The network for 'germline stem cell asymmetric division' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

germline stem cell asymmetric division

The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes.

Mus musculus
Name Description Probability Func Analog Organism
Grb10 growth factor receptor bound protein 10 0.966
Lepr leptin receptor 0.669
Irs2 insulin receptor substrate 2 0.529
Kiss1 KiSS-1 metastasis-suppressor 0.470
Ghr growth hormone receptor 0.376
Insr insulin receptor 0.129
Hoxa10 homeobox A10 0.110
Irs1 insulin receptor substrate 1 0.109
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.106
Igf1r insulin-like growth factor I receptor 0.103
Ins2 insulin II 0.080
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.079
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.073
Zfp592 zinc finger protein 592 0.070
Lep leptin 0.059
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.055
Pparg peroxisome proliferator activated receptor gamma 0.055
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.050
Thra thyroid hormone receptor alpha 0.049
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.037
Lipe lipase, hormone sensitive 0.036
Hrh1 histamine receptor H1 0.033
Igf2r insulin-like growth factor 2 receptor 0.029
Nos3 nitric oxide synthase 3, endothelial cell 0.028
Sik3 SIK family kinase 3 0.027
Npc1 Niemann Pick type C1 0.027
Nos1 nitric oxide synthase 1, neuronal 0.027
Pnpla2 patatin-like phospholipase domain containing 2 0.025
Esr1 estrogen receptor 1 (alpha) 0.024
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.024
Rsph6a radial spoke head 6 homolog A (Chlamydomonas) 0.022
Mark2 MAP/microtubule affinity-regulating kinase 2 0.022
Ar androgen receptor 0.022
Cav1 caveolin 1, caveolae protein 0.022
Kifc2 kinesin family member C2 0.021
Sim1 single-minded homolog 1 (Drosophila) 0.021
Tsx testis specific X-linked gene 0.019
Wnt5a wingless-related MMTV integration site 5A 0.019
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.018
Gli3 GLI-Kruppel family member GLI3 0.018
H1foo H1 histone family, member O, oocyte-specific 0.017
Igf2 insulin-like growth factor 2 0.016
Map3k6 mitogen-activated protein kinase kinase kinase 6 0.016
Rest RE1-silencing transcription factor 0.016
Pbx1 pre B-cell leukemia transcription factor 1 0.016
Bmpr2 bone morphogenic protein receptor, type II (serine/threonine kinase) 0.015
4930549C01Rik RIKEN cDNA 4930549C01 gene 0.015
Gck glucokinase 0.015
Neo1 neogenin 0.014
Mael maelstrom homolog (Drosophila) 0.013
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.013
Pou5f1 POU domain, class 5, transcription factor 1 0.013
Tex14 testis expressed gene 14 0.012
Piwil2 piwi-like homolog 2 (Drosophila) 0.012
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.012
Brd4 bromodomain containing 4 0.012
Fgf21 fibroblast growth factor 21 0.012
Dnmt3l DNA (cytosine-5-)-methyltransferase 3-like 0.012
Lhx3 LIM homeobox protein 3 0.011
Hoxd11 homeobox D11 0.011
Fzd4 frizzled homolog 4 (Drosophila) 0.011
Zfhx3 zinc finger homeobox 3 0.011
Kiss1r KISS1 receptor 0.011
Hoxa11 homeobox A11 0.010
Trp53bp2 transformation related protein 53 binding protein 2 0.010
Sorbs1 sorbin and SH3 domain containing 1 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
brat brain tumor 0.971
pelo pelota 0.934
nos nanos 0.900
Ote Otefin 0.895
bam bag of marbles 0.871
twin CG31137 gene product from transcript CG31137-RB 0.812
zpg zero population growth 0.691
piwi CG6122 gene product from transcript CG6122-RA 0.667
egg eggless 0.628
loqs loquacious 0.562
eff effete 0.411
CSN4 COP9 complex homolog subunit 4 0.347
vas vasa 0.329
stwl stonewall 0.258
bgcn benign gonial cell neoplasm 0.238
stet stem cell tumor 0.145
aret arrest 0.137
pzg putzig 0.135
jeb jelly belly 0.122
wcd wicked 0.108
hts hu li tai shao 0.096
Hmgcr HMG Coenzyme A reductase 0.091
stl stall 0.081
spn-E spindle E 0.080
Cap-G CG34438 gene product from transcript CG34438-RF 0.076
CG8443 CG8443 gene product from transcript CG8443-RA 0.075
Zfrp8 Zinc finger protein RP-8 0.070
chb chromosome bows 0.067
RanBPM Ran-binding protein M 0.062
Akt1 CG4006 gene product from transcript CG4006-RA 0.059
Parg Poly(ADP-ribose) glycohydrolase 0.055
mxc multi sex combs 0.053
inx2 innexin 2 0.052
enok enoki mushroom 0.050
Nf1 Neurofibromin 1 0.048
CG4771 CG4771 gene product from transcript CG4771-RA 0.048
tld tolloid 0.047
fs(1)Yb female sterile (1) Yb 0.043
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.042
Nop60B Nucleolar protein at 60B 0.041
chic chickadee 0.039
Top1 Topoisomerase 1 0.038
tkv thickveins 0.038
ord orientation disruptor 0.036
alphaTub84B alpha-Tubulin at 84B 0.036
gpp grappa 0.035
Hrb98DE Heterogeneous nuclear ribonucleoprotein at 98DE 0.034
Hsp83 Heat shock protein 83 0.034
sfl sulfateless 0.031
inaC inactivation no afterpotential C 0.029
CG18316 CG18316 gene product from transcript CG18316-RA 0.028
InR Insulin-like receptor 0.028
otu ovarian tumor 0.026
dhd deadhead 0.026
wisp wispy 0.025
Mob2 CG11711 gene product from transcript CG11711-RC 0.025
jar jaguar 0.025
Arf79F ADP ribosylation factor 79F 0.024
zuc zucchini 0.024
cutlet CG33122 gene product from transcript CG33122-RA 0.024
RpS3 Ribosomal protein S3 0.024
cuff cutoff 0.022
Dad Daughters against dpp 0.022
cbt cabut 0.022
AGO1 Argonaute-1 0.020
luna CG33473 gene product from transcript CG33473-RB 0.020
Rbp9 RNA-binding protein 9 0.020
pyd polychaetoid 0.019
Fmr1 CG6203 gene product from transcript CG6203-RC 0.019
Peb Protein ejaculatory bulb 0.019
rl rolled 0.019
scny scrawny 0.019
alphaTub67C alpha-Tubulin at 67C 0.018
MAN1 CG3167 gene product from transcript CG3167-RA 0.018
qua quail 0.017
unk unkempt 0.017
stil stand still 0.016
slif slimfast 0.016
Snoo Sno oncogene 0.016
fzy fizzy 0.016
brp bruchpilot 0.015
pigs pickled eggs 0.015
Wnt4 Wnt oncogene analog 4 0.014
Poc1 Proteome of centrioles 1 0.013
CG12256 CG12256 gene product from transcript CG12256-RA 0.013
svp seven up 0.013
can cannonball 0.013
hiw highwire 0.013
gnu giant nuclei 0.013
HP6 Heterochromatin protein 6 0.013
bwa brain washing 0.012
wit wishful thinking 0.012
Med Medea 0.012
Dip3 Dorsal interacting protein 3 0.012
Sac1 CG9128 gene product from transcript CG9128-RB 0.012
aly always early 0.012
Pk61C Protein kinase 61C 0.012
pasha partner of drosha 0.012
mael maelstrom 0.012
foxo forkhead box, sub-group O 0.012
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Kcnc3 potassium voltage gated channel, Shaw-related subfamily, member 3 0.063
Flt1 FMS-related tyrosine kinase 1 0.056
Calcrl calcitonin receptor-like 0.049
Insr insulin receptor 0.045
Pax8 paired box 8 0.041
Irs1 insulin receptor substrate 1 0.035
Rasgrp3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.034
A1cf APOBEC1 complementation factor 0.033
Nras neuroblastoma ras oncogene 0.029
Chsy1 chondroitin sulfate synthase 1 0.027
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.023
Abp1 amiloride binding protein 1 (amine oxidase, copper-containing) 0.023
Cyyr1 cysteine/tyrosine-rich 1 0.023
Pecam1 platelet/endothelial cell adhesion molecule 1 0.021
Pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.019
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.019
Gpr20 G protein-coupled receptor 20 0.018
Ptger1 prostaglandin E receptor 1 (subtype EP1) 0.017
Olr857 olfactory receptor 857 0.017
Cyfip1 cytoplasmic FMR1 interacting protein 1 0.017
Lepr leptin receptor 0.017
Nf1 neurofibromin 1 0.016
Brunol4 bruno-like 4, RNA binding protein (Drosophila) 0.016
Olr1469 olfactory receptor Olr1469 0.016
Kdr kinase insert domain receptor 0.016
Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor 0.016
Dlg4 discs, large homolog 4 (Drosophila) 0.015
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.014
Thbd thrombomodulin 0.014
Pla2g3 phospholipase A2, group III 0.014
Pgc progastricsin (pepsinogen C) 0.013
Map1a microtubule-associated protein 1A 0.013
Hcrtr1 hypocretin (orexin) receptor 1 0.013
Tgfbr3 transforming growth factor, beta receptor III 0.013
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.013
Vamp1 vesicle-associated membrane protein 1 0.013
Grb2 growth factor receptor bound protein 2 0.013
Lhb luteinizing hormone beta 0.013
Gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.012
Lims1 LIM and senescent cell antigen-like domains 1 0.012
Chrm2 cholinergic receptor, muscarinic 2 0.012
Mdfic MyoD family inhibitor domain containing 0.012
Opn1mw opsin 1 (cone pigments), medium-wave-sensitive 0.011
LOC100360403 ATP-binding cassette, sub-family C, member 9-like 0.011
Stc1 stanniocalcin 1 0.011
Fgfr4 fibroblast growth factor receptor 4 0.011
Cox5b cytochrome c oxidase subunit Vb 0.011
Olr1361 olfactory receptor 1361 0.011
Rbms1 RNA binding motif, single stranded interacting protein 1 0.011
Chia chitinase, acidic 0.011
Aqp5 aquaporin 5 0.011
F13a1 coagulation factor XIII, A1 polypeptide 0.010
Fam63b family with sequence similarity 63, member B 0.010
Colq collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism