IMP
Process View
The network for 'cerebral cortex neuron differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
cerebral cortex neuron differentiation
The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Otx2 | orthodenticle homolog 2 (Drosophila) | 1.000 | |
| Shh | sonic hedgehog | 1.000 | |
| Pax6 | paired box gene 6 | 1.000 | |
| Dlx5 | distal-less homeobox 5 | 1.000 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 1.000 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 1.000 | |
| Foxg1 | forkhead box G1 | 1.000 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 1.000 | |
| Msx1 | homeobox, msh-like 1 | 1.000 | |
| Gli3 | GLI-Kruppel family member GLI3 | 1.000 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
| Foxc1 | forkhead box C1 | 1.000 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 1.000 | |
| Sox2 | SRY-box containing gene 2 | 1.000 | |
| Tcfap2a | transcription factor AP-2, alpha | 1.000 | |
| Fgf8 | fibroblast growth factor 8 | 1.000 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.999 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.999 | |
| Pax2 | paired box gene 2 | 0.999 | |
| Tbx1 | T-box 1 | 0.999 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.999 | |
| Pax3 | paired box gene 3 | 0.998 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.998 | |
| Tbx3 | T-box 3 | 0.997 | |
| Foxc2 | forkhead box C2 | 0.997 | |
| Sox9 | SRY-box containing gene 9 | 0.996 | |
| Prrx1 | paired related homeobox 1 | 0.994 | |
| Nog | noggin | 0.992 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.992 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.991 | |
| Hoxa1 | homeobox A1 | 0.981 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.981 | |
| Dlx2 | distal-less homeobox 2 | 0.973 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.971 | |
| Dlx6 | distal-less homeobox 6 | 0.970 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.965 | |
| Bmp4 | bone morphogenetic protein 4 | 0.953 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.944 | |
| Nodal | nodal | 0.939 | |
| Lhx9 | LIM homeobox protein 9 | 0.934 | |
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.933 | |
| Fgf10 | fibroblast growth factor 10 | 0.928 | |
| Sox11 | SRY-box containing gene 11 | 0.919 | |
| Msx2 | homeobox, msh-like 2 | 0.911 | |
| Lhx5 | LIM homeobox protein 5 | 0.910 | |
| Pten | phosphatase and tensin homolog | 0.907 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.904 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.903 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.891 | |
| Id1 | inhibitor of DNA binding 1 | 0.884 | |
| Gsc | goosecoid homeobox | 0.873 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.872 | |
| Six3 | sine oculis-related homeobox 3 homolog (Drosophila) | 0.870 | |
| Chrd | chordin | 0.861 | |
| Neurog2 | neurogenin 2 | 0.849 | |
| Pax9 | paired box gene 9 | 0.836 | |
| Neurod1 | neurogenic differentiation 1 | 0.828 | |
| Lhx3 | LIM homeobox protein 3 | 0.818 | |
| Runx2 | runt related transcription factor 2 | 0.810 | |
| Id3 | inhibitor of DNA binding 3 | 0.806 | |
| Dlx1 | distal-less homeobox 1 | 0.803 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.798 | |
| Sall4 | sal-like 4 (Drosophila) | 0.785 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.785 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.777 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.765 | |
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.749 | |
| Sall3 | sal-like 3 (Drosophila) | 0.739 | |
| Bdnf | brain derived neurotrophic factor | 0.736 | |
| Trp63 | transformation related protein 63 | 0.729 | |
| Hoxd3 | homeobox D3 | 0.722 | |
| Psen1 | presenilin 1 | 0.721 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.712 | |
| Jag1 | jagged 1 | 0.709 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.697 | |
| Hoxa2 | homeobox A2 | 0.696 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.675 | |
| Adrb1 | adrenergic receptor, beta 1 | 0.675 | |
| Tlx3 | T-cell leukemia, homeobox 3 | 0.674 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.670 | |
| Oprm1 | opioid receptor, mu 1 | 0.665 | |
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.661 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.641 | |
| Rarb | retinoic acid receptor, beta | 0.638 | |
| Lhx6 | LIM homeobox protein 6 | 0.629 | |
| Bmp7 | bone morphogenetic protein 7 | 0.623 | |
| Hoxb1 | homeobox B1 | 0.595 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.595 | |
| T | brachyury | 0.590 | |
| Insm1 | insulinoma-associated 1 | 0.588 | |
| Nr2e1 | nuclear receptor subfamily 2, group E, member 1 | 0.588 | |
| Wt1 | Wilms tumor 1 homolog | 0.572 | |
| Sox3 | SRY-box containing gene 3 | 0.563 | |
| Gata3 | GATA binding protein 3 | 0.562 | |
| Fgf3 | fibroblast growth factor 3 | 0.561 | |
| Pax8 | paired box gene 8 | 0.530 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.523 | |
| Lhx1 | LIM homeobox protein 1 | 0.511 | |
| Gata4 | GATA binding protein 4 | 0.500 | |
| Uncx | UNC homeobox | 0.494 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.386 | |
| PKP4 | plakophilin 4 | 0.337 | |
| NDEL1 | nudE nuclear distribution gene E homolog (A. nidulans)-like 1 | 0.264 | |
| FLNB | filamin B, beta | 0.157 | |
| NCSTN | nicastrin | 0.100 | |
| PEX14 | peroxisomal biogenesis factor 14 | 0.089 | |
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.079 | |
| WDYHV1 | WDYHV motif containing 1 | 0.079 | |
| PEX12 | peroxisomal biogenesis factor 12 | 0.071 | |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.069 | |
| APH1A | anterior pharynx defective 1 homolog A (C. elegans) | 0.063 | |
| PRTFDC1 | phosphoribosyl transferase domain containing 1 | 0.041 | |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.040 | |
| PAX8 | paired box 8 | 0.039 | |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.036 | |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.031 | |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 0.026 | |
| TCF4 | transcription factor 4 | 0.022 | |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.016 | |
| ATXN3 | ataxin 3 | 0.014 | |
| APP | amyloid beta (A4) precursor protein | 0.014 | |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 | 0.013 | |
| BCL2L1 | BCL2-like 1 | 0.012 | |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 0.011 | |
| PSENEN | presenilin enhancer 2 homolog (C. elegans) | 0.011 | |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | 0.011 | |
| TRIP13 | thyroid hormone receptor interactor 13 | 0.011 | |
| PEX19 | peroxisomal biogenesis factor 19 | 0.011 |