The network for 'rhombomere 2 development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

rhombomere 2 development

The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.

Name Description Probability Func Analog Organism
Hoxa1 homeobox A1 1.000
Eya1 eyes absent 1 homolog (Drosophila) 1.000
Hoxa2 homeobox A2 1.000
Tbx1 T-box 1 1.000
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 1.000
Pax2 paired box gene 2 0.999
Foxc2 forkhead box C2 0.996
Otx2 orthodenticle homolog 2 (Drosophila) 0.995
Pax3 paired box gene 3 0.995
Tcfap2a transcription factor AP-2, alpha 0.994
Fgf8 fibroblast growth factor 8 0.994
Shh sonic hedgehog 0.994
Gbx2 gastrulation brain homeobox 2 0.989
Foxc1 forkhead box C1 0.982
Hoxa3 homeobox A3 0.982
Foxg1 forkhead box G1 0.980
Dlx5 distal-less homeobox 5 0.975
Prrx1 paired related homeobox 1 0.965
Gli3 GLI-Kruppel family member GLI3 0.953
Msx1 homeobox, msh-like 1 0.953
Ednra endothelin receptor type A 0.946
Hand2 heart and neural crest derivatives expressed transcript 2 0.913
Bmp4 bone morphogenetic protein 4 0.881
Isl1 ISL1 transcription factor, LIM/homeodomain 0.875
Pitx2 paired-like homeodomain transcription factor 2 0.866
Smo smoothened homolog (Drosophila) 0.847
Fgfr2 fibroblast growth factor receptor 2 0.844
Lmx1a LIM homeobox transcription factor 1 alpha 0.811
Hoxd3 homeobox D3 0.807
Jag1 jagged 1 0.787
Chd7 chromodomain helicase DNA binding protein 7 0.775
Hoxb1 homeobox B1 0.758
Fgf10 fibroblast growth factor 10 0.743
Hoxb2 homeobox B2 0.737
Otx1 orthodenticle homolog 1 (Drosophila) 0.719
Gsc goosecoid homeobox 0.667
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.624
Hmx3 H6 homeobox 3 0.618
Chrd chordin 0.590
Rarb retinoic acid receptor, beta 0.577
Sox9 SRY-box containing gene 9 0.563
Hand1 heart and neural crest derivatives expressed transcript 1 0.542
Hoxb3 homeobox B3 0.474
Wnt1 wingless-related MMTV integration site 1 0.472
Rarg retinoic acid receptor, gamma 0.454
En1 engrailed 1 0.435
Fgf3 fibroblast growth factor 3 0.422
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.418
Fgfr1 fibroblast growth factor receptor 1 0.416
Zeb1 zinc finger E-box binding homeobox 1 0.373
Sox2 SRY-box containing gene 2 0.347
Msx2 homeobox, msh-like 2 0.339
Tgfb2 transforming growth factor, beta 2 0.328
Gata3 GATA binding protein 3 0.320
Vangl2 vang-like 2 (van gogh, Drosophila) 0.292
Prrx2 paired related homeobox 2 0.290
Pax9 paired box gene 9 0.224
Pax6 paired box gene 6 0.220
Rara retinoic acid receptor, alpha 0.208
Phox2b paired-like homeobox 2b 0.198
Dlx2 distal-less homeobox 2 0.197
Tbx10 T-box 10 0.195
Gli2 GLI-Kruppel family member GLI2 0.190
Ntf3 neurotrophin 3 0.165
Efnb2 ephrin B2 0.149
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.148
Nog noggin 0.138
Bmp7 bone morphogenetic protein 7 0.101
Zic3 zinc finger protein of the cerebellum 3 0.093
T brachyury 0.092
Hoxc4 homeobox C4 0.091
Sox11 SRY-box containing gene 11 0.090
Vegfa vascular endothelial growth factor A 0.087
Hoxc8 homeobox C8 0.086
Pbx1 pre B-cell leukemia transcription factor 1 0.086
En2 engrailed 2 0.083
Hoxb5 homeobox B5 0.083
Emx2 empty spiracles homolog 2 (Drosophila) 0.081
Hoxa5 homeobox A5 0.074
Hmx2 H6 homeobox 2 0.074
Hoxd11 homeobox D11 0.066
Hoxb6 homeobox B6 0.066
Bdnf brain derived neurotrophic factor 0.066
Pax8 paired box gene 8 0.065
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.062
Zic2 zinc finger protein of the cerebellum 2 0.062
Ece1 endothelin converting enzyme 1 0.061
Tgfbr2 transforming growth factor, beta receptor II 0.060
Lmx1b LIM homeobox transcription factor 1 beta 0.060
Lhx1 LIM homeobox protein 1 0.059
Hoxd1 homeobox D1 0.059
Dlx6 distal-less homeobox 6 0.058
Sall4 sal-like 4 (Drosophila) 0.056
Hoxa4 homeobox A4 0.053
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.052
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.051
Foxi1 forkhead box I1 0.050
Mesp1 mesoderm posterior 1 0.050
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.049
Mecom MDS1 and EVI1 complex locus 0.048
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism