Process View
The network for 'positive regulation of hormone biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| EPAS1 | endothelial PAS domain protein 1 | 1.000 | |
| CSH1 | chorionic somatomammotropin hormone 1 (placental lactogen) | 1.000 | |
| EGLN1 | egl nine homolog 1 (C. elegans) | 0.999 | |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.999 | |
| AHR | aryl hydrocarbon receptor | 0.997 | |
| VHL | von Hippel-Lindau tumor suppressor | 0.993 | |
| CSH2 | chorionic somatomammotropin hormone 2 | 0.992 | |
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.989 | |
| EGLN3 | egl nine homolog 3 (C. elegans) | 0.986 | |
| GH1 | growth hormone 1 | 0.980 | |
| CLOCK | clock homolog (mouse) | 0.962 | |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.916 | |
| ITGB1BP3 | integrin beta 1 binding protein 3 | 0.896 | |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.872 | |
| CSHL1 | chorionic somatomammotropin hormone-like 1 | 0.847 | |
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.835 | |
| GH2 | growth hormone 2 | 0.718 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.713 | |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.625 | |
| MYO6 | myosin VI | 0.585 | |
| KAT2B | K(lysine) acetyltransferase 2B | 0.490 | |
| RB1 | retinoblastoma 1 | 0.480 | |
| HDAC1 | histone deacetylase 1 | 0.457 | |
| SSX4 | synovial sarcoma, X breakpoint 4 | 0.433 | |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.415 | |
| NOG | noggin | 0.404 | |
| FGF18 | fibroblast growth factor 18 | 0.399 | |
| MTA3 | metastasis associated 1 family, member 3 | 0.395 | |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 0.367 | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.346 | |
| PRMT6 | protein arginine methyltransferase 6 | 0.343 | |
| MTA1 | metastasis associated 1 | 0.338 | |
| MMP11 | matrix metallopeptidase 11 (stromelysin 3) | 0.325 | |
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.291 | |
| INSR | insulin receptor | 0.289 | |
| SMAD3 | SMAD family member 3 | 0.278 | |
| WNT1 | wingless-type MMTV integration site family, member 1 | 0.274 | |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor | 0.258 | |
| IHH | Indian hedgehog | 0.258 | |
| FGF4 | fibroblast growth factor 4 | 0.248 | |
| ESR1 | estrogen receptor 1 | 0.232 | |
| BMP4 | bone morphogenetic protein 4 | 0.223 | |
| IRS1 | insulin receptor substrate 1 | 0.222 | |
| WIF1 | WNT inhibitory factor 1 | 0.221 | |
| SOX21 | SRY (sex determining region Y)-box 21 | 0.204 | |
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.197 | |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.193 | |
| DLX4 | distal-less homeobox 4 | 0.171 | |
| HES2 | hairy and enhancer of split 2 (Drosophila) | 0.169 | |
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.157 | |
| SAMD3 | sterile alpha motif domain containing 3 | 0.156 | |
| RCOR1 | REST corepressor 1 | 0.156 | |
| FOXD3 | forkhead box D3 | 0.132 | |
| CSK | c-src tyrosine kinase | 0.132 | |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.124 | |
| TG | thyroglobulin | 0.122 | |
| AQP5 | aquaporin 5 | 0.121 | |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 | 0.116 | |
| GHR | growth hormone receptor | 0.112 | |
| PGRMC1 | progesterone receptor membrane component 1 | 0.109 | |
| LOXL4 | lysyl oxidase-like 4 | 0.103 | |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.101 | |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.097 | |
| ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | 0.097 | |
| GAB1 | GRB2-associated binding protein 1 | 0.095 | |
| ELL | elongation factor RNA polymerase II | 0.095 | |
| OFCC1 | orofacial cleft 1 candidate 1 | 0.094 | |
| COL2A1 | collagen, type II, alpha 1 | 0.093 | |
| AR | androgen receptor | 0.093 | |
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.092 | |
| BARX1 | BARX homeobox 1 | 0.092 | |
| HOXB1 | homeobox B1 | 0.089 | |
| ADRA1D | adrenergic, alpha-1D-, receptor | 0.089 | |
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.088 | |
| CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 | 0.087 | |
| NPAS2 | neuronal PAS domain protein 2 | 0.086 | |
| SP1 | Sp1 transcription factor | 0.083 | |
| ALX4 | ALX homeobox 4 | 0.082 | |
| SOX1 | SRY (sex determining region Y)-box 1 | 0.078 | |
| TACR1 | tachykinin receptor 1 | 0.077 | |
| SCRT1 | scratch homolog 1, zinc finger protein (Drosophila) | 0.077 | |
| PAX3 | paired box 3 | 0.076 | |
| HS3ST6 | heparan sulfate (glucosamine) 3-O-sulfotransferase 6 | 0.075 | |
| P2RX2 | purinergic receptor P2X, ligand-gated ion channel, 2 | 0.074 | |
| PAX7 | paired box 7 | 0.074 | |
| NCOA7 | nuclear receptor coactivator 7 | 0.073 | |
| WNT10A | wingless-type MMTV integration site family, member 10A | 0.073 | |
| GRIK3 | glutamate receptor, ionotropic, kainate 3 | 0.072 | |
| HCRTR1 | hypocretin (orexin) receptor 1 | 0.072 | |
| CCDC48 | coiled-coil domain containing 48 | 0.072 | |
| GDNF | glial cell derived neurotrophic factor | 0.072 | |
| NCOA6 | nuclear receptor coactivator 6 | 0.071 | |
| TBX5 | T-box 5 | 0.068 | |
| EGFR | epidermal growth factor receptor | 0.066 | |
| KCNQ2 | potassium voltage-gated channel, KQT-like subfamily, member 2 | 0.065 | |
| SNAI1 | snail homolog 1 (Drosophila) | 0.064 | |
| GLI1 | GLI family zinc finger 1 | 0.064 | |
| CYP11A1 | cytochrome P450, family 11, subfamily A, polypeptide 1 | 0.063 | |
| HOXC8 | homeobox C8 | 0.063 | |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | 0.061 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ghr | growth hormone receptor | 0.886 | |
| Grb10 | growth factor receptor bound protein 10 | 0.348 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.221 | |
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.190 | |
| Igf2r | insulin-like growth factor 2 receptor | 0.153 | |
| Lepr | leptin receptor | 0.086 | |
| Ahr | aryl-hydrocarbon receptor | 0.053 | |
| Insr | insulin receptor | 0.042 | |
| Ar | androgen receptor | 0.039 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.036 | |
| Vhl | von Hippel-Lindau tumor suppressor | 0.034 | |
| Lep | leptin | 0.027 | |
| Col1a1 | collagen, type I, alpha 1 | 0.025 | |
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.024 | |
| Igf1r | insulin-like growth factor I receptor | 0.023 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.023 | |
| Egfr | epidermal growth factor receptor | 0.022 | |
| Kdm2b | lysine (K)-specific demethylase 2B | 0.021 | |
| Fshr | follicle stimulating hormone receptor | 0.020 | |
| Irs2 | insulin receptor substrate 2 | 0.020 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.018 | |
| Esr2 | estrogen receptor 2 (beta) | 0.018 | |
| Cav1 | caveolin 1, caveolae protein | 0.017 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.015 | |
| Tlr4 | toll-like receptor 4 | 0.015 | |
| Nostrin | nitric oxide synthase trafficker | 0.014 | |
| Npc1 | Niemann Pick type C1 | 0.013 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.013 | |
| Epas1 | endothelial PAS domain protein 1 | 0.013 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.013 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.012 | |
| Kiss1 | KiSS-1 metastasis-suppressor | 0.012 | |
| Foxa2 | forkhead box A2 | 0.011 | |
| Igf2 | insulin-like growth factor 2 | 0.011 | |
| Egln1 | EGL nine homolog 1 (C. elegans) | 0.011 | |
| Foxo1 | forkhead box O1 | 0.011 | |
| Kl | klotho | 0.010 |