IMP
Process View
The network for 'physiological muscle hypertrophy' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
physiological muscle hypertrophy
The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.905 | |
| Apc | adenomatosis polyposis coli | 0.754 | |
| Axin1 | axin 1 | 0.617 | |
| Agtr1a | angiotensin II receptor, type 1a | 0.360 | |
| Lepr | leptin receptor | 0.298 | |
| Prkaca | protein kinase, cAMP dependent, catalytic, alpha | 0.176 | |
| Lrrk2 | leucine-rich repeat kinase 2 | 0.153 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.136 | |
| Svep1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | 0.132 | |
| Egfr | epidermal growth factor receptor | 0.119 | |
| Prkar1a | protein kinase, cAMP dependent regulatory, type I, alpha | 0.112 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.108 | |
| Epas1 | endothelial PAS domain protein 1 | 0.092 | |
| Gsk3b | glycogen synthase kinase 3 beta | 0.089 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.088 | |
| Kif1b | kinesin family member 1B | 0.068 | |
| Vav3 | vav 3 oncogene | 0.065 | |
| Ncoa1 | nuclear receptor coactivator 1 | 0.062 | |
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.055 | |
| Mef2a | myocyte enhancer factor 2A | 0.054 | |
| Mll3 | myeloid/lymphoid or mixed-lineage leukemia 3 | 0.051 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.049 | |
| Itgbl1 | integrin, beta-like 1 | 0.049 | |
| Vegfa | vascular endothelial growth factor A | 0.048 | |
| Hivep2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.048 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.045 | |
| Srpx | sushi-repeat-containing protein | 0.042 | |
| Slc23a2 | solute carrier family 23 (nucleobase transporters), member 2 | 0.039 | |
| Kcne4 | potassium voltage-gated channel, Isk-related subfamily, gene 4 | 0.039 | |
| Apoe | apolipoprotein E | 0.039 | |
| Agtr2 | angiotensin II receptor, type 2 | 0.038 | |
| Col16a1 | collagen, type XVI, alpha 1 | 0.037 | |
| Adamts2 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2 | 0.037 | |
| Mtmr1 | myotubularin related protein 1 | 0.036 | |
| Scn7a | sodium channel, voltage-gated, type VII, alpha | 0.036 | |
| Braf | Braf transforming gene | 0.036 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.033 | |
| Tgfb1 | transforming growth factor, beta 1 | 0.032 | |
| Meox2 | mesenchyme homeobox 2 | 0.031 | |
| Cpz | carboxypeptidase Z | 0.031 | |
| Vav2 | vav 2 oncogene | 0.030 | |
| Igf1 | insulin-like growth factor 1 | 0.030 | |
| Hoxd8 | homeobox D8 | 0.029 | |
| Tfpi2 | tissue factor pathway inhibitor 2 | 0.028 | |
| Umod | uromodulin | 0.028 | |
| Slc14a2 | solute carrier family 14 (urea transporter), member 2 | 0.027 | |
| Mapk9 | mitogen-activated protein kinase 9 | 0.027 | |
| Il6st | interleukin 6 signal transducer | 0.027 | |
| Egln3 | EGL nine homolog 3 (C. elegans) | 0.027 | |
| Adrb2 | adrenergic receptor, beta 2 | 0.026 | |
| Kpna1 | karyopherin (importin) alpha 1 | 0.026 | |
| Vdr | vitamin D receptor | 0.026 | |
| Col6a3 | collagen, type VI, alpha 3 | 0.026 | |
| Htt | huntingtin | 0.026 | |
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.026 | |
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.026 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.026 | |
| Atp2b1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.025 | |
| Fbxo43 | F-box protein 43 | 0.025 | |
| Tcf7l2 | transcription factor 7-like 2, T-cell specific, HMG-box | 0.025 | |
| Col11a1 | collagen, type XI, alpha 1 | 0.024 | |
| Thbs2 | thrombospondin 2 | 0.024 | |
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.024 | |
| Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.024 | |
| Nf2 | neurofibromatosis 2 | 0.023 | |
| Wnk4 | WNK lysine deficient protein kinase 4 | 0.023 | |
| Slc12a1 | solute carrier family 12, member 1 | 0.023 | |
| Hipk3 | homeodomain interacting protein kinase 3 | 0.023 | |
| Gsk3a | glycogen synthase kinase 3 alpha | 0.022 | |
| Dpt | dermatopontin | 0.022 | |
| Eln | elastin | 0.022 | |
| Fcna | ficolin A | 0.022 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.022 | |
| Arid1b | AT rich interactive domain 1B (SWI-like) | 0.022 | |
| Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) | 0.022 | |
| Pde4d | phosphodiesterase 4D, cAMP specific | 0.021 | |
| Dnajc5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.021 | |
| Angpt4 | angiopoietin 4 | 0.021 | |
| Gatad2b | GATA zinc finger domain containing 2B | 0.020 | |
| Tnxb | tenascin XB | 0.020 | |
| Atp8a1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.020 | |
| Cxcl12 | chemokine (C-X-C motif) ligand 12 | 0.020 | |
| Crh | corticotropin releasing hormone | 0.019 | |
| Pcmtd1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.019 | |
| Col4a4 | collagen, type IV, alpha 4 | 0.019 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.019 | |
| Dkk2 | dickkopf homolog 2 (Xenopus laevis) | 0.019 | |
| Crhr1 | corticotropin releasing hormone receptor 1 | 0.019 | |
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.019 | |
| C1s | complement component 1, s subcomponent | 0.018 | |
| Rab10 | RAB10, member RAS oncogene family | 0.018 | |
| Cyp11b1 | cytochrome P450, family 11, subfamily b, polypeptide 1 | 0.018 | |
| Camk2d | calcium/calmodulin-dependent protein kinase II, delta | 0.017 | |
| Klhl24 | kelch-like 24 (Drosophila) | 0.017 | |
| Fibin | fin bud initiation factor homolog (zebrafish) | 0.017 | |
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.017 | |
| C1qtnf3 | C1q and tumor necrosis factor related protein 3 | 0.017 | |
| Adam18 | a disintegrin and metallopeptidase domain 18 | 0.017 | |
| Fgf7 | fibroblast growth factor 7 | 0.017 | |
| Ddx6 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 | 0.017 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ahsg | alpha-2-HS-glycoprotein | 0.071 | |
| Alb | albumin | 0.047 | |
| LOC100362824 | caveolin 2-like | 0.041 | |
| Cav2 | caveolin 2 | 0.039 | |
| Rup2 | urinary protein 2 | 0.037 | |
| Vom2r27 | vomeronasal 2 receptor, 27 | 0.023 | |
| Cav1 | caveolin 1, caveolae protein | 0.023 | |
| Apoh | apolipoprotein H (beta-2-glycoprotein I) | 0.017 | |
| Spp2 | secreted phosphoprotein 2 | 0.016 | |
| Serpina3k | serine (or cysteine) peptidase inhibitor, clade A, member 3K | 0.016 | |
| Akr1c18 | aldo-keto reductase family 1, member C18 | 0.015 | |
| Proc | protein C | 0.015 | |
| Lif | leukemia inhibitory factor | 0.014 | |
| Psmc3 | proteasome (prosome, macropain) 26S subunit, ATPase 3 | 0.012 | |
| Serpina1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.012 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.012 | |
| Ap2s1 | adaptor-related protein complex 2, sigma 1 subunit | 0.011 | |
| Cckar | cholecystokinin A receptor | 0.011 | |
| Igfals | insulin-like growth factor binding protein, acid labile subunit | 0.011 | |
| Fdft1 | farnesyl diphosphate farnesyl transferase 1 | 0.011 | |
| Gria1 | glutamate receptor, ionotropic, AMPA 1 | 0.011 | |
| Hnmt | histamine N-methyltransferase | 0.010 |