wingless-type MMTV integration site family, member 10A 0.073
GRIK3 glutamate receptor, ionotropic, kainate 3 0.072
HCRTR1 hypocretin (orexin) receptor 1 0.072
CCDC48 coiled-coil domain containing 48 0.072
GDNF glial cell derived neurotrophic factor 0.072
NCOA6 nuclear receptor coactivator 6 0.071
TBX5 T-box 5 0.068
EGFR epidermal growth factor receptor 0.066
KCNQ2 potassium voltage-gated channel, KQT-like subfamily, member 2 0.065
SNAI1 snail homolog 1 (Drosophila) 0.064
GLI1 GLI family zinc finger 1 0.064
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 0.063
HOXC8 homeobox C8 0.063
SLC6A2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 0.061
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ghr growth hormone receptor 0.886
Grb10 growth factor receptor bound protein 10 0.348
Esr1 estrogen receptor 1 (alpha) 0.221
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.190
Igf2r insulin-like growth factor 2 receptor 0.153
Lepr leptin receptor 0.086
Ahr aryl-hydrocarbon receptor 0.053
Insr insulin receptor 0.042
Ar androgen receptor 0.039
Fgfr1 fibroblast growth factor receptor 1 0.036
Vhl von Hippel-Lindau tumor suppressor 0.034
Lep leptin 0.027
Col1a1 collagen, type I, alpha 1 0.025
Adam17 a disintegrin and metallopeptidase domain 17 0.024
Igf1r insulin-like growth factor I receptor 0.023
Nos3 nitric oxide synthase 3, endothelial cell 0.023
Egfr epidermal growth factor receptor 0.022
Kdm2b lysine (K)-specific demethylase 2B 0.021
Fshr follicle stimulating hormone receptor 0.020
Irs2 insulin receptor substrate 2 0.020
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.018
Esr2 estrogen receptor 2 (beta) 0.018
Cav1 caveolin 1, caveolae protein 0.017
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.015
Tlr4 toll-like receptor 4 0.015
Nostrin nitric oxide synthase trafficker 0.014
Npc1 Niemann Pick type C1 0.013
Pparg peroxisome proliferator activated receptor gamma 0.013
Epas1 endothelial PAS domain protein 1 0.013
Csf1 colony stimulating factor 1 (macrophage) 0.013
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.012
Kiss1 KiSS-1 metastasis-suppressor 0.012
Foxa2 forkhead box A2 0.011
Igf2 insulin-like growth factor 2 0.011
Egln1 EGL nine homolog 1 (C. elegans) 0.011
Foxo1 forkhead box O1 0.011
Kl klotho 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism