The network for 'lateral line system development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

lateral line system development

The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.

Name Description Probability Func Analog Organism
Espn espin 0.934
Msx1 homeobox, msh-like 1 0.920
Hoxb1 homeobox B1 0.869
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.764
Sox9 SRY-box containing gene 9 0.705
Ush1g Usher syndrome 1G homolog (human) 0.689
Shh sonic hedgehog 0.687
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.687
Tbx1 T-box 1 0.686
Isl1 ISL1 transcription factor, LIM/homeodomain 0.663
Ntf3 neurotrophin 3 0.652
Sox10 SRY-box containing gene 10 0.649
Dlx5 distal-less homeobox 5 0.648
Ret ret proto-oncogene 0.627
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.618
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.599
Neurod1 neurogenic differentiation 1 0.597
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.575
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.567
Il6st interleukin 6 signal transducer 0.564
Hoxa1 homeobox A1 0.556
Nrg1 neuregulin 1 0.548
Mpdz multiple PDZ domain protein 0.540
Pax2 paired box gene 2 0.509
Gsk3b glycogen synthase kinase 3 beta 0.493
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.489
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.481
Phox2b paired-like homeobox 2b 0.473
Hmx3 H6 homeobox 3 0.469
Gdnf glial cell line derived neurotrophic factor 0.447
Neurod4 neurogenic differentiation 4 0.421
Otx2 orthodenticle homolog 2 (Drosophila) 0.406
Ar androgen receptor 0.401
Ebf3 early B-cell factor 3 0.382
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.370
Gbx2 gastrulation brain homeobox 2 0.369
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 0.364
Pax9 paired box gene 9 0.354
Tecta tectorin alpha 0.352
Neurog1 neurogenin 1 0.342
Lepr leptin receptor 0.337
Pbx1 pre B-cell leukemia transcription factor 1 0.301
Ctnnb1 catenin (cadherin associated protein), beta 1 0.291
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.286
Il6 interleukin 6 0.285
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.285
Chrd chordin 0.283
Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 0.276
Eya1 eyes absent 1 homolog (Drosophila) 0.268
Pparg peroxisome proliferator activated receptor gamma 0.268
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.264
Srrm4 serine/arginine repetitive matrix 4 0.257
Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) 0.254
Stat3 signal transducer and activator of transcription 3 0.246
Ap2m1 adaptor protein complex AP-2, mu1 0.244
Hoxa10 homeobox A10 0.240
Egr1 early growth response 1 0.240
Cdh23 cadherin 23 (otocadherin) 0.239
Lrp6 low density lipoprotein receptor-related protein 6 0.238
Gli3 GLI-Kruppel family member GLI3 0.236
Pax3 paired box gene 3 0.235
Lep leptin 0.232
Rac1 RAS-related C3 botulinum substrate 1 0.230
Atp6v0b ATPase, H+ transporting, lysosomal V0 subunit B 0.223
Egr2 early growth response 2 0.223
Runx2 runt related transcription factor 2 0.220
Foxa2 forkhead box A2 0.218
Ghr growth hormone receptor 0.217
Cd44 CD44 antigen 0.207
Tmc1 transmembrane channel-like gene family 1 0.194
Nab2 Ngfi-A binding protein 2 0.193
Col22a1 collagen, type XXII, alpha 1 0.191
Ush1c Usher syndrome 1C homolog (human) 0.191
Neurog2 neurogenin 2 0.187
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.185
Tcfap2c transcription factor AP-2, gamma 0.183
Wnt3a wingless-related MMTV integration site 3A 0.180
Hoxa4 homeobox A4 0.180
Wnt1 wingless-related MMTV integration site 1 0.168
Zic2 zinc finger protein of the cerebellum 2 0.167
Nkx3-2 NK3 homeobox 2 0.167
Hoxd3 homeobox D3 0.165
Junb Jun-B oncogene 0.163
Gli2 GLI-Kruppel family member GLI2 0.162
En1 engrailed 1 0.159
Gas1 growth arrest specific 1 0.158
Wnt5a wingless-related MMTV integration site 5A 0.156
Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 0.154
Grip1 glutamate receptor interacting protein 1 0.153
Ptk7 PTK7 protein tyrosine kinase 7 0.146
Tcf7 transcription factor 7, T-cell specific 0.145
Cyr61 cysteine rich protein 61 0.145
Shox2 short stature homeobox 2 0.145
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.144
Gsc goosecoid homeobox 0.144
Hmx1 H6 homeobox 1 0.142
Gli1 GLI-Kruppel family member GLI1 0.142
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.136
Rtn4r reticulon 4 receptor 0.134
Insm1 insulinoma-associated 1 0.132
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
eya1 eyes absent homolog 1 0.999
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.998
sox10 SRY-box containing gene 10 0.983
hoxc8a homeo box C8a 0.979
lef1 lymphocyte enhancer binding factor 1 0.965
hoxc4a homeo box C4a 0.949
cldnb claudin b 0.938
gria4a glutamate receptor, ionotropic, AMPA 4a 0.930
hoxb8a homeo box B8a 0.927
cldnh claudin h 0.921
pcsk5a proprotein convertase subtilisin/kexin type 5a 0.901
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.878
met met proto-oncogene (hepatocyte growth factor receptor) 0.870
hmx3 homeo box (H6 family) 3 0.868
notch3 notch homolog 3 0.853
cdh6 cadherin 6 0.840
atoh1a atonal homolog 1a 0.830
alcama activated leukocyte cell adhesion molecule a 0.828
epcam epithelial cell adhesion molecule 0.822
kal1a Kallmann syndrome 1a sequence 0.809
hoxb6a homeo box B6a 0.807
hoxb5b homeo box B5b 0.784
foxp1b forkhead box P1b 0.748
hsd17b12a hydroxysteroid (17-beta) dehydrogenase 12a 0.747
hoxa4a homeo box A4a 0.729
spry1 sprouty homolog 1 (Drosophila) 0.726
cxcr4b chemokine (C-X-C motif), receptor 4b 0.712
neurog1 neurogenin 1 0.710
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.693
myo7aa myosin VIIAa 0.681
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.679
hoxd4a homeo box D4a 0.669
scn1bb sodium channel, voltage-gated, type I, beta b 0.637
hoxb6b homeo box B6b 0.618
tnfsf10l3 tumor necrosis factor (ligand) superfamily, member 10 like 3 0.604
nrg1 neuregulin 1 0.597
fgf3 fibroblast growth factor 3 0.592
gbx2 gastrulation brain homeo box 2 0.589
hnf1ba HNF1 homeobox Ba 0.575
gria4b glutamate receptor, ionotropic, AMPA 4b 0.571
lmx1b.2 LIM homeobox transcription factor 1, beta 2 0.557
fgf10a fibroblast growth factor 10a 0.532
hoxb4a homeo box B4a 0.530
dkk1b dickkopf 1b 0.527
cldn7b claudin 7b 0.508
kdrl kinase insert domain receptor like 0.499
rorb RAR-related orphan receptor B 0.495
spint1a serine peptidase inhibitor, Kunitz type 1 a 0.480
wnt4a wingless-type MMTV integration site family, member 4a 0.477
grhl2b grainyhead-like 2b (Drosophila) 0.476
gata3 GATA-binding protein 3 0.471
si:dkeyp-7c9.1 si:dkeyp-7c9.1 0.471
irx2a iroquois homeobox protein 2, a 0.454
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.443
hoxb5a homeo box B5a 0.433
sncb synuclein, beta 0.423
gpr126 G protein-coupled receptor 126 0.423
cntn2 contactin 2 0.418
egr1 early growth response 1 0.417
irx1b iroquois homeobox protein 1, b 0.415
gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 0.402
pcsk9 proprotein convertase subtilisin/kexin type 9 0.396
ndrg1 N-myc downstream regulated gene 1 0.391
gria1a glutamate receptor, ionotropic, AMPA 1a 0.389
atoh1b atonal homolog 1b 0.388
pcsk5b proprotein convertase subtilisin/kexin type 5b 0.387
mbp myelin basic protein 0.386
prox1 prospero-related homeobox gene 1 0.386
hapln1a hyaluronan and proteoglycan link protein 1a 0.383
epha7 eph receptor A7 0.376
hoxb10a homeo box B10a 0.364
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.364
hhip hedgehog interacting protein 0.362
wif1 wnt inhibitory factor 1 0.355
ptmab prothymosin, alpha b 0.350
fzd10 frizzled homolog 10 0.349
slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 0.349
cdx4 caudal type homeo box transcription factor 4 0.348
hoxc6a homeo box C6a 0.344
kif17 kinesin family member 17 0.334
neurod neurogenic differentiation 0.334
foxj1a forkhead box J1a 0.332
mab21l2 mab-21-like 2 0.331
sox2 SRY-box containing gene 2 0.321
wnt3 wingless-type MMTV integration site family, member 3 0.318
phox2a paired-like homeobox 2a 0.315
cldn8 claudin 8 0.315
cx27.5 connexin 27.5 0.314
hmx4 H6 family homeobox 4 0.312
pcsk1 proprotein convertase subtilisin/kexin type 1 0.310
pcsk7 proprotein convertase subtilisin/kexin type 7 0.305
pcsk2 proprotein convertase subtilisin/kexin type 2 0.298
jag1b jagged 1b 0.297
ptf1a pancreas specific transcription factor, 1a 0.291
hoxb3a homeo box B3a 0.287
ptgs1 prostaglandin-endoperoxide synthase 1 0.286
dla deltaA 0.282
ddc dopa decarboxylase 0.281
wnt1 wingless-type MMTV integration site family, member 1 0.281
fabp11a fatty acid binding protein 11a 0.279
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism