Process View
The network for 'rhombomere 2 development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Hoxa1 | homeobox A1 | 1.000 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 1.000 | |
| Hoxa2 | homeobox A2 | 1.000 | |
| Tbx1 | T-box 1 | 1.000 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 1.000 | |
| Pax2 | paired box gene 2 | 0.999 | |
| Foxc2 | forkhead box C2 | 0.996 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.995 | |
| Pax3 | paired box gene 3 | 0.995 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.994 | |
| Fgf8 | fibroblast growth factor 8 | 0.994 | |
| Shh | sonic hedgehog | 0.994 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.989 | |
| Foxc1 | forkhead box C1 | 0.982 | |
| Hoxa3 | homeobox A3 | 0.982 | |
| Foxg1 | forkhead box G1 | 0.980 | |
| Dlx5 | distal-less homeobox 5 | 0.975 | |
| Prrx1 | paired related homeobox 1 | 0.965 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.953 | |
| Msx1 | homeobox, msh-like 1 | 0.953 | |
| Ednra | endothelin receptor type A | 0.946 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.913 | |
| Bmp4 | bone morphogenetic protein 4 | 0.881 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.875 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.866 | |
| Smo | smoothened homolog (Drosophila) | 0.847 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.844 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.811 | |
| Hoxd3 | homeobox D3 | 0.807 | |
| Jag1 | jagged 1 | 0.787 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.775 | |
| Hoxb1 | homeobox B1 | 0.758 | |
| Fgf10 | fibroblast growth factor 10 | 0.743 | |
| Hoxb2 | homeobox B2 | 0.737 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.719 | |
| Gsc | goosecoid homeobox | 0.667 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.624 | |
| Hmx3 | H6 homeobox 3 | 0.618 | |
| Chrd | chordin | 0.590 | |
| Rarb | retinoic acid receptor, beta | 0.577 | |
| Sox9 | SRY-box containing gene 9 | 0.563 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.542 | |
| Hoxb3 | homeobox B3 | 0.474 | |
| Wnt1 | wingless-related MMTV integration site 1 | 0.472 | |
| Rarg | retinoic acid receptor, gamma | 0.454 | |
| En1 | engrailed 1 | 0.435 | |
| Fgf3 | fibroblast growth factor 3 | 0.422 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.418 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.416 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.373 | |
| Sox2 | SRY-box containing gene 2 | 0.347 | |
| Msx2 | homeobox, msh-like 2 | 0.339 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.328 | |
| Gata3 | GATA binding protein 3 | 0.320 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.292 | |
| Prrx2 | paired related homeobox 2 | 0.290 | |
| Pax9 | paired box gene 9 | 0.224 | |
| Pax6 | paired box gene 6 | 0.220 | |
| Rara | retinoic acid receptor, alpha | 0.208 | |
| Phox2b | paired-like homeobox 2b | 0.198 | |
| Dlx2 | distal-less homeobox 2 | 0.197 | |
| Tbx10 | T-box 10 | 0.195 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.190 | |
| Ntf3 | neurotrophin 3 | 0.165 | |
| Efnb2 | ephrin B2 | 0.149 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.148 | |
| Nog | noggin | 0.138 | |
| Bmp7 | bone morphogenetic protein 7 | 0.101 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.093 | |
| T | brachyury | 0.092 | |
| Hoxc4 | homeobox C4 | 0.091 | |
| Sox11 | SRY-box containing gene 11 | 0.090 | |
| Vegfa | vascular endothelial growth factor A | 0.087 | |
| Hoxc8 | homeobox C8 | 0.086 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.086 | |
| En2 | engrailed 2 | 0.083 | |
| Hoxb5 | homeobox B5 | 0.083 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.081 | |
| Hoxa5 | homeobox A5 | 0.074 | |
| Hmx2 | H6 homeobox 2 | 0.074 | |
| Hoxd11 | homeobox D11 | 0.066 | |
| Hoxb6 | homeobox B6 | 0.066 | |
| Bdnf | brain derived neurotrophic factor | 0.066 | |
| Pax8 | paired box gene 8 | 0.065 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.062 | |
| Zic2 | zinc finger protein of the cerebellum 2 | 0.062 | |
| Ece1 | endothelin converting enzyme 1 | 0.061 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.060 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.060 | |
| Lhx1 | LIM homeobox protein 1 | 0.059 | |
| Hoxd1 | homeobox D1 | 0.059 | |
| Dlx6 | distal-less homeobox 6 | 0.058 | |
| Sall4 | sal-like 4 (Drosophila) | 0.056 | |
| Hoxa4 | homeobox A4 | 0.053 | |
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.052 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.051 | |
| Foxi1 | forkhead box I1 | 0.050 | |
| Mesp1 | mesoderm posterior 1 | 0.050 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.049 | |
| Mecom | MDS1 and EVI1 complex locus | 0.048 |